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    Academic Journals

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• Gene expression profiling and histomorphometric analyses of the early bone healing response around nanotextured implants

  Authors:Rima M Wazen, Shingo Kuroda, Clarice Nishio, Karine Sellin, John B Brunski, and Antonio NanciFrom:Nanomedicine (Vol. 8, Issue 9) Peer-Reviewed

  Sept. 20135,059 words Report 1530LAuthor(s): Rima M Wazen 1 , Shingo Kuroda 1 2 , Clarice Nishio 1 , Karine Sellin 1 , John B Brunski 3 , Antonio Nanci [*] 4 Keywords : bone; DNA microarray; histomorphometry; nanotopography; titanium alloy...

• Collagen implants equipped with 'fish scale'-like nanoreservoirs of growth factors for bone regeneration

  Authors:Sandy Eap, Alice Ferrand, Jessica Schiavi, Laetitia Keller, Tunay Kokten, Florence Fioretti, et al.From:Nanomedicine (Vol. 9, Issue 8) Peer-Reviewed

  Aug. 20145,249 words Report 1440LAuthor(s): Sandy Eap 1 , Alice Ferrand 1 , Jessica Schiavi 1 , Laetitia Keller 1 , Tunay Kokten 1 2 , Florence Fioretti 1 2 , Didier Mainard 1 2 , Guy Ladam 4 , Nadia Benkirane-Jessel [*,] 1 2 3 Keywords: bone...

• Treatment of grade II furcation involvement using resorbable guided tissue regeneration membrane: A six-month study

  Authors:Deepti Khanna, Sumit Malhotra, and D. NaiduFrom:Journal of Indian Society of Periodontology (Vol. 16, Issue 3) Peer-Reviewed

  July-September 20123,422 words Report 1690LByline: Deepti. Khanna, Sumit. Malhotra, D. Naidu Aims: The present study was undertaken to evaluate the effectiveness of the combination of hydroxyapatite and [sz]-tricalcium phosphate bone alloplast with...

• From nano- to macro-scale: nanotechnology approaches for spatially controlled delivery of bioactive factors for bone and cartilage engineering

  Authors:Vitor E Santo, Manuela E Gomes, Joao F Mano, and Rui L ReisFrom:Nanomedicine (Vol. 7, Issue 7) Peer-Reviewed

  July 201213,437 words Report 1520LAuthor(s): Vítor E Santo 1 , Manuela E Gomes 1 , João F Mano 1 , Rui L Reis [*] 2 KEYWORDS : bone regeneration; cartilage regeneration; controlled release; gradients; growth factors; intracellular delivery;...

• The effect of housing environment on bone healing in a critical radius defect in New Zealand White rabbits

  Authors:Patricia Hedenqvist, Amela Trbakovic, Torbjorn Mellgren, Caroline Ohman-Magi, Petra Hammarstrom Johansson, Elin Manell, et al.From:PLoS ONE (Vol. 15, Issue 5) Peer-Reviewed

  May 21, 20206,331 words Report 1430LAuthor(s): Patricia Hedenqvist 1,*, Amela Trbakovic 2, Torbjörn Mellgren 3, Caroline Öhman-Mägi 3, Petra Hammarström Johansson 4, Elin Manell 1, Stina Ekman 5, Cecilia Ley 5, Marianne Jensen-Waern 1, Andreas Thor 2...

• Polycaprolactone nanofiber scaffold enhances the osteogenic differentiation potency of various human tissue-derived mesenchymal stem cells

  Authors:Ruyue Xue, Yuna Qian, Linhao Li, Guidong Yao, Li Yang, and Yingpu SunFrom:Stem Cell Research & Therapy (Vol. 8, Issue 1) Peer-Reviewed

  June 24, 20174,516 words Report 1490LBackground Polycaprolactone (PCL) has been regarded as a promising synthetic material for bone tissue engineering application. Owing to its unique biochemical properties and great compatibility, PCL fibers have come...

• Orthobiologics for fracture healing: opportunities and risks

  Authors:Philipp Leucht and J. Tracy WatsonFrom:AAOS NowPeer-Reviewed

  Oct. 20151,291 words Article 1390LUnderstanding of the biology of bone healing has increased dramatically, with a corresponding surge in the number of orthobiologics available for use in augmenting fracture healing and bone defect management. This often...

• Bone building with bortezomib

  Author:Roodman G. DavidFrom:Journal of Clinical Investigation (Vol. 118, Issue 2) Peer-Reviewed

  Feb. 20081,772 words Article 1390LIn this issue of the JCI, Mukherjee et al. report that bortezomib, a clinically available proteasome inhibitor active against myeloma, induces the differentiation of mesenchymal stem/progenitor cells (MSCs)--rather than...

• Inhibition of SDF-1/CXCR4 Axis to Alleviate Abnormal Bone Formation and Angiogenesis Could Improve the Subchondral Bone Microenvironment in Osteoarthritis.

  Authors:Hanjun Qin, Xingqi Zhao, Yan Jun Hu, Shengnan Wang, Yunfei Ma, Siying He, et al.From:BioMed Research International (Vol. 2021) Peer-Reviewed

  May 29, 20217,361 words Report 1340LThe pathogenesis of the osteoarthritis (OA) is complex. Abnormal subchondral bone metabolism is an important cause of this disease. Further understanding on the pathology of the subchondral bone in OA may provide a new...

• Comparison of rhBMP-2 in Combination with Different Biomaterials for Regeneration in Rat Calvaria Critical-Size Defects.

  Authors:Francisca Uribe, Bélgica Vásquez, Juan Pablo Alister, and Sergio OlateFrom:BioMed Research International (Vol. 2022) Peer-Reviewed

  Apr. 25, 20228,336 words Report 1270LRegeneration of critical bone defects requires the use of biomaterials. The incorporation of osteoinductive agents, such as bone morphogenetic proteins (BMPs), improves bone formation. This study aimed to compare the...

• J Biomed Mater Res B Appl Biomater.: The effect of PCL-TCP scaffold loaded with mesenchymal stem cells on vertical bone augmentation in dog mandible: a preliminary report

  Authors:A. Khojasteh, H. Behnia, and F.S. HosseiniFrom:Journal of Veterinary Dentistry (Vol. 30, Issue 1) Peer-Reviewed

  Spring 2013201 words Brief article, Repor... Polycaprolactone-tricalcium phosphate (PCL-TCP), a new composite scaffold, has been shown to facilitate early revascularization and speed up bone regeneration process. The objective of this study was to evaluate the...

• Regeneration potential of pulp-dentin complex: Systematic review

  Authors:R. Pramila and M. MuthuFrom:Journal of Conservative Dentistry (Vol. 15, Issue 2) Peer-Reviewed

  April-June 20123,233 words Report 1500LByline: R. Pramila, M. Muthu Aim: The aim is to review and discuss the strategies available for the regeneration of tooth tissues based on principles of tissue engineering. Background: Tissue engineering is a...

• New insights into osteogenic and chondrogenic differentiation of human bone marrow mesenchymal stem cells and their potential clinical applications for bone regeneration in pediatric orthopaedics

  Authors:Nicola Giuliani, Gina Lisignoli, Marina Magnani, Costantina Racano, Marina Bolzoni, Benedetta Dalla Palma, et al.From:Stem Cells InternationalPeer-Reviewed

  Annual 20139,512 words Report 1560LHuman mesenchymal stem cells (hMSCs) are pluripotent adult stem cells capable of being differentiated into osteoblasts, adipocytes, and chondrocytes. The osteogenic differentiation of hMSCs is regulated either by...

• Green Tea Extracts Epigallocatechin-3-gallate for Different Treatments

  Authors:Chenyu Chu, Jia Deng, Yi Man, and Yili QuFrom:BioMed Research International (Vol. 2017) Peer-Reviewed

  Annual 20177,199 words Report 1430LEpigallocatechin-3-gallate (EGCG), a component extracted from green tea, has been proved to have multiple effects on human pathological and physiological processes, and its mechanisms are discrepant in cancer,...

• Histomorphometrical evaluation of the effect of different amounts of 1, 25(OH) 2 D3 on bone healing in rabbit ulna

  Authors:Ahmad Asghari, Mohammad Mehdi Dehghan, and Aliasghar GharachorlouFrom:Advances in Environmental BiologyPeer-Reviewed

  June 20112,348 words Report 1440LVitamin D (calciferol) comprises a group of fat soluble seco-sterols found naturally only in a few foods. Lack of this vitamin causes some disorders in bone metabolism. In this study, 32 adult female New Zealandian...

• Mesenchymal stem cells and platelet gel improve bone deposition within CAD-CAM custom-made ceramic HA scaffolds for condyle substitution

  Authors:L. Ciocca, D. Donati, S. Ragazzini, B. Dozza, F. Rossi, M. Fantini, et al.From:BioMed Research InternationalPeer-Reviewed

  Annual 20137,131 words Report 1400LPurpose. This study evaluated the efficacy of a regenerative approach using mesenchymal stem cells (MSCs) and CAD- CAM customized pure and porous hydroxyapatite (HA) scaffolds to replace the temporomandibular joint...

• Lectins bring benefits to bones

  Authors:Charles KF Chan, Ryan C Ransom, and Michael T LongakerFrom:eLife (Vol. 5) Peer-Reviewed

  Dec. 13, 20161,614 words Report 1410LThe discovery that proteins called c-type lectins promote bone growth could lead to new treatments for age-related bone disorders. Byline: Charles KF Chan, Ryan C Ransom, Michael T Longaker...

• Combined treatment with electrical stimulation and insulin-like growth factor-1 promotes bone regeneration in vitro

  Authors:Zhiping Qi, Peng Xia, Su Pan, Shuang Zheng, Chuan Fu, Yuxin Chang, et al.From:PLoS ONE (Vol. 13, Issue 5) Peer-Reviewed

  May 10, 20186,347 words Report 1470LElectrical stimulation (ES) and insulin-like growth factor-1 (IGF-1) are widely used in bone regeneration because of their osteogenic activity. However, the combined effects of ES and supplemental IGF-1 on the whole...

• Efficacy of intraoperatively prepared cell-based constructs for bone regeneration

  Authors:Yang Zhang, Eline C Grosfeld, Winston A Camargo, Hongbo Tang, Angela M P Magri, and Jeroen J J P van den BeuckenFrom:Stem Cell Research & Therapy (Vol. 9, Issue 1) Peer-Reviewed

  Oct. 25, 20187,095 words Report 1460LBackground Conventional cell-based bone regeneration suffers from the major disadvantage of limited cell supply, time-consuming in vitro expansion cultures, and limited patient-friendliness related to cell isolation...

• Influences of donor and host age on human muscle-derived stem cell-mediated bone regeneration

  Authors:Xueqin Gao, Aiping Lu, Ying Tang, Johannes Schneppendahl, Andrea B. Liebowitz, Alex C. Scibetta, et al.From:Stem Cell Research & Therapy (Vol. 9, Issue 1) Peer-Reviewed

  Nov. 21, 20188,797 words Report 1590LBackground Human muscle-derived stem cells (hMDSCs) have been shown to regenerate bone efficiently when they were transduced with Lenti-viral bone morphogenetic protein 2 (LBMP2). However, whether the age of hMDSCs...