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Academic Journals
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From:Nature Medicine (Vol. 20, Issue 10) Peer-ReviewedA new study shows that plasma levels of branched-chain amino acids are elevated in subjects several years before they are diagnosed with pancreatic cancer. This may reflect breakdown of peripheral protein stores in the...
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From:PLoS ONE (Vol. 5, Issue 9) Peer-ReviewedHigh physical activity/aerobic fitness predicts low morbidity and mortality. Our aim was to identify the most up-regulated gene sets related to long-term physical activity vs. inactivity in skeletal muscle and adipose...
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From:International Journal of Pediatric Endocrinology (Vol. 2010) Peer-ReviewedLack of insulin results in a catabolic state in subjects with insulin-dependent diabetes mellitus which is reversed by insulin treatment. Amino acid supply, especially branched chain amino acids such as leucine,...
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From:PLoS ONE (Vol. 5, Issue 11) Peer-ReviewedBackground Metabolomics is the rapidly evolving field of the comprehensive measurement of ideally all endogenous metabolites in a biological fluid. However, no single analytic technique covers the entire spectrum of...
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From:PLoS ONE (Vol. 7, Issue 10) Peer-ReviewedOur previous studies revealed that the staphylococcal protein Gcp is essential for bacterial growth; however, the essential function of Gcp remains undefined. In this study, we demonstrated that Gcp plays an important...
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From:PLoS ONE (Vol. 10, Issue 6) Peer-ReviewedLysine residues can be post-translationally modified by various acyl modifications in bacteria and eukarya. Here, we showed that two major acyl modifications, acetylation and succinylation, were changed in response to...
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From:Diabetology & Metabolic Syndrome (Vol. 13, Issue 1) Peer-ReviewedBackground Coronary artery disease is a leading cause of morbidity and mortality among patients with diabetes. Previously, we demonstrated that branched-chain amino acids (BCAAs) showed cardioprotective effects against...
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From:Journal of Autism and Developmental Disorders (Vol. 50, Issue 2) Peer-ReviewedIn contrast to the well-observed associations between obesity, diabetes, and autism spectrum disorder (ASD), the roles of maternal dyslipidemia and sex disparity in ASD have not been well-studied. We examined the joint...
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From:PLoS ONE (Vol. 9, Issue 6) Peer-ReviewedBackground Recent studies have determined that branched-chain (BCAAs) and aromatic (AAAs) amino acids are strongly correlated with obesity and atherogenic dyslipidemia and are strong predictors of diabetes. However,...
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From:PLoS ONE (Vol. 16, Issue 11) Peer-ReviewedThis study evaluated the ability of Aspergillus niger and Trichoderma koningii to improve the quality of tea dregs (TDs) through solid-state fermentation as well as the value of the fermented tea dregs (FTDs) produced...
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From:PLoS ONE (Vol. 8, Issue 3) Peer-ReviewedAuthor(s): Pengxiang She 1 , Kristine C. Olson 1 , Yoshihiro Kadota 2 , Ayami Inukai 2 , Yoshiharu Shimomura 2 , Charles L. Hoppel 3 , Sean H. Adams 4 , Yasuko Kawamata 5 , Hideki Matsumoto 5 , Ryosei Sakai 5 , Charles...
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From:Revista Brasileira de Nutrição Esportiva (Vol. 5, Issue 28) Peer-ReviewedSupplementation with branched chain amino acids has been disseminated widely among practitioners of physical activities. Studies suggest the development of central fatigue during activity, its correlation brain...
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From:PLoS ONE (Vol. 8, Issue 9) Peer-ReviewedThe brown bear (Ursus arctos) hibernates for 5 to 6 months each winter and during this time ingests no food or water and remains anuric and inactive. Despite these extreme conditions, bears do not develop azotemia and...
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From:PLoS ONE (Vol. 8, Issue 2) Peer-ReviewedPostmenopausal osteoporosis is a complicated and multi-factorial disease. To study the metabolic profiles and pathways activated in osteoporosis, Eight rats were oophorectomized (OVX group) to represent postmenopausal...
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From:PLoS ONE (Vol. 2, Issue 7) Peer-ReviewedHuntington disease (HD) is a fatal neurodegenerative disorder, with no effective treatment. The pathogenic mechanisms underlying HD have not been elucidated, but weight loss, associated with chorea and cognitive...
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From:Oxidative Medicine and Cellular Longevity (Vol. 2020) Peer-ReviewedPrevious studies have disclosed the antihyperuricemic effect of polydatin, a natural precursor of resveratrol; however, the mechanisms of action still remain elusive. The present study was undertaken to evaluate the...
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From:Science (Vol. 281, Issue 5374) Peer-ReviewedA 20-residue protein (named Betanova) forming a monomeric, three-stranded, antiparallel [Beta] sheet was designed using a structural backbone template and an iterative hierarchical approach. Structural and...
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From:European Journal of Clinical Nutrition (Vol. 71, Issue 5) Peer-ReviewedBackground/Objectives: Branched chain amino acids (BCAA) are among nutrients strongly linked with insulin sensitivity (IS) measures. We investigated the effects of a chronic increase of BCAA intake on IS in two groups...
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From:Journal of Cancer Research and Therapeutics (Vol. 8, Issue 1) Peer-ReviewedByline: Kamon. Chaiyasit, Viroj. Wiwanitkit Sir, The use of branch chain amino acid supplementation in cancer is an interesting nutritional management in cancerous patients. [sup][1] Here, the author presents an...
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From:Revista Brasileira de Nutrição Esportiva (Vol. 6, Issue 36) Peer-ReviewedCurrently, the use of dietary supplements is the focus of major research about potential ergogenic effects on human physical performance. Athletes or physically active for health and quality of life seek to use dietary...