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Academic Journals
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From:Nature Medicine (Vol. 20, Issue 10) Peer-ReviewedA new study shows that plasma levels of branched-chain amino acids are elevated in subjects several years before they are diagnosed with pancreatic cancer. This may reflect breakdown of peripheral protein stores in the...
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From:PLoS ONE (Vol. 5, Issue 9) Peer-ReviewedHigh physical activity/aerobic fitness predicts low morbidity and mortality. Our aim was to identify the most up-regulated gene sets related to long-term physical activity vs. inactivity in skeletal muscle and adipose...
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From:PLoS ONE (Vol. 5, Issue 11) Peer-ReviewedBackground Metabolomics is the rapidly evolving field of the comprehensive measurement of ideally all endogenous metabolites in a biological fluid. However, no single analytic technique covers the entire spectrum of...
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From:PLoS ONE (Vol. 7, Issue 10) Peer-ReviewedOur previous studies revealed that the staphylococcal protein Gcp is essential for bacterial growth; however, the essential function of Gcp remains undefined. In this study, we demonstrated that Gcp plays an important...
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From:PLoS ONE (Vol. 10, Issue 6) Peer-ReviewedLysine residues can be post-translationally modified by various acyl modifications in bacteria and eukarya. Here, we showed that two major acyl modifications, acetylation and succinylation, were changed in response to...
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From:Diabetology & Metabolic Syndrome (Vol. 13, Issue 1) Peer-ReviewedBackground Coronary artery disease is a leading cause of morbidity and mortality among patients with diabetes. Previously, we demonstrated that branched-chain amino acids (BCAAs) showed cardioprotective effects against...
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From:Journal of Autism and Developmental Disorders (Vol. 50, Issue 2) Peer-ReviewedIn contrast to the well-observed associations between obesity, diabetes, and autism spectrum disorder (ASD), the roles of maternal dyslipidemia and sex disparity in ASD have not been well-studied. We examined the joint...
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From:International Journal of Pediatric Endocrinology (Vol. 2010) Peer-ReviewedLack of insulin results in a catabolic state in subjects with insulin-dependent diabetes mellitus which is reversed by insulin treatment. Amino acid supply, especially branched chain amino acids such as leucine,...
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From:PLoS ONE (Vol. 9, Issue 6) Peer-ReviewedBackground Recent studies have determined that branched-chain (BCAAs) and aromatic (AAAs) amino acids are strongly correlated with obesity and atherogenic dyslipidemia and are strong predictors of diabetes. However,...
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From:PLoS ONE (Vol. 16, Issue 11) Peer-ReviewedThis study evaluated the ability of Aspergillus niger and Trichoderma koningii to improve the quality of tea dregs (TDs) through solid-state fermentation as well as the value of the fermented tea dregs (FTDs) produced...
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From:Revista Brasileira de Nutrição Esportiva (Vol. 2, Issue 10) Peer-ReviewedThe objective of this study was review the effects of BCAA for muscle protein balance and central fatigue in exercise of long duration. It was analyzed 17 international scientific articles and 2 national scientific...
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From:PLoS ONE (Vol. 8, Issue 10) Peer-ReviewedAuthor(s): Emad Darvishi 1,2, Mansoor Omidi 1, Ali Akbar Shahnejat Bushehri 1, Ashkan Golshani 2,*, Myron L. Smith 2,* Introduction Infectious diseases are responsible for more than 17 million deaths each year...
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From:Biotechnology for Biofuels (Vol. 13, Issue 1) Peer-ReviewedBackground Schizochytrium species are known for their abundant production of docosahexaenoic acid (DHA). Low temperatures can promote the biosynthesis of polyunsaturated fatty acids (PUFAs) in many species. This study...
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From:Revista Brasileira de Nutrição Esportiva (Vol. 4, Issue 20) Peer-ReviewedThis study aims to determine whether supplementation with branched-chain amino acids are effective in preventing acute immunosuppression after a training jiu jitsu. Study participants were five male athletes practicing...
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From:Science (Vol. 281, Issue 5374) Peer-ReviewedA 20-residue protein (named Betanova) forming a monomeric, three-stranded, antiparallel [Beta] sheet was designed using a structural backbone template and an iterative hierarchical approach. Structural and...
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From:European Journal of Clinical Nutrition (Vol. 71, Issue 5) Peer-ReviewedBackground/Objectives: Branched chain amino acids (BCAA) are among nutrients strongly linked with insulin sensitivity (IS) measures. We investigated the effects of a chronic increase of BCAA intake on IS in two groups...
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From:Saudi Journal of Kidney Diseases and Transplantation (Vol. 23, Issue 6) Peer-ReviewedByline: M. Kumar, Aparna. Bitla, K. V. N.. Raju, Suchitra. Manohar, V. Kumar, Srinivasa Rao. Narasimha The nutritional status in chronic kidney disease (CKD) patients is a predictor of prognosis during the first...
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From:PLoS ONE (Vol. 8, Issue 11) Peer-ReviewedAuthor(s): Yuan Yan Sin 1, Laurel L. Ballantyne 1, Kamalika Mukherjee 1, Tim St. Amand 1, Lianna Kyriakopoulou 2, Andreas Schulze 2, Colin D. Funk 1,* Introduction The urea cycle disorders (UCDs) are a group of...
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From:PLoS ONE (Vol. 10, Issue 3) Peer-ReviewedIn the present study, prior to the establishment of a method for the clinical diagnosis of chronic fatigue in humans, we validated the utility of plasma metabolomic analysis in a rat model of fatigue using capillary...
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From:Diabetes (Vol. 59, Issue 10) Peer-ReviewedOBJECTIVE--The contribution of mitochondrial dysfunction to skeletal muscle insulin resistance remains elusive. Comparative proteomics are being applied to generate new hypotheses in human biology and were applied here...