Search Results

• • 714 

    Academic Journals

  • Sort by: sorttype.publication.date.desc Newest sorttype.publication.date.asc Oldest sorttype.relevance Relevance

• Activity of Ca [sup]2+ -activated Cl[sup]- channels contributes to regulating receptor- and store-operated Ca [sup]2+ entry in human pulmonary artery smooth muscle cells

  Authors:Aya Yamamura, Hisao Yamamura, Amy Zeifman, and Jason YuanFrom:Pulmonary Circulation (Vol. 1, Issue 2) Peer-Reviewed

  April-June 20116,525 words Report 1990LByline: Aya. Yamamura, Hisao. Yamamura, Amy. Zeifman, Jason. Yuan Intracellular Ca [sup]2+ plays a fundamental role in regulating cell functions in pulmonary arterial smooth muscle cells (PASMCs). A rise in cytosolic...

• Splice variants of the alpha subunit of the G protein Gs activate both adenylyl cyclase and calcium channels

  Authors:Rafael Mattera, Michael P. Graziano, Atsuko Yatani, Zhimin Zhou, Rolf Graf, Juan Codina, et al.From:Science (Vol. 243, Issue 4892) Peer-Reviewed

  Feb. 10, 19891,824 words Article Splice Variants of the [alpha] Subunit of the G Protein G.sub.s Activate Both Adenylyl Cyclase and Calcium Channels PURIFIED PREPARATIONS OF G.sub.s, the stimulatory regulatory component of adenylyl cyclase, or...

• Potentiation by the beta subunit of the ratio of ionic current to the charge movement in the cardiac calcium channel

  Authors:Alan Neely, Xiangyang Wei, Riccardo Olcese, Lutz Birnbaumer, and Enrico StefaniFrom:Science (Vol. 262, Issue 5133) Peer-Reviewed

  Oct. 22, 19932,402 words Article The voltage-activated rabbit cardiac calcium channel [alpha.sub.1] subunit was expressed in Xenopus oocytes. The charge movement of its voltage sensor was measured and related to the opening of the ion-conducting pore....

• Attenuation of L-Type Ca.sup.2+ Channel Expression and Vasomotor Response in the Aorta with Age in Both Wistar-Kyoto and Spontaneously Hypertensive Rats

  Authors:Toshihiko Fukuda, Takahiro Kuroda, Miki Kono, Takahisa Miyamoto, Mitsuru Tanaka, and Toshiro MatsuiFrom:PLoS ONE (Vol. 9, Issue 2) Peer-Reviewed

  Feb. 12, 20145,093 words Article 1480LAuthor(s): Toshihiko Fukuda, Takahiro Kuroda, Miki Kono, Takahisa Miyamoto, Mitsuru Tanaka, Toshiro Matsui * Introduction It has been reported that aging greatly affects vessel tone and arterial stiffness [1],...

• Mapacalcine Protects Mouse Neurons against Hypoxia by Blocking Cell Calcium Overload

  Authors:Hamid Moha ou Maati, Catherine Widmann, Djamila Sedjelmaci Bernard Gallois, Catherine Heurteaux, Marc Borsotto, and Michel HuguesFrom:PLoS ONE (Vol. 8, Issue 7) Peer-Reviewed

  July 2, 20138,077 words Report 1440LAuthor(s): Hamid Moha ou Maati 1, Catherine Widmann 1, Djamila Sedjelmaci Bernard Gallois, Catherine Heurteaux 1, Marc Borsotto 1,*, Michel Hugues 2,* Introduction Despite decades of research, the prognosis for...

• Drug-induced gingival overgrowth: A critical insight into case reports from over two decades

  Authors:Pramod Samudrala, Vijay Chava, Tanguturi Chandana, and Rachakonda SureshFrom:Journal of Indian Society of Periodontology (Vol. 20, Issue 5) Peer-Reviewed

  September-October 20165,013 words Article 1640LByline: Pramod. Samudrala, Vijay. Chava, Tanguturi. Chandana, Rachakonda. Suresh Drug-induced gingival overgrowth (DIGO) is a well-recognized adverse effect of certain systemic medications. Calcium channel blockers,...

• Nitric oxide protects L-type calcium channel of cardiomyocyte during long-term isoproterenol stimulation in tail-suspended rats

  Authors:Zhi-Jie Yue, Peng-Tao Xu, Bo Jiao, Hui Chang, Zhen Song, Man-Jiang Xie, et al.From:BioMed Research InternationalPeer-Reviewed

  Annual 20155,747 words Report 1330LThe aim of this study was to investigate the effects of nitric oxide (NO) and reactive oxygen species (ROS) on L-type calcium channel (LTCC) gating properties of cardiomyocytes during long-term isoproterenol (ISO)...

• RyR2 mutants have big hearts

  From:Journal of Clinical Investigation (Vol. 117, Issue 5) Peer-Reviewed

  May 2007182 words Brief article, Clini... 1540LRyR2 is a [Ca.sup.2+] release channel expressed by cardiac muscle cells that has an important role in cardiac excitation-contraction coupling. In vitro studies have shown that calmodulin (CaM) inhibits RyR2 function,...

• Diaphragm tension reduced in dystrophic mice by an oxidant, hypochlorous acid

  Authors:Aude Lafoux, Alexandra Divet, Pascal Gervier, and Corinne Huchet-CadiouFrom:Canadian Journal of Physiology and Pharmacology (Vol. 88, Issue 2) Peer-Reviewed

  Feb. 20106,878 words Report In dystrophin-deficient skeletal muscle cells, in which [Ca.sup.2+] homeostasis is disrupted and reactive oxygen species production is increased, we hypothesized that hypochlorous acid (HOCl), a strong...

• Effect of CatSper and Hv1 Channel Inhibition on Progesterone Stimulated Human Sperm

  Authors:Sara Keshtgar, Hamideh Ghanbari, Esmaeel Ghani, and Seyed Mostafa Shid MoosaviFrom:Journal of Reproduction and Infertility (Vol. 19, Issue 3) Peer-Reviewed

  July-September 20183,826 words Report 1270LBackground: Intracellular calcium and proton concentrations are important factors for activating human sperm. Calcium ion ([Ca.sup.2+]) enters sperm through voltage-dependent calcium channel of sperm (CatSper). Proton...

• Single cell expression analysis--pharmacogenomic potential

  Authors:A.K. Dixon, K. Lee, P.J. Richardson, M.I. Bell, and M.J. SkynnerFrom:Pharmacogenomics (Vol. 3, Issue 6) Peer-Reviewed

  Nov. 1, 20028,567 words Report 1440LA fundamental challenge in biology is to correlate physiology with gene expression in specific cell types. This can only be achieved by understanding gene expression at the level of the single cell because, in many...

• Levobupivacaine-induced contraction of isolated rat aorta is calcium dependent

  Authors:Ji Seok Baik, Ju-Tae Sohn, Seong-Ho Ok, Jae-Gak Kim, Hui-Jin Sung, Sang-Seung Park, et al.From:Canadian Journal of Physiology and Pharmacology (Vol. 89, Issue 7) Peer-Reviewed

  July 20115,022 words Report 1430LLevobupivacaine is a long-acting local anesthetic that intrinsically produces vasoconstriction in isolated vessels. The goals of this study were to investigate the calcium-dependent mechanism underlying...

• Gender specific click and tone burst evoked ABR datasets from mice lacking the Cav3.2 T-type voltage-gated calcium channel.

  Authors:Andreas Lundt, Christina Henseler, Carola Wormuth, Julien Soos, Robin Seidel, Ralf Müller, et al.From:BMC Research Notes (Vol. 12, Issue 1) Peer-Reviewed

  Mar. 20, 20191,661 words Article 1390LObjectives Voltage-gated Ca.sup.2+ channels (VGCCs) are of central relevance in regulating Ca.sup.2+ influx into living cells. The low-voltage activated (LVA) Ca.sub.v3 T-type Ca.sup.2+ channels are widely distributed...

• TRPV4 helps Piezo1 put the squeeze on pancreatic acinar cells.

  Authors:Fred Gorelick and Michael H. NathansonFrom:Journal of Clinical Investigation (Vol. 130, Issue 5) Peer-Reviewed

  May 20202,101 words Article 1440LAlterations in calcium signaling in pancreatic acinar cells can result in pancreatitis. Although pressure changes in the pancreas can elevate cytosolic calcium ([Ca.sup.2+]) levels, it is not known how transient...

• Contribution of [Ca.sup.2+]-dependent [Cl.sup.-] channels to norepinephrine-induced contraction of femoral artery is replaced by increasing EDCF contribution during ageing

  Authors:Silvia Liskova, Miriam Petrova, Petr Karen, Michal Behuliak, and Josef ZichaFrom:BioMed Research InternationalPeer-Reviewed

  Annual 20145,176 words Report 1480LThe activation of [Ca.sup.2+]-dependent [Cl.sup.-] channels during norepinephrine-induced contraction of vascular smooth muscle was suggested to depolarize cell membrane and to increase [Ca.sup.2+] entry. Hypertension...

• The Effects of Vitamin D Receptor Silencing on the Expression of LVSCC-A1C and LVSCC-A1D and the Release of NGF in Cortical Neurons

  Authors:Duygu Gezen-Ak, Erdinc Dursun, and Selma YilmazerFrom:PLoS ONE (Vol. 6, Issue 3) Peer-Reviewed

  Mar. 3, 20116,713 words Article 1490LBackground Recent studies have suggested that vitamin D can act on cells in the nervous system. Associations between polymorphisms in the vitamin D receptor (VDR), age- dependent cognitive decline, and insufficient...

• Correlations in Ion Channel mRNA in Rhythmically Active Neurons

  Authors:Anne-Elise Tobin, Nelson D. Cruz-Bermudez, Eve Marder, and David J. SchulzFrom:PLoS ONE (Vol. 4, Issue 8) Peer-Reviewed

  Aug. 25, 20096,479 words Article 1500LBackground To what extent do identified neurons from different animals vary in their expression of ion channel genes? In neurons of the same type, is ion channel expression highly variable and/or is there any...

• Glutathione Restores the Mechanism of Synaptic Plasticity in Aged Mice to That of the Adult

  Authors:Julie M. Robillard, Grant R. Gordon, Hyun B. Choi, Brian R. Christie, and Brian A. MacVicarFrom:PLoS ONE (Vol. 6, Issue 5) Peer-Reviewed

  May 31, 20115,316 words Article 1410LGlutathione (GSH), the major endogenous antioxidant produced by cells, can modulate the activity of N-methyl-D-aspartate receptors (NMDARs) through its reducing functions. During aging, an increase in oxidative stress...

• A critical role for STIM1 in filopodial calcium entry and axon guidance

  Authors:Sangwoo Shim, James Q Zheng, and Guo-li MingFrom:Molecular Brain (Vol. 6, Issue 1) Peer-Reviewed

  Dec. 1, 20138,950 words Report 1430LBackground Stromal interaction molecule 1 (STIM1), a Ca.sup.2+ sensor in the endoplasmic reticulum, regulates store-operated Ca.sup.2+ entry (SOCE) that is essential for Ca.sup.2+ homeostasis in many types of cells....

• Ion Channel Expression in the Developing Enteric Nervous System

  Authors:Caroline S. Hirst, Jaime P. P. Foong, Lincon A. Stamp, Emily Fegan, Stephan Dent, Edward C. Cooper, et al.From:PLoS ONE (Vol. 10, Issue 3) Peer-Reviewed

  Mar. 23, 20159,153 words Article 1610LThe enteric nervous system arises from neural crest-derived cells (ENCCs) that migrate caudally along the embryonic gut. The expression of ion channels by ENCCs in embryonic mice was investigated using a PCR-based...