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    Academic Journals

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• Tumor heterogeneity and implications for clinical practice

  Author:Edward ChuFrom:Oncology (Vol. 28, Issue 9) Peer-Reviewed

  Sept. 20141,030 words Article 1590LSince the late 1890s, when morphologic tumor heterogeneity was first described by pathologists, tumor heterogeneity has been recognized as an important and relevant clinical problem. From the discovery of tumor...

• Distinct expression of cytokeratin, N-cadherin and CD133 in circulating tumor cells of metastatic breast cancer patients

  Authors:Carolin Bock, Brigitte Rack, Jens Huober, Ulrich Andergassen, Udo Jeschke, and Sophie Doisneau-SixouFrom:Future Oncology (Vol. 10, Issue 10) Peer-Reviewed

  Aug. 20149,453 words Report 1620LAuthor(s): Carolin Bock aff1 , Brigitte Rack aff1 , Jens Huober aff2 , Ulrich Andergassen aff1 , Udo Jeschke aff1 , Sophie Doisneau-Sixou [*] aff3 KEYWORDS breast cancer; CD133; circulating tumor cells; EMT;...

• Melissa officinalis extract induces apoptosis and inhibits proliferation in colon cancer cells through formation of reactive oxygen species

  Authors:C. Weidner, M. Rousseau, A. Plauth, S.J. Wowro, C. Fischer, H. Abdel-Aziz, et al.From:Phytomedicine: International Journal of Phytotherapy & Phytopharmacology (Vol. 22, Issue 2) Peer-Reviewed

  Feb. 15, 20154,930 words Report 1510LABSTRACT Purpose: Efficient strategies for the prevention of colon cancer are extensively being explored, including dietary intervention and the development of novel phytopharmaceuticals. Safe extracts of edible...

• The effects of insulin and EGCG on PANC-1 cell survival

  Authors:Victoria Hodges, Michelle Tucci, and Hamed BenghuzziFrom:Journal of the Mississippi Academy of Sciences (Vol. 60)

  Apr. 20152,733 words Report 1380LThere is less than a thirty percent survival rate for patients with a localized pancreatic tumor, and less than a ten percent survival rate for patients with metastases. There are diverse findings on the...

• HAMLET: functional properties and therapeutic potential

  Authors:James Ho CS, Anna Rydstrom, Maria Trulsson, Johannes Balfors, Petter Storm, Manoj Puthia, et al.From:Future Oncology (Vol. 8, Issue 10) Peer-Reviewed

  Oct. 20128,266 words Report 1530LAuthor(s): James Ho CS 1 , Anna Rydström 1 , Maria Trulsson 1 , Johannes Bålfors 1 , Petter Storm 1 , Manoj Puthia 1 , Aftab Nadeem 1 , Catharina Svanborg [*] 2 Keywords * clinical studies; conserved death...

• Magnetic cells for cancer therapy: adopting magnets for cell-based cancer therapies

  Authors:K. Kaluza and R.G. VileFrom:Gene Therapy (Vol. 15, Issue 23) Peer-Reviewed

  Dec. 20081,213 words Report 1650LGene Therapy (2008) 15, 1511-1512; doi:10.1038/gt.2008.139; published online 21 August 2008 Finding cells that genuinely traffic to tumors has not been straightforward. Many have been tried, including T cells, (1,2)...

• The key to cancer? Scientists search for the mechanisms behind cancer spread

  From:Pharmaceutical Technology Europe (Vol. 20, Issue 12) Peer-Reviewed

  Dec. 2008279 words Brief article 1260LScientists have discovered the two key processes that allow cancer cells to change the way they move to spread through the body, according to the journal Cell. "The spreading of cancer cells from one part of the body...

• Effect of homeopathic treatment on gene expression in Copenhagen rat tumor tissues

  Authors:Rajesh L. Thangapazham, N.V. Rajeshkumar, Anuj Sharma, Jim Warren, Anoop K. Singh, John A. Ives, et al.From:Integrative Cancer Therapies (Vol. 5, Issue 4) Peer-Reviewed

  Dec. 20062,948 words Article 1790LBackground: Increasing evidence suggests that the inability to undergo apoptosis is an important factor in the development and progression of prostate cancer. Agents that induce apoptosis may inhibit tumor growth and...

• Diabetes Drug Forces Differentiation of Ca Cells

  Author:DAVID R. BRANCHFrom:Family Practice News (Vol. 29, Issue 10)

  May 15, 1999416 words Article MIAMI -- The oral diabetes drug troglitazone appears to convert malignant liposarcoma cells into more normal cells and may open up a new avenue of investigation for anticancer drug development, Dr. George D. Demetri...

• MicroRNA-618 modulates cell growth via targeting PI3K/Akt pathway in human thyroid carcinomas

  Authors:L. Yi and Y. YuanFrom:Indian Journal of Cancer (Vol. 52, Issue 7) Peer-Reviewed

  Dec. 20152,363 words Report 1450LByline: L. Yi, Y. Yuan OBJECTIVE: MicroRNAs (miRNAs) were popularly investigated in many cancers. The aim of this study was to evaluate the expression, role, and mechanism of microRNA-618 (miR-618) in human thyroid...

• Comparison of cisplatin sensitivity and the 18F fluoro-2-deoxy 2 glucose uptake with proliferation parameters and gene expression in squamous cell carcinoma cell lines of the head and neck

  Authors:Eva Henriksson, Elisabeth Kjellen, Bo Baldetorp, Par-Ola Bendahl, Ake Borg, Eva Brun, et al.From:Journal of Experimental & Clinical Cancer Research (Vol. 28) Peer-Reviewed

  Feb. 13, 20095,466 words Report Authors: Eva Henriksson (corresponding author) [1]; Elisabeth Kjellén [2]; Bo Baldetorp [2]; Pär-Ola Bendahl [2]; Åke Borg [2]; Eva Brun [2]; Fredrik Mertens [3]; Tomas Ohlsson [4]; Karin Rennstam [2]; Johan Wennerberg...

• Serum Starvation Induces DRAM Expression in Liver Cancer Cells via Histone Modifications within Its Promoter Locus

  Authors:Peihua Ni, Hong Xu, Changqiang Chen, Jiayi Wang, Xiangfan Liu, Yiqun Hu, et al.From:PLoS ONE (Vol. 7, Issue 12) Peer-Reviewed

  Dec. 12, 20124,926 words Article 1470LAuthor(s): Peihua Ni 1 , 2 , Hong Xu 3 , Changqiang Chen 2 , Jiayi Wang 2 , Xiangfan Liu 2 , Yiqun Hu 2 , Qishi Fan 2 , Zhaoyuan Hou 3 , * , Yang Lu 1 , * Introduction Inactivation of cell-death pathways is a...

• Transcriptional Suppression, DNA Methylation, and Histone Deacetylation of the Regulator of G-Protein Signaling 10 (RGS10) Gene in Ovarian Cancer Cells

  Authors:Mourad W. Ali, Ercan Cacan, Yuying Liu, Jennifer Young Pierce, William T. Creasman, Mandi M. Murph, et al.From:PLoS ONE (Vol. 8, Issue 3) Peer-Reviewed

  Mar. 22, 20138,546 words Article 1480LAuthor(s): Mourad W. Ali 1 , Ercan Cacan 2 , Yuying Liu 3 , Jennifer Young Pierce 4 , 5 , William T. Creasman 4 , 5 , Mandi M. Murph 1 , Rajgopal Govindarajan 1 , Scott T. Eblen 3 , 5 , Susanna F. Greer 2 , Shelley B....

• CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity

  Authors:Marian L. Burr, Christina E. Sparbier, Yih-Chih Chan, James C. Williamson, Katherine Woods, Paul A. Beavis, et al.From:Nature (Vol. 549, Issue 7670) Peer-Reviewed

  Sept. 7, 201710,029 words Report 1510LAuthor(s): Marian L. Burr (corresponding author) [1, 2, 3]; Christina E. Sparbier [1]; Yih-Chih Chan [1]; James C. Williamson [3]; Katherine Woods [4, 5]; Paul A. Beavis [1, 2]; Enid Y. N. Lam [1, 2]; Melissa A....

• Enhancer function in lung cancer cells

  Authors:Sayantani Ghosh Dastidar, Min Wu, and Sergei NechaevFrom:Proceedings of the North Dakota Academy of Science (Vol. 71) Peer-Reviewed

  Apr. 2017247 words Author abstract, Bri... Enhancers are regulatory regions of DNA that play significant roles in determining the fate of a cell. Enhancers can be present in active or inactive state in a cell and these states can directly affect gene expression....

• “Low-grade squamous intraepithelial lesion, cannot exclude high-grade:” TBS says “Don't Use It!” should I really stop it?

  Authors:Jeanine Chiaffarano, Melissa Alexander, Robert Rogers, Fang Zhou, Joan Cangiarella, Melissa Yee-Chang, et al.From:CytoJournal (Vol. 14, Issue 1) Peer-Reviewed

  January-December 20173,816 words Article 1700LByline: Jeanine. Chiaffarano, Melissa. Alexander, Robert. Rogers, Fang. Zhou, Joan. Cangiarella, Melissa. Yee-Chang, Paul. Elgert, Aylin. Simsir Background: The Bethesda System uses a two-tiered approach in the...

• Curcumin and its analogue induce apoptosis in leukemia cells and have additive effects with bortezomib in cellular and xenograft models

  Authors:L.I. Nagy, L.Z. Feher, G.J. Szebeni, M. Gyuris, P. Sipos, R. Alfoldi, et al.From:BioMed Research InternationalPeer-Reviewed

  Annual 20155,540 words Report 1390LCombination therapy of bortezomib with other chemotherapeutics is an emerging treatment strategy. Since both curcumin and bortezomib inhibit NF-[kappa]B, we tested the effects of their combination on leukemia cells. To...

• Computational analysis of mRNA expression profiles identifies the ITG family and PIK3R3 as crucial genes for regulating triple negative breast cancer cell migration

  Authors:Sukhontip Klahan, Mei-Shin Wu, Edward Hsi, Chi-Cheng Huang, Ming-Feng Hou, and Wei-Chiao ChangFrom:BioMed Research InternationalPeer-Reviewed

  Annual 20154,249 words Report 1360LTriple-negative breast cancer (TNBC) is an aggressive type of breast cancer that does not express estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor (Her2/neu). TNBC has worse...

• Garcinia dulcis fruit extract induced cytotoxicity and apoptosis in HepG2 liver cancer cell line

  Authors:Mohd Fadzelly Abu Bakar, Nor Ezani Ahmad, Monica Suleiman, Asmah Rahmat, and Azizul IshaFrom:BioMed Research InternationalPeer-Reviewed

  Annual 20155,272 words Report 1470LGarcinia dulcis or locally known in Malaysia as "mundu" belongs to the family of Clusiaceae. The study was conducted to investigate the anticancer potential of different parts of G. dulcis fruit extracts and their...

• RNA-based TWIST1 inhibition via dendrimer complex to reduce breast cancer cell metastasis

  Authors:James Finlay, Cai M. Roberts, Gina Lowe, Joana Loeza, John J. Rossi, and Carlotta A. GlackinFrom:BioMed Research InternationalPeer-Reviewed

  Annual 20156,634 words Report 1450LBreast cancer is the leading cause of cancer-related deaths among women in the United States, and survival rates are lower for patients with metastases and/or triple-negative breast cancer (TNBC; ER, PR, and Her2...