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Academic Journals
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From:Personalized Medicine (Vol. 10, Issue 3) Peer-ReviewedAuthor(s): Darren R Tyson [*] 1 , Vito Quaranta 2 KEYWORDS : cancer therapeutics; dynamic treatment response; single-cell analysis; tumor heterogeneity Cancer has been considered a genetic disease for over a...
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From:Indian Journal of Pathology and Microbiology (Vol. 56, Issue 2) Peer-ReviewedByline: Sree. Jinkala, Nachiappa. Rajesh, Arvind. Ramkumar Neurofibromatosis I (NF I), an autosomal dominant disorder is associated with increased risk of benign and malignant peripheral nerve sheath tumors and...
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From:Future Oncology (Vol. 9, Issue 11) Peer-ReviewedAuthor(s): Chunmei Guo 1 , Shuqing Liu 2 , Ming-Zhong Sun [*] 3 Keywords * Anxa1; biomarker; cancer; drug resistance; invasion; metastasis Annexins are Ca2+ -regulated, phospholipid-dependent,...
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From:Journal of Cancer Research and Therapeutics (Vol. 8, Issue 1) Peer-ReviewedByline: Wei. Zhai, Yun-Fei. Xu, Min. Liu, Jun-Hua. Zheng Context: Renal cell carcinoma (RCC) is a kidney cancer that originates in renal parenchyma and it is the most common type of kidney cancer with approximately...
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From:Primary Health Care (Vol. 20, Issue 2)Summary There has been a huge increase in prostate cancer rates in the UK over the past three decades, making it the most common cancer in men. The recent publication of revised guidelines for prostate cancer risk...
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From:Clinical Chemistry (Vol. 56, Issue 9) Peer-ReviewedBy any account, we have now entered the second decade of the "-omics revolution." High-throughput measurement techniques capable of surveying large segments of the genome or proteome were expected to rapidly expand the...
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From:Paediatric Nursing (Vol. 22, Issue 4) Peer-ReviewedSCIENTISTS HAVE identified two genes that could help in the search for new therapies for the childhood kidney cancer known as Wilms' tumour. The genes, called MYCN and FBXW7, provide an insight into how the disease...
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From:Pharmacogenomics (Vol. 11, Issue 8) Peer-ReviewedAuthor(s): Dimitrios H Roukos 1 KEYWORDS : breast; cancer genome; gastric cancer; molecular networks; trastuzumab resistance Despite advances in our understanding of the molecular basis of traditional single...
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From:Expert Review of Hematology (Vol. 4, Issue 2) Peer-ReviewedAuthor(s): Marina Bousquet [[dagger]â ] 1 , Harvey F Lodish 2 Keywords : diagnostic tool; leukemia; microRNA; oncogene; prognostic tool; tumor suppressor gene Leukemia is a complex disease with many...
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From:Expert Review of Endocrinology & Metabolism (Vol. 6, Issue 3) Peer-ReviewedAuthor(s): Mengqian Chen 1 , Richard Carkner 1 , Ralph Buttyan [[dagger]â ] 3 Keywords : androgen signaling; cyclopamine; Gli; hedgehog signaling; prostate cancer; Smoothened Hedgehog is a cell signaling...
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From:Pharmacogenomics (Vol. 11, Issue 11) Peer-ReviewedThe first signature gene capable of predicting cisplatin/vinorelbine treatment efficacy in non-small-cell lung cancer patients discovered. A collaborative study between the Princess Margaret Hospital (ON, Canada) and...
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From:Expert Review of Neurotherapeutics (Vol. 8, Issue 5) Peer-ReviewedPublished in the April issue of Cancer Cell , the researchers used a high-resolution genome topography scan (GTS) algorithm to identify gene copy alterations in human glioblastoma (GBM) primary samples and cell lines....
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From:Expert Review of Respiratory Medicine (Vol. 5, Issue 5) Peer-ReviewedAuthor(s): Wen Gao 1 , Jing Xu 1 , Yong-qian Shu [[dagger]] 2 Keywords : diagnosis; miRNAs; NSCLC; prevention Lung cancer is the leading cause of cancer-related death worldwide, with a 5-year survival rate...
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From:Personalized Medicine (Vol. 5, Issue 6) Peer-ReviewedAuthor(s): Sharon A Savage 1 Keywords : cancer; cancer risk; genome-wide association study; genomics; population genetics; SNP Genetic risk of cancer Cancer is a complex, multifactorial disease with...
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From:Pediatric Health (Vol. 2, Issue 2) Peer-ReviewedAuthor(s): Jan Styczynski 1 Keywords: acute lymphoblastic leukemia; acute myeloid leukemia; adults; children; individualized therapy; non-Hodgkin lymphoma; targeted therapy Definition of age groups The WHO...
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From:Pharmacogenomics (Vol. 9, Issue 12) Peer-ReviewedAuthor(s): Adam JW Paige [[dagger]] 1 , Robert Brown 1 KEYWORDS: drug resistance; miRNA; polymorphisms; promoter methylation Ovarian cancer is the fourth most common tumor type in women in the UK, with...
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From:Personalized Medicine (Vol. 4, Issue 1) Peer-ReviewedAuthor(s): Sudhir Srivastava [[dagger]] 1 , Paul D Wagner 1 Keywords: biomarkers; cancer; oncogenes; raloxifene; risk assessment; tamoxifen; tumor suppressor genes Successful application of personalized...
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From:Pharmacogenomics (Vol. 7, Issue 1) Peer-ReviewedAuthor(s): Michael A Gordon, Ji Gil, Bo Lu, Wu Zhang, Dongyun Yang, Jim Yun, Sylke Schneider, Susan Groshen, Syma Iqbal, Oliver A Press, Katrin Rhodes, Heinz-Josef Lenz [[dagger]] Keywords : cancer;...
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From:Alternative Medicine Review (Vol. 10, Issue 4) Peer-ReviewedHigh expression of epidermal growth factor receptor (EGFR) is found in a variety of solid tumors, including colorectal cancer. EGFR has been identified as a rational target for anticancer therapy. Curcumin, the yellow...
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From:Nursing Standard (Vol. 19, Issue 49) Peer-ReviewedSUMMARY The first vaccine produced against major human cancer was developed against the hepatitis B virus in 1984. Since then, researchers have been working to develop further vaccines, including one against human...