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    Academic Journals

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• C-cadherin ectodomain structure and implications for cell adhesion mechanisms

  Authors:Titus J. Boggon, 4th Earl of Dunmore, Sophie Chappuis-Flament, Ellen Wong, Barry M. Gumbiner, and Lawrence ShapiroFrom:Science (Vol. 296, Issue 5571) Peer-Reviewed

  May 17, 20023,474 words Article Cadherins are transmembrane proteins that mediate adhesion between cells in the so[id tissues of animals. Here we present the 3.1 angstrom resolution crystal structure of the whole, functional extracellular domain from...

• Solution structure of the epithelial cadherin domain responsible for selective cell adhesion

  Authors:Michael Overduin, Timothy S. Harvey, Stefan Bagby, Kit I. Tong, Patrick Yau, Masatoshi Takeichi, et al.From:Science (Vol. 267, Issue 5196) Peer-Reviewed

  Jan. 20, 19952,414 words Article Cadherins are calcium-dependent cell adhesion molecules containing extracellular repeats of approximately 110 amino acids. The three-dimensional structure of the amino-terminal repeat of mouse epithelial cadherin was...

• Increased levels of soluble forms of E-selectin and ICAM-1 adhesion molecules during human leptospirosis

  Authors:Loic Raffray, Claude Giry, Yoga Thirapathi, Anne-Helene Reboux, Marie-Christine Jaffar-Bandjee, and Philippe GasqueFrom:PLoS ONE (Vol. 12, Issue 7) Peer-Reviewed

  July 7, 20175,123 words Report 1380LLeptospirosis is a multisystemic zoonotic disease with infiltration of visceral organs by Leptospira. The capacity of the vascular endothelium to grant immune cell recruitment and activation in target organs during the...

• Desmosomes: integrators of mechanical integrity in tissues

  Authors:Kathleen J. Green, Andrew P. Kowalczyk, Elayne A. Bornslaeger, Helena L. Palka, and Suzanne M. NorvellFrom:The Biological Bulletin (Vol. 194, Issue 3) Peer-Reviewed

  June 19982,125 words Article The adhesion capacity of desmosomal cadherins was studied by expressing desmogleins and desmocollins along their related protein plakoglobin in normal nonadherent L cell fibroblasts. The desmoplakin (DP) connection...

• A break in the chain?

  Author:Keith BurridgeFrom:Nature (Vol. 440, Issue 7080) Peer-Reviewed

  Mar. 2, 20061,580 words Article 1440LHow chains of proteins link transmembrane cell-cell adhesion molecules to the cell's inner scaffold was standard textbook material. But recent research challenges the accepted model, opening a new chapter in the field....

• Biotech gets a grip on cell adhesion

  Author:John TravisFrom:Science (Vol. 260, Issue 5110) Peer-Reviewed

  May 14, 19932,447 words Article Researchers are discovering that cell adhesion molecules play a significant role in many aspects of human health, including wound healing, the common cold and cancer. Many biotechnology companies are engaged in cell...

• A role for pp125FAK in suppression of apoptosis in fibroblasts

  Author:Carol A. OteyFrom:The Biological Bulletin (Vol. 194, Issue 3) Peer-Reviewed

  June 19982,021 words Article The functions of pp125FAK, a tyrosine kinase responsible for secondary messenger cascade, were analyzed. The cellular signal transduction capabilities of integrins produced second messengers within the cytoplasm. FAK...

• Neuronal adhesion molecules signal through FGF receptor

  Author:Claire O'BrienFrom:Science (Vol. 267, Issue 5202) Peer-Reviewed

  Mar. 3, 19951,438 words Article Researchers have discovered that specific cell adhesion molecules (CAMs) initiate some cellular events needed for neurite outgrowth by activating the receptor for fibroblast growth factor (FGF). CAMs seem to 'highjack'...

• Angiotensin II Blockade Is Associated With Decreased Plasma Leukocyte Adhesion Molecule Levels in Diabetic Nephropathy

  Authors:STEEN ANDERSEN, CASPER G. SCHALKWIJK, COEN D.A. STEHOUWER, and HANS-HENRIK PARVINGFrom:Diabetes Care (Vol. 23, Issue 7) Peer-Reviewed

  July 20001,072 words Article The effects of blockade of the reninangiotensin (RAS) system on levels of circulating adhesion molecules in type 1 diabetic patients with diabetic nephropathy were assessed. ACE-inhibition and angiotensin II receptor...

• Discrimination between intracellular uptake and surface adhesion of bacterial pathogens

  Author:Ralph R. IsbergFrom:Science (Vol. 252, Issue 5008) Peer-Reviewed

  May 17, 19915,265 words Article Most bacterial pathogens initiate infectious diseases by adhering to host cells. Bacterial adherence to nonphagocytic cells usually leads to extracellular colonization; however, many invasive microorganisms enter host...

• Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing

  Authors:Bruce A. Cunningham, John J. Hemperly, Ben A. Murray, Ellen A. Prediger, Robert Brackenbury, and Gerald M. EdelmanFrom:Science (Vol. 236) Peer-Reviewed

  May 15, 19874,169 words Article Neural Cell Adhesion Molecule: Structure, Immunoglobulin-Like Domains, Cell Surface Modulation, and Alternative RNA Splicing CELL ADHESION HAS LONG BEEN RECOGNIZED AS A MAJORprimary process in embryonic development....

• The role of podial secretions in adhesion in two species of sea stars (Echinodermata)

  Authors:Patrick Flammang, Stephane Demeulenaere, and Michel JangouxFrom:The Biological Bulletin (Vol. 187, Issue 1) Peer-Reviewed

  Aug. 19946,046 words Article Individuals of Asterias rubens and Marthasterias glacialis use their podia in locomotion, anchorage, and feeding. Each podium consists of a stem with a disk at its tip. The stem allows the podium to lengthen, flex, and...

• Conformation and function of the N-linked glycan in the adhesion domain of human CD2

  Authors:Daniel F. Wyss, Johnathan S. Choi, Jing Li, Maria H. Knoppers, Kevin J. Willis, Antonio R.N. Arulanandam, et al.From:Science (Vol. 269, Issue 5228) Peer-Reviewed

  Sept. 1, 19954,424 words Article The adhesion domain of human CD2 bears a single N-linked carbohydrate. The solution structure of a fragment of CD2 containing the covalently bound high-mannose N-glycan...

• Gravitropism in the rhizoids of the alga Chara: a model system for microgravity research

  Author:John Z. KissFrom:The Biological Bulletin (Vol. 192, Issue 1) Peer-Reviewed

  Feb. 19971,360 words Article The alga Chara was utilized as a model for plant gravitropism due to the distinctive structural polarity of its vesicles located near the apex and the availability of data concerning its structure and gravitropic...

• The role of cell adhesion molecules in the development of IDDM: implications for pathogenesis and therapy

  Authors:Xiao-dong Yang, Sara A. Michie, Reina E. Mebius, Roland Tisch, Irving Weissman, and Hugh O. McDevittFrom:Diabetes (Vol. 45, Issue 6) Peer-Reviewed

  June 19964,950 words Article IDDM is a chronic inflammatory disease in which there is autoimmune-mediated organ-specific destruction of the insulin-producing [beta]cells in the pancreatic islets of Langerhans. The migration of autoreactive...

• Regulation of integrin function by the urokinase receptor

  Authors:Ying Wei, Matvey Lukashev, Daniel I. Simon, Sarah C. Bodary, Steven A. Rosenberg, Michael V. Doyle, et al.From:Science (Vol. 273, Issue 5281) Peer-Reviewed

  Sept. 13, 19963,936 words Article Integrin function is central to inflammation, immunity, and tumor progression. The urokinase-type plasminogen activator receptor (uPAR) and integrins formed stable complexes that both inhibited native integrin adhesive...

• Effect of a static magnetic field on Escherichia coli adhesion and orientation

  Authors:Lotfi Mhamdi, Nejib Mhamdi, Naceur Mhamdi, Philippe Lejeune, Nicole Jaffrezic, Noel Burais, et al.From:Canadian Journal of Microbiology (Vol. 62, Issue 11) Peer-Reviewed

  Nov. 20165,258 words Report 1530LThis preliminary study focused on the effect of exposure to 0.5 T static magnetic fields on Escherichia coli adhesion and orientation. We investigated the difference in bacterial adhesion on the surface of glass and...

• Chunghyuldan activates NOS mRNA expression and suppresses VCAM-1 mRNA expression in human endothelial cells

  Authors:Seong-Uk Park, Woo-Sang Jung, Sang-Kwan Moon, Chang-Nam Ko, Ki-Ho Cho, Young-Suk Kim, et al.From:Canadian Journal of Physiology and Pharmacology (Vol. 83, Issue 12) Peer-Reviewed

  Dec. 20054,549 words Article 1700LAbstract: Chunghyuldan (CHD), a combinatorial drug that has antihyperlipidemic and anti-inflammatory activities, has been shown to improve arterial stiffness and inhibit stroke recurrence in clinical study. To...

• X-ray reflectivity and grazing incidence diffraction studies of interaction between human adhesion/growth-regulatory galectin-1 and DPPE--GM1 lipid monolayer at an air/water interface

  Authors:J. Majewski, S. Andre, E. Jones, E. Chi, and H.-J. GabiusFrom:Biochemistry (Moscow) (Vol. 80, Issue 7) Peer-Reviewed

  July 20158,460 words Report 1580LThe specific interaction of ganglioside GM1 with the homodimeric (prototype) endogenous lectin galectin-1 triggers growth regulation in tumor and activated effector T cells. This proven biorelevance directed interest to...

• Rap1 GTPase regulation of adherens junction positioning and cell adhesion. (Reports)

  Authors:Andrea L. Knox and Nicholas H. BrownFrom:Science (Vol. 295, Issue 5558) Peer-Reviewed

  Feb. 15, 20022,509 words Article Cell-cell junctions are distributed evenly around the lateral circumference of cells within an epithelium. We find that the even distribution of adherens junctions is an active process that requires the small guanosine...