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Academic Journals
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From:Journal of Clinical Investigation (Vol. 124, Issue 7) Peer-ReviewedNOTCH-dependent signaling pathways are critical for normal bone remodeling; however, it is unclear if dysfunctional NOTCH activation contributes to inflammation-mediated bone loss, as observed in rheumatoid arthritis...
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From:Neural Regeneration Research (Vol. 8, Issue 4) Peer-ReviewedByline: Jun. Ding, Zhili. He, Juan. Ruan, Ying. Liu, Chengxin. Gong, Shenggang. Sun, Honghui. Chen Ciliary neurotrophic factor is the only known neurotrophic factor that can promote differentiation of hippocampal...
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From:Neural Regeneration Research (Vol. 9, Issue 12) Peer-ReviewedByline: Defeng. Zou, Yi. Chen, Yaxin. Han, Chen. Lv, Guanjun. Tu microRNAs (miRNAs) play an important regulatory role in the self-renewal and differentiation of stem cells. In this study, we examined the effects of...
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From:Journal of Clinical Investigation (Vol. 125, Issue 4) Peer-ReviewedBone marrow mesenchymal stem cells (BMSCs) exhibit an age-dependent reduction in osteogenesis that is accompanied by an increased propensity toward adipocyte differentiation. This switch increases adipocyte numbers and...
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From:Regenerative Medicine (Vol. 5, Issue 5)Author(s): Sandra Strassburg 1 , Stephen M Richardson 1 , Anthony J Freemont 1 , Judith A Hoyland [[dagger]] 2 KEYWORDS: co-culture; intervertebral disc regeneration; mesenchymal stem cells; nucleus pulposus...
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From:Science (Vol. 251, Issue 4995) Peer-ReviewedTHE MYOD GENE IS CAPABLE OF ACTIVATING PREVIOUSLY silent muscle-specific genes when introduced into a large variety of differentiated cell types with a viral long terminal repeat (LTR) used to promote constitutive...
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From:Science (Vol. 243, Issue 4894) Peer-ReviewedGenetic Control of Differentiation of the Caenorhabditis elegants Touch Receptor Neurons NERVOUS SYSTEMS CONSIST OF MANY TYPES OF NEURONS that differ from each other structurally and biochemically in such features as...
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From:Science (Vol. 271, Issue 5246) Peer-ReviewedEarly stages of T cell development are thought to include a series of coordinated interactions between thymocytes and other cells of the thymus. A monoclonal antibody specific for mouse CD81 was identified that blocked...
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From:Science (Vol. 270, Issue 5243) Peer-ReviewedImmune responses dominated by interleukin-4 (IL-4)-producing T helper type 2 ([T.sub.H]2) cells or by interferon [gamma] (IFN-[gamma])-producing T helper type 1 ([T.sub.H]1) cells express distinctive protection against...
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From:Neural Regeneration Research (Vol. 10, Issue 9) Peer-ReviewedByline: Xian-feng. Jiang, Kai. Yang, Xiao-qing. Yang, Ying-fu. Liu, Yuan-chi. Cheng, Xu-yi. Chen, Yue. Tu It remains poorly understood if carrier hardness, elastic modulus, and contact area affect neural stem cell...
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From:Stem Cells InternationalPeer-ReviewedHuman pluripotent stem cells (hPSCs) derived from either blastocyst stage embryos (hESCs) or reprogrammed somatic cells (iPSCs) can provide an abundant source of human neuronal lineages that were previously sourced from...
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From:Stem Cells InternationalPeer-ReviewedAccurate and noninvasive stem cell tracking is one of the most important needs in regenerative medicine to determine both stem cell destinations and final differentiation fates, thus allowing a more detailed picture of...
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From:PLoS ONE (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Sitao Wu 1 , Robert W. Li 2 , Weizhong Li 1 , Cong-jun Li 2 , * Introduction Short-chain fatty acids (SCFAs), such as acetate, propionate, and butyrate, are important nutrients in ruminants. SCFAs are...
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From:PLoS ONE (Vol. 7, Issue 2) Peer-ReviewedAuthor(s): Joel Gaston 1 , Beatriz Quinchia Rios 2 , Rebecca Bartlett 2 , Craig Berchtold 2 , Susan L. Thibeault 1 , 2 , * Introduction The unique mechano-environment of vocal fold mucosa includes its ability to...
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From:PLoS ONE (Vol. 9, Issue 2) Peer-ReviewedAuthor(s): Òscar Martorell 1,2, Anna Merlos-Suárez 3, Kyra Campbell 1,2, Francisco M. Barriga 3, Christo P. Christov 4, Irene Miguel-Aliaga 5, Eduard Batlle 3,6, Jordi Casanova 1,2, Andreu Casali 1,2,* Introduction...
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From:PLoS ONE (Vol. 9, Issue 1) Peer-ReviewedAuthor(s): Nichole M. Danzl 1, Seihwan Jeong 2, Yongwon Choi 3, Konstantina Alexandropoulos 2,* Introduction Normal development of T cells in the thymus depends on interactions between the T cell receptors (TCRs)...
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From:PLoS ONE (Vol. 8, Issue 3) Peer-ReviewedAuthor(s): Yun Li 1 , Qiao Zhang 1 , Arnaldo Carreira-Rosario 1 , Jean Z. Maines 1 , Dennis M. McKearin 2 , Michael Buszczak 1 , * Introduction Drosophila early germline development has served as a useful model...
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From:PLoS ONE (Vol. 9, Issue 3) Peer-ReviewedAuthor(s): Robert D. Prinz 1, Catherine M. Willis 1,2, Toin H. van Kuppevelt 4, Michael Klüppel 1,2,3,* Introduction The glycosaminoglycan chondroitin sulfate (CS) consists of linear chains of repeating...
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From:PLoS ONE (Vol. 9, Issue 3) Peer-ReviewedAuthor(s): Tao Pan 1,2, Junfeng Sun 3, Jiyi Hu 1, Yiwang Hu 1, Jun Zhou 1, Zhigang Chen 1, Dong Xu 2, Wenhong Xu 2, Shu Zheng 1, Suzhan Zhang 1,* Introduction Colorectal cancer (CRC) remains to be the third most...
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From:PLoS ONE (Vol. 9, Issue 3) Peer-ReviewedAuthor(s): Xiaoying Li 1, Hua Tao 1, Kewei Xie 1, Zhaohui Ni 1, Yucheng Yan 1, Kai Wei 1, Peter Y. Chuang 2, John Cijiang He 2,3, Leyi Gu 1,* Introduction Most glomerular diseases share the common features of...