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    Academic Journals

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• Receptor-mediated increase in rabies virus axonal transport

  Authors:Shani Gluska, Stefan Finke, and Eran PerlsonFrom:Neural Regeneration Research (Vol. 10, Issue 6) Peer-Reviewed

  June 20151,868 words Viewpoint essay 1600LByline: Shani. Gluska, Stefan. Finke, Eran. Perlson Rabies virus (RABV) of the rhabdoviridae family is a prototype neurotropic virus that causes a fatal disease, and is still a major risk mostly in developing...

• Estrogen regulates Hippo signaling via GPER in breast cancer

  Authors:Xin Zhou, Shuyang Wang, Zhen Wang, Xu Feng, Peng Liu, Xian-Bo Lv, et al.From:Journal of Clinical Investigation (Vol. 125, Issue 5) Peer-Reviewed

  May 20157,112 words Report 1370LThe G protein-coupled estrogen receptor (GPER) mediates both the genomic and nongenomic effects of estrogen and has been implicated in breast cancer development. Here, we compared GPER expression in cancerous tissue and...

• GITR expression on T-cell receptor-stimulated human CD8[sup]+ T cell in a JNK-dependent pathway

  Authors:Subhasis Chattopadhyay and Nitya ChakrabortyFrom:Indian Journal of Human Genetics (Vol. 15, Issue 3) Peer-Reviewed

  September-December 20091,918 words Report Byline: Subhasis. Chattopadhyay, Nitya. Chakraborty Glucocorticoid-induced tumor necrosis factor receptor (TNFR) (GITR) family-related gene is a member of the TNFR super family. GITR works as one of the...

• Epigenetic regulation by nuclear receptors

  Authors:Christopher D Green and Jing-Dong J HanFrom:Epigenomics (Vol. 3, Issue 1) Peer-Reviewed

  Feb. 20119,930 words Report 1480LAuthor(s): Christopher D Green 1 2 , Jing-Dong J Han [[dagger]] 3 KEYWORDS : acetyltransferase; coactivator; corepressor; deacetylase; demethylase; epigenetics; genome wide; histone; methyltransferase; nuclear...

• Liver X receptors: new drug targets to treat Type 2 diabetes?

  Authors:Knut R Steffensen and Jan-Ake GustafssonFrom:Future Lipidology (Vol. 1, Issue 2)

  Apr. 20065,834 words Report 1500LAuthor(s): Knut R Steffensen 1 , Jan-Åke Gustafsson 2 Keywords : apolipoproteins; cholesterol metabolism; dyslipidemia; glucose metabolism; insulin signaling; lipid biosynthesis; lipid transport; liver X...

• Thrombin switches on RANTES synthesis in RA. (Echo)

  From:Journal of Clinical Pathology (Vol. 55, Issue 12) Peer-Reviewed

  Dec. 2002248 words Brief article Researchers have shown for the first time that development of rheumatoid arthritis (RA) entails stimulation of synthesis of a chemokine by thrombin. They further suggest that the expression of the RANTES chemokine's...

• Small molecule fills hormone's shoes

  Author:Marcia BarinagaFrom:Science (Vol. 281, Issue 5374) Peer-Reviewed

  July 10, 1998826 words Article As diabetics who must inject themselves daily with insulin know only too well, a major disadvantage of protein drugs is that they can't be taken orally. Drug companies would love to find small compounds that mimic the...

• A randomised placebo controlled study to assess the effects of cholinergic treatment on muscarinic receptors in Alzheimer's disease

  Authors:P.M. Kemp, C. Holmes, S. Hoffmann, S. Wilkinson, M. Zivanovic, J. Thom, et al.From:Journal of Neurology, Neurosurgery and Psychiatry (Vol. 74, Issue 11) Peer-Reviewed

  Nov. 20032,683 words Article J Neurol Neurosurg Psychiatry 2003;74: 1567-1570 Objective: To determine the effects of cholinergic treatment on the muscarinic receptor in patients with Alzheimer's disease. Methods: 12 patients with mild to...

• Physiological regulation of G protein-linked signaling

  Authors:Andrew J. Morris and Craig C.6 MalbonFrom:Physiological Reviews (Vol. 79, Issue 4) Peer-Reviewed

  Oct. 199949,032 words Article G protein-linked signaling in vertebrates, the receptors involved and the regulatory processes, were discussed. The receptors, which include rhodopsin and chemokine receptors, are involved in different human responses....

• Point mutations in the human vitamin D receptor gene associated with hypocalcemic rickets

  Authors:Mark R. Hughes, Peter J. Malloy, Dirk G. Kieback, Robert A. Kesterson, J. Wesley Pike, David Feldman, et al.From:Science (Vol. 242, Issue 4886) Peer-Reviewed

  Dec. 23, 19881,809 words Article Point Mutations in the Human Vitamin D Receptor Gene Associated with Hypocalcemic Rickets AGENETIC LESION IN THE PATHWAY of vitamin D action has been suspected in the human disorder of hypocalcemic vitamin...

• Autologous peptides constitutively occupy the antigen binding site on Ia

  Authors:Soren Buus, Alessandro Sette, Sonia M. Colon, and Howard M. GreyFrom:Science (Vol. 242, Issue 4881) Peer-Reviewed

  Nov. 18, 19881,433 words Article Autologous Peptides Constitutively Occupy the Antigen Binding Site on Ia IN GENERAL, T CELLS OF THE HELPER subset recognize complexes of altered--that is, denatured or fragmented--protein antigen and MHC Ia molecules....

• Human insulin receptor gene

  Authors:Susumu Seino, Mitsuko Seino, and Graeme I. BellFrom:Diabetes (Vol. 39, Issue 2) Peer-Reviewed

  Feb. 19904,499 words Article The numerous effects of insulin, ranging from the stimulation of glucose uptake to enzyme modulation to the promotion of cell growth, are all mediated by the insulin receptor (INSR) on the cell surface. This molecule,...

• Discrimination between intracellular uptake and surface adhesion of bacterial pathogens

  Author:Ralph R. IsbergFrom:Science (Vol. 252, Issue 5008) Peer-Reviewed

  May 17, 19915,265 words Article Most bacterial pathogens initiate infectious diseases by adhering to host cells. Bacterial adherence to nonphagocytic cells usually leads to extracellular colonization; however, many invasive microorganisms enter host...

• Isolation and expression of functional high-affinity Fc receptor complementary DNAs

  Authors:Janet M. Allen and Brian SeedFrom:Science (Vol. 243, Issue 4889) Peer-Reviewed

  Jan. 20, 19891,215 words Article Isolation and Expression of Functional High-Affinity Fc Receptor Complementary DNAs THE MACROPHAGE-SPECIFIC RECEPTOR (FcRI) for the constant region (Fc) of immunoglobulin G (IgG) plays a central role in...

• Immunoprecipitation of insulin receptors from cultured human lymphocytes (IM-9 cells) by antibodies to pp60src

  Authors:Nicola Perrotti, Simeon I. Taylor, nancy D. Richert, Ulf R. Rapp, Ira H. Pastan, and Jesse RothFrom:Science (Vol. 227) Peer-Reviewed

  Feb. 15, 19852,033 words Article Immunoprecipitation of Insulin Receptors from Cultured Human Lymphocytes (IM-9 Cells) by Antibodies to pp60src The product of the v-erb B oncogene of avian erythroblastosis virus is a truncated form of the epidermal...

• Signaling by the Escherichia coli aspartate chemoreceptor Tar with a single cytoplasmic domain per dimer

  Authors:Ichiro Tatsuno, Michio Homma, Kenji Oosawa, and Ikuro KawagishiFrom:Science (Vol. 274, Issue 5286) Peer-Reviewed

  Oct. 18, 19961,647 words Article Many transmembrane receptors are oligomeric proteins. Binding of a ligand may alter the oligomeric state of the receptor, induce structural changes within the oligomer, or both. The bacterial aspartate chemoreceptor Tar...

• Role of fosaprepitant, a neurokinin Type 1 receptor antagonist, in morphine-induced antinociception in rats

  Authors:Pranav Prasoon, Shivani Gupta, Rahul Kumar, Mayank Gautam, Saroj Kaler, and Subrata RayFrom:Indian Journal of Pharmacology (Vol. 48, Issue 4) Peer-Reviewed

  July-August 20163,111 words Report 1490LByline: Pranav. Prasoon, Shivani. Gupta, Rahul. Kumar, Mayank. Gautam, Saroj. Kaler, Subrata. Ray Objectives: Opioids such as morphine form the cornerstone in the treatment of moderate to severe pain. However,...

• Cell-specific mineralocorticoid receptors: future therapeutic targets for stroke?

  Authors:Quynh Dinh, Grant Drummond, Christopher Sobey, and Sophocles ChrissobolisFrom:Neural Regeneration Research (Vol. 11, Issue 8) Peer-Reviewed

  Aug. 20162,426 words Report 1550LByline: Quynh. Dinh, Grant. Drummond, Christopher. Sobey, Sophocles. Chrissobolis The mineralocorticoid receptor (MR), well known to be expressed in renal epithelial cells where it is important in fluid and...

• Public antibodies to malaria antigens generated by two LAIR1 insertion modalities

  Authors:Kathrin Pieper, Joshua Tan, Luca Piccoli, Mathilde Foglierini, Sonia Barbieri, Yiwei Chen, et al.From:Nature (Vol. 548, Issue 7669) Peer-Reviewed

  Aug. 31, 20178,118 words Report 1650LAuthor(s): Kathrin Pieper [1]; Joshua Tan [1, 2]; Luca Piccoli [1]; Mathilde Foglierini [1, 3]; Sonia Barbieri [1]; Yiwei Chen [1, 4]; Chiara Silacci-Fregni [1]; Tobias Wolf [1, 4]; David Jarrossay [1]; Marica Anderle...

• The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL

  Authors:Paul J Emmerson, Feng Wang, Yong Du, Qian Liu, Richard T Pickard, Malgorzata D Gonciarz, et al.From:Nature Medicine (Vol. 23, Issue 10) Peer-Reviewed

  Oct. 20176,362 words Report 1480LAuthor(s): Paul J Emmerson [1]; Feng Wang [2]; Yong Du [2]; Qian Liu [2]; Richard T Pickard [1]; Malgorzata D Gonciarz [1]; Tamer Coskun [1]; Matthew J Hamang [1]; Dana K Sindelar [1]; Kimberly K Ballman [1]; Lisa A...