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From:Emerging Infectious Diseases (Vol. 17, Issue 11) Peer-ReviewedOn October 19, 2010, the Haitian Ministry of Public Health and Population (MSPP) was notified of increased cases of acute watery diarrhea resulting in death among adults in Artibonite Department. Within 2 days, MSPP's...
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From:Weekly Epidemiological Record (Vol. 83, Issue 18)Between 5 March and 22 April 2008, the Ministry of Health of Viet Nam reported 2490 cases of severe acute watery diarrhoea, including 377 cases positive for Vibrio cholerae, the bacterium that causes cholera. The...
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From:PLoS ONE (Vol. 9, Issue 2) Peer-ReviewedAuthor(s): Victorien Decoin, Corinne Barbey, Dorian Bergeau, Xavier Latour, Marc G. J. Feuilloley, Nicole Orange, Annabelle Merieau * Introduction Bacteria have developed an arsenal of mechanisms, including...
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From:PLoS ONE (Vol. 8, Issue 5) Peer-ReviewedAuthor(s): Xiao Liang Dou 1, Rong Liang Qin 1, Juan Qu 2, Yong Hui Liao 2, Ya cheng Lu 2, Ting Zhang 2, Chen Shao 1,*, Yun Qing Li 2,* Introduction The micturition reflex is an autonomic reflex that is mediated by...
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From:PLoS ONE (Vol. 9, Issue 3) Peer-ReviewedAuthor(s): Matej Skocaj 1, Natasa Resnik 2, Maja Grundner 3, Katja Ota 1, Nejc Rojko 1, Vesna Hodnik 1, Gregor Anderluh 1,4, Andrzej Sobota 5, Peter Macek 1, Peter Veranic 2,*, Kristina Sepcic 1,* Introduction...
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From:Canadian Journal of Microbiology (Vol. 55, Issue 11) Peer-ReviewedVibrio cholerae activates proinflammatory response in cultured intestinal epithelial cells. In this study, we demonstrate that V. cholerae 0395 infection of intestinal epithelial cells results in the activation of Akt....
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From:Avicenna Journal of Medical Biotechnology (Vol. 4, Issue 2) Peer-ReviewedCholera toxin B subunit (CTB) has been extensively studied as an immunogen, adjuvant, and inducer of oral tolerance in many investigations. Production of CTB has been carried out in the bacterial, plant, insect and...
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From:BMC Research Notes (Vol. 12, Issue 1) Peer-ReviewedObjective The objectives of this research were to screen anti-quorum sensing activity of phyllosphere bacteria and quantify their antibiofilm activity against biofilm forming bacteria (Bacillus cereus, Staphylococcus...
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From:Nature (Vol. 568, Issue 7752) Peer-ReviewedA strain of cholera bacterium collected during the First World War is sequenced after decades in storage. A strain of cholera bacterium collected during the First World War is sequenced after decades in storage....
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From:eLife (Vol. 9) Peer-ReviewedBacteria, bacteriophages that prey upon them, and mobile genetic elements (MGEs) compete in dynamic environments, evolving strategies to sense the milieu. The first discovered environmental sensing by phages, lysis...
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From:Journal of Health, Population and Nutrition (Vol. 24, Issue 1) Peer-ReviewedThe study compared the safety and efficacy of an oral rehydration salts (ORS) solution, containing 75 mmol/L of sodium and glucose each, with the standard World Health Organization (WHO)-ORS solution in the management...
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From:PeerJ (Vol. 4) Peer-ReviewedA ferredoxin:NAD.sup.+ oxidoreductase was recently discovered as a redox-driven ion pump in the anaerobic, acetogenic bacterium Acetobacterium woodii. The enzyme is assumed to be encoded by the rnf genes. Since these...
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From:PLoS ONE (Vol. 8, Issue 12) Peer-ReviewedV. cholerae can form sessile biofilms associated with abiotic surfaces, cyanobacteria, zoo-plankton, mollusks, or crustaceans. Along with the vibrio polysaccharide, secreted proteins of the rbm gene cluster are key to...
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From:PLoS ONE (Vol. 6, Issue 1) Peer-ReviewedBackground We previously reported that the immunogenicity of Hc[beta]tre, a botulinum neurotoxin A (BoNT/A) immunogen, was enhanced by fusion to an epithelial cell binding domain, Ad2F, when nasally delivered to mice...
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From:PLoS ONE (Vol. 7, Issue 8) Peer-ReviewedThe luciferase protein fragment complementation assay is a powerful tool for studying protein-protein interactions. Two inactive fragments of luciferase are genetically fused to interacting proteins, and when these two...
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From:eLife (Vol. 6) Peer-ReviewedA structural switch controls the architecture of Vibrio cholerae biofilms by mediating the interactions between two matrix components. Byline: Xavier Pierrat, Alexandre Persat...
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From:PLoS ONE (Vol. 12, Issue 8) Peer-ReviewedDespite availability of high quality medical records, health care systems often do not have the resources or tools to utilize these data efficiently. Yet, hospital-based, laboratory-confirmed records may pave the way...
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From:PLoS ONE (Vol. 9, Issue 7) Peer-ReviewedBackground A live oral cholera vaccine VA 1.4 developed from a non-toxigenic Vibrio cholerae O1 El Tor strain using ctxB gene insertion was further developed into a clinical product following cGMP and was evaluated...
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From:Emerging Infectious Diseases (Vol. 20, Issue 1) Peer-ReviewedCholera remains a major public health problem. To compare the relative contribution of strains from the environment with strains isolated from patients during outbreaks, we performed multilocus variable tandem repeat...
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From:Diabetes (Vol. 48, Issue 11) Peer-ReviewedRestoration of peripheral tolerance to target autoantigens during autoimmune diseases has met with several limitations because of the limited efficacy of this approach in an already immune host. To optimize the...