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• Candidate prognostic markers in breast cancer: focus on extracellular proteases and their inhibitors

  Authors:David M. Roy and Logan A. WalshFrom:Breast Cancer: Targets and Therapy (Vol. 6) Peer-Reviewed

  Annual 20147,474 words Report 1930LThe extracellular matrix (ECM) is the complex network of proteins that surrounds cells in multicellular organisms. Due to its diverse nature and composition, the ECM has a multifaceted role in both normal tissue...

• The comparison of some levels in restrictive and non-restrictive cytokines in men runners

  Authors:Seyed Mahmoud Hejazi and Hasan BagheriFrom:Advances in Environmental BiologyPeer-Reviewed

  July 23, 20144,265 words Report 1820LIntroduction: The purpose of this research was the comparison of the level of some restrictive and nonrestrictive cytokines in men runners. Methodology: This study has been a post-in cadence causal applied research that...

• Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies

  Authors:Judy H. Cho and Marc FeldmanFrom:Nature Medicine (Vol. 21, Issue 7) Peer-Reviewed

  July 20157,953 words Report 1390LRecent advances in genome-wide association studies (GWAS) across autoimmune and immune-mediated diseases have augmented our understanding of pathogenic mechanisms underlying these diseases. This has further highlighted...

• Circulating sCD138 and some angiogenesis-involved cytokines help to anticipate the disease progression of early-stage B-cell chronic lymphocytic leukemia

  Authors:Jaroslaw Dybko, Bozena Jazwiec, Katarzyna Kapelko-Slowik, Kazimierz Kuliczkowski, Stanislaw Potoczek, Beata Tomaszewska-Toporska, et al.From:Mediators of InflammationPeer-Reviewed

  Annual 20063,904 words Clinical report 1610LSyndecan-1 (CD138) is a transmembrane heparin sulfate proteoglycan expressed on distinct stages of differentiation of Blymphoid cells. Its prognostic value in B-cell chronic lymphocytic leukemia (B-CLL) has not been...

• Single nucleotide polymorphic macrophage cytokine regulation by Mycobacterium tuberculosis and drug treatment

  Authors:Amit K Singh, Awadh Bihari Yadav, Rajiv Garg, and Amit MisraFrom:Pharmacogenomics (Vol. 15, Issue 4) Peer-Reviewed

  Mar. 20146,209 words Report 1470LAuthor(s): Amit K Singh 1 , Awadh Bihari Yadav 1 , Rajiv Garg 2 , Amit Misra [*] 3 KEYWORDS : inhalable microparticles; interleukin 10; interleukin 4; isoniazid; rifabutin; SNPs; tumor necrosis factor...

• Predictors of response to targeted therapy in renal cell carcinoma

  Authors:Laurie J. Eisengart, Gary R. MacVicar, and Ximing J. YangFrom:Archives of Pathology & Laboratory Medicine (Vol. 136, Issue 5) Peer-Reviewed

  May 20126,187 words Article 1930L* Context.--The prognosis for patients with metastatic renal cell carcinoma is poor, with an average 5-year survival of approximately 10%. Use of traditional cytokine therapy, specifically high-dose interleukin 2, is...

• Effects of phototherapy on Cytokines' levels and white blood cells in term neonate with hyperbilirubinemia

  Authors:Mousa Ahmadpour-Kacho, Sedigheh Jahanshahifard, and Yadollah PashaFrom:Journal of Clinical Neonatology (Vol. 1, Issue 3) Peer-Reviewed

  July-September 20122,161 words Report 1530LByline: Mousa. Ahmadpour-Kacho, Sedigheh. Jahanshahifard, Yadollah. Pasha Objective: Phototherapy is the most common treatment used for severe jaundice. There is increasing evidence that phototherapy can directly...

• Trigonella foenum-graecum ameliorates acrylamide-induced toxicity in rats: Roles of oxidative stress, proinflammatory cytokines, and DNA damage

  Authors:Mohamed M. Abdel-Daim, Mabrouk A. Abd Eldaim, and Abeer G.A. HassanFrom:Biochemistry and Cell Biology (Vol. 93, Issue 3) Peer-Reviewed

  June 20155,932 words Report 1530LAbstract: Acrylamide is a hazardous substance inducing oxidative stress. Based on some evidence on the antioxidant properties of fenugreek, Trigonella foenum-graecum, this study was conducted to investigate the...

• Methylene blue treatment for cytokine release syndrome-associated vasoplegia following a renal transplant with rATG infusion: a case report and literature review

  Authors:John T. Denny, Andrew T. Burr, Fred Balzer, James T. Tse, Julia E. Denny, and Darrick ChyuFrom:Experimental and Therapeutic Medicine (Vol. 9, Issue 5) Peer-Reviewed

  May 20155,813 words Clinical report 1490LRabbit anti-thymocyte globulin (rATG) is an infusion of polyclonal rabbit-derived antibodies against human thymocyte markers, which can be used to prevent and treat acute rejection following organ transplantation....

• Human leucocyte antigens and cytokine gene polymorphisms and tuberculosis

  Authors:A. Akgunes, A. Coban, and B. DurupinarFrom:Indian Journal of Medical Microbiology (Vol. 29, Issue 1)

  January-March 20112,950 words Article 1610LByline: A. Akgunes, A. Coban, B. Durupinar Purpose: Several genes encoding different cytokines and human leucocyte antigens (HLA) may play crucial roles in host susceptibility to tuberculosis (TB). Our objective was...

• Evasion through evolution

  Author:Kevin Da SilvaFrom:Nature Medicine (Vol. 17, Issue 3) Peer-Reviewed

  Mar. 2011166 words Brief article, Repor... 1380LViruses can evade clearance by host cells by inhibiting the host innate immune response. Upon infection, microbial components are sensed by a variety of host cell receptors, leading to activation of a multiprotein...

• Cytokine-induced killer cell trafficking to tumors: a chemokine-directed migration

  Author:Tobi L. SchmidtFrom:Journal of Interferon & Cytokine Research (Vol. 31, Issue 2) Peer-Reviewed

  Feb. 2011410 words Report 1400LCytokine-induced killer (CIK) cells are ex vivo expanded T-cells with immune effector function capable of in vitro and in vivo anticancer activity. The tumoricidal activity of CIK cells is attributed to a CD3+ CD56+...

• Researchers from University of Oxford Provide Details of New Studies and Findings in the Area of Colon Cancer (Macrophage migration inhibitory factor: A key cytokine and therapeutic target in colon cancer)

  From:Obesity, Fitness & Wellness Week

  Sept. 19, 2015387 words Brief article 1410L2015 SEP 19 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators discuss new findings in Oncology. According to news reporting from Oxford, United Kingdom, by NewsRx...

• Platelet-rich plasma injections for tendinopathy and osteoarthritis

  Authors:Isabel Andia and Michele AbateFrom:International Journal of Clinical Rheumatology (Vol. 7, Issue 4) Peer-Reviewed

  Aug. 20129,805 words Article 1440LAuthor(s): Isabel Andia [*] 1 , Michele Abate 2 KEYWORDS : angiogenesis; cytokines; growth factors; inflammation; injection therapies; osteoarthritis; platelet-rich plasma; tendinopathy Among the many...

• New Findings from Banner Sun Health Research Institute in Alzheimer Disease and Genetics Provides New Insights (Expression Of Suppressor Of Cytokine Signaling Genes In Human Elderly And Alzheimer's Disease Brains And Human Microglia)

  From:Obesity, Fitness & Wellness Week

  Sept. 5, 2015498 words Report 1520L2015 SEP 5 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New research on Neurodegenerative Diseases is the subject of a report. According to news reporting from Sun City,...

• Investigation of the effects of curcumin on serum cytokines in obese individuals: a randomized controlled trial

  Authors:Shiva Ganjali, Amirhossein Sahebkar, Elahe Mahdipour, Khadijeh Jamialahmadi, Sepideh Torabi, Saeed Akhlaghi, et al.From:The Scientific World Journal (Vol. 14) Peer-Reviewed

  Annual 20143,901 words Report 1530LBackground. Obesity is a disorder often accompanied by a heightened state of systemic inflammation and immunoactivation. The present randomized crossover trial aimed to investigate the efficacy of curcumin, a bioactive...

• Exploiting cytokines in adoptive T-cell therapy of cancer

  Authors:Elisabetta Petrozziello, Tabea Sturmheit, and Anna MondinoFrom:Immunotherapy (Vol. 7, Issue 5) Peer-Reviewed

  May 20158,576 words Report 2160LAuthor(s): Elisabetta Petrozziello aff1 , Tabea Sturmheit aff1 aff2 , Anna Mondino [*] aff1 Keywords: adoptive T-cell therapy; common [gamma]-chain cytokines; hematological malignancies; innate and adaptive immune...

• Effects of mycobacterial trehalose 6,6'-dimycolate on the innate immune system

  Author:Kaori SakamotoFrom:Journal of Interferon & Cytokine Research (Vol. 29, Issue 1) Peer-Reviewed

  Jan. 2009349 words Brief article, Repor... 1540LThe hallmark response to infection with Mycobacterium tuberculosis (Mtb) is the granuloma. This immune response consists primarily of different types of macrophages that may or may not be infected, surrounded by a...

• Breast cancer cells stimulate osteoprotegerin (OPG) production by endothelial cells through direct cell contact

  Authors:Penny E. Reid, Nicola J. Brown, and Ingunn HolenFrom:Molecular Cancer (Vol. 8) Peer-Reviewed

  July 15, 20095,717 words Report Authors: Penny E Reid [1]; Nicola J Brown [1]; Ingunn Holen (corresponding author) [1] Background Angiogenesis, the sprouting of capillaries from existing blood vessels, is central to tumour growth and progression...

• Update on oral lichen planus

  Authors:Marco Carrozzo and Rebecca J ThorpeFrom:Expert Review of Dermatology (Vol. 4, Issue 5) Peer-Reviewed

  Oct. 20099,142 words Article 1570LAuthor(s): Marco Carrozzo [[dagger]] 1 , Rebecca J Thorpe 2 Keywords: amalgam; calcineurin inhibitor; hepatitis C virus; oral cancer; oral lichen planus; pathogenesis; topical corticosteroid Oral lichen planus...