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From:Saudi Journal of Kidney Diseases and Transplantation (Vol. 24, Issue 6) Peer-ReviewedByline: Mohamed. Ahmed, Githa. Kishore, Hafeez. Khader, Meera. Kasturirangan To determine the risk factors for nephropathy in diabetic patients and to study the management of diabetic nephropathy (DN), we conducted a...
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From:Japanese Clinical MedicinePeer-ReviewedLow protein diet (LPD) plays an important role in preventing the progression of diabetic nephropathy. However, it is a great burden to the patients. In this paper, we have studied the quality of life (QOL) in such...
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From:Journal of Diabetes Nursing (Vol. 14, Issue 2) Peer-Reviewed5.14. NEPHROPATHY To care for people at risk of, or with nephropathy, you should be able to: 1. Unregistered * Demonstrate an awareness that all people practitioner with diabetes are at risk of nephropathy. * Perform...
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From:Renal & Urology News (Vol. 9, Issue 2)ADDING spironolactone to a regimen that includes maximal ACE inhibition improves renoprotection in hypertensive patients with diabetic nephropathy, data suggest. The finding is based on a placebo-controlled,...
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From:Obesity, Fitness & Wellness WeekA report, 'Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy,' is newly published data in Kidney International. "The accumulation of advanced...
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From:Diabetes (Vol. 55, Issue 11) Peer-ReviewedThe activation of the poly(ADP-ribose) polymerase (PARP) plays an important role in the pathophysiology of various diseases associated with oxidative stress. We found increased amounts of poly(ADP) ribosylated proteins...
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From:Diabetes Care (Vol. 23, Issue 6) Peer-ReviewedDiabetic nephropathy is a clinical syndrome that is characterized by persistent albuminuria, an increase in blood pressure, a relentless decline in kidney function, and increased cardiovascular morbidity and mortality....
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From:Diabetes (Vol. 49, Issue 5) Peer-ReviewedAccumulation of AGE plays an important role in the complications of diabetes mellitus. Aminoguanidine is known to inhibit AGE formation and has been extensively examined in animals. However, aminoguanidine causes...
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From:Diabetes (Vol. 38, Issue 9) Peer-ReviewedDiabetic nephropathy leading to kidney failure is a major complication of both type I (insulin-dependent) and type II (non-insulin-dependent) diabetes mellitus, and glomerular structural lesions (especially expansion of...
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From:The Egyptian Journal of Internal Medicine (Vol. 27, Issue 3) Peer-ReviewedByline: Ebtessam. Zakaria, Maha. Al-Din, Nashwa. Ghanem, Noha. Sadik, Maha. Assem, Fatma. Taha Background Diabetic nephropathy is one of the major causes of end-stage renal disease. As impaired fibrinolysis can...
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From:Renal & Urology News (Vol. 15, Issue 2)PHOSPHATE AMOUNTS typically consumed in meals and snacks varies, but dialysis patients do not appear to adjust their phosphate binders to match the food phosphate content, a new study suggests. Deborah Zimmerman, MD,...
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From:PLoS ONE (Vol. 8, Issue 12) Peer-ReviewedAuthor(s): Nana Zhang 1, Maoqiang Zhuang 1, Aixia Ma 1, Guochang Wang 1, Ping Cheng 1, Yajun Yang 2,3, Xiaofeng Wang 2,3, Juan Zhang 3, Xingdong Chen 2,3, Ming Lu 1,2,3,* Introduction Epidemiological statistics...
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From:Journal of Diabetes Research (Vol. 2016) Peer-ReviewedThe increase in the prevalence of diabetes mellitus (DM) and the secondary kidney damage produces diabetic nephropathy (DN). Early nephropathy is defined as the presence of microalbuminuria (30-300 mg/day), including...
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From:Journal of Diabetes Research (Vol. 2016) Peer-ReviewedObjective. To investigate the expression of miR-192 and its significance in diabetic nephropathy (DN) patients. Methods. 464 patients with type 2 diabetes mellitus (T2DM) were divided into normal albuminuria group (NA,...
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From:Pharmacognosy Research (Vol. 9, Issue 4) Peer-ReviewedByline: Fariba. Azarkish, Kobra. Hashemi, Ardashir. Talebi, Mohammad. Kamalinejad, Nepton. Soltani, Nima. Pouladian Background: Our previous study showed antidiabetic effect of aqueous extract of Solanum nigrum Linn...
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From:Annals of African Medicine (Vol. 16, Issue 3) Peer-ReviewedByline: Zeba. Siddiqi, Ritu. Karoli, Anupama. Kaul, Jalees. Fatima, Shishir. Varshney, Mohd. Beg Introduction: Diabetes mellitus (DM) is a major cause of concern because of its increasing prevalence rate and related...
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From:BioMed Research InternationalPeer-ReviewedThe aim of our work was to evaluate, in an animal model of severe diabetes mellitus, the effect of mesenchymal stem cells (MSCs) administration on diabetic nephropathy (DN) progression. After diabetes induction, one...
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From:BioMed Research InternationalPeer-ReviewedTGF-[[beta].sub.1] has been recognized as a key mediator in DN. This study aimed to observe the effects of low-protein diets supplemented with ketoacid on mRNA and protein expression of TGF-[beta] and T[beta]RI and t...
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From:Oxidative Medicine and Cellular Longevity (Vol. 2016) Peer-ReviewedIn chronic kidney disease inflammatory processes and stimulation of immune cells result in overproduction of free radicals. In combination with a reduced antioxidant capacity this causes oxidative stress. This review...
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From:Nephrology Nursing Journal (Vol. 40, Issue 2) Peer-ReviewedThe study was to examine the effects of a six-month educational program aiming acquisition of self-management skills on patients with diabetic nephropathy, One-group, pre- and post-test design was performed....