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• Antibiotics and OC effectiveness

  Authors:Keri C. Anderson and Siam O. LieuFrom:JAAPA-Journal of the American Academy of Physicians Assistants (Vol. 26, Issue 1) Peer-Reviewed

  Jan. 2013874 words Article 1800L* WHAT IS THE ISSUE? Clinicians are often asked to advise patients who concomitantly use oral contraceptives (OCs) and antibiotics on possible risks of birth control failure. Even though both OCs and antibiotics have...

• Effect of estradiol, vitamin A, E and selenium treatment with varying sexual rest period on recovery rate in cross-bred cows with chronic endometritis

  Authors:Dipyaman Sengupta and Pramod R. NandiFrom:Veterinary World (Vol. 6, Issue 2)

  Feb. 20132,284 words Report 1610LAim: This work was done to study the effect of vitamin A, E and Se with varying sexual rest period in cross-bred cows with chronic endometritis. Materials and Methods: Cross-bred cows (n = 396) from different...

• Does first line antiretroviral therapy increase the prevalence of cardiovascular risk factors in Indian patients?: A cross sectional study

  Authors:Rab Carey, P. Rupali, O. Abraham, and D. KattulaFrom:Journal of Postgraduate Medicine (Vol. 59, Issue 4) Peer-Reviewed

  October-December 20132,490 words Report 1490LByline: RAB. Carey, P. Rupali, O. Abraham, D. Kattula Context: Antiretroviral therapy (ART) is associated with a myriad of metabolic complications which are potential cardiovascular risk factors. Early detection of...

• Highlights from the latest articles in nanoassemblies and nanobiopsy

  Authors:Bruno Teste and Stephanie DescroixFrom:Nanomedicine (Vol. 9, Issue 10) Peer-Reviewed

  July 20142,006 words Article 1300LAuthor(s): Bruno Teste aff1 , Stéphanie Descroix [*] aff2 Biologically inspired nanostructures dedicated to Alzheimer's disease treatment Evaluation of: Song Q, Huang M, Yao L et al. Lipoprotein-based...

• Drug interaction as cause of spontaneously resolving epidural spinal hematoma on warfarin therapy

  Authors:Amitabh Sagar and K. HassanFrom:Journal of Neurosciences in Rural Practice (Vol. 1, Issue 1) Peer-Reviewed

  January-June 20102,115 words Report 1470LByline: Amitabh. Sagar, K. Hassan We present a case of a 42-year-old male, an old case of deep vein thrombosis on warfarin and other drugs like quetiapine, aspirin, diclofenac sodium, fenofibrate, atorvastatin,...

• Cisplatin/various drugs interaction: renal impairment: case report

  From:Reactions Weekly (Issue 1283)

  Jan. 9, 2010189 words Brief article, Case ... [X] [S] A 63-year-old man with hypertension and type 2 diabetes mellitus started treatment with cisplatin [dosage not stated] and gemcitabine for high-grade urethral cancer. He was also started on...

• Glimepiride/voriconazole interaction: interaction (first report) leading to hypoglycaemia in an elderly patient: case report

  From:Reactions Weekly (Issue 1310)

  July 17, 2010389 words Brief article, Case ... 1090L[S] A 69-year-old man developed life-threatening hypoglycaemia following concomitant administration of oral voriconazole [Vfend] for empirical treatment of a fungal infection and oral glimepiride [Amaryl] for...

• Effective Integration of Systems Biology, Biomarkers, Biosimulation, and Modeling in Streamlining Drug Development

  Authors:Rajesh Krishna, Hans Guenter Schaefer, and Ole J. BjerrumFrom:Journal of Clinical Pharmacology (Vol. 47, Issue 6) Peer-Reviewed

  June 20073,806 words Conference notes 1640LThe European Federation of Pharmaceutical Sciences (EUFEPS) has long established itself as a leader in the field of interdisciplinary meetings to discuss issues that face drug development. Its everpopular and...

• Itraconazole, gemfibrozil, loperamide: interaction: increased plasma concentrations of loperamide

  From:Clin Alert (Vol. 44, Issue 13)

  July 15, 2006279 words Brief article 1360LNo. 179 A prospective, randomized, 4-phase crossover study of 12 healthy adults (6 male) was conducted to investigate the effects of itraconazole, gemfibrozil, and their combination on loperamide. Patients received...

• Drug-disease interactions: losartan effect is not downregulated by rheumatoid arthritis

  Authors:Noriko Daneshtalab, Richard Z. Lewanczuk, Anthony S. Russell, and Fakhreddin JamaliFrom:Journal of Clinical Pharmacology (Vol. 46, Issue 11) Peer-Reviewed

  Nov. 20064,587 words Article 1760LInflammatory conditions, such as rheumatoid arthritis, reduce response to calcium channel and [beta]-adrenergic antagonists but not the angiotensin II type 1 receptor ([AT.sub.1]R) antagonist valsartan. Inflammation...

• Choose the best sunscreen for you. (The Diabetes Advisor)

  Author:Shauna S. RobertsFrom:Diabetes Forecast (Vol. 56, Issue 6)

  June 2003553 words Article SUNSCREENS can help protect your skin from the intense summer sun--but only if you choose wisely and use them correctly. Protecting skin from sun pays off: * You avoid painful sunburns. * You avoid problems...

• Interaction between corticosteroid and beta-agonist drugs: biochemical and cardiovascular effects in normal subjects

  Authors:D. Robin Taylor, Gerard T. Wilkins, G. Peter Herbison, and Erin M. FlanneryFrom:Chest (Vol. 102, Issue 2) Peer-Reviewed

  Aug. 19923,482 words Article The aim of this study was to investigate whether the administration of prednisone potentiates any of the acute biochemical and cardiovascular effects of high-dose inhaled [beta]-agonist drugs. These agents are known to...

• No pharmacokinetic interaction found between lamotrigine and olanzapine

  Author:Y.W. Francis LamFrom:The Brown University Psychopharmacology Update (Vol. 17, Issue 7)

  July 2006628 words Article 1540LIn addition to their primary use in the management of seizure disorders, antiepileptic drugs such as lamotrigine (Lamictal) are increasingly used for treating different non-neurological disorders such as depression and...

• Comparison between hydrochlorthiazide and diltiazem added on to angiotensin receptor blocker in reducing proteinuria in patients with chronic kidney disease

  Authors:Dana A. Sharif, Kawa H. Amin, Bushra M. Ali, and Khalil Y. KhalafFrom:Indian Journal of Scientific ResearchPeer-Reviewed

  Dec. 20152,041 words Report 1450LProteinuria is an early marker of chronic kidney disease. The severity of proteinuria is an indicator of progressive loss of renal function especially when it co-exits with hypertension. Therefore, many drugs are used...

• Systematic Analysis of Cell Cycle Effects of Common Drugs Leads to the Discovery of a Suppressive Interaction between Gemfibrozil and Fluoxetine

  Authors:Scott A. Hoose, Camille Duran, Indranil Malik, Shabnam Eslamfam, Samantha C. Shasserre, S. Sabina Downing, et al.From:PLoS ONE (Vol. 7, Issue 5) Peer-Reviewed

  May 2, 20125,027 words Article 1410LAuthor(s): Scott A. Hoose 1 , Camille Duran 1 , Indranil Malik 1 , Shabnam Eslamfam 1 , Samantha C. Shasserre 1 , S. Sabina Downing 1 , Evelyn M. Hoover 1 , Katherine E. Dowd 1 , Roger Smith 2 , Michael Polymenis 1 , *...

• Cardioprotective effect of pioglitazone in diabetic and non-diabetic rats subjected to acute myocardial infarction involves suppression of AGE-RAGE axis and inhibition of apoptosis

  Authors:Dina M. Khodeer, Sawsan A. Zaitone, Noha E. Farag, and Yasser M. MoustafaFrom:Canadian Journal of Physiology and Pharmacology (Vol. 94, Issue 5) Peer-Reviewed

  May 20168,223 words Report 1530LInsulin resistance increases risk of cardiovascular diseases. This work investigated the protective effect of pioglitazone on myocardial infarction (MI) in non-diabetic and diabetic rats, focusing on its role on...

• Assessment of the potential for displacement interactions with sugammadex: a pharmacokinetic-pharmacodynamic modelling approach

  Authors:Alex Zwiers, Michiel van den Heuvel, Jean Smeets, and Samantha RutherfordFrom:Clinical Drug Investigation (Vol. 31, Issue 2) Peer-Reviewed

  Feb. 20114,395 words Clinical report 1670LBackground: Sugammadex is a g-cyclodextrin that binds with high affinity to the neuromuscular blocking agents (NMBAs) rocuronium (bromide) and vecuronium (bromide) by encapsulation. Cyclodextrins are known to form...

• Magnesium valproate-induced pedal edema on chronic therapy: A rare adverse drug reaction

  Authors:Himani Prajapati, Dinesh Kansal, and Rajan NegiFrom:Indian Journal of Pharmacology (Vol. 49, Issue 5) Peer-Reviewed

  September-October 2017968 words Report 1450LByline: Himani. Prajapati, Dinesh. Kansal, Rajan. Negi Valproate-related pedal edema is usually regarded as a problem occurring after long-term administration of valproate. Valproate has been a drug of choice for the...

• Prevalence of clinically manifested drug interactions in hospitalized patients: A systematic review and meta-analysis

  Authors:Tamara Natasha Gonzaga de Andrade Santos, Givalda Mendonca da Cruz Macieira, Barbara Manuella Cardoso Sodre Alves, Thelma Onozato, Geovanna Cunha Cardoso, Monica Thais Ferreira Nascimento, et al.From:PLoS ONE (Vol. 15, Issue 7) Peer-Reviewed

  July 1, 20205,327 words Report 1470LAuthor(s): Tâmara Natasha Gonzaga de Andrade Santos 1, Givalda Mendonça da Cruz Macieira 1, Bárbara Manuella Cardoso Sodré Alves 1, Thelma Onozato 1, Geovanna Cunha Cardoso 1, Mônica Thaís Ferreira Nascimento 1, Paulo...

• Aldehyde dehydrogenase 2*2 knock-in mice show increased reactive oxygen species production in response to cisplatin treatment

  Authors:Jeewon Kim, Che-Hong Chen, Jieying Yang, and Daria Mochly-RosenFrom:Journal of Biomedical Science (Vol. 24, Issue 1) Peer-Reviewed

  May 22, 20174,510 words Report 1500LBackground The aldehyde dehydrogenase (ALDH) enzyme family metabolizes and detoxifies both exogenous and endogenous aldehydes. Since chemotherapeutic agents, such as cisplatin, generate cytotoxic aldehydes and...