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From:Molecular Diagnosis & Therapy (Vol. 13, Issue 4) Peer-ReviewedEfavirenz: Hyperhidrosis in a Patient with CYP2D6 Mutation: Case Report A 44-year-old man experienced hyperhidrosis while receiving efavirenz for HIV infection; he was subsequently found have a cytochrome P450 (CYP)...
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From:South African Journal of Communication Disorders (Vol. 67, Issue 1) Peer-ReviewedBackground Recent estimates reveal that there are approximately 280 000 children between the ages of birth and 14 years who are living with the human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome...
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From:PLoS ONE (Vol. 15, Issue 3) Peer-ReviewedBackground The presence of drug resistance mutations (DRMs) against antiretroviral agents is one of the main concerns in the clinical management of individuals with human immunodeficiency virus-1 (HIV-1) infection,...
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From:The Brazilian Journal of Infectious Diseases (Vol. 23, Issue 4) Peer-ReviewedAbacavir can cause a multi-systemic hypersensitivity reaction (HSR) in 5-8% of the patients, which is related to HLA-B*57-01 allele. In Brazil, the HLA-B*57-01 screening test became available only in March 2018, several...
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From:Indian Journal of Sexually Transmitted Diseases and AIDS (Vol. 42, Issue 1) Peer-ReviewedByline: Atul. Patel, Ketan. Patel, Sanjay. Pujari, Jagdish. Patel, Ambuj. Kumar Background: Dolutegravir (DTG) is widely used for the management of naïve and treatment-experienced HIV-infected patients. Low-level...
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From:Journal of the International AIDS Society (Vol. 23, Issue 4) Peer-ReviewedIntroduction: Prior to the availability of rilpivirine (RPV), patients who could not tolerate efavirenz and nevirapine (NVP) were treated with protease inhibitor (PI)-based antiretroviral therapy (ART). Dyslipidaemia and...
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From:Journal of the International AIDS Society (Vol. 25, Issue 1) Peer-ReviewedIntroduction: Efavirenz (EFV) is commonly used for first-line antiretroviral therapy in children and adolescents with HIV, but is associated with neuropsychiatric and metabolic side effects. Rilpivirine (RPV) is better...
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From:Reactions Weekly (Issue 1234)[S] A 62-year-old, HIV-positive man developed fatal lactic acidosis during treatment with didanosine, efavirenz and stavudine. The man had a history of ethanol-induced liver cirrhosis and renal impairment. He...
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From:PLoS ONE (Vol. 7, Issue 9) Peer-ReviewedAuthor(s): Samir K. Gupta 1 , * , Changyu Shen 2 , Sharon M. Moe 3 , Lisa M. Kamendulis 4 , Mitchell Goldman 1 , Michael P. Dubé 5 Introduction It has been suggested that both HIV infection itself and the...
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From:KLIMIK Journal (Vol. 32, Issue 2) Peer-ReviewedInfections are the most common causes of fever of unknown origin (FUO). Both human immunodeficiency virus (HIV) itself and its concomitant opportunistic infections cause FUO. Clinically, the symptoms and findings are...
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From:PLoS ONE (Vol. 14, Issue 11) Peer-ReviewedBackground Roll-out of Integrase Strand Transfer Inhibitors (INSTIs) such as dolutegravir for HIV combination antiretroviral therapy (cART) in sub-Saharan Africa necessitates the development of affordable HIV drug...
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From:Journal of the International AIDS Society (Vol. 23, Issue 4) Peer-ReviewedIntroduction: The World Health Organisation recommends to Treat All people with HIV, irrespective of CD4 count. However, people with CD4 counts >500 cells/[micro]L may be asymptomatic and therefore less motivated to...
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From:Journal of the International AIDS Society (Vol. 23, Issue 1) Peer-ReviewedIntroduction: Tuberculosis (TB) is a leading cause of mortality among people living with HIV (PLHIV). An invigorated global END TB Strategy seeks to increase efforts in scaling up TB preventive therapy (TPT) as a central...
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From:Diabetology & Metabolic Syndrome (Vol. 13, Issue 1) Peer-ReviewedIntroduction Since the development of antiretroviral therapy (ART) with TDF plus 3TC plus EFV, this specific regimen has not been studied enough with long-term lipid and uric acid monitoring. Methods A prospective...
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From:Journal of Toxicology (Vol. 2021) Peer-ReviewedAcquired immune deficiency syndrome (AIDS) is a major public health problem affecting several countries with predominance in black Africa. Faced with therapeutic failure caused by resistance and supply disruptions,...
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From:Journal of the International AIDS Society (Vol. 23, Issue 5) Peer-ReviewedKeywords: HIV; ART; differentiated service delivery; stable; COVID-19; pandemic; emergency response; supply chain; Dolutegravir; stock out; severe acute respiratory syndrome coronavirus 2; SARS-CoV-2; multi-month...
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From:Indian Journal of Drugs in Dermatology (Vol. 3, Issue 1) Peer-ReviewedByline: Bhavana. Doshi, B. Manjunathswamy An 18-year-old male came with complaints of red rash over the trunk, back, and arms associated with itching for 3 days. He stated that these lesions had appeared first over...
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From:PLoS ONE (Vol. 15, Issue 4) Peer-ReviewedBackground Despite the World Health Organization listing methadone as an essential medication, effective dose selection is challenging, especially in racial and ethnic minority populations. Subtherapeutic doses can...
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From:Journal of the International AIDS Society (Vol. 22, Issue 10) Peer-ReviewedIntroduction: Differentiated models of care that include referral of antiretroviral treatment (ART) clients to adherence clubs are an important strategy to help clinics manage increased number of clients living with HIV...
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From:Indian Journal of Dermatology (Vol. 66, Issue 6) Peer-ReviewedByline: Preema. Sinha, Afreen. Ayub, K. Priya, Manoj. Madakshira, M. Arjun, Varghese. Koshy Sir, Psoriasiform dermatitis comprises a group of disorders, which clinically and/or histologically simulates psoriasis and...