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    Academic Journals

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• Epidermal growth factor receptor gene expression evaluation in colorectal cancer patients

  Authors:G. Motalleb, E. Pourrahmat, S. Najafi, A. Rashki, A. Moghadam, M. Mazaheri, et al.From:Indian Journal of Cancer (Vol. 51, Issue 3) Peer-Reviewed

  July-September 20142,991 words Report 1910LByline: G. Motalleb, E. Pourrahmat, S. Najafi, A. Rashki, A. Moghadam, M. Mazaheri, M. Jahantigh, K. Sabagh, N. Sanadgol, S. Najafi, R. Talaee Background: Colorectal cancer is one of the most common causes of death...

• Personalized treatment of early-stage non-small-cell lung cancer: the challenging role of EGFR inhibitors

  Authors:Mariacarmela Santarpia, Giuseppe Altavilla, Vincenzo Pitini, and Rafael RosellFrom:Future Oncology (Vol. 11, Issue 8) Peer-Reviewed

  Apr. 201511,158 words Report 1850LAuthor(s): Mariacarmela Santarpia [*] aff1 , Giuseppe Altavilla aff1 , Vincenzo Pitini aff1 , Rafael Rosell aff2 aff3 aff4 KEYWORDS adjuvant therapy; EGFR mutations; EGF receptor inhibitors; non-small-cell lung...

• EGFR mutations in lung cancer: from tissue testing to liquid biopsy

  Authors:Francesca Fenizia, Antonella De Luca, Raffaella Pasquale, Alessandra Sacco, Laura Forgione, Matilde Lambiase, et al.From:Future Oncology (Vol. 11, Issue 11) Peer-Reviewed

  June 20159,703 words Report 1950LAuthor(s): Francesca Fenizia aff1 , Antonella De Luca aff2 , Raffaella Pasquale aff1 , Alessandra Sacco aff1 , Laura Forgione aff1 , Matilde Lambiase aff1 , Alessia Iannaccone aff1 , Nicoletta Chicchinelli aff2 , Renato...

• Prognostic significance of the EGFR pathway in nasopharyngeal carcinoma: a systematic review and meta-analysis

  Authors:Marc L Ooft, Weibel W Braunius, Paulien Heus, Inge Stegeman, Paul J van Diest, Wilko Grolman, et al.From:Biomarkers in Medicine (Vol. 9, Issue 10) Peer-Reviewed

  Oct. 20157,262 words Report 1480LAuthor(s): Marc L Ooft [*] aff1 , Weibel W Braunius aff2 , Paulien Heus aff3 , Inge Stegeman aff2 , Paul J van Diest aff1 , Wilko Grolman aff2 , Charlotte I Zuur aff4 , Stefan M Willems aff1 Keywords: cancer;...

• Coamplification with colocalization of the human epidermal growth factor receptor 2 and centromeric-17 signals on fluorescence in situ hybridization in invasive breast carcinoma: An exceedingly rare finding

  Authors:T. Pai, O. Shetty, A. Patil, T. Shet, and S. DesaiFrom:Journal of Postgraduate Medicine (Vol. 62, Issue 3) Peer-Reviewed

  July-September 2016710 words Article 1690LByline: T. Pai, O. Shetty, A. Patil, T. Shet, S. Desai Human epidermal growth factor receptor 2 (HER2) gene amplification is a well-established prognostic and predictive marker in breast cancer. Introduction of the...

• Epidermal growth factor receptor expression in gastric tumors and its relationship with the germline polymorphisms − 216 G>T, −191 C>A, (CA) n IVS1, and R521K

  Authors:JH Torres-Jasso, AR Bustos-Carpinteyro, JR Garcia-Gonzalez, J. Peregrina-Sandoval, JA Cruz-Ramos, E. Santiago-Luna, et al.From:Indian Journal of Cancer (Vol. 53, Issue 3) Peer-Reviewed

  July-September 20162,764 words Report 1450LByline: JH. Torres-Jasso, AR. Bustos-Carpinteyro, JR. Garcia-Gonzalez, J. Peregrina-Sandoval, JA. Cruz-Ramos, E. Santiago-Luna, JY. Sanchez-Lopez BACKGROUND: Gastric cancer (GC) is the third worldwide leading cause...

• Analytic and Clinical Validation of an Ultrasensitive, Quantitative Polymerase Chain Reaction Assay for EGFR Mutation Analysis With Circulating Tumor DNA

  Authors:Xiaowei Wang, Yunhua Gao, Bei Wang, Zhenrong Zhang, Chaoyang Liang, Hongxiang Feng, et al.From:Archives of Pathology & Laboratory Medicine (Vol. 141, Issue 7) Peer-Reviewed

  July 20175,329 words Report 2300LContext.--The mutation analysis of epidermal growth factor receptor (EGFR) has become a common test to guide therapeutic decision making for lung cancer. Molecular testing with circulating tumor DNA in plasma allows...

• Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis

  Authors:Petrus R. de Jong, Naoki Takahashi, Alexandra R. Harris, Jihyung Lee, Samuel Bertin, James Jeffries, et al.From:Journal of Clinical Investigation (Vol. 124, Issue 9) Peer-Reviewed

  Sept. 20148,909 words Report 1370LThe intestinal epithelium has a high rate of turnover, and dysregulation of pathways that regulate regeneration can lead to tumor development; however, the negative regulators of oncogenic events in the intestinal...

• Bone metastases incidence and its correlation with hormonal and human epidermal growth factor receptor 2 neu receptors in breast cancer

  Authors:Ananya Pareek, O. Singh, Veenita Yogi, H. Ghori, Vivek Tiwari, and Pallavi RedhuFrom:Journal of Cancer Research and Therapeutics (Vol. 15, Issue 5) Peer-Reviewed

  July-September 20192,643 words Report 1650LByline: Ananya. Pareek, O. Singh, Veenita. Yogi, H. Ghori, Vivek. Tiwari, Pallavi. Redhu Aim: In this paper, we present a prospective observational study, which determines the incidence of bone metastases and its...

• The importance of brain metastasis in EGFR mutation positive NSCLC patients

  Authors:Vanita Noronha, Amit Joshi, Anant Gokarn, Vibhor Sharma, Vijay Patil, Amit Janu, et al.From:Chemotherapy Research and PracticePeer-Reviewed

  Annual 20142,714 words Clinical report 1480LIntroduction. Brain metastasis is a poor prognostic marker in lung cancer. However it is not known whether amongst patients with EGFR mutation those with brain metastases have a worse outcome. Methods. We compared the...

• In Vitro Drug Sensitivity Tests to Predict Molecular Target Drug Responses in Surgically Resected Lung Cancer

  Authors:Ryohei Miyazaki, Takashi Anayama, Kentaro Hirohashi, Hironobu Okada, Motohiko Kume, and Kazumasa OrihashiFrom:PLoS ONE (Vol. 11, Issue 4) Peer-Reviewed

  Apr. 12, 20165,478 words Report 1530LBackground Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) and anaplastic lymphoma kinase (ALK) inhibitors have dramatically changed the strategy of medical treatment of lung cancer. Patients...

• Selective Killing Effects of Cold Atmospheric Pressure Plasma with NO Induced Dysfunction of Epidermal Growth Factor Receptor in Oral Squamous Cell Carcinoma

  Authors:Jung-Hwan Lee, Ji-Yeon Om, Yong-Hee Kim, Kwang-Mahn Kim, Eun-Ha Choi, and Kyoung-Nam KimFrom:PLoS ONE (Vol. 11, Issue 2) Peer-Reviewed

  Feb. 26, 20168,099 words Report 1550LThe aim of this study is to investigate the effects of cold atmospheric pressure plasma (CAP)-induced radicals on the epidermal growth factor receptor (EGFR), which is overexpressed by oral squamous cell carcinoma, to...

• Epidermal growth factor receptor-targeted sonoporation with microbubbles enhances therapeutic efficacy in a squamous cell carcinoma model

  Authors:Fumika Hirabayashi, Kenjiro Iwanaga, Toshinori Okinaga, Osamu Takahashi, Wataru Ariyoshi, Ryo Suzuki, et al.From:PLoS ONE (Vol. 12, Issue 9) Peer-Reviewed

  Sept. 22, 20174,956 words Report 1320LSonoporation is a drug and gene delivery system using ultrasonication that allows the intracellular delivery of foreign molecules that cannot enter cells under normal conditions. We previously reported that sonoporation...

• The proneural wave in the Drosophila optic lobe is driven by an excitable reaction-diffusion mechanism

  Authors:David J Jorg, Elizabeth E Caygill, Anna E Hakes, Esteban G Contreras, Andrea H Brand, and Benjamin D SimonsFrom:eLife (Vol. 8) Peer-Reviewed

  Feb. 22, 201912,913 words Report 1500LIn living organisms, self-organised waves of signalling activity propagate spatiotemporal information within tissues. During the development of the largest component of the visual processing centre of the Drosophila...

• Clinicopathological features of invasive lobular carcinoma of the breast: A nationwide multicenter study in China

  Authors:M. Zhu, X. Yu, X. He, W. Feng, J. Fan, J. Li, et al.From:Journal of Cancer Research and Therapeutics (Vol. 11, Issue 5) Peer-Reviewed

  Aug. 20153,799 words Report 1590LByline: M. Zhu, X. Yu, X. He, W. Feng, J. Fan, J. Li, F. Xu, Z. Tang, B. Zhang, Y. Qiao, S. Zheng, H. Yang Objective: To analyze the clinicopathological features of invasive lobular carcinoma (ILC) and compare them...

• Optimization of Substituted 6-Salicyl-4-Anilinoquinazoline Derivatives as Dual EGFR/HER2 Tyrosine Kinase Inhibitors

  Authors:Dong-Dong Li, Ya-Juan Qin, Jian Sun, Jing-Ran Li, Fei Fang, Qian-Ru Du, et al.From:PLoS ONE (Vol. 8, Issue 8) Peer-Reviewed

  Aug. 1, 20137,851 words Report 1520LAuthor(s): Dong-Dong Li 1, Ya-Juan Qin 1, Jian Sun 1, Jing-Ran Li 1, Fei Fang 1, Qian-Ru Du 1, Yong Qian 1, Hai-Bin Gong 2,*, Hai-Liang Zhu 1,* Introduction The epidermal growth factor receptor (EGFR) family of...

• Do oncogenic drivers exist in squamous cell carcinoma of the lung?

  Authors:Liza C. Villaruz, Timothy F. Burns, and Mark A. SocinskiFrom:Oncology (Vol. 27, Issue 9) Peer-Reviewed

  Sept. 20131,376 words Report 2230LThere has been a tremendous paradigm shift in the evaluation and treatment of lung cancer over the last decade, with the discovery that patients who have adenocarcinoma of the lung with activating mutations in the EGFR...

• In search of rigorous data on how to palliate the EGFR inhibitor-induced rash

  Author:Aminah JatoiFrom:Oncology (Vol. 23, Issue 2) Peer-Reviewed

  Feb. 2009881 words Report 1830LEpidermal growth factor receptor (EGFR) inhibitors have emerged as important drugs in cancer therapy, providing a proven survival advantage for some patients with non-small-cell lung cancer, colorectal cancer, head and...

• Interference with EGFR signaling: paradigm for improving radiation response in cancer treatment

  Authors:David Raben, Cataldo Bianco, Barb Helfrich, Elaine Weng, Fortunato Ciardiello, and Paul HarariFrom:Expert Review of Anticancer Therapy (Vol. 2, Issue 4) Peer-Reviewed

  Aug. 1, 20026,751 words Report 1500LThe introduction of biologically active agents that interfere with the epidermal growth factor receptor (EGFR) provides a promising opportunity to improve cancer treatment outcomes. Several EGFR-selective agents, such...

• Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

  Authors:Guillaume Bollee, Martin Flamant, Sandra Schordan, Cecile Fligny, Elisabeth Rumpel, Marine Milon, et al.From:Nature Medicine (Vol. 17, Issue 10) Peer-Reviewed

  Oct. 20117,975 words Report 1430LRapidly progressive glomerulonephritis (RPGN) is a life-threatening clinical syndrome and a morphological manifestation of severe glomerular injury that is marked by a proliferative histological pattern ('crescents')...