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Academic Journals
- 1,193
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From:Journal of Pediatric Neurosciences (Vol. 8, Issue 1) Peer-ReviewedByline: George. Alexiou, Maria. Moschovi, Kalliopi. Stefanaki, Dimitrios. Panagopoulos, Maria. Tsotra, George. Siozos, George. Sfakianos, Neofytos. Prodromou Background: Intracranial ependymomas are the third most...
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From:BioDrugs (Vol. 25, Issue 3) Peer-ReviewedErlotinib is a low molecular weight, orally active, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. Inhibition of EGFR tyrosine kinase results in the disruption of processes involved in cancer growth...
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From:Expert Review of Molecular Diagnostics (Vol. 7, Issue 6) Peer-ReviewedAuthor(s): Tae-You Kim 1 , Sae-Won Han 2 , Yung-Jue Bang [[dagger]] 3 Keywords: amplification; biomarker; EGFR; erlotinib; FISH; gefitinib; mutation; NSCLC EGF receptor (EGFR) is a member of the ErbB receptor...
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From:Family Practice News (Vol. 37, Issue 14)CHICAGO -- Tetracycline may reduce the severity of rashes associated with epidermal growth factor receptor inhibitors, such as gefitinib and cetuximab, but the antibiotic doesn't seem to prevent such rashes. More...
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From:Future Oncology (Vol. 2, Issue 6) Peer-ReviewedAuthor(s): Amber Yasmeen 1 , Tarek A Bismar 2 , Ala-Eddin Al Moustafa [[dagger]] 3 Keywords: epithelial-caderin-catenin complex; epithelial cancer cells; ErbB receptors Proper regulation of a cell depends on...
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From:PLoS ONE (Vol. 7, Issue 1) Peer-Reviewed
TWIST1 a New Determinant of Epithelial to Mesenchymal Transition in EGFR Mutated Lung Adenocarcinoma
Author(s): Karine Pallier 1 , 2 , Anatole Cessot 1 , 2 , Jean-Francois Côté 3 , Pierre-Alexandre Just 2 , 4 , Aurélie Cazes 2 , 4 , Elizabeth Fabre 1 , Claire Danel 5 , Marc Riquet 2 , 6 , Mojgan Devouassoux-Shisheboran... -
From:PLoS ONE (Vol. 7, Issue 6) Peer-ReviewedAuthor(s): Saghir Akhtar * , Mariam H. M. Yousif, Bindu Chandrasekhar, Ibrahim F. Benter Introduction Diabetes significantly increases the risk of cardiovascular disease by 3- to 8-fold [1]. Current diabetic...
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From:PLoS ONE (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Benjamin B. Parrott 1 , Alicia Hudson 2 , Regina Brady 3 , Cordula Schulz 2 , * Introduction Adult stem cells self-renew and give rise to differentiating daughters that maintain specific tissues...
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From:PLoS ONE (Vol. 9, Issue 1) Peer-ReviewedAuthor(s): Ian F. G. King *, Mark Eddison **b, Karla R. Kaun **c, Ulrike Heberlein **b Introduction Though alcohol dependence is highly influenced by genetics, it has proven difficult to conclusively identify...
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From:PLoS ONE (Vol. 9, Issue 3) Peer-ReviewedAuthor(s): Tao Pan 1,2, Junfeng Sun 3, Jiyi Hu 1, Yiwang Hu 1, Jun Zhou 1, Zhigang Chen 1, Dong Xu 2, Wenhong Xu 2, Shu Zheng 1, Suzhan Zhang 1,* Introduction Colorectal cancer (CRC) remains to be the third most...
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From:Archives of Pathology & Laboratory Medicine (Vol. 140, Issue 8) Peer-ReviewedContext.--The pioneering works on molecular classification (MC) by Perou and Sorlie et al in the early 2000s using global gene expression profiling identified 5 intrinsic subtypes of invasive breast cancers (IBCs):...
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From:Archives of Pathology & Laboratory Medicine (Vol. 140, Issue 3) Peer-ReviewedContext: Birt-Hogg-Dube; syndrome (BHDS) is an inherited disorder caused by genetic mutations of folliculin (FLCN). Individuals with BHDS have multiple pulmonary cysts and skin papules, and they are at high risk for...
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From:Lung India (Vol. 35, Issue 1) Peer-ReviewedByline: Amit. Joshi, Vijay. Patil, Vanita. Noronha, Anuradha. Chougule, Atanu. Bhattacharjee, Rajiv. Kumar, Supriya. Goud, Sucheta. More, Anant. Ramaswamy, Ashay. Karpe, Nikhil. Pande, Arun. Chandrasekharan, Alok. Goel,...
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From:Indian Journal of Cancer (Vol. 54, Issue 5) Peer-ReviewedByline: Suresh. Advani, Hemant. Malhotra, Raju. Chacko, Maheboob. Basade, Pavithran. Keechilat, P. Mahapatra, Chanchal. Goswami, T. Sahoo, Chirag. Shah Advanced nonsmall cell lung cancer (NSCLC) treatment is...
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From:Archives of Pathology & Laboratory Medicine (Vol. 137, Issue 12) Peer-ReviewedContext.--The diagnosis and treatment of non-small cell lung cancer have changed dramatically in the past few years. The discovery of activating mutations in the tyrosine kinase domain of the epidermal growth factor...
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From:Diabetes (Vol. 45, Issue 11) Peer-Reviewed3T3-L1 adipocytes represent an established physiological model for studying glucose uptake and storage. Overexpression of epidermal growth factor (EGF) receptors in these cells (20O,000-250,000 receptors per cell)...
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From:PLoS ONE (Vol. 15, Issue 1) Peer-ReviewedThe epidermal growth factor receptor inhibitor cetuximab is the only oncogene-targeted agent that has been FDA approved for the treatment of head and neck squamous cell carcinoma (HNSCC). Currently, there are no...
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From:PLoS ONE (Vol. 14, Issue 11) Peer-ReviewedHuman infections due to the monkey malaria parasite Plasmodium knowlesi are increasingly being reported from Malaysia. The parasite causes high parasitaemia, severe and fatal malaria in humans thus there is a need for...
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From:Journal of Clinical Investigation (Vol. 123, Issue 4) Peer-ReviewedMolecular mechanisms specific to colitis-associated cancers have been poorly characterized. Using comparative whole-genome expression profiling, we observed differential expression of epiregulin (EREG) in mouse models...
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From:Journal of Experimental & Clinical Cancer Research (Vol. 39, Issue 1) Peer-ReviewedBackground Type 1 and 2 diabetes confer an increased risk of pancreatic cancer (PaC) of similar magnitude, suggesting a common mechanism. The recent finding that PaC incidence increases linearly with increasing fasting...