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    Academic Journals

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• Advisor forum: these are letters from practitioners around the country who want to share their clinical problems and successes, observations, and pearls with their colleagues. Responding consultants are identified below. We invite you to participate

  From:Clinical Advisor (Vol. 14, Issue 11)

  Nov. 20113,413 words Article 1310LCONSULTATIONS TREATING ELEVATED TRIGLYCERIDES If triglycerides are a more significant indicator of cardiovascular disease (CVD) risk in women than in men, is it appropriate to treat even if LDL is normal? If so,...

• N-3 Poly-Unsaturated Fatty Acids Shift Estrogen Signaling to Inhibit Human Breast Cancer Cell Growth

  Authors:WenQing Cao, ZhiFan Ma, Mark M. Rasenick, ShuYan Yeh, and JiangZhou YuFrom:PLoS ONE (Vol. 7, Issue 12) Peer-Reviewed

  Dec. 28, 20128,235 words Article 1440LAlthough evidence has shown the regulating effect of n-3 poly-unsaturated fatty acid (n-3 PUFA) on cell signaling transduction, it remains unknown whether n-3 PUFA treatment modulates estrogen signaling. The current...

• Omega-3 augmentation of citalopram

  From:The Brown University Psychopharmacology Update (Vol. 23, Issue 4)

  Apr. 2012300 words Brief article 1710LAugmentation of citalopram (Celexa) with omega-3 fatty acids led to significantly greater reduction in depressive symptoms in patients with major depressive disorder (MDD) compared with citalopram alone, according to a...

• A More Desirable Balanced Polyunsaturated Fatty Acid Composition Achieved by Heterologous Expression of [DELTA]15/[DELTA]4 Desaturases in Mammalian Cells

  Authors:Guiming Zhu, Qin Ou, Tao Zhang, Xudong Jiang, Guozhi Sun, Ning Zhang, et al.From:PLoS ONE (Vol. 8, Issue 12) Peer-Reviewed

  Dec. 31, 20134,949 words Article 1540LArachidonic (ARA), eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids are the most biologically active polyunsaturated fatty acids, but their biosyntheses in mammals are very limited. The biosynthesis of DHA is the...

• 13A Vitamins/minerals/supplements

  From:MPR Hematology and Oncology Edition (Vol. 5, Issue 2)

  Summer 2012769 words Article 790LANIMI-3 pbm Rx Folic acid 1mg, pyridoxine 12.5mg, Vit. [B.sub.12] 500mcg, omega-3 acids 500mg, docosahexaenoic acid 350mg, eicosapentaenoic acid 35mg; caps. Indications: Nutritional support. Folic acid...

• Circulating Docosahexaenoic Acid Levels Are Associated with Fetal Insulin Sensitivity

  Authors:Jin-Ping Zhao, Emile Levy, William D. Fraser, Pierre Julien, Edgard Delvin, Alain Montoudis, et al.From:PLoS ONE (Vol. 9, Issue 1) Peer-Reviewed

  Jan. 13, 20145,114 words Article 1710LAuthor(s): Jin-Ping Zhao 1, Emile Levy 2, William D. Fraser 1, Pierre Julien 3, Edgard Delvin 4, Alain Montoudis 2, Schohraya Spahis 2, Carole Garofalo 2, Anne Monique Nuyt 5, Zhong-Cheng Luo 1,6,* Introduction...

• Dysregulation in Plasma [omega]3 Fatty Acids Concentration and Serum Zinc in Heavy Alcohol-Drinking HCV Patients.

  Authors:Vatsalya Vatsalya, Ruchita Agrawal, Jane Frimodig, Shweta Srivastava, and Melanie L. SchwandtFrom:Advances in Virology (Vol. 2020) Peer-Reviewed

  June 30, 20205,758 words Article 1340LAlcohol use disorder (AUD) patients comorbid with hepatitis C virus (HCV) infection (HCV + AUD) could have progressively severe clinical sequels of liver injury and inflammation. Serum zinc and several polyunsaturated...

• Effects of diets enriched in saturated (Palmitic), monounsaturated (Oleic), or trans (Elaidic) fatty acids on insulin sensitivity and substrate Oxidation in healthy adults. (Clinical Care/Education/Nutrition)

  Authors:Jennifer C. Lovejoy, Steven R. Smith, Catherine M. Champagne, Marlene M. Most, Michael Lefevre, James P. DeLany, et al.From:Diabetes Care (Vol. 25, Issue 8) Peer-Reviewed

  Aug. 20024,901 words Article OBJECTIVE -- Diets high in total and saturated fat are associated with insulin resistance. This study examined the effects of feeding monounsaturated, saturated, and trans fatty acids on insulin action in healthy...

• Increased polyunsaturated fat intake could up risk of asthma: omega-3 to omega-6 ratio could be key

  Author:Sherry BoschertFrom:Family Practice News (Vol. 33, Issue 14)

  July 15, 2003551 words Article DENVER -- Consuming a high-fat diet early in childhood may raise the risk of asthma, Dr. Clare S. Murray reported at the annual meeting of the American Academy of Allergy, Asthma, and Immunology. Young atopic...

• A protective lipidomic biosignature associated with a balanced omega-6/omega-3 ratio in fat-1 transgenic mice

  Authors:Giuseppe Astarita, Jennifer H. McKenzie, Bin Wang, Katrin Strassburg, Angela Doneanu, Jay Johnson, et al.From:PLoS ONE (Vol. 9, Issue 4) Peer-Reviewed

  Apr. 20146,618 words Report 1530LA balanced omega-6/omega-3 polyunsaturated fatty acid (PUFA) ratio has been linked to health benefits and the prevention of many chronic diseases. Current dietary intervention studies with different sources of omega-3...

• Omega-3 Polyunsaturated Fatty Acids Suppress the Cystic Lesion Formation of Peritoneal Endometriosis in Transgenic Mouse Models

  Authors:Kensuke Tomio, Kei Kawana, Ayumi Taguchi, Yosuke Isobe, Ryo Iwamoto, Aki Yamashita, et al.From:PLoS ONE (Vol. 8, Issue 9) Peer-Reviewed

  Sept. 10, 20136,283 words Article 1400LOmega-3 polyunsaturated fatty acids (omega-3 PUFAs) play a role in controlling pathological inflammatory reactions. Endometriosis is characterized by the presence of endometrial tissue on the peritoneum and an...

• Effects of somatostatin, curcumin, and quercetin on the fatty acid profile of breast cancer cell membranes.

  Authors:Aysegul Hanikoglu, Ertan Kucuksayan, Ferhat Hanikoglu, Tomris Ozben, Georgia Menounou, Anna Sansone, et al.From:Canadian Journal of Physiology and Pharmacology (Vol. 98, Issue 3) Peer-Reviewed

  Mar. 20205,977 words Article 1530LBreast cancer is a worldwide commonly found malignancy in women and effective treatment is regarded as a huge clinical challenge even in the presence of several treatment options. Extensive literature is available...

• DHA Production in Escherichia coli by Expressing Reconstituted Key Genes of Polyketide Synthase Pathway from Marine Bacteria

  Authors:Yun-Feng Peng, Wen-Chao Chen, Kang Xiao, Lin Xu, Lian Wang, and Xia WanFrom:PLoS ONE (Vol. 11, Issue 9) Peer-Reviewed

  Sept. 20, 20165,269 words Article 1380LThe gene encoding phosphopantetheinyl transferase (PPTase), pfaE, a component of the polyketide synthase (PKS) pathway, is crucial for the production of docosahexaenoic acid (DHA, 22:6[omega]3), along with the other pfa...

• Complementary and alternative medical therapies for children with Attention-Deficit/ Hyperactivity Disorder (ADHD)

  Authors:Janice Pellow, Elizabeth M. Solomon, and Candice N. BarnardFrom:Alternative Medicine Review (Vol. 16, Issue 4) Peer-Reviewed

  Dec. 20118,796 words Article 2080LAbstract Attention-deficit/hyperactivity disorder (ADHD) is a commonly diagnosed childhood disorder characterized by impulsivity, inattention, and hyperactivity. ADHD affects up to 1 in 20 children in the United...

• Mechanisms involved in the differential reduction of omega-3 and omega-6 highly unsaturated fatty acids by structural heart disease resulting in "HUFA deficiency"

  Authors:Heinz Rupp, Thomas P. Rupp, Peter Alter, and Bernhard MaischFrom:Canadian Journal of Physiology and Pharmacology (Vol. 90, Issue 1) Peer-Reviewed

  Jan. 201210,833 words Report 1460LThe causes of reduced levels of omega-3 and omega-6 highly unsaturated fatty acids ("HUFA deficiency")in heart failure remain unresolved. HUFA profiles were examined in the serum of 331 patients with failing versus...

• Comprehensive Profiling of Plasma Fatty Acid Concentrations in Young Healthy Canadian Adults

  Authors:Salma A. Abdelmagid, Shannon E. Clarke, Daiva E. Nielsen, Alaa Badawi, Ahmed El-Sohemy, David M. Mutch, et al.From:PLoS ONE (Vol. 10, Issue 2) Peer-Reviewed

  Feb. 12, 20155,815 words Article 1510LCirculating fatty acids (FA) are associated with a multitude of chronic diseases. However, a major gap in establishing such relationships is the lack of accepted fatty acid reference ranges representing healthy...

• Proresolution Lipid Mediators in Multiple Sclerosis - Differential, Disease Severity-Dependent Synthesis - A Clinical Pilot Trial

  Authors:Harald Pruss, Berit Rosche, Aaron B. Sullivan, Benedikt Brommer, Oliver Wengert, Karsten Gronert, et al.From:PLoS ONE (Vol. 8, Issue 2) Peer-Reviewed

  Feb. 8, 20133,539 words Article 2040LBackground The severity and longevity of inflammation is controlled by endogenous counter-regulatory signals. Among them are long-chain polyunsaturated fatty acid (PUFA)-derived lipid mediators, which promote the...

• Transcriptome analysis of Chelidonium majus elaiosomes and seeds provide insights into fatty acid biosynthesis

  Authors:Jiayue Wu, Linlin Peng, Shubin Dong, Xiaofei Xia, and Liangcheng ZhaoFrom:PeerJ (Vol. 7) Peer-Reviewed

  May 3, 20197,673 words Article 1480LBackground Elaiosomes are specialized fleshy and edible seed appendages dispersed by ants. Lipids are the primary components of elaiosomes. Chelidonium majus is a well-known plant, the seeds of which are dispersed by...

• Diet and Alzheimer'a[euro][TM]s disease risk factors or prevention: the current evidence

  Authors:Vincenzo Solfrizzi, Francesco Panza, Vincenza Frisardi, Davide Seripa, Giancarlo Logroscino, Bruno P Imbimbo, et al.From:Expert Review of Neurotherapeutics (Vol. 11, Issue 5) Peer-Reviewed

  May 201126,039 words Article 1640LAuthor(s): Vincenzo Solfrizzi 1 , Francesco Panza [[dagger]] 5 , Vincenza Frisardi 1 , Davide Seripa 2 , Giancarlo Logroscino 3 , Bruno P Imbimbo 4 , Alberto Pilotto 2 Keywords : alcohol consumption;...

• Metabolic Engineering Camelina sativa with Fish Oil-Like Levels of DHA

  Authors:James R. Petrie, Pushkar Shrestha, Srinivas Belide, Yoko Kennedy, Geraldine Lester, Qing Liu, et al.From:PLoS ONE (Vol. 9, Issue 1) Peer-Reviewed

  Jan. 21, 20144,203 words Article 1520LAuthor(s): James R. Petrie 1, Pushkar Shrestha 1, Srinivas Belide 1, Yoko Kennedy 1, Geraldine Lester 1, Qing Liu 1, Uday K. Divi 1, Roger J. Mulder 3, Maged P. Mansour 2, Peter D. Nichols 2, Surinder P. Singh 1,*...