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• Select Modeling SAGE tag formation and its effects on data interpretation within a Bayesian framework

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  Modeling SAGE tag formation and its effects on data interpretation within a Bayesian framework

  Authors:Michael A. Gilchrist, Hong Qin, and Russell ZaretzkiFrom:BMC Bioinformatics (Vol. 8) Peer-Reviewed

  Oct. 18, 20078,981 words Article 1530LBackground Serial Analysis of Gene Expression (SAGE) is a high-throughput method for inferring mRNA expression levels from the experimentally generated sequence based tags. Standard analyses of SAGE data, however,...
• Select Nonlinear model-based method for clustering periodically expressed genes

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  Nonlinear model-based method for clustering periodically expressed genes

  Authors:Li-Ping Tian, Li-Zhi Liu, Qian-Wei Zhang, and Fang-Xiang WuFrom:The Scientific World Journal (Vol. 11) Peer-Reviewed

  Annual 20113,790 words Report 1550LClustering periodically expressed genes from their time-course expression data could help understand the molecular mechanism of those biological processes. In this paper, we propose a nonlinear model-based clustering...
• Select A systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE)

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  A systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE)

  Authors:Juan Hou, Anita M. Charters, Sam C. Lee, Yongjun Zhao, Mona K. Wu, Steven JM. Jones, et al.From:BMC Developmental Biology (Vol. 7) Peer-Reviewed

  Aug. 2, 20078,034 words Report 1430LBackground The embryonic definitive endoderm (DE) gives rise to organs of the gastrointestinal and respiratory tract including the liver, pancreas and epithelia of the lung and colon. Understanding how DE progenitor...
• Select Wiser gene annotations with 5' SAGE?

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  Wiser gene annotations with 5' SAGE?

  Author:Cathy HoldingFrom:The Scientist (Vol. 18, Issue 20) Peer-Reviewed

  Oct. 25, 2004528 words Article Serial analysis of gene expression (SAGE) has been used extensively to map and quantify transcripts in different tissues. But the technique, which extracts short oligos (14-21 bp long) from the 3' ends of pooled mRNAs,...
• Select High-throughput identification of mutations using a combination of CEL I fragmentation and SAGE technology

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  High-throughput identification of mutations using a combination of CEL I fragmentation and SAGE technology

  Authors:Chi Zhang, Yuan-Yuan Li, Xian-Liang Wang, Li-Jun Zhang, Xiao-Bo Li, You-Jie Wang, et al.From:Genetic Testing and Molecular Biomarkers (Vol. 13, Issue 1) Peer-Reviewed

  February-March 20093,980 words Report A new method to detect mutations based on the serial analysis of gene expression (SAGE) technique, ligation-mediated (LM) PCR, and recombinant nuclease CEL I named LM-SAGE assay is reported in the present study....
• Select Deep analysis of cellular transcriptomes - LongSAGE versus classic MPSS

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  Deep analysis of cellular transcriptomes - LongSAGE versus classic MPSS

  Authors:Lawrence Hene, Vattipally B. Sreenu, Mai T. Vuong, S Hussain I. Abidi, Julian K. Sutton, Sarah L. Rowland-Jones, et al.From:BMC Genomics (Vol. 8) Peer-Reviewed

  Sept. 24, 200711,484 words Article 1550LBackground Deep transcriptome analysis will underpin a large fraction of post-genomic biology. 'Closed' technologies, such as microarray analysis, only detect the set of transcripts chosen for analysis, whereas...
• Select Differential gene expression in an elite hybrid rice cultivar ( Oryza sativa, L ) and its parental lines based on SAGE data

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  Differential gene expression in an elite hybrid rice cultivar ( Oryza sativa, L ) and its parental lines based on SAGE data

  Authors:Shuhui Song, Hongzhu Qu, Chen Chen, Songnian Hu, and Jun YuFrom:BMC Plant Biology (Vol. 7) Peer-Reviewed

  Sept. 19, 20078,471 words Brief article 1540LBackground It was proposed that differentially-expressed genes, aside from genetic variations affecting protein processing and functioning, between hybrid and its parents provide essential candidates for studying...
• Select Serial analysis of gene expression reveals differential expression between endometriosis and normal endometrium. Possible roles for AXL and SHC1 in the pathogenesis of endometriosis

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  Serial analysis of gene expression reveals differential expression between endometriosis and normal endometrium. Possible roles for AXL and SHC1 in the pathogenesis of endometriosis

  Authors:Hiroshi Honda, Fermin F. Barrueto, Jean Gogusev, Dwight D. Im, and Patrice J. MorinFrom:Reproductive Biology and Endocrinology (Vol. 6) Peer-Reviewed

  Dec. 2, 20086,885 words Clinical report Background Endometriosis is a clinical condition that affects up to 10% of the women of reproductive age. Endometriosis is characterized by the presence of endometrial tissues outside the uterine cavity and can lead...
• Select New gene-expression profiles to predict outcome in hepatocellular carcinoma

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  New gene-expression profiles to predict outcome in hepatocellular carcinoma

  From:Nature Clinical Practice Gastroenterology and Hepatology (Vol. 6, Issue 1) Peer-Reviewed

  Jan. 2009263 words Brief article, Clini... 1510LCurrent histopathological and anatomical methods of predicting outcome in early hepatocellular carcinoma (HCC) are not particularly effective in early disease. Hoshida et al. undertook genome-wide expression profiling...
• Select Plant Gene Expression Center

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  Plant Gene Expression Center

  Author:Philip H. AbelsonFrom:Science (Vol. 253, Issue 5027) Peer-Reviewed

  Sept. 27, 1991722 words Editorial An important experiment in the support of plan research is being conducted in Albany, California, not far from the University at Berkeley. The Plant Gene Expression Center (PGEC) effectively began operations in 1987 as...
• Select Study challenges long-held assumption of gene expression in embryonic stem cells

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  Study challenges long-held assumption of gene expression in embryonic stem cells

  From:Stem Cell Week

  July 15, 2013460 words Article 1590LBy a News Reporter-Staff News Editor at Stem Cell Week -- Whitehead Institute researchers have determined that the transcription factor Nanog, which plays a critical role in the self-renewal of embryonic stem cells, is...
• Select Micro-RNAs in IVF outcome

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  Micro-RNAs in IVF outcome

  Authors:Saeid Ghorbian and Ahmad ZonouziFrom:Indian Journal of Human Genetics (Vol. 19, Issue 2) Peer-Reviewed

  April-June 2013379 words Brief article, Repor... 1560LByline: Saeid. Ghorbian, Ahmad. Zonouzi Sir, The advancement on assisted reproductive technologies increased hope to childbearing in couples of infertile. In vitro fertilization (IVF) is one of these technologies....
• Select Update on microbe-induced epigenetic changes: bacterial effectors and viral oncoproteins as epigenetic dysregulators

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  Update on microbe-induced epigenetic changes: bacterial effectors and viral oncoproteins as epigenetic dysregulators

  Authors:Hans Helmut Niller, Ferenc Banati, Katalin Nagy, Krisztina Buzas, and Janos MinarovitsFrom:Future Virology (Vol. 8, Issue 11)

  Nov. 201311,394 words Article 1630LAuthor(s): Hans Helmut Niller 1 , Ferenc Banati 2 , Katalin Nagy 3 , Krisztina Buzas 4 , Janos Minarovits [*] 5 Keywords * DNA methylation; epigenetic regulation; histone modification; oncovirus;...
• Select An insight into pleiotropic regulators Agr and Sar: molecular probes paving the new way for antivirulent therapy

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  An insight into pleiotropic regulators Agr and Sar: molecular probes paving the new way for antivirulent therapy

  Authors:Rekha Arya and S Adline PrincyFrom:Future Microbiology (Vol. 8, Issue 10)

  Oct. 20138,337 words Report 1500LAuthor(s): Rekha Arya 1 , S Adline Princy [*] 2 Keywords * agr locus; biofilm; community-acquired MRSA; pathogenesis; sar locus; Staphylococcus aureus Quorum-sensing system: evolution of staphylococcal...
• Select A gene expression signature for RSV: clinical implications and limitations

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  A gene expression signature for RSV: clinical implications and limitations

  Author:Peter J.M. OpenshawFrom:PLoS Medicine (Vol. 10, Issue 11) Peer-Reviewed

  Nov. 20131,832 words Report 1510LEspecially during the first year of life, children are plagued by pathogens jockeying for position at the mucosal surfaces [1]. Respiratory viruses have diverse pathways to success: influenza is highly infectious and...
• Select Gene expression profiling and histomorphometric analyses of the early bone healing response around nanotextured implants

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  Gene expression profiling and histomorphometric analyses of the early bone healing response around nanotextured implants

  Authors:Rima M Wazen, Shingo Kuroda, Clarice Nishio, Karine Sellin, John B Brunski, and Antonio NanciFrom:Nanomedicine (Vol. 8, Issue 9) Peer-Reviewed

  Sept. 20135,059 words Report 1530LAuthor(s): Rima M Wazen 1 , Shingo Kuroda 1 2 , Clarice Nishio 1 , Karine Sellin 1 , John B Brunski 3 , Antonio Nanci [*] 4 Keywords : bone; DNA microarray; histomorphometry; nanotopography; titanium alloy...
• Select A better way to turn off neurons

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  A better way to turn off neurons

  Author:Daniel EvankoFrom:Nature Methods (Vol. 11, Issue 6) Peer-Reviewed

  June 2014369 words Brief article, Repor... 1450LEngineering of channelrhodopsin into a [Cl.sup.-] channel creates a powerful tool for light-mediated inhibition of neurons. Use of light to control cellular activity has emerged as a powerful neuroscience research...
• Select Early life trauma leaves mark on future generations

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  Early life trauma leaves mark on future generations

  From:Lab Animal (Vol. 43, Issue 6) Peer-Reviewed

  June 2014209 words Brief article, Repor... 1240LStress leaves epigenetic marks on DNA that change the way genes are expressed without altering their sequences. Isabella Manuy (University of Zurich, Switzerland) and her colleagues investigated the epigenetic effects...
• Select J Matern Fetal Neonatal Med.: Glycosylation pattern and axin expression in normal and IUGR placentae

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  J Matern Fetal Neonatal Med.: Glycosylation pattern and axin expression in normal and IUGR placentae

  Authors:A. Vukasovic, D. Grbesa, Martic T. Nikuseva, V. Kusec, B. Miskovic, A. Serman, et al.From:Croatian Medical Journal (Vol. 55, Issue 3) Peer-Reviewed

  June 2014211 words Brief article 1460LObjective: The aim of this study was to investigate the protein glycosylation pattern and AXIN1 protein expression n human placentae of normal pregnancies and compare them with placentae of pregnancies complicated with...
• Select Levels of circulating microRNAs predict severity of spinal cord contusion in mice

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  Levels of circulating microRNAs predict severity of spinal cord contusion in mice

  From:Nature Reviews Neurology (Vol. 10, Issue 7) Peer-Reviewed

  July 2014103 words Brief article 1170LAssessing spinal cord injury is difficult because some acute clinical impairments resolve with time. A team from Hiroshima University, Japan, have found three microRNAs that correlate with damage severity just 12-24 h...