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• Select New Tissue and Cell Research Research from National Institute of Genetic Engineering and Biotechnology Discussed

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  New Tissue and Cell Research Research from National Institute of Genetic Engineering and Biotechnology Discussed

  From:Stem Cell Week

  Feb. 11, 2013383 words Brief article, Repor... 1370LBy a News Reporter-Staff News Editor at Stem Cell Week -- Data detailed on Tissue and Cell Research have been presented. According to news reporting originating from Tehran, Iran, by NewsRx correspondents, research...
• Select Diabetes genetic predisposition score and cardiovascular complications among patients with type 2 diabetes

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  Diabetes genetic predisposition score and cardiovascular complications among patients with type 2 diabetes

  Authors:Qibin Qi, James B. Meigs, Kathryn M. Rexrode, Frank B. Hu, and Lu QiFrom:Diabetes Care (Vol. 36, Issue 3) Peer-Reviewed

  Mar. 20131,834 words Article 1330LOBJECTIVE--To examine the association between genetic predisposition to type 2 diabetes (T2D) and risk of cardiovascular disease (CVD) among patients with T2D. RESEARCH DESIGN AND METHODS--The current study included...
• Select Study challenges long-held assumption of gene expression in embryonic stem cells

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  Study challenges long-held assumption of gene expression in embryonic stem cells

  From:Stem Cell Week

  July 15, 2013460 words Article 1590LBy a News Reporter-Staff News Editor at Stem Cell Week -- Whitehead Institute researchers have determined that the transcription factor Nanog, which plays a critical role in the self-renewal of embryonic stem cells, is...
• Select Associations between genetic variants in the TGF-[beta] signaling pathway and breast cancer risk among Hispanic and non-Hispanic white women

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  Associations between genetic variants in the TGF-[beta] signaling pathway and breast cancer risk among Hispanic and non-Hispanic white women

  Authors:Stephanie D. Boone, Kathy B. Baumgartner, Richard N. Baumgartner, Avonne E. Connor, Christina M. Pinkston, Esther M. John, et al.From:Breast Cancer Research and Treatment (Vol. 141, Issue 2) Peer-Reviewed

  Sept. 20135,911 words Article 1450LThe TGF-[beta] signaling pathway has a significant role in breast cancer initiation and promotion by regulating various cellular processes. We evaluated whether genetic variation in eight genes (TGF-[beta]1,...
• Select Promoting a new brain tumor mutation: TERT promoter mutations in CNS tumors

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  Promoting a new brain tumor mutation: TERT promoter mutations in CNS tumors

  Authors:Zachary J. Reitman, Christopher J. Pirozzi, and Hai YanFrom:Acta Neuropathologica (Vol. 126, Issue 6) Peer-Reviewed

  Dec. 20132,689 words Article 1520LGenomic research has recently linked two fundamental observations about the molecular biology of cancer. The first of these pivotal observations is that cancer is essentially a genetic disease, with tumor cells driven...
• Select Haplotype data for 23 y-chromosome markers in a reference sample from Bosnia and Herzegovina

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  Haplotype data for 23 y-chromosome markers in a reference sample from Bosnia and Herzegovina

  Authors:Lejla Kovacevic, Vera Fatur-Ceric, Negra Hadzic, Jasmina Cakar, Dragan Primorac, and Damir MarjanovicFrom:Croatian Medical Journal (Vol. 54, Issue 3) Peer-Reviewed

  June 20131,676 words Report 1410LAim To detect polymorphisms of 23 Y-chromosomal short tandem repeat (STR) loci, including 6 new loci, in a reference database of male population of Bosnia and Herzegovina, as well as to assess the importance of...
• Select Integrating GWASs and protein interactions

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  Integrating GWASs and protein interactions

  From:Nature Reviews Genetics (Vol. 15, Issue 1) Peer-Reviewed

  Jan. 2014117 words Brief article 1290LHan et al. integrated data from genome-wide association studies (GWASs) with data from a human protein interaction network and identified a network of 39 genes that are associated with alcohol dependence. These genes...
• Select The effect of diet on the intestinal epigenome

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  The effect of diet on the intestinal epigenome

  Authors:Ian T Johnson and Nigel J BelshawFrom:Epigenomics (Vol. 6, Issue 2) Peer-Reviewed

  Apr. 201410,561 words Report 2100LAuthor(s): Ian T Johnson [*] aff1 , Nigel J Belshaw aff1 Keywords: colon; DNA methylation; DNA methyltransferase; folic acid; mucosa; rectum Background The concept of the mammalian epigenome, indeed the very...
• Select Myocardial calcium signaling in physiology and disease

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  Myocardial calcium signaling in physiology and disease

  Authors:Soojeong Kang and Djamel LebecheFrom:Journal of Receptor, Ligand and Channel Research (Vol. 6) Peer-Reviewed

  Annual 201310,549 words Report 2320LIt is now well-established that calcium ([Ca.sup.2+]) is a critical regulator of myocardial function and that abnormalities in cardiomyocyte intracellular [Ca.sup.2+] dynamics contribute to pathophysiologic changes...
• Select Findings from Wellcome Trust Sanger Institute Has Provided New Information about Stem Cells (Genetic background drives transcriptional variation in human induced pluripotent stem cells)

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  Findings from Wellcome Trust Sanger Institute Has Provided New Information about Stem Cells (Genetic background drives transcriptional variation in human induced pluripotent stem cells)

  From:Stem Cell Week

  Aug. 18, 2014374 words Brief article, Repor... 1430LBy a News Reporter-Staff News Editor at Stem Cell Week -- New research on Stem Cell Research is the subject of a report. According to news reporting originating from Cambridge, United Kingdom, by NewsRx correspondents,...
• Select Mutations ID'ed for phenytoin-related skin reactions

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  Mutations ID'ed for phenytoin-related skin reactions

  Authors:Mary and MoonFrom:Skin & Allergy News (Vol. 45, Issue 9)

  Sept. 2014395 words Article 1680LMutations in the CYP2C genes on chromosome 10 appear to predispose carriers to severe adverse cutaneous reactions to the antiepileptic drug phenytoin. Researchers performed a genome-wide association study of more...
• Select Reports from Indian Institute of Science Education and Research Highlight Recent Findings in Stem Cells (A high-resolution gene expression map of the Arabidopsis shoot meristem stem cell niche)

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  Reports from Indian Institute of Science Education and Research Highlight Recent Findings in Stem Cells (A high-resolution gene expression map of the Arabidopsis shoot meristem stem cell niche)

  From:Stem Cell Week

  Sept. 29, 2014417 words Report 1270LBy a News Reporter-Staff News Editor at Stem Cell Week -- Investigators publish new report on Stem Cell Research. According to news reporting out of Mohali, India, by NewsRx editors, research stated, "The shoot apical...
• Select Adenosine monophosphate-activated protein kinase activation enhances embryonic neural stem cell apoptosis in a mouse model of amyotrophic lateral sclerosis

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  Adenosine monophosphate-activated protein kinase activation enhances embryonic neural stem cell apoptosis in a mouse model of amyotrophic lateral sclerosis

  Authors:Yanling Sui, Zichun Zhao, Rong Liu, Bin Cai, and Dongsheng FanFrom:Neural Regeneration Research (Vol. 9, Issue 19) Peer-Reviewed

  Oct. 1, 20145,326 words Report 1400LByline: Yanling. Sui, Zichun. Zhao, Rong. Liu, Bin. Cai, Dongsheng. Fan Alterations in embryonic neural stem cells play crucial roles in the pathogenesis of amyotrophic lateral sclerosis. We hypothesized that...
• Select Data on Transcription Factors Reported by Researchers at University of Texas (Negative Regulation of DsbA-L Gene Expression by the Transcription Factor Sp1)

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  Data on Transcription Factors Reported by Researchers at University of Texas (Negative Regulation of DsbA-L Gene Expression by the Transcription Factor Sp1)

  From:Obesity, Fitness & Wellness Week

  Dec. 27, 2014391 words Report 1420LBy a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on Proteins. According to news reporting originating in San Antonio, Texas, by NewsRx journalists, research...
• Select Microsatellite analysis in the genome of Acanthaceae: An in silico approach

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  Microsatellite analysis in the genome of Acanthaceae: An in silico approach

  Authors:Priyadharsini Kaliswamy, Srividhya Vellingiri, Bharathi Nathan, and Saravanakumar SelvarajFrom:Pharmacognosy Magazine (Vol. 11, Issue 41) Peer-Reviewed

  January-March 20152,218 words Report 1720LByline: Priyadharsini. Kaliswamy, Srividhya. Vellingiri, Bharathi. Nathan, Saravanakumar. Selvaraj Background: Acanthaceae is one of the advanced and specialized families with conventionally used medicinal plants....
• Select DNA clock proves tough to set: geneticists meet to work out why the rate of mutation in the human genome is hard to pin down

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  DNA clock proves tough to set: geneticists meet to work out why the rate of mutation in the human genome is hard to pin down

  Author:Ewen CallawayFrom:Nature (Vol. 519, Issue 7542) Peer-Reviewed

  Mar. 12, 20151,067 words Article 1500LMathematicians keep refining n even though they know it to more than 12 trillion digits; physicists beat themselves up because they cannot pin down the gravitational constant beyond three significant figures....
• Select The genome and transcriptome of a single cell

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  The genome and transcriptome of a single cell

  From:Nature Methods (Vol. 12, Issue 3) Peer-Reviewed

  Mar. 2015147 words Brief article 1430LSingle-cell sequencing enables the study of tissue heterogeneity and rare cells, but it has been impossible to directly connect genotype with gene expression from such data. Dey et al. now describe genomic DNA-mRNA...
• Select Effect of selected endocrine disruptors on male urogenital system development and reproductive parameters in rats/Effek van selektiewe endokrien-steurende chemiese stowwe op manlike urogenitale sisteem ontwikkeling en voortplantingsparameters in rotte

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  Effect of selected endocrine disruptors on male urogenital system development and reproductive parameters in rats/Effek van selektiewe endokrien-steurende chemiese stowwe op manlike urogenitale sisteem ontwikkeling en voortplantingsparameters in rotte

  Authors:S. Patrick, M.S. Bornman, A.M. Joubert, and C. de JagerFrom:Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie (Vol. 33, Issue 1) Peer-Reviewed

  Jan. 2014717 words Report 1510LEndocrine disrupting chemical exposure may lead to impairment of hormonal processes affecting reproductive development and function. The study investigated effects of EDC exposure on urogenital system development,...
• Select Functions of noncoding sequences in mammalian genomes

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  Functions of noncoding sequences in mammalian genomes

  Authors:L.I. Patrushev and T.F. KovalenkoFrom:Biochemistry (Moscow) (Vol. 79, Issue 13) Peer-Reviewed

  Dec. 15, 201423,762 words Report 1430LMost of the mammalian genome consists of nucleotide sequences not coding for proteins. Exons of genes make up only 3% of the human genome, while the significance of most other sequences remains unknown. Recent genome...
• Select Distinct expression of cytokeratin, N-cadherin and CD133 in circulating tumor cells of metastatic breast cancer patients

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  Distinct expression of cytokeratin, N-cadherin and CD133 in circulating tumor cells of metastatic breast cancer patients

  Authors:Carolin Bock, Brigitte Rack, Jens Huober, Ulrich Andergassen, Udo Jeschke, and Sophie Doisneau-SixouFrom:Future Oncology (Vol. 10, Issue 10) Peer-Reviewed

  Aug. 20149,453 words Report 1620LAuthor(s): Carolin Bock aff1 , Brigitte Rack aff1 , Jens Huober aff2 , Ulrich Andergassen aff1 , Udo Jeschke aff1 , Sophie Doisneau-Sixou [*] aff3 KEYWORDS breast cancer; CD133; circulating tumor cells; EMT;...