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• Select Dengue control

  1

  Dengue control

  From:Nature (Vol. 505, Issue 7486) Peer-Reviewed

  Feb. 6, 201479 words Brief article 1520LPanama has joined a handful of nations trying to combat dengue fever using genetically modified mosquitoes developed by Oxitec, a biotechnology firm in Oxford, UK (see go.nature. com/tht55x). The company announced on 28...
• Select Transgenesis mediada por espermatozoides en la especie porcina: efecto de la presencia de ADN exogeno sobre la calidad seminal y evaluacion de la produccion in vivo de embriones transgenicos

  2

  Transgenesis mediada por espermatozoides en la especie porcina: efecto de la presencia de ADN exogeno sobre la calidad seminal y evaluacion de la produccion in vivo de embriones transgenicos

  Authors:Francisco Alberto Garcia-Vazquez, Salvador Ruiz, Luis Alberto Grullon, Aitor de Ondiz, Alfonso Gutierrez-Adan, and Joaquin GadeaFrom:Revista Científica de la Facultad de Ciencias Veterinarias (Vol. 20, Issue 1) Peer-Reviewed

  January-February 20105,082 words Report Una alternativa biotecnológica para la producción de animales transgénicos es la transgénesis mediada por espermatozoides (SMGT), basada en la habilidad de las células espermáticas de unir e interiorizar ADN exógeno. En...
• Select GM mice reveal the secret to a painless life

  3

  GM mice reveal the secret to a painless life

  From:Obesity, Fitness & Wellness Week

  Dec. 26, 2015622 words Article 1430L2015 DEC 26 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- People born with a rare genetic mutation are unable to feel pain, but previous attempts to recreate this effect with...
• Select Mouse Transgenesis in a Single Locus with Independent Regulation for Multiple Fluorophores

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  Mouse Transgenesis in a Single Locus with Independent Regulation for Multiple Fluorophores

  Authors:Joseph D. Dougherty, Juliet Zhang, Huifen Feng, Shiaoching Gong, and Nathaniel HeintzFrom:PLoS ONE (Vol. 7, Issue 7) Peer-Reviewed

  July 12, 20126,968 words Article 1480LAuthor(s): Joseph D. Dougherty 1 , 2 , * , Juliet Zhang 1 , Huifen Feng 3 , Shiaoching Gong 3 , Nathaniel Heintz 1 , 3 , 4 Introduction Over the last three decades, transgenic mice have become a mainstay of...
• Select Serum metabolomic profile in genetically modified cows carrying human [alpha]-lactalbumin gene

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  Serum metabolomic profile in genetically modified cows carrying human [alpha]-lactalbumin gene

  Authors:Qin Wang, Wei Fu, Xiaofei Liu, Jianwu Wang, Chunyan Feng, Songyin Qiu, et al.From:Molecular Medicine Reports (Vol. 16, Issue 6) Peer-Reviewed

  Dec. 20174,284 words Report 1390LThe present study aimed to investigate the serum metabolomic profiles in genetically modified cows carrying and expressing human lactalbumin [alpha] (LALBA) and non-LALBA cows, and identify altered metabolic...
• Select Data on Obesity Described by a Researcher at University of Bari Aldo Moro (The New Frontier in Oxytocin Physiology: The Oxytonic Contraction).

  6

  Data on Obesity Described by a Researcher at University of Bari Aldo Moro (The New Frontier in Oxytocin Physiology: The Oxytonic Contraction).

  From:Obesity, Fitness & Wellness Week

  Aug. 8, 2020437 words Article 1320L2020 AUG 8 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- A new study on obesity is now available. According to news originating from Bari, Italy, by NewsRx correspondents,...
• Select Findings from National Agriculture and Food Research Organization Provide New Insights into Antirheumatics [Structural insight and stability of TNFR-Fc fusion protein (Etanercept) produced by Using transgenic silkworms].

  7

  Findings from National Agriculture and Food Research Organization Provide New Insights into Antirheumatics [Structural insight and stability of TNFR-Fc fusion protein (Etanercept) produced by Using transgenic silkworms].

  From:Obesity, Fitness & Wellness Week

  Aug. 22, 2020394 words Brief article 1290L2020 AUG 22 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Researchers detail new data in Drugs and Therapies - Antirheumatics. According to news originating from Ibaraki, Japan,...
• Select PINK1/PARKIN signalling in neurodegeneration and neuroinflammation.

  8

  PINK1/PARKIN signalling in neurodegeneration and neuroinflammation.

  Authors:Peter M. J. Quinn, Paula I. Moreira, António Francisco Ambrósio, and C. Henrique AlvesFrom:Acta Neuropathologica Communications (Vol. 8, Issue 1) Peer-Reviewed

  Nov. 9, 202012,428 words Article 1510LMutations in the PTEN-induced kinase 1 (PINK1) and Parkin RBR E3 ubiquitin-protein ligase (PARKIN) genes are associated with familial forms of Parkinson's disease (PD). PINK1, a protein kinase, and PARKIN, an E3...
• Select Transgene Expression Is Associated with Copy Number and Cytomegalovirus Promoter Methylation in Transgenic Pigs

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  Transgene Expression Is Associated with Copy Number and Cytomegalovirus Promoter Methylation in Transgenic Pigs

  Authors:Qingran Kong, Meiling Wu, Yanjun Huan, Li Zhang, Haiyan Liu, Gerelchimeg Bou, et al.From:PLoS ONE (Vol. 4, Issue 8) Peer-Reviewed

  Aug. 18, 20096,975 words Article 1350LTransgenic animals have been used for years to study gene function, produce important proteins, and generate models for the study of human diseases. However, inheritance and expression instability of the transgene in...
• Select Regulation of a Vascular Plexus by gata4 Is Mediated in Zebrafish through the Chemokine sdf1a

  10

  Regulation of a Vascular Plexus by gata4 Is Mediated in Zebrafish through the Chemokine sdf1a

  Authors:Ingrid Torregroza, Audrey Holtzinger, Karen Mendelson, Ting-Chun Liu, Timothy Hla, and Todd EvansFrom:PLoS ONE (Vol. 7, Issue 10) Peer-Reviewed

  Oct. 3, 20129,882 words Article 1480LUsing the zebrafish model we describe a previously unrecognized requirement for the transcription factor gata4 controlling embryonic angiogenesis. The development of a vascular plexus in the embryonic tail, the caudal...
• Select Evaluation of TorsinA as a Target for Parkinson Disease Therapy in Mouse Models

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  Evaluation of TorsinA as a Target for Parkinson Disease Therapy in Mouse Models

  Authors:Xinru Li, Jenny Lee, Dee Parsons, Karen Janaurajs, and David G. StandaertFrom:PLoS ONE (Vol. 7, Issue 11) Peer-Reviewed

  Nov. 21, 20126,993 words Report 1410LParkinson disease (PD) is a common and disabling disorder. No current therapy can slow or reverse disease progression. An important aspect of research in this field is target validation, a systematic approach to...
• Select Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain

  12

  Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain

  Authors:Guohao Wang, Huaqiang Yang, Sen Yan, Chuan-En Wang, Xudong Liu, Bentian Zhao, et al.From:Molecular Neurodegeneration (Vol. 10, Issue 1) Peer-Reviewed

  Sept. 3, 201510,760 words Article 1560LBackground TAR DNA-binding protein 43 (TDP-43) is a nuclear protein, but it is redistributed in the neuronal cytoplasm in both amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Because...
• Select Accumulation of genetic variants associated with immunity in the selective breeding of broilers

  13

  Accumulation of genetic variants associated with immunity in the selective breeding of broilers

  Authors:Angela Zou, Kerry Nadeau, Pauline W. Wang, Jee Yeon Lee, David S. Guttman, Shayan Sharif, et al.From:BMC Genetics (Vol. 21, Issue 1) Peer-Reviewed

  Jan. 17, 20207,958 words Report 1580LBackground To satisfy an increasing demand for dietary protein, the poultry industry has employed genetic selection to increase the growth rate of broilers by over 400% in the past 50 years. Although modern broilers...
• Select Impact of Temporal Variation on Design and Analysis of Mouse Knockout Phenotyping Studies

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  Impact of Temporal Variation on Design and Analysis of Mouse Knockout Phenotyping Studies

  Authors:Natasha A. Karp, Anneliese O. Speak, Jacqueline K. White, David J. Adams, Martin Hrabe de Angelis, Yann Herault, et al.From:PLoS ONE (Vol. 9, Issue 10) Peer-Reviewed

  Oct. 24, 20145,197 words Article 1400LA significant challenge facing high-throughput phenotyping of in-vivo knockout mice is ensuring phenotype calls are robust and reliable. Central to this problem is selecting an appropriate statistical analysis that...
• Select Goat milk with and without increased concentrations of lysozyme improves repair of intestinal cell damage induced by enteroaggregative Escherichia coli

  15

  Goat milk with and without increased concentrations of lysozyme improves repair of intestinal cell damage induced by enteroaggregative Escherichia coli

  Authors:Eunice B Carvalho, Elizabeth A Maga, Josiane S Quetz, Ila FN Lima, Hemerson YF MagalhA[pounds sterling]es, Felipe AR Rodrigues, et al.From:BMC Gastroenterology (Vol. 12, Issue 1) Peer-Reviewed

  Aug. 11, 20125,582 words Report 1520LBackground Enteroaggregative Escherichia coli (EAEC) causes diarrhea, malnutrition and poor growth in children. Human breast milk decreases disease-causing bacteria by supplying nutrients and antimicrobial factors...
• Select Precision gene editing paves way for transgenic monkeys: despite political challenges, engineered primates could be better disease models than mice

  16

  Precision gene editing paves way for transgenic monkeys: despite political challenges, engineered primates could be better disease models than mice

  Author:Helen ShenFrom:Nature (Vol. 503, Issue 7474) Peer-Reviewed

  Nov. 7, 20131,028 words Article 1410LAnthony Chan spent two years creating the first five monkeys in the world to be genetically engineered with human mutations--in this case, for Huntington's disease. But three of the five monkeys, reported in 2008,...
• Select Delayed phenotypic expression of growth hormone transgenesis during early ontogeny in Atlantic salmon (Salmo salar)?

  17

  Delayed phenotypic expression of growth hormone transgenesis during early ontogeny in Atlantic salmon (Salmo salar)?

  Authors:Darek T.R. Moreau, A. Kurt Gamperl, Garth L. Fletcher, and Ian A. FlemingFrom:PLoS ONE (Vol. 9, Issue 4) Peer-Reviewed

  Apr. 20147,080 words Report 1500LShould growth hormone (GH) transgenic Atlantic salmon escape, there may be the potential for ecological and genetic impacts on wild populations. This study compared the developmental rate and respiratory metabolism of...
• Select Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds.

  18

  Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds.

  Authors:Marta Perez-Rando, Simon Dujardin, Rachel E. Bennett, Caitlin Commins, Tara Nibhanupudy, and Bradley T. HymanFrom:Acta Neuropathologica Communications (Vol. 8, Issue 1) Peer-Reviewed

  Oct. 19, 20205,164 words Article 1670LRecent studies suggest that misfolded tau molecules can be released, and taken up by adjacent neurons, propagating proteopathic seeds across neural systems. Yet critical to understanding whether tau propagation is...
• Select Studies from University of California Yield New Information about Lentivirus

  19

  Studies from University of California Yield New Information about Lentivirus

  From:Obesity, Fitness & Wellness Week

  Mar. 19, 2011268 words Brief article 1340LData detailed in 'Lentiviral transgenesis' have been presented. According to a study from the United States, "Conventional DNA injection-based methods are successful in generating transgenic animals and have remained...
• Select A chicken bioreactor for efficient production of functional cytokines

  20

  A chicken bioreactor for efficient production of functional cytokines

  Authors:Lissa R. Herron, Clare Pridans, Matthew L. Turnbull, Nikki Smith, Simon Lillico, Adrian Sherman, et al.From:BMC Biotechnology (Vol. 18, Issue 1) Peer-Reviewed

  Dec. 29, 20187,319 words Report 1580LBackground The global market for protein drugs has the highest compound annual growth rate of any pharmaceutical class but their availability, especially outside of the US market, is compromised by the high cost of...