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    Academic Journals

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• CD34+ cells from dental pulp stem cells with a ZFN-mediated and homology-driven repair-mediated locus-specific knock-in of an artificial [beta]-globin gene

  Authors:S Chattong, O Ruangwattanasuk, W Yindeedej, A Setpakdee, and K ManothamFrom:Gene Therapy (Vol. 24, Issue 7) Peer-Reviewed

  July 20176,151 words Report 1520LIn humans, mutations in the [beta]-globin gene (HBB) have two important clinical manifestations: [beta]-thalassemia and sickle cell disease. The progress in genome editing and stem cell research may be relevant to the...

• Erythropoiesis stimulants: use with caution in cancer patients

  From:Reactions Weekly (Issue 1339)

  Feb. 19, 2011142 words Brief article, Repor... 1300LUpdated guidelines on the use of erythropoiesis-stimulating agents (ESAs) for the treatment of chemotherapy-induced anaemia suggest caution be taken when deciding how to treat cancer patients. The guidelines, first...

• Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD[8.sup.+] T cells

  Authors:Claudia Wrzesinski, Chrystal M. Paulos, Luca Gattinoni, Douglas C. Palmer, Andrew Kaiser, Zhiya Yu, et al.From:Journal of Clinical Investigation (Vol. 117, Issue 2) Peer-Reviewed

  Feb. 20077,484 words Article 1560LDepleting host immune elements with nonmyeloablative regimens prior to the adoptive transfer of tumor-specific CD[8.sup.+] T cells significantly enhances tumor treatment. In the current study, superior antitumor...

• Hematopoietic-Prostaglandin D2 synthase through PGD2 production is involved in the adult ovarian physiology

  Authors:Andalib Farhat, Pascal Philibert, Charles Sultan, Francis Poulat, and Brigitte Boizet-BonhoureFrom:Journal of Ovarian Research (Vol. 4) Peer-Reviewed

  Feb. 25, 20117,418 words Report 1530LBackground The prostaglandin D2 (PGD2) pathway is involved in numerous biological processes and while it has been identified as a partner of the embryonic sex determining male cascade, the roles it plays in ovarian...

• Erythropoiesis-stimulating agents versus RBC transfusion in MDS: comparison of long-term outcomes

  Author:Suneel D MundleFrom:Future Oncology (Vol. 3, Issue 4) Peer-Reviewed

  Aug. 20074,650 words Clinical report Author(s): Suneel D Mundle 1 Keywords: erythropoietin; erythropoiesis-stimulating agent; hematopoietic growth factor; leukemic transformation; myelodysplastic syndrome; red blood cell transfusion; survival The...

• Advantages of Every-3-Week Dosing of Erythropoietic Agents to Manage Chemotherapy-Induced Anemia

  From:OncologyPeer-Reviewed

  June 1, 20064,219 words Article 1900LJoan Clark, RN, MSN, BC, ANP Alvin Schergen, MD, FACP St. Louis Hematology Oncology Specialists, Inc St. Louis, Missouri Patients receiving chemotherapy for cancer often develop anemia, which can contribute...

• Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development

  Authors:James L. Clements, Baoli Yang, Susan E. Ross-Barta, Steve L. Eliason, Ronald F. Hrstka, Roger A. Williamson, et al.From:Science (Vol. 281, Issue 5375) Peer-Reviewed

  July 17, 19982,805 words Article The leukocyte-specific adapter molecule SLP-76 (Src homology 2 domain-containing leukocyte protein of 76 kilodaltons) is rapidly phosphorylated on tyrosine residues after receptor ligation in several hematopoietically...

• ESAs administered for more than one of the indicated therapies are to be billed as separate line items

  From:Healthcare Financial Management (Vol. 62, Issue 2) Peer-Reviewed

  Feb. 200879 words Brief article 1180LESAs administered for more than one of the indicated therapies are to be billed as separate line items. That is, ESAs for chemo-induced anemia (EA modifier) are reported as separate line items (e.g., J0881EA); ESAs for...

• Hematopoietic agents and methylphenidate are helpful in cancer-related fatigue

  From:JAAPA-Journal of the American Academy of Physicians Assistants (Vol. 21, Issue 11) Peer-Reviewed

  Nov. 2008261 words Brief article 1030LClinical question What treatments are helpful in improving fatigue associated with cancer and its treatment? Bottom line In patients with cancer-related fatigue, methylphenidate may be helpful. Erythropoiefin is...

• Primitive hematopoietic cells resist HIV-1 infection via p[21.sup.Waf1/Cip1/Sdi1]

  Authors:Jielin Zhang, David T. Scadden, and Clyde S. CrumpackerFrom:Journal of Clinical Investigation (Vol. 117, Issue 2) Peer-Reviewed

  Feb. 20076,332 words Article 1480LHematopoietic stem cells are resistant to HIV-1 infection. Here, we report a novel mechanism by which the cyclin-dependent kinase inhibitor (CKI) p[21.sup.Waf1/Cip1/Sdi1] (p21), a known regulator of stem cell pool size,...

• Effective Jan. 1, 2008, all other claims for ESA administrations will also require the reporting of either the most recent hematocrit or hemoglobin reading

  From:Healthcare Financial Management (Vol. 62, Issue 2) Peer-Reviewed

  Feb. 200852 words Brief article 1290LEffective Jan. 1, 2008, all other claims for ESA administrations will also require the reporting of either the most recent hematocrit or hemoglobin reading. In addition, they should contain one of the following three...

• Blood conservation strategies to reduce the need for red blood cell transfusion in critically ill patients

  Authors:Alan T. Tinmouth, Lauralynn A. McIntyre, and Robert A. FowlerFrom:CMAJ: Canadian Medical Association Journal (Vol. 178, Issue 1) Peer-Reviewed

  Jan. 1, 20086,997 words Report 1970LAbstract Anemia commonly affects critically ill patients. The causes are multifactorial and include acute blood loss, blood loss from diagnostic testing and blunted red blood cell production. Blood transfusions are...

• Coupling of the TCR to Integrin Activation by SLAP- 130/Fyb

  Authors:Erik J. Peterson, Melody L. Woods, Sally A. Dmowski, Geo Derimanov, Martha S. Jordan, Jennifer N. Wu, et al.From:Science (Vol. 293, Issue 5538) Peer-Reviewed

  Sept. 21, 20012,618 words Article SLAP-130/Fyb (SLP-76-associated phosphoprotein or Fyn-binding protein; also known as Fyb/Slap) is a hematopoietic-specific adapter, which associates with and modulates function of SH2-containing leukocyte phosphoprotein...