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    Academic Journals

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• Differential Gene Expression Profile Associated with the Abnormality of Bone Marrow Mesenchymal Stem Cells in Aplastic Anemia

  Authors:Jianping Li, Shaoguang Yang, Shihong Lu, Hui Zhao, Jianming Feng, Wenqian Li, et al.From:PLoS ONE (Vol. 7, Issue 11) Peer-Reviewed

  Nov. 5, 20125,329 words Article 1430LAuthor(s): Jianping Li 1 , 2 , Shaoguang Yang 1 , Shihong Lu 1 , Hui Zhao 3 , Jianming Feng 2 , Wenqian Li 2 , Fengxia Ma 1 , Qian Ren 1 , Bin Liu 1 , Lei Zhang 1 , Yizhou Zheng 1 , Zhong Chao Han 1 , * Introduction...

• Very Small Embryonic-Like Stem Cells Purified from Umbilical Cord Blood Lack Stem Cell Characteristics

  Authors:Ralitza Danova-Alt, Andreas Heider, Dietmar Egger, Michael Cross, and Rudiger AltFrom:PLoS ONE (Vol. 7, Issue 4) Peer-Reviewed

  Apr. 3, 20127,528 words Article 1640LAuthor(s): Ralitza Danova-Alt 1 , 2 , Andreas Heider 2 , Dietmar Egger 1 , Michael Cross 3 , Rüdiger Alt 2 , * Introduction Over the last ten years, there have been various reports of the isolation of putatively...

• Co-Culture of Hematopoietic Stem/Progenitor Cells with Human Osteblasts Favours Mono/Macrophage Differentiation at the Expense of the Erythroid Lineage

  Authors:Simona Salati, Gina Lisignoli, Cristina Manferdini, Valentina Pennucci, Roberta Zini, Elisa Bianchi, et al.From:PLoS ONE (Vol. 8, Issue 1) Peer-Reviewed

  Jan. 22, 20138,091 words Article 1680LAuthor(s): Simona Salati 1 , Gina Lisignoli 2 , 3 , Cristina Manferdini 2 , 3 , Valentina Pennucci 1 , Roberta Zini 1 , Elisa Bianchi 1 , Ruggiero Norfo 1 , Andrea Facchini 2 , 3 , 4 , Sergio Ferrari 5 , Rossella...

• Mesenchymal Stem Cell-Derived Microvesicles Support Ex Vivo Expansion of Cord Blood-Derived [CD34.sup.+] Cells

  Authors:Hui Xie, Li Sun, Liming Zhang, Teng Liu, Li Chen, Aiqi Zhao, et al.From:Stem Cells InternationalPeer-Reviewed

  Annual 20167,998 words Article 1380LMesenchymal stem cells (MSCs) are known to support the characteristic properties of hematopoietic stem and progenitor cells (HSPCs) in the bone marrow hematopoietic microenvironment. MSCs are used in coculture systems...

• A perisinusoidal niche for extramedullary haematopoiesis in the spleen

  Authors:Christopher N. Inra, Bo. O. Zhou, Melih Acar, Malea M. Murphy, James Richardson, Zhiyu Zhao, et al.From:Nature (Vol. 527, Issue 7579) Peer-Reviewed

  Nov. 26, 20156,246 words Report 1410LHaematopoietic stresses mobilize haematopoietic stem cells (HSCs) from the bone marrow to the spleen and induce extramedullary haematopoiesis (EMH). However, the cellular nature of the EMH niche is unknown. Here we...

• Hematopoietic stem and progenitor cells can be enriched by implanting biomaterial into spatium intermusculare

  Authors:Jia-Bei Tong, Xiao-Yun Wu, Ge-Liuchang Jia, Kui-Jun Zhao, Shi-Li Wang, and Zhi-Jie MaFrom:BioMed Research InternationalPeer-Reviewed

  Annual 20155,279 words Report 1300LHematopoietic stem and progenitor cells (HSPCs) have been used successfully to treat patients with cancer and disorders of the blood and immune systems. In this study, we tried to enrich HSPCs by implanting biomaterials...

• EDAG promotes the expansion and survival of human CD34.sup.+ cells

  Authors:Ke Zhao, Wei-Wei Zheng, Xiao-Ming Dong, Rong-Hua Yin, Rui Gao, Xiu Li, et al.From:PLoS ONE (Vol. 13, Issue 1) Peer-Reviewed

  Jan. 11, 20186,020 words Article 1300LAuthor(s): Ke Zhao 1, Wei-Wei Zheng 1, Xiao-Ming Dong 2, Rong-Hua Yin 1, Rui Gao 1, Xiu Li 3, Jin-Fang Liu 4, Yi-Qun Zhan 1, Miao Yu 1, Hui Chen 1, Chang-Hui Ge 1, Hong-Mei Ning 5,*, Xiao-Ming Yang 1,2,*, Chang-Yan Li...

• Development of Human Mast Cells from Hematopoietic Stem Cells within a 3D Collagen Matrix: Effect of Stem Cell Media on Mast Cell Generation

  Authors:Tahereh Derakhshan, Rudra Bhowmick, Jerry W. Ritchey, and Heather Gappa-FahlenkampFrom:Stem Cells International (Vol. 2018) Peer-Reviewed

  Annual 20188,908 words Article 1430LMast cells (MCs) arise from hematopoietic stem cells (HSCs) that mature within vascularized tissues. Fibroblasts and endothelial cells (ECs) play a role in the maturation of HSCs in the tissues. Due to difficulties in...

• Dyskeratosis Congenita.

  Authors:Eric T. Stoopler and Rabie M. ShantiFrom:Mayo Clinic Proceedings (Vol. 94, Issue 9) Peer-Reviewed

  Sept. 2019576 words Article 2150LA 14-year-old girl with dyskeratosis congenita (DC) was evaluated for widespread symptomatic oral lesions that developed shortly after undergoing allogeneic hematopoietic stem cell transplant (allo-HSCT) at the age of 1...

• Plasticity of cells and ex vivo production of red blood cells

  Authors:Takashi Hiroyama, Kenichi Miharada, Ryo Kurita, and Yukio NakamuraFrom:Stem Cells InternationalPeer-Reviewed

  Annual 20115,068 words Report 1550LThe supply of transfusable red blood cells (RBCs) is not sufficient in many countries. If transfusable RBCs could be produced abundantly from certain resources, it would be very useful. Our group has developed a method...

• Comparison of signaling pathways gene expression in [CD34.sup.-] umbilical cord blood and bone marrow stem cells

  Authors:Rafal Stojko, Monika Bojdys-Szyndlar, Agnieszka Drosdzol-Cop, Andrzej Madej, and Krzysztof WilkFrom:Stem Cells InternationalPeer-Reviewed

  Annual 201510,143 words Article 1490LThe aim of the study was to compare the biological activity of the total pool of genes in [CD34.sup.-] umbilical cord blood and bone marrow stem cells and to search for the differences in signaling pathway gene...

• Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy

  Authors:Alejandra Sanjuan-Pla, Iain C. Macaulay, Christina T. Jensen, Petter S. Woll, Tiago C. Luis, Adam Mead, et al.From:Nature (Vol. 502, Issue 7470) Peer-Reviewed

  Oct. 10, 20135,496 words Letter to the editor 1530LThe blood system is maintained by a small pool of haematopoietic stem cells (HSCs), which are required and sufficient for replenishing all human blood cell lineages at millions of cells per second throughout life....

• Transglutaminase Type 2 is Involved in the Hematopoietic Stem Cells Homeostasis.

  Authors:S. Oliverio, J. S. O. Beltran, L. Occhigrossi, V. Bordoni, C. Agrati, M. D'Eletto, et al.From:Biochemistry (Moscow) (Vol. 85, Issue 10) Peer-Reviewed

  Oct. 20205,667 words Report 1520LType 2 transglutaminase (TG2) is a multifunctional protein involved in various biological processes playing a key regulatory role in cell homeostasis such as cell death and autophagy. New evidence is emerging that...

• Erythropoietin Couples Hematopoiesis with Bone Formation

  Authors:Yusuke Shiozawa, Younghun Jung, Anne M. Ziegler, Elisabeth A. Pedersen, Jianhua Wang, Zhuo Wang, et al.From:PLoS ONE (Vol. 5, Issue 5) Peer-Reviewed

  May 27, 20107,930 words Article 1490LBackground It is well established that bleeding activates the hematopoietic system to regenerate the loss of mature blood elements. We have shown that hematopoietic stem cells (HSCs) isolated from animals challenged...

• Promiscuous Expression of H2B-GFP Transgene in Hematopoietic Stem Cells

  Authors:Grant A. Challen and Margaret A. GoodellFrom:PLoS ONE (Vol. 3, Issue 6) Peer-Reviewed

  June 4, 20086,855 words Article 1630LBackground The study of adult stem cells relies on the ability to isolate them using complex combinations of markers for flow cytometry. A recent study has used a tetracycline-regulatable H2B-GFP transgenic mouse...

• Separate Developmental Programs for HLA-A and -B Cell Surface Expression during Differentiation from Embryonic Stem Cells to Lymphocytes, Adipocytes and Osteoblasts

  Authors:Hardee J. Sabir, Jan O. Nehlin, Diyako Qanie, Linda Harkness, Tatyana A. Prokhorova, Blagoy Blagoev, et al.From:PLoS ONE (Vol. 8, Issue 1) Peer-Reviewed

  Jan. 18, 20137,171 words Article 1650LA major problem of allogeneic stem cell therapy is immunologically mediated graft rejection. HLA class I A, B, and Cw antigens are crucial factors, but little is known of their respective expression on stem cells and...

• Prognostic Significance of Initial Serum Albumin and 24 Hour Daily Protein Excretion before Treatment in Multiple Myeloma

  Authors:Jia-Hong Chen, Shun-Neng Hsu, Tzu-Chuan Huang, Yi-Ying Wu, Chin Lin, Ping-Ying Chang, et al.From:PLoS ONE (Vol. 10, Issue 6) Peer-Reviewed

  June 8, 20154,187 words Article 1460LRenal failure is a common morbidity in multiple myeloma (MM). Although proteinuria has been increasingly reported in malignancies, it is not routinely used to refine risk estimates of survival outcomes in patients with...

• The Endoplasmic Reticulum Chaperone Protein GRP94 Is Required for Maintaining Hematopoietic Stem Cell Interactions with the Adult Bone Marrow Niche

  Authors:Biquan Luo, Ben S. Lam, Sung Hyung Lee, Shiuan Wey, Hui Zhou, Miao Wang, et al.From:PLoS ONE (Vol. 6, Issue 5) Peer-Reviewed

  May 24, 20118,470 words Article 1530LHematopoietic stem cell (HSC) homeostasis in the adult bone marrow (BM) is regulated by both intrinsic gene expression products and interactions with extrinsic factors in the HSC niche. GRP94, an endoplasmic reticulum...

• The HOXB4 Homeoprotein Promotes the Ex Vivo Enrichment of Functional Human Embryonic Stem Cell-Derived NK Cells

  Authors:Aniya Larbi, Jean-Marc Gombert, Celine Auvray, Bruno l'Homme, Aurelie Magniez, Olivier Feraud, et al.From:PLoS ONE (Vol. 7, Issue 6) Peer-Reviewed

  June 27, 20127,555 words Article 1670LHuman embryonic stem cells (hESCs) can be induced to differentiate into blood cells using either co-culture with stromal cells or following human embryoid bodies (hEBs) formation. It is now well established that the...

• Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms

  Authors:Heather A Himburg, Phuong L Doan, Mamle Quarmyne, Xiao Yan, Joshua Sasine, Liman Zhao, et al.From:Nature Medicine (Vol. 23, Issue 1) Peer-Reviewed

  Jan. 201711,399 words Report 1610LThe role of osteolineage cells in regulating hematopoietic stem cell (HSC) regeneration following myelosuppression is not well understood. Here we show that deletion of the pro-apoptotic genes Bak and Bax in osterix...