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    Academic Journals

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• Select Response to Janiszewski et al

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  Response to Janiszewski et al

  Authors:K.N. Manolopoulos, F. Karpe, and K.N. FraynFrom:International Journal of Obesity (Vol. 34, Issue 6) Peer-Reviewed

  June 2010314 words Brief article, Lette... 1570LWe thank Dr Janiszewski and Dr Kuk for their thoughtful comments. (1) These comments highlight the complexity of the relationships between different fat depots and metabolic health. The protective effects of the...
• Select Growth retardation in children with epilepsy on the ketogenic diet: A retrospective chart review. (Research and Professional Briefs)

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  Growth retardation in children with epilepsy on the ketogenic diet: A retrospective chart review. (Research and Professional Briefs)

  Authors:Shelley Williams, Carlota Basualdo-Hammond, Rosalind Curtis, and Reinhard SchullerFrom:Journal of the American Dietetic Association (Vol. 102, Issue 3) Peer-Reviewed

  Mar. 20021,874 words Abstract, Bibliograp... Johns Hopkins Medical Center, Baltimore, Md, and the Mayo Clinic, Rochester, Minn, developed the classic ketogenic diet in the 1920s for children with intractable epilepsy (1,2) and the diet has resurfaced as a...
• Select Use of the traditional ketogenic diet for treatment of intractable epilepsy

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  Use of the traditional ketogenic diet for treatment of intractable epilepsy

  Author:Alice T. GaschFrom:Journal of the American Dietetic Association (Vol. 90, Issue 10) Peer-Reviewed

  Oct. 19901,796 words Article The ketogenic diet provides almost all calories from fat, and has been used to treat epilepsy. From 1922 to 1944, the ketogenic diet was found to be effective in completely controlling seizures in 230 patients at the...
• Select Ondansetron ameliorates depression associated with obesity in high-fat diet fed experimental mice: An investigation-based on the behavioral, biochemical, and molecular approach

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  Ondansetron ameliorates depression associated with obesity in high-fat diet fed experimental mice: An investigation-based on the behavioral, biochemical, and molecular approach

  Authors:Yeshwant Kurhe and Radhakrishnan MaheshFrom:Indian Journal of Pharmacology (Vol. 49, Issue 4) Peer-Reviewed

  July-August 20173,420 words Report 1880LByline: Yeshwant. Kurhe, Radhakrishnan. Mahesh INTRODUCTION: Obesity is an important risk factor for depression as more than half of the obese population is susceptible for depression at double rate. Our earlier...
• Select Hypoxia-induced intrauterine growth restriction increases the susceptibility of rats to high-fat diet--induced metabolic syndrome

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  Hypoxia-induced intrauterine growth restriction increases the susceptibility of rats to high-fat diet--induced metabolic syndrome

  Authors:Christian F. Rueda-Clausen, Vernon W. Dolinsky, Jude S. Morton, Spencer D. Proctor, Jason R.B. Dyck, and Sandra T. DavidgeFrom:Diabetes (Vol. 60, Issue 2) Peer-Reviewed

  Feb. 20116,191 words Report 1560LOBJECTIVE--It is recognized that there is a remarkable variability in the systemic response to high-fat (HF) diets that cannot be completely explained by genetic factors. In addition, pregnancy complications leading to...
• Select The cardiovascular health of the nation--should we be advocating a low-carbohydrate high-fat diet?

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  The cardiovascular health of the nation--should we be advocating a low-carbohydrate high-fat diet?

  From:SAMJ South African Medical Journal (Vol. 102, Issue 9) Peer-Reviewed

  Sept. 20121,177 words Editorial 1830LA spate of articles in the lay press have advocated a low-carbohydrate high-fat diet for cardiovascular health, questioning 'What's cholesterol got to do with it?' and whether cholesterol-lowering drugs, particularly...
• Select Altered gastric vagal mechanosensitivity in diet-induced obesity persists on return to normal chow and is accompanied by increased food intake

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  Altered gastric vagal mechanosensitivity in diet-induced obesity persists on return to normal chow and is accompanied by increased food intake

  Authors:S.J. Kentish, T.A. O'Donnell, C.L. Frisby, H. Li, G.A. Wittert, and A.J. PageFrom:International Journal of Obesity (Vol. 38, Issue 5) Peer-Reviewed

  May 20145,500 words Report 1710LBACKGROUND AND AIMS: Gastric vagal afferents convey satiety signals in response to mechanical stimuli. The sensitivity of these afferents is decreased in diet-induced obesity. Leptin, secreted from gastric epithelial...
• Select Fatty acid synthesis and generation of glycerol-3-phosphate in brown adipose tissue from rats fed a cafeteria diet

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  Fatty acid synthesis and generation of glycerol-3-phosphate in brown adipose tissue from rats fed a cafeteria diet

  Authors:Valeria E. Chaves, Danubia Frasson, Maria E.S. Martins-Santos, Luiz C.C. Navegantes, Victor D. Galban, Maria A.R. Garofalo, et al.From:Canadian Journal of Physiology and Pharmacology (Vol. 86, Issue 7) Peer-Reviewed

  July 20084,854 words Article 1620LAbstract: In vivo fatty acid synthesis and the pathways of glycerol-3-phosphate (G3P) production were investigated in brown adipose tissue (BAT) from rats fed a cafeteria diet for 3 weeks. In spite of BAT activation,...
• Select Blocking high-fat diet-induced obesity, insulin resistance and fatty liver by overexpression of Il-13 gene in mice

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  Blocking high-fat diet-induced obesity, insulin resistance and fatty liver by overexpression of Il-13 gene in mice

  Authors:P. Darkhal, M. Gao, Y. Ma, and D. LiuFrom:International Journal of Obesity (Vol. 39, Issue 8) Peer-Reviewed

  Aug. 20154,764 words Report 1760LOBJECTIVES: The objective of this study was to assess the activity of anti-inflammatory cytokine IL-13 (interleukin-13) in blocking high-fat diet-induced obesity and obesity-associated insulin resistance and liver...
• Select Weight loss surgery improves the metabolic status in an obese rat model but does not affect bladder fibrosis associated with high fat diet feeding

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  Weight loss surgery improves the metabolic status in an obese rat model but does not affect bladder fibrosis associated with high fat diet feeding

  Authors:A. Oberbach, N. Schlichting, M. Heinrich, S. Lehmann, H. Till, F.W. Mohr, et al.From:International Journal of Obesity (Vol. 38, Issue 8) Peer-Reviewed

  Aug. 20144,553 words Report 1600LBACKGROUND: Bladder dysfunction has one of the highest prevalences as a comorbidity of obesity in industrialized countries. The aetiopathogenesis of obesity-associated bladder dysfunction is still obscure, but there is...
• Select Effect of Seyoeum on Obesity, Insulin Resistance, and Nonalcoholic Fatty Liver Disease of High-Fat Diet-Fed C57BL/6 Mice

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  Effect of Seyoeum on Obesity, Insulin Resistance, and Nonalcoholic Fatty Liver Disease of High-Fat Diet-Fed C57BL/6 Mice

  Authors:Hyun-Young Na, Mi Hyeon Seol, Mia Kim, and Byung-Cheol LeeFrom:Evidence - Based Complementary and Alternative Medicine (Vol. 2017) Peer-Reviewed

  Annual 20175,146 words Report 1430LBackground. This study was performed to evaluate the effect of Seyoeum (SYE), a novel herbal meal replacement, on insulin resistance and nonalcoholic fatty liver disease (NAFLD) in obese mice fed with a high-fat diet...
• Select The Effects of Exercise Training and High Triglyceride Diet in an Estrogen Depleted Rat Model: The Role of the Heme Oxygenase System and Inflammatory Processes in Cardiovascular Risk

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  The Effects of Exercise Training and High Triglyceride Diet in an Estrogen Depleted Rat Model: The Role of the Heme Oxygenase System and Inflammatory Processes in Cardiovascular Risk

  Authors:Csaba Varga, Medea Veszelka, Krisztina Kupai, Denise Borzsei, Zoltan Deim, Renata Szabo, et al.From:Journal of Sports Science and Medicine (Vol. 17, Issue 4) Peer-Reviewed

  Dec. 20185,672 words Report 1420LCardiovascular morbidity and mortality of premenopausal women are significantly lower compared to men of similar age. However, this protective effect evidently decreases after the onset of menopause. We hypothesized...
• Select Pruritic rash on chest and back: Was a recent change in diet to blame for this patient's rash?

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  Pruritic rash on chest and back: Was a recent change in diet to blame for this patient's rash?

  Authors:Daniel Croom, Thomas Barlow, and Thomas LandersFrom:Journal of Family Practice (Vol. 68, Issue 2) Peer-Reviewed

  Mar. 2019932 words Article 1700LA 26-YEAR-OLD WOMAN presented to our clinic with pruritic, hyperpigmented, symmetric edematous plaques on her upper flank, chest, and lower back (FIGURE) 3 weeks after starting a strict ketogenic (high fat/low...
• Select The role of the herbal medicines, Rehmanniae radix, Citrus unshiu peel, and Poria cocos wolf, in high-fat diet-induced obesity

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  The role of the herbal medicines, Rehmanniae radix, Citrus unshiu peel, and Poria cocos wolf, in high-fat diet-induced obesity

  Authors:Min Kwon, Jung Kim, Eun Lim, Yun Kim, Hyungwoo Kim, Myeong Jung, et al.From:Pharmacognosy Magazine (Vol. 15, Issue 63) Peer-Reviewed

  July-September 20193,503 words Report 1710LByline: Min. Kwon, Jung. Kim, Eun. Lim, Yun. Kim, Hyungwoo. Kim, Myeong. Jung, Byung. Kim Background: Herbal medicine has been used for the treatment of obesity. Obesity is a very common global health problem, and it...
• Select Altered hypothalamic function in diet-induced obesity

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  Altered hypothalamic function in diet-induced obesity

  Authors:L.A. Velloso and M.W. SchwartzFrom:International Journal of Obesity (Vol. 35, Issue 12) Peer-Reviewed

  Dec. 20118,391 words Report 2220LEnergy homeostasis involves a complex network of hypothalamic and extra-hypothalamic neurons that transduce hormonal, nutrient and neuronal signals into responses that ultimately match caloric intake to energy...
• Select Nrf2 represses FGF21 during long-term high-fat diet--induced obesity in mice

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  Nrf2 represses FGF21 during long-term high-fat diet--induced obesity in mice

  Authors:Dionysios V. Chartoumpekis, Panos G. Ziros, Agathoklis I. Psyrogiannis, Athanasios G. Papavassiliou, Venetsana E. Kyriazopoulou, Gerasimos P. Sykiotis, et al.From:Diabetes (Vol. 60, Issue 10) Peer-Reviewed

  Oct. 20115,684 words Report 1420LOBJECTIVE--Obesity is characterized by chronic oxidative stress. Fibroblast growth factor 21 (FGF21) has recently been identified as a novel hormone that regulates metabolism. NFE2-related factor 2 (Nrf2) is a...
• Select Siah2 modulates sex-dependent metabolic and inflammatory responses in adipose tissue to a high-fat diet challenge.

  17

  Siah2 modulates sex-dependent metabolic and inflammatory responses in adipose tissue to a high-fat diet challenge.

  Authors:Sujoy Ghosh, Jessica L. Taylor, Tamra M. Mendoza, Thanh Dang, David H. Burk, Yongmei Yu, et al.From:Biology of Sex Differences (Vol. 10, Issue 1) Peer-Reviewed

  Apr. 15, 20197,705 words Report 1720LBackground The obesity-related risk of developing metabolic syndrome is higher in males than in females of reproductive age, likely due to estrogen-mediated reduced adipose tissue inflammation and fibrosis with...
• Select Roles of leptin in the recovery of muscle and bone by reloading after mechanical unloading in high fat diet-fed obese mice.

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  Roles of leptin in the recovery of muscle and bone by reloading after mechanical unloading in high fat diet-fed obese mice.

  Authors:Naoyuki Kawao, Masayoshi Ishida, and Hiroshi KajiFrom:PLoS ONE (Vol. 14, Issue 10) Peer-Reviewed

  Oct. 24, 20197,923 words Report 1470LMuscle and bone masses are elevated by the increased mechanical stress associated with body weight gain in obesity. However, the mechanisms by which obesity affects muscle and bone remain unclear. We herein investigated...
• Select Effect of high-fat diet upon inflammatory markers and aortic stiffening in mice

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  Effect of high-fat diet upon inflammatory markers and aortic stiffening in mice

  Authors:Andre Bento Chaves Santana, Thais Cristina de Souza Oliveira, Barbara Lobo Bianconi, Valerio Garrone Barauna, Ed Wilson Cavalcante Oliveira Santos, Tatiana P. Alves, et al.From:BioMed Research InternationalPeer-Reviewed

  Annual 20145,827 words Report 1380LChanges in lifestyle such as increase in high-fat food consumption are an important cause for vascular diseases. The present study aimed to investigate the involvement of ACE and TGF-[beta] in the aorta stiffness...
• Select Differential microRNA response to a high-cholesterol, high-fat diet in livers of low and high LDL-C baboons

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  Differential microRNA response to a high-cholesterol, high-fat diet in livers of low and high LDL-C baboons

  Authors:Genesio M Karere, Jeremy P Glenn, John L VandeBerg, and Laura A CoxFrom:BMC Genomics (Vol. 13, Issue 1) Peer-Reviewed

  July 18, 201210,739 words Report 1460LBackground Dysregulation of microRNA (miRNA) expression has been implicated in molecular genetic events leading to the progression and development of atherosclerosis. We hypothesized that miRNA expression profiles...