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Academic Journals
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From:Journal of the American Dietetic Association (Vol. 102, Issue 3) Peer-ReviewedJohns Hopkins Medical Center, Baltimore, Md, and the Mayo Clinic, Rochester, Minn, developed the classic ketogenic diet in the 1920s for children with intractable epilepsy (1,2) and the diet has resurfaced as a...
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From:Journal of the American Dietetic Association (Vol. 90, Issue 10) Peer-ReviewedThe ketogenic diet provides almost all calories from fat, and has been used to treat epilepsy. From 1922 to 1944, the ketogenic diet was found to be effective in completely controlling seizures in 230 patients at the...
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From:Indian Journal of Pharmacology (Vol. 49, Issue 4) Peer-ReviewedByline: Yeshwant. Kurhe, Radhakrishnan. Mahesh INTRODUCTION: Obesity is an important risk factor for depression as more than half of the obese population is susceptible for depression at double rate. Our earlier...
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From:Diabetes (Vol. 60, Issue 2) Peer-ReviewedOBJECTIVE--It is recognized that there is a remarkable variability in the systemic response to high-fat (HF) diets that cannot be completely explained by genetic factors. In addition, pregnancy complications leading to...
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From:Canadian Journal of Physiology and Pharmacology (Vol. 86, Issue 7) Peer-ReviewedAbstract: In vivo fatty acid synthesis and the pathways of glycerol-3-phosphate (G3P) production were investigated in brown adipose tissue (BAT) from rats fed a cafeteria diet for 3 weeks. In spite of BAT activation,...
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From:Evidence - Based Complementary and Alternative Medicine (Vol. 2017) Peer-ReviewedBackground. This study was performed to evaluate the effect of Seyoeum (SYE), a novel herbal meal replacement, on insulin resistance and nonalcoholic fatty liver disease (NAFLD) in obese mice fed with a high-fat diet...
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From:Journal of Family Practice (Vol. 68, Issue 2) Peer-ReviewedA 26-YEAR-OLD WOMAN presented to our clinic with pruritic, hyperpigmented, symmetric edematous plaques on her upper flank, chest, and lower back (FIGURE) 3 weeks after starting a strict ketogenic (high fat/low...
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From:Diabetes (Vol. 60, Issue 10) Peer-ReviewedOBJECTIVE--Obesity is characterized by chronic oxidative stress. Fibroblast growth factor 21 (FGF21) has recently been identified as a novel hormone that regulates metabolism. NFE2-related factor 2 (Nrf2) is a...
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From:PLoS ONE (Vol. 14, Issue 10) Peer-ReviewedMuscle and bone masses are elevated by the increased mechanical stress associated with body weight gain in obesity. However, the mechanisms by which obesity affects muscle and bone remain unclear. We herein investigated...
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From:BioMed Research InternationalPeer-ReviewedChanges in lifestyle such as increase in high-fat food consumption are an important cause for vascular diseases. The present study aimed to investigate the involvement of ACE and TGF-[beta] in the aorta stiffness...
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From:PLoS ONE (Vol. 12, Issue 2) Peer-ReviewedFactors affecting contribution of spontaneous physical activity (SPA; activity associated with everyday tasks) to energy balance of humans are not well understood, as it is not clear whether low activity is related to...
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From:Environmental Health Perspectives (Vol. 117, Issue 6) Peer-ReviewedBACKGROUND: Developmental exposure to a wide variety of developmental neurotoxicants, including organophosphate pesticides, evokes late-emerging and persistent abnormalities in acetylcholine (ACh) systems. We are...
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From:Canadian Journal of Physiology and Pharmacology (Vol. 89, Issue 4) Peer-ReviewedTo determine whether short-term consumption of a moderately high-fat diet (MHFD) affects nitric oxide (NO) production, the concentration of stable NO metabolites (NOx) in urine and plasma of rats fed a MHFD (15.6 %g...
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From:Maternal and Child Health Journal (Vol. 17, Issue 2) Peer-ReviewedTo examine the association between maternal prepregnancy obesity and cognitive test scores of children at early primary school age. A descriptive observational design was used. Study subjects consist of 3,412 US...
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From:Diabetes (Vol. 55, Issue 1) Peer-ReviewedNeuropeptide Y receptors are critical regulators of energy homeostasis, but the functional interactions and relative contributions of Y receptors and the environment in this process are unknown. We measured the effects...
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From:European Journal of Clinical Nutrition (Vol. 71, Issue 11) Peer-ReviewedBackground/Objectives: Abnormalities in lipoprotein profiles (size, distribution and concentration) play an important role in the pathobiology of atherosclerosis and coronary artery disease. Dietary fat, among other...
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From:PLoS ONE (Vol. 17, Issue 8) Peer-ReviewedNonalcoholic fatty liver disease (NALFD), characterized by an abnormal accumulation of triglycerides in hepatocytes, is closely linked to insulin resistance, metabolic syndrome, and changes in lipogenesis in the liver....
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From:PLoS ONE (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Paola Gauffin Cano, Arlette Santacruz, Ángela Moya, Yolanda Sanz * Introduction Obesity is considered a major health issue due to its increasing prevalence and associated co-morbidities (e.g. type 2...
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From:PLoS ONE (Vol. 12, Issue 10) Peer-ReviewedPrevious studies confirmed that dietary supplements of fish oil and krill oil can alleviate obesity in mice, but the underlying mechanism remains unclear. This study aims to discern whether oil treatment change the...
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From:Diabetes (Vol. 57, Issue 9) Peer-ReviewedOBJECTIVE--The G-protein--coupled receptor GPR40 is expressed in pancreatic [beta]-cells and is activated by long-chain fatty acids. Gene deletion studies have shown that GPR40 mediates, at least in part, fatty...