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- 1,151
Academic Journals
- 1,151
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From:Expert Review of Ophthalmology (Vol. 8, Issue 5) Peer-ReviewedAuthor(s): Dhiren Bujarborua [*] 1 , Shyamanga Borooah 2 , Baljean Dhillon 3 Keywords : HPA; glucocorticoids; central serous chorioretinopathy; stress; sympathetic nervous system Central serous...
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From:Diabetes (Vol. 58, Issue 12) Peer-ReviewedOBJECTIVE--The goal of this study was to investigate whether the effects of common genetic variants associated with fasting glucose in adults are detectable in healthy children. RESEARCH DESIGN AND METHODS--Single...
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From:Science (Vol. 308, Issue 5725) Peer-ReviewedThe peptide vasopressin (antidiuretic hormone) is critical for maintaining fluid homeostasis. Its receptor, V2R, is Located at the surface of epithelial cells lining the kidney's collecting duct. Receptor activation...
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From:PLoS ONE (Vol. 7, Issue 12) Peer-ReviewedAuthor(s): Maria Gisella Cavallo 2 , Federica Sentinelli 1 , Ilaria Barchetta 2 , Carmine Costantino 2 , Michela Incani 1 , Laura Perra 1 , Danila Capoccia 3 , Stefano Romeo 1 , 4 , Efisio Cossu 1 , Frida Leonetti 3 ,...
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From:PLoS ONE (Vol. 8, Issue 8) Peer-ReviewedAuthor(s): Sapna Puri 1, Alejandro García-Núñez 2, Matthias Hebrok 1, David A. Cano 2,* Introduction The role of hypoxia in ß-cell formation and function has recently gained considerable interest [1]. Central to...
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From:AIDS Research and TreatmentPeer-ReviewedAim. We determined the prevalence of anaemia and evaluated markers of iron homeostasis in a cohort of HIV patients. Methods. A comparative cross-sectional study on 319 participants was carried out at the Tamale Teaching...
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From:Nature (Vol. 528, Issue 7581) Peer-ReviewedSomatic stem cells maintain tissue homeostasis by dynamically adjusting proliferation and differentiation in response to stress and metabolic cues. Here we identify [Ca.sup.2+] signalling as a central regulator of...
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From:Nature Medicine (Vol. 21, Issue 8) Peer-ReviewedSkeletal muscle mass, function, and repair capacity all progressively decline with aging, restricting mobility, voluntary function, and quality of life. Skeletal muscle repair is facilitated by a population of dedicated...
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From:Applied Physiology, Nutrition, and Metabolism (Vol. 42, Issue 6) Peer-ReviewedTre-2/USP6, BUB2, cdc16 domain family, member 1 (TBC1D1), a Rab-GTPase activating protein, is a paralogue of AS160, and has been implicated in the canonical insulin-signaling cascade in peripheral tissues. More...
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From:Journal of Clinical Investigation (Vol. 127, Issue 6) Peer-ReviewedGenetic variants at the solute carrier family 39 member 8 (SLC39A8) gene locus are associated with the regulation of wholeblood manganese (Mn) and multiple physiological traits. SLC39A8 encodes ZIP8, a divalent metal...
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From:BioMed Research InternationalPeer-ReviewedRats fed calcium-deprived diet develop osteoporosis due to enhanced bone resorption, secondary to parathyroid overactivity resulting from nutritional hypocalcemia. Therefore, rats provide a good experimental animal...
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From:Journal of Clinical Investigation (Vol. 124, Issue 2) Peer-ReviewedThe mechanisms that regulate the strength of synaptic transmission and intrinsic neuronal excitability are well characterized; however, the mechanisms that promote disease-causing neural network dysfunction are poorly...
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From:Physiological Reviews (Vol. 85, Issue 4) Peer-Revieweddoi:10.1152/physrev.00015.2004.--Our knowledge of the physiological systems controlling energy homeostasis has increased dramatically over the last decade. The roles of peripheral signals from adipose tissue, pancreas,...
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From:Nature (Vol. 513, Issue 7516) Peer-ReviewedReceptor interacting protein kinase 1 (RIPK1) has an essential role in the signalling triggered by death receptors and pattern recognition receptors (1,2). RIPK1 is believed to function as a node driving...
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From:PLoS ONE (Vol. 13, Issue 2) Peer-ReviewedAuthor(s): Lin Cheng 1,2, Lucy J. Wong 2,3, Naihong Yan 2,4, Richard C. Han 2, Honghua Yu 2, Chenying Guo 2, Khulan Batsuuri 2, Aniket Zinzuwadia 2, Ryan Guan 2, Kin-Sang Cho 2, Dong Feng Chen 2,* Introduction...
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From:International Journal of Clinical and Experimental Physiology (Vol. 4, Issue 3) Peer-ReviewedByline: Udensi. Udensi, Paul. Tchounwou Potassium is the most abundant cation in the intracellular fluid, and it plays a vital role in the maintenance of normal cell functions. Thus, potassium homeostasis across the...
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From:Oxidative Medicine and Cellular Longevity (Vol. 2016) Peer-ReviewedReactive oxygen species (ROS) and their products are components of cell signaling pathways and play important roles in cellular physiology and pathophysiology. Under physiological conditions, cells control ROS levels by...
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From:Oxidative Medicine and Cellular Longevity (Vol. 2016) Peer-ReviewedThe widely used herbicide atrazine (ATR) can cause many adverse effects including immunotoxicity, but the underlying mechanisms are not fully understood. The current study investigated the role of oxidative stress and...
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From:Diabetes (Vol. 45, Issue 11) Peer-Reviewed3T3-L1 adipocytes represent an established physiological model for studying glucose uptake and storage. Overexpression of epidermal growth factor (EGF) receptors in these cells (20O,000-250,000 receptors per cell)...
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From:Canadian Journal of Physiology and Pharmacology (Vol. 96, Issue 7) Peer-ReviewedThe interaction between vascular endothelial cells (VECs) and vascular smooth muscle cells (VSMCs) plays an important role in the modulation of vascular tone. There is, however, no information on whether direct physical...