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    Academic Journals

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• Oxime ether lipids containing hydroxylated head groups are more superior siRNA delivery agents than their nonhydroxylated counterparts

  Authors:Kshitij Gupta, Stephanie J Mattingly, Ralph J Knipp, Kirill A Afonin, Mathias Viard, Joseph T Bergman, et al.From:Nanomedicine (Vol. 10, Issue 18) Peer-Reviewed

  Sept. 20157,521 words Report 1680LAuthor(s): Kshitij Gupta aff1 , Stephanie J Mattingly aff2 , Ralph J Knipp aff2 , Kirill A Afonin aff1 aff3 , Mathias Viard aff4 aff5 , Joseph T Bergman aff1 , Marissa Stepler aff1 , Michael H Nantz aff2 , Anu Puri [**]...

• Cloning and Characterization of Genes Involved in Nostoxanthin Biosynthesis of Sphingomonas elodea ATCC 31461

  Authors:Liang Zhu, Xuechang Wu, Ou Li, Chaodong Qian, and Haichun GaoFrom:PLoS ONE (Vol. 7, Issue 4) Peer-Reviewed

  Apr. 11, 20125,281 words Article 1350LAuthor(s): Liang Zhu, Xuechang Wu * , Ou Li, Chaodong Qian, Haichun Gao Introduction Carotenoids are isoprenoid pigments that are widely distributed in nature [1]. They can be synthesized by all known phototrophic...

• The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1[alpha] prolyl hydroxylation by regulating cellular iron levels

  Authors:Anna L Miles, Stephen P Burr, Guinevere L Grice, and James A NathanFrom:eLife (Vol. 6) Peer-Reviewed

  Mar. 15, 201718,291 words Report 1510LHypoxia Inducible transcription Factors (HIFs) are principally regulated by the 2-oxoglutarate and Iron(II) prolyl hydroxylase (PHD) enzymes, which hydroxylate the HIF[alpha] subunit, facilitating its...

• Alcohol can impair measurement. (Atmospheric Chemistry)

  From:Science (Vol. 296, Issue 5566) Peer-Reviewed

  Apr. 12, 2002194 words Brief article Oxidation reactions involving hydroxyl radical (OH) and hydrogen dioxide (H[O.sub.2])--collectively known as H[O.sub.x]--play an important role in atmospheric chemistry by destroying many pollutants. However, because...

• Functional Characterization of a First Avian Cytochrome P450 of the CYP2D Subfamily (CYP2D49)

  Authors:Hua Cai, Jun Jiang, Qi Yang, Qingmei Chen, and Yiqun DengFrom:PLoS ONE (Vol. 7, Issue 6) Peer-Reviewed

  June 4, 20129,035 words Article 1410LAuthor(s): Hua Cai, Jun Jiang, Qi Yang, Qingmei Chen, Yiqun Deng * Introduction Cytochrome P450 monooxygenases (CYPs) are heme-containing enzymes that are responsible for metabolizing numerous endogenous and...

• Drug-Induced Reactivation of Apoptosis Abrogates HIV-1 Infection

  Authors:Hartmut M. Hanauske-Abel, Deepti Saxena, Paul E. Palumbo, Axel-Rainer Hanauske, Augusto D. Luchessi, Tavane D. Cambiaghi, et al.From:PLoS ONE (Vol. 8, Issue 9) Peer-Reviewed

  Sept. 23, 201320,316 words Article 1500LAuthor(s): Hartmut M. Hanauske-Abel 1,2,3,*, Deepti Saxena 2, Paul E. Palumbo 2, Axel-Rainer Hanauske 4, Augusto D. Luchessi 1, Tavane D. Cambiaghi 1, Mainul Hoque 1, Michael Spino 5,6, Darlene D'Alliessi Gandolfi 7,...

• Endothelin-1 Inhibits Prolyl Hydroxylase Domain 2 to Activate Hypoxia-Inducible Factor-1[alpha] in Melanoma Cells

  Authors:Francesca Spinella, Laura Rosano, Martina Del Duca, Valeriana Di Castro, Maria Rita Nicotra, Pier Giorgio Natali, et al.From:PLoS ONE (Vol. 5, Issue 6) Peer-Reviewed

  June 21, 20108,206 words Article 1540LBackground The endothelin B receptor (ET.sub.B R) promotes tumorigenesis and melanoma progression through activation by endothelin (ET)-1, thus representing a promising therapeutic target. The stability of...

• A direct, one-step enzymatic hydroxylation of benzene to phenol

  Author:Gerald OndreyFrom:Chemical Engineering (Vol. 120, Issue 9) Peer-Reviewed

  Sept. 2013260 words Brief article 1530LThe selective, one-step biocatalytic hydroxylation of benzene to phenol--at ambient pressure and temperature--has been demonstrated by professors Yoshihito Watanabe and Osamu Shoji at Nagoya University (Nagoya, Japan;...

• Stereoselective benzylic hydroxylation of ethylbenzene and propylbenzene using the mycelia of Aspergillus flavus MTCC-1783 and MTCC-1884

  Authors:Saroj Yadav, R.S.S. Yadav, and K.D.S. YadavFrom:Canadian Journal of Chemistry (Vol. 90, Issue 7) Peer-Reviewed

  July 20122,322 words Report 1830LThe aim of this study was to provide syntheses of optically pure (R)-l-phenylethanol and (R)-1-phenylpropanol from ethylbenzene and propylbenzene, respectively, using the fungal mycelia of new fungal species, namely...

• Current understanding of the molecular actions of vitamin D

  Authors:Glenville Jones, Stephen A. Strugnell, and Hector F. DeLucaFrom:Physiological Reviews (Vol. 78, Issue 4) Peer-Reviewed

  Oct. 199831,725 words Article The metabolism of Vitamin D3 to the 1alpha,25-dihydroxyvitamin D3 (1,25-(OH)2D3) hormone involves 1alpha- and 24-hydroxylation reactions of the vitamin D hormone. This knowledge of vitamin D metabolism resulted in the...

• Gene expression and metabolite profiling of gibberellin biosynthesis during induction of somatic embryogenesis in Medicago truncatula Gaertn

  Authors:Rafal Igielski and Ewa KepczynskaFrom:PLoS ONE (Vol. 12, Issue 7) Peer-Reviewed

  July 27, 201716,230 words Report 1450LGibberellins (GAs) are involved in the regulation of numerous developmental processes in plants including zygotic embryogenesis, but their biosynthesis and role during somatic embryogenesis (SE) is mostly unknown. In...

• Toughening of Epoxy Thermosets with Polystyrene-block-Polybutadiene-block-Polystyrene Triblock Copolymer via Formation of Nanostructures.

  Authors:Hao Ding, Bingjie Zhao, Honggang Mei, Lei Li, and Sixun ZhengFrom:Polymer Engineering and Science (Vol. 59, Issue 11) Peer-Reviewed

  Nov. 20195,282 words Article 1340LIn this contribution, we reported to utilize polystyreneo/oc/ c-polybutadiene-o/oc/f-polystyrene(PS-b-PB-6-PS), a commercial triblock copolymer to toughen epoxy thermosets. First, a PS-o-PB-b-PS triblock copolymer was...

• Polysaccharide peptides from Coriolus versicolor competitively inhibit tolbutamide 4-hydroxylation in specific human CYP2C9 isoform and pooled human liver microsomes

  Authors:John H.K. Yeung and Penelope M.Y.From:Phytomedicine: International Journal of Phytotherapy & Phytopharmacology (Vol. 18, Issue 13) Peer-Reviewed

  Oct. 15, 20113,518 words Report 1510LARTICLE INFO Keywords: Polysaccharide peptide (PSP) Coriolus versicolor Tolbutamide metabolism 4-Hydroxytolbutamide Human CYP2C9 ABSTRACT Polysaccharide peptide (PSP), isolated from COV-1 strain of Coriolus...

• PLOD1 Is a Prognostic Biomarker and Mediator of Proliferation and Invasion in Osteosarcoma.

  Authors:Haoli Jiang, Wei Guo, Shanyou Yuan, and Lixia SongFrom:BioMed Research International (Vol. 2020) Peer-Reviewed

  Oct. 20, 20205,546 words Report 1330LObjective. Osteosarcoma is the most common primary bone tumor and most frequently develops during adolescence. PLOD family was mainly involved in lysyl hydroxylation and rarely investigated in cancers, especially in...

• Synthesis of Phenols via Metal-Free Hydroxylation of Aryl Boronic Acids with Aqueous TBHP.

  Author:Tanveer MahmadAlli ShaikhFrom:Journal of Chemistry (Vol. 2020) Peer-Reviewed

  July 31, 20204,849 words Article 1390LAn alternate procedure for oxidative hydroxylation of aryl boronic acids with aqueous TBHP to access phenols is described. The protocol tolerated various functional groups substituted with aromatic rings. The reaction...

• Structure of the Hydrated [Alpha]-[Al.sub.2][O.sub.3] (0001) Surface

  Authors:Peter J. Eng, Thomas P. Trainor, Gordon E. Jr. Brown, Glenn A. Waychunas, Matthew Newville, Stephen R. Sutton, et al.From:Science (Vol. 288, Issue 5468) Peer-Reviewed

  May 12, 20004,097 words Article The physical and chemical properties of the hydrated [Alpha]-[Al.sub.2][O.sub.3] (0001) surface are important for understanding the reactivity of natural and synthetic aluminum-containing oxides. The structure of this...

• Screening for novel hydroxylations by P450 biocatalysis. (News Briefs)

  From:Journal of Research of the National Institute of Standards and Technology (Vol. 107, Issue 2) Peer-Reviewed

  March-April 2002283 words Brief article Industries involved in manufacture of fine chemicals, pharmaceutical precursors such as the intermediates for Taxol or of high performance materials such as the polymers in bulletproof vests are searching for new...

• Low Vitamin-D Levels Combined with PKP3-SIGIRR-TMEM16J Host Variants Is Associated with Tuberculosis and Death in HIV-Infected and -Exposed Infants

  Authors:Amita Gupta, Grace Montepiedra, Akshay Gupte, Bret Zeldow, Jennifer Jubulis, Barbara Detrick, et al.From:PLoS ONE (Vol. 11, Issue 2) Peer-Reviewed

  Feb. 12, 20167,578 words Report 1600LBackground This study examined the associations of 25-hydroxyvitamin D and specific host genetic variants that affect vitamin D levels or its effects on immune function, with the risk of TB or mortality in children....

• Post-PKS Tailoring Steps of a Disaccharide-Containing Polyene NPP in Pseudonocardia autotrophica

  Authors:Hye-Jin Kim, Min-Kyung Kim, Mi-Jin Lee, Hyung-Jin Won, Si-Sun Choi, and Eung-Soo KimFrom:PLoS ONE (Vol. 10, Issue 4) Peer-Reviewed

  Apr. 7, 20155,203 words Article 1500LA novel polyene compound NPP identified in a rare actinomycetes, Pseudonocardia autotrophica KCTC9441, was shown to contain an aglycone identical to nystatin but to harbor a unique di-sugar moiety,...

• The Genome of the Moderate Halophile Amycolicicoccus subflavus DQS3-9A1.sup.T Reveals Four Alkane Hydroxylation Systems and Provides Some Clues on the Genetic Basis for Its Adaptation to a Petroleum Environment

  Authors:Yong Nie, Hui Fang, Yan Li, Chang-Qiao Chi, Yue-Qin Tang, and Xiao-Lei WuFrom:PLoS ONE (Vol. 8, Issue 8) Peer-Reviewed

  Aug. 14, 20137,529 words Article 1570LThe moderate halophile Amycolicicoccus subflavus DQS3-9A1.sup.T is the type strain of a novel species in the recently described novel genus Amycolicicoccus, which was isolated from oil mud precipitated from oil produced...