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    Academic Journals

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• Select hPepT1 selectively transports muramyl dipeptide but not Nod1-activating muramyl peptides

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  hPepT1 selectively transports muramyl dipeptide but not Nod1-activating muramyl peptides

  Authors:Manfred G. Ismair, Stephan R. Vavricka, Gerd A. Kullak-Ublick, Michael Fried, Dominique Mengin-Lecreulx, and Stephen E. GirardinFrom:Canadian Journal of Physiology and Pharmacology (Vol. 84, Issue 12) Peer-Reviewed

  Dec. 20064,427 words Article 1470LAbstract: Muramyl peptides derived from bacterial peptidoglycan are detected intracellularly by Nod1 and Nod2, 2 members of the newly characterized nod-like receptor (NLR) family of pattern recognition molecules. In the...
• Select Acute and delayed neuroinflammatory response following experimental penetrating ballistic brain injury in the rat

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  Acute and delayed neuroinflammatory response following experimental penetrating ballistic brain injury in the rat

  Authors:Anthony J. Williams, Hans H. Wei, Jitendra R. Dave, and Frank C. TortellaFrom:Journal of Neuroinflammation (Vol. 4) Peer-Reviewed

  July 2, 20075,598 words Article 1560LBackground Neuroinflammation following acute brain trauma is considered to play a prominent role in both the pathological and reconstructive response of the brain to injury. Here we characterize and contrast both an...
• Select TCF7L2 polymorphisms and inflammatory markers before and after treatment with fenofibrate

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  TCF7L2 polymorphisms and inflammatory markers before and after treatment with fenofibrate

  Authors:Edmond K. Kabagambe, Stephen P. Glasser, Jose M. Ordovas, Daruneewan Warodomwichit, Michael Y. Tsai, Paul N. Hopkins, et al.From:Diabetology & Metabolic Syndrome (Vol. 1) Peer-Reviewed

  Oct. 12, 20092,114 words Report Authors: Edmond K Kabagambe (corresponding author) [1]; Stephen P Glasser [2]; Jose M Ordovas [3]; Daruneewan Warodomwichit [4]; Michael Y Tsai [5]; Paul N Hopkins [6]; Ingrid B Borecki [7]; Mary Wojczynski [1,8]; Donna...
• Select Depression, osteoporosis and inflammatory dysfunction

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  Depression, osteoporosis and inflammatory dysfunction

  Author:Robert A. AndersonFrom:Townsend Letter for Doctors and Patients (Issue 261) Peer-Reviewed

  Apr. 2005323 words Brief article Depression is a major health problem with 13-20% of the population having depressive symptoms at any given time and [congruent to]5% experiencing major depression. Related pathological processes include ischemia,...
• Select The role of inflammation in insulitis and [beta]-cell loss in type 1 diabetes

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  The role of inflammation in insulitis and [beta]-cell loss in type 1 diabetes

  Authors:Decio L. Eizirik, Maikel L. Colli, and Fernanda OrtisFrom:Nature Reviews Endocrinology (Vol. 5, Issue 4) Peer-Reviewed

  Apr. 20096,742 words Report Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease with a strong inflammatory component. The latest studies indicate that innate immunity and inflammatory mediators have a much broader role in T1DM than...
• Select Inflammatory Mediators in Tracheal Aspirates of Preterm Infants Participating in a Randomized Trial of Inhaled Nitric Oxide

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  Inflammatory Mediators in Tracheal Aspirates of Preterm Infants Participating in a Randomized Trial of Inhaled Nitric Oxide

  Authors:Mandy Laube, Elena Amann, Ulrike Uhlig, Yang Yang, Hans W. Fuchs, Michael Zemlin, et al.From:PLoS ONE (Vol. 12, Issue 1) Peer-Reviewed

  Jan. 3, 20178,355 words Report 1470LBackground Ventilated preterm infants frequently develop bronchopulmonary dysplasia (BPD) which is associated with elevated inflammatory mediators in their tracheal aspirates (TA). In animal models of BPD, inhaled...
• Select Transcription factor network downstream of protease activated receptors (PARs) modulating mouse bladder inflammation

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  Transcription factor network downstream of protease activated receptors (PARs) modulating mouse bladder inflammation

  Authors:Ricardo Saban, Cindy Simpson, Carole A. Davis, Igor Dozmorov, Julie Maier, Ben Fowler, et al.From:BMC Immunology (Vol. 8) Peer-Reviewed

  Aug. 17, 200710,387 words Article 1440LBackground All four PARs are present in the urinary bladder, and their expression is altered during inflammation. In order to search for therapeutic targets other than the receptors themselves, we set forth to...
• Select Roles of interleukin-13 and interferon-[gamma] in lung inflammation *

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  Roles of interleukin-13 and interferon-[gamma] in lung inflammation *

  Authors:Gabriele Grunig, Jean G. Ford, Debra D. Donaldson, Rajeev Venkayya, Cliff McArthur, Elisabeth Hansell, et al.From:Chest (Vol. 121, Issue 3) Peer-Reviewed

  Mar. 2002403 words Article Abbreviations: IFN = interferon; IL = interleukin; Th = T helper In human patients, asthma frequently is associated with mixed T helper (Th) cell responses. Th2 and Th1 cytokines (eg, interleukin [IL]-13 and...
• Select Inhibition of HMGB1 protects the retina from ischemia-reperfusion, as well as reduces insulin resistance proteins

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  Inhibition of HMGB1 protects the retina from ischemia-reperfusion, as well as reduces insulin resistance proteins

  Authors:Li Liu, Youde Jiang, and Jena J. SteinleFrom:PLoS ONE (Vol. 12, Issue 5) Peer-Reviewed

  May 23, 20174,214 words Report 1370LThe role of inflammation in diabetic retinal amage is well accepted. While a number of cytokines and inflammatory mediators are responsible for these changes, upstream regulators are less well studied. Additionally, the...
• Select A Murine Model of Volutrauma(*)

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  A Murine Model of Volutrauma(*)

  Authors:T. Jr. Gronski, E. Lum, J. Campbell, and S. D. ShapiroFrom:Chest (Vol. 116, Issue 1) Peer-Reviewed

  July 1999445 words Article Potential Contribution of Inflammatory Cell Proteases to Lung Injury (CHEST 1999; 116:28S) Although mechanical ventilation is recognized as an invaluable method of support for patients with severe respiratory...
• Select Inflammatory responses in the lung and cell activity indicators

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  Inflammatory responses in the lung and cell activity indicators

  Authors:Lena Beijer, Robert R. Jacobs, and Ragnar RylanderFrom:Chest (Vol. 109, Issue 3) Peer-Reviewed

  Mar. 1996315 words Brief article There is increasing evidence that symptoms and disease caused by inhalation of organic dust are related to airways inflammation. To evaluate if cellular parameters are related to airways inflammation, subjects were...
• Select FSTL1 aggravates cigarette smoke-induced airway inflammation and airway remodeling by regulating autophagy.

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  FSTL1 aggravates cigarette smoke-induced airway inflammation and airway remodeling by regulating autophagy.

  Authors:Ying Liu, Jiawei Xu, Tian Liu, Jinxiang Wu, Jiping Zhao, Junfei Wang, et al.From:BMC Pulmonary Medicine (Vol. 21, Issue 1) Peer-Reviewed

  Jan. 28, 20215,650 words Report 1400LBackground Cigarette smoke (CS) is a major risk factor for Chronic Obstructive Pulmonary Disease (COPD). Follistatin-like protein 1 (FSTL1), a critical factor during embryogenesis particularly in respiratory lung...
• Select Cell stress molecules in the skeletal muscle of GNE myopathy

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  Cell stress molecules in the skeletal muscle of GNE myopathy

  Authors:Charlotte Fischer, Konstanze Kleinschnitz, Arne Wrede, Ingrid Muth, Niels Kruse, Ichizo Nishino, et al.From:BMC Neurology (Vol. 13, Issue 1) Peer-Reviewed

  Mar. 12, 20134,280 words Report 1470LAuthor(s): Charlotte Fischer1 , Konstanze Kleinschnitz1,2 , Arne Wrede3 , Ingrid Muth1 , Niels Kruse2,3 , Ichizo Nishino4 and Jens Schmidt1,2 Background GNE myopathy has previously been also termed quadriceps...
• Select Variation of inflammatory dynamics and mediators in primiparous cows after intramammary challenge with Escherichia coli

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  Variation of inflammatory dynamics and mediators in primiparous cows after intramammary challenge with Escherichia coli

  Authors:Adel Pezeshki, Philippe Stordeur, Hugues Wallemacq, Frederic Schynts, Mieke Stevens, Philippe Boutet, et al.From:Veterinary Research (Vol. 42) Peer-Reviewed

  Jan. 24, 20116,368 words Report 1380LThe objective of the current study was to investigate (i) the outcome of experimentally induced Escherichia coli mastitis in primiparous cows during early lactation in relation with production of eicosanoids and...
• Select Sputum mediator profiling and relationship to airway wall geometry imaging in severe asthma

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  Sputum mediator profiling and relationship to airway wall geometry imaging in severe asthma

  Authors:Dhananjay Desai, Sumit Gupta, Salman Siddiqui, Amisha Singapuri, William Monteiro, James Entwisle, et al.From:Respiratory Research (Vol. 14, Issue 1) Peer-Reviewed

  Feb. 11, 20135,516 words Clinical report 1630LBackground Severe asthma is a heterogeneous disease and the relationship between airway inflammation and airway remodelling is poorly understood. We sought to define sputum mediator profiles in severe asthmatics...
• Select Evolving concepts on the value of adenosine hyperresponsiveness in asthma and chronic obstructive pulmonary disease. (Occasional Review)

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  Evolving concepts on the value of adenosine hyperresponsiveness in asthma and chronic obstructive pulmonary disease. (Occasional Review)

  Authors:R. Polosa, S. Rorke, and S.T. HolgateFrom:Thorax (Vol. 57, Issue 7) Peer-Reviewed

  July 20026,235 words Article Adenosine is a purine nucleoside which mediates a variety of cellular responses relevant to asthma and COPD through interaction with specific receptors. Administration of adenosine by inhalation to patients with asthma...
• Select Increased activity of interleukin-23/interleukin-17 proinflammatory axis in obese women

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  Increased activity of interleukin-23/interleukin-17 proinflammatory axis in obese women

  Authors:M. Sumarac-Dumanovic, D. Stevanovic, A. Ljubic, J. Jorga, M. Simic, D. Stamenkovic-Pejkovic, et al.From:International Journal of Obesity (Vol. 33, Issue 1) Peer-Reviewed

  Jan. 20093,936 words Report To compare the concentrations of cytokines belonging to Th17 axis (interleukin (IL)-17 and IL-23) and Th1 axis (IL-12 and interferon (IFN)-[gamma]) in obese and lean women, and to investigate their relationships with...
• Select Effects of ambient air pollution on hemostasis and inflammation

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  Effects of ambient air pollution on hemostasis and inflammation

  Authors:Flemming R. Cassee, Hugo ten Cate, Moniek P.M. de Maat, Miriam E. Gerlofs-Nijland, Nicole A.H. Janssen, Evren Kilinc, et al.From:Environmental Health Perspectives (Vol. 117, Issue 6) Peer-Reviewed

  June 20095,128 words Report 1460LBACKGROUND: Air pollution has consistently been associated with increased morbidity and mortality due to respiratory and cardiovascular disease. Underlying biological mechanisms are not entirely clear, and hemostasis...
• Select New insights on fibrosis in Crohn's disease

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  New insights on fibrosis in Crohn's disease

  Authors:Jennifer R. Bailey, Christine V. Whiting, John F. Tarlton, Paul W. Bland, and Christopher S.J. ProbertFrom:Expert Review of Gastroenterology & Hepatology (Vol. 7, Issue 6) Peer-Reviewed

  Aug. 20132,306 words Report 1480LAuthor(s): Jennifer R Bailey [*] 1 , Christine V Whiting 2 , John F Tarlton 3 , Paul W Bland 4 , Christopher SJ Probert 5 Keywords : collagen; Crohn's disease; extracellular matrix; fibrosis; inflammation...
• Select Data on Inflammation Detailed by Researchers at Louvain Drug Research Institute

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  Data on Inflammation Detailed by Researchers at Louvain Drug Research Institute

  From:Obesity, Fitness & Wellness Week

  Feb. 1, 2014424 words Article 1420LBy a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on Inflammation have been published. According to news originating from Brussels, Belgium, by NewsRx correspondents,...