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• Management of inflammatory bowel disease in pregnancy

  Authors:Susie W. Ng and Uma MahadevanFrom:Expert Review of Clinical Immunology (Vol. 9, Issue 2) Peer-Reviewed

  Feb. 201310,926 words Report 1490LAuthor(s): Susie W Ng 1 , Uma Mahadevan [*] 2 Keywords : biologics; corticosteroids; Crohn's disease; disease flare; heritability; inflammatory bowel disease; infliximab; pregnancy; thiopurines; ulcerative...

• Inflammatory bowel disease activity assessed by fecal calprotectin and lactoferrin: correlation with laboratory parameters, clinical, endoscopic and histological indexes

  Authors:Andrea Vieira, Chia Bin Fang, Ernani Geraldo Rolim, Wilmar Artur Klug, Flavio Steinwurz, Lucio Giovanni Battista Rossini, et al.From:BMC Research Notes (Vol. 2) Peer-Reviewed

  Oct. 29, 20093,328 words Clinical report Authors: Andrea Vieira (corresponding author) [1]; Chia Bin Fang [2]; Ernani Geraldo Rolim [1]; Wilmar Artur Klug [2]; Flávio Steinwurz [3]; Lucio Giovanni Battista Rossini [4]; Paulo Azevedo Candelária [2] Findings...

• Thiopurine methyl transferase activity predicts both toxicity and clinical response to azathioprine in inflammatory bowel disease: the London IBD forum prospective study

  Authors:A. Ansari, M. Arenas, J. Lindsay, D. Morris, S. Greenfield, T. Khanbai, et al.From:Gut (Vol. 53, Issue 4) Peer-Reviewed

  Apr. 2004281 words Brief article Background: Thiopurine methyl transferase (TPMT) deficiency increases the catabolism of azathioprine (AZA) to cytotoxic thioguanine nucleotides, leading to increased toxicity. Theoretically, higher TPMT activity should...

• researcH

  From:Practice Nurse

  Jan. 16, 2004116 words Brief article Children with inflammatory bowel disease Arch Dis Child 2003; 88: 995-1000. Many children with inflammatory bowel disease (IBD) in the UK and Ireland are diagnosed only after prolonged delays, say researchers. A team...

• The genetic jigsaw of inflammatory bowel disease. (Paper)

  Authors:D.A. Watts and J. SatsangiFrom:Gut (Vol. 50, Issue 5) Peer-Reviewed

  May 20026,302 words Article Following a prolonged period of relative inertia, real progress has been made in the past few years in understanding the pathogenesis of the chronic inflammatory bowel diseases, Crohn's disease and ulcerative colitis....

• Neglect of growth and development in the clinical monitoring of children and teenagers with inflammatory bowel disease: review of case records

  Authors:Subrata Ghosh, Hazel E. Drummond, and Anne FergusonFrom:British Medical Journal (Vol. 317, Issue 7151) Peer-Reviewed

  July 11, 19981,325 words Article Failure of growth and retarded sexual development are serious and common problems in children and teenagers with inflammatory bowel disease, particularly Crohn's disease. Thus height, weight, sexual staging, and bone age...

• Ulcerative colitis and Crohn's disease: important and disabling diseases, still underresearched

  Author:Anne FergusonFrom:British Medical Journal (Vol. 309, Issue 6951) Peer-Reviewed

  Aug. 6, 19941,129 words Editorial In the past four years three excellent and comprehensive books on inflammatory bowel disease have been published.(1)(2)(3) In a total of 1812 pages 156 contributors provide detailed accounts of the recent striking rise...

• Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin

  Authors:Michelle L. Hermiston and Jeffrey I. GordonFrom:Science (Vol. 270, Issue 5239) Peer-Reviewed

  Nov. 17, 19952,364 words Article Cadherins mediate cell adhesion and are essential for normal development. Embryonic stem cells were tranfected with a dominant negative N-cadherin mutant (NCAD[delta]) under the control of promoters active in small...

• Vitamin D and inflammatory bowel disease

  Authors:Marco Ardesia, Guido Ferlazzo, and Walter FriesFrom:BioMed Research InternationalPeer-Reviewed

  Annual 20159,355 words Report 1600LVitamin D deficiency has been recognized as an environmental risk factor for Crohn's disease since the early 80s. Initially, this finding was correlated with metabolic bone disease. Low serum 25-hydroxyvitamin D levels...

• Immunocompetent host develops mild intestinal inflammation in acute infection with Toxoplasma gondii

  Authors:Paulo da Silva Watanabe, Aline Rosa Trevizan, Saulo Euclides Silva-Filho, Marcelo Biondaro Gois, Joao Luiz Garcia, Roberto Kenji Nakamura Cuman, et al.From:PLoS ONE (Vol. 13, Issue 1) Peer-Reviewed

  Jan. 11, 20186,038 words Report 1340LAuthor(s): Paulo da Silva Watanabe 1, Aline Rosa Trevizan 1, Saulo Euclides Silva-Filho 2, Marcelo Biondaro Góis 1, João Luiz Garcia 3, Roberto Kenji Nakamura Cuman 2, Ana Cristina Breithaupt-Faloppa 4, Débora de Mello...

• Classical and recent advances in the treatment of inflammatory bowel diseases

  Authors:H. Sales-Campos, P.J. Basso, V.B.F. Alves, M.T.C. Fonseca, G. Bonfa, V. Nardini, et al.From:Brazilian Journal of Medical and Biological Research (Vol. 48, Issue 2) Peer-Reviewed

  Feb. 20159,232 words Report 1530LCrohn's disease (CD) and ulcerative colitis (UC) are intestinal disorders that comprise the inflammatory bowel diseases (IBD). These disorders have a significant effect on the quality of life of affected patients and...

• The efficacy of azathioprine for the treatment of inflammatory bowel disease: A 30 year review. (Original Article)

  Authors:T.R. Orchard, D.P. Jewell, and A.G. FraserFrom:Gut (Vol. 50, Issue 4) Peer-Reviewed

  Apr. 20024,006 words Article Background: There are limited data on factors predicting response to azathioprine and uncertainty regarding the optimal duration of treatment. Patients and methods: The notes of patients attending the Oxford IBD...

• Ulcerative colitis, Crohn's disease, and irritable bowel syndrome have different profiles of extracellular matrix turnover, which also reflects disease activity in Crohn's disease

  Authors:Joachim Hog Mortensen, Tina Manon-Jensen, Michael Dam Jensen, Per Hagglund, Lone Gabriels Klinge, Jens Kjeldsen, et al.From:PLoS ONE (Vol. 12, Issue 10) Peer-Reviewed

  Oct. 13, 20176,542 words Report 1440LBackground Increased protease activity is a key pathological feature of inflammatory bowel disease (IBD). However, the differences in extracellular matrix remodelling (ECM) in Crohn's disease (CD) and ulcerative...

• Risk factors for gallstones and kidney stones in a cohort of patients with inflammatory bowel diseases

  Authors:Stefania Fagagnini, Henriette Heinrich, Jean-Benoit Rossel, Luc Biedermann, Pascal Frei, Jonas Zeitz, et al.From:PLoS ONE (Vol. 12, Issue 10) Peer-Reviewed

  Oct. 12, 20175,103 words Report 1410LBackground Gallstones and kidney stones are known complications of inflammatory bowel diseases (IBD). Risk factors have been insufficiently studied and explanatory studies date back up to 30 years. It remains...

• Occurrence of skin manifestations in patients of the Swiss Inflammatory Bowel Disease Cohort Study

  Authors:Nina Roth, Luc Biedermann, Nicolas Fournier, Matthias Butter, Stephan R. Vavricka, Alexander A. Navarini, et al.From:PLoS ONE (Vol. 14, Issue 1) Peer-Reviewed

  Jan. 25, 20195,971 words Report 1430LBackground/Aims Extraintestinal cutaneous manifestations of IBD represent a severe disease complication and an early and accurate treatment might positively influence the disease course. Using the patient collective...

• Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

  Authors:Jason Lloyd-Price, Cesar Arze, Ashwin N. Ananthakrishnan, Melanie Schirmer, Julian Avila-Pacheco, Tiffany W. Poon, et al.From:Nature (Vol. 569, Issue 7758) Peer-Reviewed

  May 201919,831 words Clinical report 1510LInflammatory bowel diseases, which include Crohn's disease and ulcerative colitis, affect several million individuals worldwide. Crohn's disease and ulcerative colitis are complex diseases that are heterogeneous at the...

• Potential role of NK cells in the pathogenesis of inflammatory bowel disease

  Authors:Praveen K. Yadav, Chi Chen, and Zhanju LiuFrom:Journal of Biomedicine and BiotechnologyPeer-Reviewed

  Annual 20115,267 words Report 1560LNK cells are a major component of the innate immune system and play an important role in the tissue inflammation associated with autoimmune diseases such as inflammatory bowel disease (IBD). NK cells are unique in...

• Two-way link found between IBD, cervical cancer

  Author:Amy KaronFrom:Family Practice News (Vol. 45, Issue 5)

  Mar. 15, 2015491 words Article 1540LFROM CLINICAL GASTROENTEROLOGY AND HEPATOLOGY Women with Crohn's disease had about a 53% greater risk of developing cervical cancer compared with controls, and women with inflammatory bowel disease had a...

• Thiopurine therapy in inflammatory bowel disease

  Authors:Christina Ha and Themistocles DassopoulosFrom:Expert Review of Gastroenterology & Hepatology (Vol. 4, Issue 5) Peer-Reviewed

  Oct. 201011,578 words Report 1290LAuthor(s): Christina Ha 1 , Themistocles Dassopoulos [[dagger]] 2 Keywords : 6-mercaptopurine; 6-thioguanine; azathioprine; Crohn'âs disease; infliximab; thiopurine methyltransferase; ulcerative colitis The...

• Inflammatory bowel disease in the elderly

  Authors:Syed Wasif Hussain and Darrell S. PardiFrom:Drugs & Aging (Vol. 27, Issue 8) Peer-Reviewed

  Aug. 20104,845 words Disease/Disorder ove... Although inflammatory bowel disease (IBD) is generally considered a disease of young adults, it can occur in elderly individuals. The clinical features and treatment considerations in older patients are similar to those...