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    Academic Journals

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• IP-10, MCP-1, MCP-2, MCP-3, and IL-1RA hold promise as biomarkers for infection with M. tuberculosis in a whole blood based T-cell assay

  Authors:Morten Ruhwald, Morten Bjerregaard-Andersen, Paulo Rabna, Jesper Eugen-Olsen, and Pernille RavnFrom:BMC Research Notes (Vol. 2) Peer-Reviewed

  Feb. 4, 20092,785 words Report Authors: Morten Ruhwald (corresponding author) [1,2]; Morten Bjerregaard-Andersen [3,4]; Paulo Rabna [4]; Jesper Eugen-Olsen [2]; Pernille Ravn [2,5] Background Until recently the tuberculin skin test has been the...

• Interferon Gamma-Dependent Intestinal Pathology Contributes to the Lethality in Bacterial Superantigen-Induced Toxic Shock Syndrome

  Authors:Ashenafi Y. Tilahun, Marah Holz, Tsung-Teh Wu, Chella S. David, and Govindarajan RajagopalanFrom:PLoS ONE (Vol. 6, Issue 2) Peer-Reviewed

  Feb. 3, 20117,114 words Article 1410LToxic shock syndrome (TSS) caused by the superantigen exotoxins of Staphylococcus aureus and Streptococcus pyogenes is characterized by robust T cell activation, profound elevation in systemic levels of multiple...

• Tuberculin skin test and QuantiFERON-Gold In Tube assay for diagnosis of latent TB infection among household contacts of pulmonary TB patients in high TB burden setting

  Authors:Padmapriyadarsini Chandrasekaran, Vidya Mave, Kannan Thiruvengadam, Nikhil Gupte, Shri Vijay Bala Yogendra Shivakumar, Luke Elizabeth Hanna, et al.From:PLoS ONE (Vol. 13, Issue 8) Peer-Reviewed

  Aug. 1, 20185,986 words Report 1440LBackground World Health Organization (WHO) recommends systematic screening of high-risk populations, including household contacts (HHCs) of adult pulmonary tuberculosis (TB) patients, as a key strategy for...

• Toxoplasmic retinochoroiditis: The influence of age, number of retinochoroidal lesions and genetic polymorphism for IFN-[gamma] +874 T/A as risk factors for recurrence in a survival analysis

  Authors:Ana Luisa Quintella do Couto Aleixo, Raquel Vasconcelos C. de Oliveira, Maira Cavalcanti Albuquerque, Ana Luiza Biancardi, Andre Luiz Land Curi, Eliezer Israel Benchimol, et al.From:PLoS ONE (Vol. 14, Issue 2) Peer-Reviewed

  Feb. 12, 20193,559 words Report 1750LPurpose To analyze risk factors for recurrent toxoplasmic retinochoroiditis. Design Single center prospective case series. Population and Methods A total of 230 patients with toxoplasmic retinochoroiditis...

• Vaccination procedures against coxsackievirus-induced heart disease

  Authors:Andreas Henke, Nadine Jarasch, and Peter WutzlerFrom:Expert Review of Vaccines (Vol. 2, Issue 6) Peer-Reviewed

  Dec. 1, 20038,323 words Report Coxsackievirus B3 - a member of the picornavirus family - is one of the major causes of virus-induced acute or chronic heart disease. Despite the fact that the molecular structure of this pathogen has been characterized...

• Diagnostic performance of interferon-Gamma assay for tuberculosis in immunocompromised patients

  Authors:Shih-Yang Su, Chien-Ming Chao, and Chih-Cheng LaiFrom:Annals of Thoracic Medicine (Vol. 8, Issue 1) Peer-Reviewed

  January-March 2013333 words Brief article, Lette... 2050LByline: Shih-Yang. Su, Chien-Ming. Chao, Chih-Cheng. Lai Sir, We read with great interest a recent article by Eldin et al . who investigated the utility of interferon (INF)-a level and Quantiferon-TB Gold In tube...

• A stress-responsive RNA switch regulates VEGFA expression

  Authors:Partho Sarothi Ray, Jie Jia, Peng Yao, Mithu Majumder, Maria Hatzoglou, and Paul L. FoxFrom:Nature (Vol. 457, Issue 7231) Peer-Reviewed

  Feb. 12, 20093,739 words Report Ligand binding to structural elements in the non-coding regions of messenger RNA modulates gene expression (1,2). Ligands such as free metabolites or other small molecules directly bind and induce conformational changes...

• Identification of an IFN-[gamma]/mast cell axis in a mouse model of chronic asthma

  Authors:Mang Yu, Michael R. Eckart, Alexander A. Morgan, Kaori Mukai, Atul J. Butte, Mindy Tsai, et al.From:Journal of Clinical Investigation (Vol. 121, Issue 8) Peer-Reviewed

  Aug. 20118,041 words Report 1710LAsthma is considered a Th2 cell-associated disorder. Despite this, both the Th1 cell-associated cytokine IFN-[gamma] and airway neutrophilia have been implicated in severe asthma. To investigate the relative...

• In Vivo Interrelationship between Insulin Resistance and Interferon Gamma Production: Protective and Therapeutic Effect of Berberine.

  Authors:Mohammad Ahmad Mahmoud, Doaa Ahmad Ghareeb, Heba Abdelghany Sahyoun, Ashraf Abdelhamed Elshehawy, and Mohammad Mohammad ElsayedFrom:Evidence - Based Complementary and Alternative MedicinePeer-Reviewed

  Annual 20164,948 words Article 1570LThis research was conducted to investigate if there is a relation between insulin resistance incidence and inhibition of interferon gamma production or not. Firstly, insulin resistance was induced by high fat diet (HFD)...

• Failure of Interferon [gamma] to Induce the Anti-Inflammatory Interleukin 18 Binding Protein in Familial Hemophagocytosis

  Authors:Claudia A. Nold-Petry, Thomas Lehrnbecher, Andrea Jarisch, Dirk Schwabe, Josef M. Pfeilschifter, Heiko Muhl, et al.From:PLoS ONE (Vol. 5, Issue 1) Peer-Reviewed

  Jan. 13, 20104,631 words Article 1390LBackground Familial hemophagocytosis (FHL) is a rare disease associated with defects in proteins involved in CD8.sup.+ T-cell cytotoxicity. Hyperactivation of immune cells results in a perilous, Th1-driven cytokine...

• Potential of Host Markers Produced by Infection Phase-Dependent Antigen-Stimulated Cells for the Diagnosis of Tuberculosis in a Highly Endemic Area

  Authors:Novel N. Chegou, Paulin N. Essone, Andre G. Loxton, Kim Stanley, Gillian F. Black, Gian D. van der Spuy, et al.From:PLoS ONE (Vol. 7, Issue 6) Peer-Reviewed

  June 5, 20126,678 words Article 1620LAuthor(s): Novel N. Chegou 1 , * , Paulin N. Essone 1 , Andre G. Loxton 1 , Kim Stanley 1 , Gillian F. Black 1 , Gian D. van der Spuy 1 , Paul D. van Helden 1 , Kees L. Franken 2 , Shreemanta K. Parida 3 , Michel R....

• Group B Streptococcus Induces a Robust IFN-[gamma] Response by [CD4.sup.+] T Cells in an In Vitro and In Vivo Model

  Authors:Damian Clarke, Corinne Letendre, Marie-Pier Lecours, Paul Lemire, Tristan Galbas, Jacques Thibodeau, et al.From:Journal of Immunology Research (Vol. 2016) Peer-Reviewed

  Annual 20167,022 words Report 1300LGroup B Streptococcus (GBS) serotype III causes life-threatening infections. Cytokines have emerged as important players for the control of disease, particularly IFN-[gamma]. Although potential sources of this cytokine...

• Alkaloid immunomodulatory effects of sambiloto (andrographis paniculate l.) on the response of gamma interferon and t helper cell ([cd4.sup.+])

  Authors:Wurlina, Dewa Ketut Meles, Imam Mustofa, Sunarni Zakaria, and I. Dewa Putu Anom AdnyanaFrom:Advances in Natural and Applied Sciences (Vol. 11, Issue 9) Peer-Reviewed

  July 1, 20172,394 words Report 1790LThis research aims to demonstrate the immunomodulatory effects of alkaloid sambiloto on innate immunity and adaptive immunity in helping the body maintain and regulate the immune system due to low body resistance during...

• Interferon-[Gamma] Receptor Signaling Is Dispensable in the Development of Autoimmune Type 1 Diabetes in NOD Mice

  Authors:David V. Serreze, Cristina M. Post, Harold D. Chapman, Ellis A. Johnson, Binfeng Lu, and Paul B. RothmanFrom:Diabetes (Vol. 49, Issue 12) Peer-Reviewed

  Dec. 20003,563 words Article There have been two previous conflicting reports that the development of T-cell-mediated autoimmune diabetes (type 1 diabetes) was respectively unaffected or inhibited in NOD mice genetically deficient in the T-helper...

• Quiescent haematopoietic stem cells are activated by IFN-[gamma] in response to chronic infection

  Authors:Megan T. Baldridge, Katherine Y. King, Nathan C. Boles, David C. Weksberg, and Margaret A. GoodellFrom:Nature (Vol. 465, Issue 7299) Peer-Reviewed

  June 10, 20105,112 words Report 1520LLymphocytes and neutrophils are rapidly depleted by systemic infection (1). Progenitor cells of the haematopoietic system, such as common myeloid progenitors and common lymphoid progenitors, increase the production of...

• Cost effectiveness of interferon-gamma release assay versus chest x-ray for tuberculosis screening of BCG-vaccinated elderly populations

  Authors:Akiko Kowada, Gautam A. Deshpande, Osamu Takahashi, Takuro Shimbo, and Tsuguya FukuiFrom:Molecular Diagnosis & Therapy (Vol. 14, Issue 4) Peer-Reviewed

  July-August 20103,753 words Clinical report Background: The prevalence of tuberculosis (TB) in the elderly is higher than that in the general population, and elderly populations are considered a high-risk group. Currently, annual TB screening of Bacille...

• Investigation of Toll-Like Receptor-2 (2258G/A) and Interferon Gamma (+874T/A) Gene Polymorphisms among Infertile Women with Female Genital Tuberculosis

  Authors:Venkanna Bhanothu, Vemu Lakshmi, Jane P. Theophilus, Roya Rozati, Prabhakar Badhini, and Boda VijayalaxmiFrom:PLoS ONE (Vol. 10, Issue 6) Peer-Reviewed

  June 26, 201513,873 words Article 1630LBackground Toll-like receptor 2 (TLR2) and interferon-gamma (IFN-[gamma]) coordinate with a diverse array of cellular programs through the transcriptional regulation of immunologically relevant genes and play an...

• Adult Human Glia, Pericytes and Meningeal Fibroblasts Respond Similarly to IFNy but Not to TGF[beta].sub.1 or M-CSF

  Authors:Amy M. Smith, E. Scott Graham, Sheryl Xia Feng, Robyn L. Oldfield, Peter M. Bergin, Edward W. Mee, et al.From:PLoS ONE (Vol. 8, Issue 12) Peer-Reviewed

  Dec. 5, 201310,386 words Article 1420LThe chemokine Interferon gamma-induced protein 10 (IP-10) and human leukocyte antigen (HLA) are widely used indicators of glial activation and neuroinflammation and are up-regulated in many brain disorders. These...

• QuantiFERON-TB Gold In-tube test for the diagnosis of active and latent tuberculosis in selected health facilities of Addis Ababa, Ethiopia

  Authors:Selam Niguse, Kassu Desta, Gebremdihin Gebremichael, Atsebeha Gebrezgeaxier, Mulluwork Getahun, and Desta KassaFrom:BMC Research Notes (Vol. 11, Issue 1) Peer-Reviewed

  May 11, 20183,166 words Report 1370LObjective To determine the performance of QuantiFERON-TB IN-Gold for the diagnosis active tuberculosis and latent tuberculosis. Results A total of 213 participants (136 tuberculosis suspects, 66 latently...

• Immune vulnerability of infants to tuberculosis

  Authors:Koen Vanden Driessche, Alexander Persson, Ben J. Marais, Pamela J. Fink, and Kevin B. UrdahlFrom:Journal of Immunology Research (Vol. 2013) Peer-Reviewed

  Annual 201314,631 words Report 1500LOne of the challenges faced by the infant immune system is learning to distinguish the myriad of foreign but nonthreatening antigens encountered from those expressed by true pathogens. This balance is reflected in the...