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    Academic Journals

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• K.S. Kobayashi et al., "Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

  Author:Xiaojing MaFrom:The Scientist (Vol. 19, Issue 8) Peer-Reviewed

  Apr. 25, 200594 words Brief article K.S. Kobayashi et al., "Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract," Science, 307:731-4, Feb. 4, 2005. This study provides strong confirmation evidence supporting one of the...

• The locally acting glucocorticosteroid budesonide enhances intestinal sugar uptake following intestinal resection in rats. (Inflammation and Inflammatory Bowel Disease)

  Authors:A. Thiesen, G.E. Wild, K.A. Tappenden, L. Drozdowski, M. Keelan, B.K.A. Thomson, et al.From:Gut (Vol. 52, Issue 2) Peer-Reviewed

  Feb. 20036,297 words Article Background and aims: Locally and systemically acting corticosteroids alter the morphology and transport function of the intestine. This study was undertaken to assess the effect of budesonide, prednisone, and...

• Acute and chronic intestinal motor activity responses to two infant formulas

  Authors:Sudarshan R. Jadcherla and Carol Lynn BersethFrom:Pediatrics (Vol. 96, Issue 2) Peer-Reviewed

  Aug. 19953,849 words Article Objective. Preterm formulas are nutritionally better for preterm infants; however, it has been observed that these formulas cause more feeding intolerance than do regular formulas. Because intestinal motor activity is...

• Regeneration: Stem cells make the bowel nervous

  Author:Robert O. HeuckerothFrom:Nature (Vol. 531, Issue 7592) Peer-Reviewed

  Mar. 3, 20161,404 words Article 1530LAuthor(s): Robert O. Heuckeroth (corresponding author) [1] The enteric nervous system (ENS) is a network of neurons and supporting glial cells in the bowel wall that is essential for digestion [1]. When ENS precursor...

• Quantitative microbiome profiling links gut community variation to microbial load

  Authors:Doris Vandeputte, Gunter Kathagen, Kevin Dhoe, Sara Vieira-Silva, Mireia Valles-Colomer, Joo Sabino, et al.From:Nature (Vol. 551, Issue 7681) Peer-Reviewed

  Nov. 23, 20177,708 words Report 1390LAuthor(s): Doris Vandeputte [1, 2, 3]; Gunter Kathagen [1, 2]; Kevin Dhoe [1, 2, 3]; Sara Vieira-Silva [1, 2]; Mireia Valles-Colomer [1, 2]; Joo Sabino [4]; Jun Wang [1, 2]; Raul Y. Tito [1, 2, 3]; Lindsey De Commer...

• Signal integration by [Ca.sup.2+] regulates intestinal stem-cell activity

  Authors:Hansong Deng, Akos A. Gerencser, and Heinrich JasperFrom:Nature (Vol. 528, Issue 7581) Peer-Reviewed

  Dec. 10, 20156,605 words Report 1530LSomatic stem cells maintain tissue homeostasis by dynamically adjusting proliferation and differentiation in response to stress and metabolic cues. Here we identify [Ca.sup.2+] signalling as a central regulator of...

• 39-Year-Old Woman With Constipation and Abdominal Pain

  Authors:S. Bradley Hicks, Amrit K. Kamboj, and Conor G. LoftusFrom:Mayo Clinic Proceedings (Vol. 93, Issue 9) Peer-Reviewed

  Sept. 20182,771 words Report 1430LA 39-year-old woman presented to the clinic with an 8-month history of worsening constipation, abdominal pain, and intermittent episodes of hematochezia. On average, she reported having one bowel movement per week. Each...

• The putative role of inflammation in the irritable bowel syndrome. (Leading Article)

  Authors:S.M. Collins, T. Piche, and P. RampalFrom:Gut (Vol. 49, Issue 6) Peer-Reviewed

  Dec. 20012,449 words Article The irritable bowel syndrome (IBS) may be defined as a painful chronic abdominal symptom complex which is usually associated with altered bowel habit, and for which there is no discernible underlying structural...

• Identification of NF-[kappa]B modulation capabilities within human intestinal commensal bacteria

  Authors:Omar Lakhdari, Julien Tap, Fabienne Beguet-Crespel, Karine Le Roux, Tomas de Wouters, Antonietta Cultrone, et al.From:Journal of Biomedicine and BiotechnologyPeer-Reviewed

  Annual 20114,218 words Report 1430LThe intestinal microbiota plays an important role in modulation of mucosal immune responses. To seek interactions between intestinal epithelial cells (IEC) and commensal bacteria, we screened 49 commensal strains for...

• Development of bioadhesive chitosan superporous hydrogel composite particles based intestinal drug delivery system

  Authors:Hitesh Chavda, Ishan Modhia, Anant Mehta, Rupal Patel, and Chhagan PatelFrom:BioMed Research InternationalPeer-Reviewed

  Annual 20134,553 words Report 1350LBioadhesive superporous hydrogel composite (SPHC) particles were developed for an intestinal delivery of metoprolol succinate and characterized for density, porosity, swelling, morphology, and bioadhesion studies....

• Self-organization and symmetry breaking in intestinal organoid development

  Authors:Denise Serra, Urs Mayr, Andrea Boni, Ilya Lukonin, Markus Rempfler, Ludivine Challet Meylan, et al.From:Nature (Vol. 569, Issue 7754) Peer-Reviewed

  May 20195,923 words Report 1510LIntestinal organoids are complex three-dimensional structures that mimic the cell-type composition and tissue organization of the intestine by recapitulating the self-organizing ability of cell populations derived from...

• A new set of reference housekeeping genes for the normalization RT-qPCR data from the intestine of piglets during weaning

  Authors:Shujin Wang, Binxing Wang, Huan He, Aomin Sun, and Chunhua GuoFrom:PLoS ONE (Vol. 13, Issue 9) Peer-Reviewed

  Sept. 26, 20186,694 words Report 1590LThe intestinal mucosal development of piglets (Sus scrofa) during the weaning stage is important to their disease susceptibility and later growth. Quantitative real-time PCR (RT-qPCR) is commonly used to screen for...

• Nutritional complications and management of intestinal transplant

  Authors:HEIDI J. SILVER and VICTORIA H. CASTELLANOSFrom:Journal of the American Dietetic Association (Vol. 100, Issue 6) Peer-Reviewed

  June 20006,380 words Article ABSTRACT Advances in intestinal transplantation provide a promising alternative to patients with intestinal failure and chronic dependence on total parenteral nutrition. However, many physiologic complications...

• A pulsating gut on a chip

  From:Nature (Vol. 483, Issue 7390) Peer-Reviewed

  Mar. 22, 2012176 words Brief article 1330LA coin-sized device created by a team at Harvard University mimics the structure and physiology of the human intestine by supporting gut microbes and imitating the organ's rhythmic motion. Donald Ingber and his...

• Regulation of Intestinal [Alpha]-Defensin Activation by the Metalloproteinase Matrilysin in Innate Host Defense

  Authors:Carole L. Wilson, Andre J. Ouellette, Donald P. Satchell, Tokiyoshi Ayabe, Yolanda S. Lopez-Boado, Jennifer L. Stratman, et al.From:Science (Vol. 286, Issue 5437) Peer-Reviewed

  Oct. 1, 19993,517 words Article Precursors of [Alpha]-defensin peptides require activation for bactericidal activity. In mouse small intestine, matrilysin colocalized with [Alpha]-defensins (cryptdins) in Paneth cell granules, and in vitro it cleaved...

• The Role of probiotic lactobacillus plantarum IS 20506 on Occludin and ZO-1 of intestinal tight junctions rehabilitation

  Authors:Reza Ranuh, M.S. Subijanto, Ingrid Surono, and Aulanii'amFrom:Advances in Natural and Applied Sciences (Vol. 7, Issue 5) Peer-Reviewed

  Dec. 20131,287 words Report 1360LTight junctions (TJs) are cell-cell adhesion belts that encircle epithelial and endothelial cells at the limit between the apical and lateral membrane. Occludin and ZO-1 are the most important for TJs structures and...

• Transgenic milk containing recombinant human lactoferrin modulates the intestinal flora in piglets

  Authors:Wenping Hu, Jie Zhao, Jianwu Wang, Tian Yu, Jing Wang, and Ning LiFrom:Biochemistry and Cell Biology (Vol. 90, Issue 3) Peer-Reviewed

  June 20126,007 words Report 1390LLactoferrin (LF) is a beneficial multifunctional protein in milk. The objective of this study was to determine whether bovine transgenic milk containing recombinant human lactoferrin (rhLF) can modulate intestinal flora...

• Subepithelial telocytes are an important source of Wnts that supports intestinal crypts

  Authors:Michal Shoshkes-Carmel, Yue J. Wang, Kirk J. Wangensteen, Beata Toth, Ayano Kondo, Efi E. Massassa, et al.From:Nature (Vol. 557, Issue 7706) Peer-Reviewed

  May 20185,602 words Report 1560LTissues that undergo rapid cellular turnover, such as the mammalian haematopoietic system or the intestinal epithelium, are dependent on stem and progenitor cells that proliferate to provide differentiated cells to...

• Debate over the identity of an intestinal niche-cell population settled

  Author:Linda C. SamuelsonFrom:Nature (Vol. 558, Issue 7708) Peer-Reviewed

  June 20181,551 words Article 1430LThe cellular microenvironment required to sustain adult intestinal stem cells has long been controversial. Cells that release proteins needed for intestinal-tissue renewal have now been defined. The cellular...

• Effects of Escherichia coli Nissle 1917 and Ciprofloxacin on small intestinal epithelial cell mRNA expression in the neonatal piglet model of human rotavirus infection

  Authors:Francine C. Paim, Stephanie N. Langel, David D. Fischer, Sukumar Kandasamy, Lulu Shao, Moyasar A. Alhamo, et al.From:Gut Pathogens (Vol. 8, Issue 1) Peer-Reviewed

  Dec. 13, 20164,392 words Report 1580LWe evaluated the effects of the probiotic Escherichia coli Nissle 1917 (EcN) and the antibiotic Ciprofloxacin (Cipro) on mRNA expression of intestinal epithelial cells (IEC) in gnotobiotic (Gn) piglets colonized with a...