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    Academic Journals

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• Reconstruction and inference of the Lactococcus lactis MG1363 gene co-expression network

  Authors:Jimmy Omony, Anne de Jong, Jan Kok, and Sacha A. F. T. van HijumFrom:PLoS ONE (Vol. 14, Issue 5) Peer-Reviewed

  May 22, 20196,509 words Report 1550LLactic acid bacteria are Gram-positive bacteria used throughout the world in many industrial applications for their acidification, flavor and texture formation attributes. One of the species, Lactococcus lactis, is...

• Oral immunization with recombinant Lactococcus lactis confers protection against respiratory pneumococcal infection

  Authors:Julio Villena, Marcela Medina, Raul Raya, and Susana AlvarezFrom:Canadian Journal of Microbiology (Vol. 54, Issue 10) Peer-Reviewed

  Oct. 20085,360 words Clinical report In the present work, we evaluated if oral immunization with the pneumococcal protective protein A (PppA), expressed in the cell wall of Lactococcus lactis (L. lactis PppA+), was able to confer protective immunity...

• PBP2b plays a key role in both peripheral growth and septum positioning in Lactococcus lactis

  Authors:Blandine David, Marie-Clemence Duchene, Gabrielle Laurie Haustenne, Daniel Perez-Nunez, Marie-Pierre Chapot-Chartier, Xavier De Bolle, et al.From:PLoS ONE (Vol. 13, Issue 5) Peer-Reviewed

  May 23, 201810,751 words Report 1500LLactococcus lactis is an ovoid bacterium that forms filaments during planktonic and biofilm lifestyles by uncoupling cell division from cell elongation. In this work, we investigate the role of the leading peptidoglycan...

• Lactococcus lactis subsp. lactis infection in waterfowl: first confirmation in animals. (Dispatches)

  Authors:Joaquin Goyache, Ana I. Vela, Alicia Gibello, Maria M. Blanco, Victor Briones, Sergio Gonzalez, et al.From:Emerging Infectious Diseases (Vol. 7, Issue 5) Peer-Reviewed

  September-October 20011,768 words Article We report the first description, confirmed by bacteriologic and molecular (polymerase chain reaction and pulsed-field gel electrophoresis) analysis, of an infection in animals caused by Lactococcus lactis subsp. lactis,...

• Stimulation of respiratory immunity by oral administration of Lactococcus lactis

  Authors:Julio Villena, Marcela Medina, Elisa Vintini, and Susana AlvarezFrom:Canadian Journal of Microbiology (Vol. 54, Issue 8) Peer-Reviewed

  Aug. 20085,035 words Report 1470LAbstract: This work demostrates that nonrecombinant Lactococcus lactis NZ, administered by the oral route at the proper dose, is able to improve resistance against pneumococcal infection. Lactococcus lactis NZ oral...

• Molecular characterization of a recombinant manganese superoxide dismutase from Lactococcus lactis M4

  Authors:Boon Hooi Tan, Thean Chor Leow, Hooi Ling Foo, and Raha Abdul RahimFrom:BioMed Research InternationalPeer-Reviewed

  Annual 20145,296 words Report 1450LA superoxide dismutase (SOD) gene of Lactococcus lactis M4 was cloned and expressed in a prokaryotic system. Sequence analysis revealed an open reading frame of 621 bp which codes for 206 amino acid residues. Expression...

• Prenatal exposure to the probiotic Lactococcus lactis decreases anxiety-like behavior and modulates cortical cytoarchitecture in a sex specific manner.

  Authors:Natalia Surzenko, Eneda Pjetri, Carolyn A. Munson, Walter B. Friday, Jonas Hauser, Ellen Siobhan Mitchell, et al.From:PLoS ONE (Vol. 15, Issue 7) Peer-Reviewed

  July 9, 20206,997 words Report 1410LDevelopment of the cerebral cortex may be influenced by the composition of the maternal gut microbiota. To test this possibility, we administered probiotic Lactococcus lactis in drinking water to mouse dams from day 10.5...

• Oral Administration of Lactococcus lactis Subsp. lactis JCM5805 Enhances Lung Immune Response Resulting in Protection from Murine Parainfluenza Virus Infection

  Authors:Kenta Jounai, Tetsu Sugimura, Konomi Ohshio, and Daisuke FujiwaraFrom:PLoS ONE (Vol. 10, Issue 3) Peer-Reviewed

  Mar. 6, 20156,697 words Report 1420LWhen activated by viral infection, plasmacytoid dendritic cells (pDCs) play a primary role in the immune response through secretion of IFN-[alpha]. Lactococcus lactis subsp. lactis JCM5805 (JCM5805) is a strain of...

• Display of the viral epitopes on Lactococcus lactis: a model for food grade vaccine against EV71

  Authors:Nadimpalli Ravi S. Varma, Haryanti Toosa, Hooi Ling Foo, Noorjahan Banu Mohamed Alitheen, Mariana Nor Shamsudin, Ali S. Arbab, et al.From:Biotechnology Research InternationalPeer-Reviewed

  Annual 20135,763 words Report 1500LIn this study, we have developed a system for display of antigens of Enterovirus type 71 (EV71) on the cell surface of L. lactis. The viral capsid protein (VP1) gene from a local viral isolate was utilized as the...

• Effects of heme oxygenase-1 recombinant Lactococcus lactis on the intestinal barrier of hemorrhagic shock rats

  Authors:X.Y. Gao, X.F. Zhou, H. Wang, N. Lv, Y. Liu, and J.R. GuoFrom:Brazilian Journal of Medical and Biological Research (Vol. 50, Issue 7) Peer-Reviewed

  July 20173,680 words Report 1350LThis study aimed to investigate the effects of heme oxygenase-1 recombinant Lactococcus lactis (LL-HO-1) on the intestinal barrier of rats with hemorrhagic shock. One hundred Sprague-Dawley male rats (280-320 g) were...

• The Nanomechanical Properties of Lactococcus lactis Pili Are Conditioned by the Polymerized Backbone Pilin

  Authors:Mickael Castelain, Marie-Pierre Duviau, Alexis Canette, Philippe Schmitz, Pascal Loubiere, Muriel Cocaign-Bousquet, et al.From:PLoS ONE (Vol. 11, Issue 3) Peer-Reviewed

  Mar. 24, 20169,311 words Report 1470LPili produced by Lactococcus lactis subsp. lactis are putative linear structures consisting of repetitive subunits of the major pilin PilB that forms the backbone, pilin PilA situated at the distal end of the pilus, and...

• Clear plaque mutants of lactococcal phage TP901-1

  Authors:Witold Kot, Mogens Kilstrup, Finn K. Vogensen, and Karin HammerFrom:PLoS ONE (Vol. 11, Issue 6) Peer-Reviewed

  June 3, 20165,496 words Report 1520LWe report a method for obtaining turbid plaques of the lactococcal bacteriophage TP901-1 and its derivative TP901-BC1034. We have further used the method to isolate clear plaque mutants of this phage. Analysis of 8 such...

• Eliker-trimethoprim medium: a new selective tool for the isolation and growth of Lactococcus species

  Authors:Senouci Djamal Eddine, Benatia Saliha, Bensaid Nacera, Guessas Battache, Heddadji Miloud, and Kihal MebroukFrom:Advances in Environmental Biology (Vol. 10, Issue 1) Peer-Reviewed

  Jan. 20163,613 words Report 1350LLactic acid bacteria are phenotypically a very heterogeneous group. This group is characterized by the type of common criteria Gram positive, absence of catalase producing mainly lactic acid. The genus Lactococcus...

• Synergy at work: linking the metabolism of two lactic acid bacteria to achieve superior production of 2-butanol

  Authors:Mette J. Mar, Joakim M. Andersen, Vijayalakshmi Kandasamy, Jianming Liu, Christian Solem, and Peter R. JensenFrom:Biotechnology for Biofuels (Vol. 13, Issue 1) Peer-Reviewed

  Mar. 11, 20205,218 words Report 1490LBackground The secondary alcohol 2-butanol has many important applications, e.g., as a solvent. Industrially, it is usually made by sulfuric acid-catalyzed hydration of butenes. Microbial production of 2-butanol has...

• Synbiotic-like effect of linoleic acid overproducing Lactobacillus casei with berry phenolic extracts against pathogenesis of enterohemorrhagic Escherichia coli

  Authors:Zajeba Tabashsum, Mengfei Peng, Cassendra Bernhardt, Puja Patel, Michael Carrion, and Debabrata BiswasFrom:Gut Pathogens (Vol. 11, Issue 1) Peer-Reviewed

  July 27, 20194,841 words Report 1800LBackground Majority of enteric infections are foodborne and antimicrobials including antibiotics have been used for their control and treatment. However, probiotics or prebiotics or their combination offer a...

• In vivo delivery of pPERDBY to BALB/c mice by LacVax.sup.[R]DNA-I and comparison of elicited immune response with conventional immunization methods

  Authors:Bhrugu Yagnik, Drashya Sharma, Harish Padh, and Priti DesaiFrom:Gene Therapy (Vol. 25, Issue 7) Peer-Reviewed

  Oct. 20187,162 words Report 1310LThe non-invasive food grade Lactococcus lactis (L. lactis) represents a safe and attractive alternative to invasive pathogens for the delivery of plasmid DNA at mucosal sites. We have earlier shown the DNA delivery...

• The circle to lariat ratio of the Ll.LtrB group II intron from Lactococcus lactis is greatly influenced by a variety of biological determinants in vivo

  Authors:Caroline Monat and Benoit CousineauFrom:PLoS ONE (Vol. 15, Issue 8) Peer-Reviewed

  Aug. 18, 20207,187 words Report 1590LAuthor(s): Caroline Monat, Benoit Cousineau * Introduction Group II introns are large ribozymes that share a complex but universally conserved RNA secondary structure composed of six domains (DI-DVI) linked...

• Large chromosomal inversion correlated with spectinomycin resistance in Lactococcus lactis subsp. lactis bv. diacetylactis S50

  Authors:Milan Kojic, Branko Jovcic, Jelena Begovic, Djordje Fira, and Ljubisa TopisirovicFrom:Canadian Journal of Microbiology (Vol. 54, Issue 2) Peer-Reviewed

  Feb. 20083,600 words Article 1530LAbstract: A large chromosomal inversion that confers resistance to high concentrations of the antibiotic spectinomycin in Lactococcus lactis subsp. lactis bv. diacetylactis S50 was identified by pulsed field gel...

• Generation of dipeptidyl peptidase-IV-inhibiting peptides from [beta]-lactoglobulin secreted by Lactococcus lactis

  Authors:Suguru Shigemori, Kazushi Oshiro, Pengfei Wang, Yoshinari Yamamoto, Yeqin Wang, Takashi Sato, et al.From:BioMed Research InternationalPeer-Reviewed

  Annual 20143,960 words Report 1320LPrevious studies showed that hydrolysates of [beta]-lactoglobulin (BLG) prepared using gastrointestinal proteases strongly inhibit dipeptidyl peptidase-IV (DPP-IV) activity in vitro. In this study, we developed a...

• Plasmid Complement of Lactococcus lactis NCDO712 Reveals a Novel Pilus Gene Cluster

  Authors:Mariya Tarazanova, Marke Beerthuyzen, Roland Siezen, Marcela M. Fernandez-Gutierrez, Anne de Jong, Sjoerd van der Meulen, et al.From:PLoS ONE (Vol. 11, Issue 12) Peer-Reviewed

  Dec. 12, 201610,492 words Report 1490LLactococcus lactis MG1363 is an important gram-positive model organism. It is a plasmid-free and phage-cured derivative of strain NCDO712. Plasmid-cured strains facilitate studies on molecular biological aspects, but...