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Academic Journals
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From:Archives of Disease in Childhood (Vol. 85, Issue 4) Peer-ReviewedAbstract Aims--To examine the clinical and biological features of acute lymphoblastic leukaemia in children with Down's syndrome (DS), to compare their survival with other children, and to determine if entry to...
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From:Science (Vol. 246, Issue 4937) Peer-ReviewedAcute lymphoblastic leukemia (ALL) of the non-T type is the most common leukemia in children. A living (in vivo) animal model for studying the growth and progression of ALL was devised using a special strain of mice....
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From:Bone Marrow Transplantation (Vol. 56, Issue Suppl 1) Peer-ReviewedAuthor Affiliations: 14 - 17 March, 2021 * Virtual Meeting Copyright: Modified and published with permission from https://www.ebmt.org/annual-meeting Sponsorship Statement: Publication of this supplement is...
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From:Leukemia (Vol. 28, Issue 3) Peer-ReviewedHistone deacetylase (HDAC) inhibitors (HDACis) are well-characterized anti-cancer agents with promising results in clinical trials. However, mechanistically little is known regarding their selectivity in killing...
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From:BMC Research Notes (Vol. 15, Issue 1) Peer-ReviewedObjective Acute lymphoblastic leukemia (ALL) is one of the most common cancers in children for which the exact pathogenesis is not yet known. Single-nucleotide variants (SNVs) in different DNA repair genes are reported...
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From:Patient Care (Vol. 22, Issue 16) Peer-ReviewedThe outlook for adults who develop leukemia is improved; but treatment protocols are investigational, and regimens must be individualized. Here is what to expect from your oncologist and how to help....
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From:Expert Review of Anticancer Therapy (Vol. 3, Issue 3) Peer-ReviewedGiven the recent advances in the treatment of hematologic malignancies and the many other treatments on the horizon, physicians and payers will be faced with the critical decisions of when to use new treatments in the...
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From:Leukemia (Vol. 28, Issue 4) Peer-ReviewedCreated in 2001 and retained in 2008, the World Health Organization (WHO) now recognizes a distinct category of myelodysplastic/myeloproliferative neoplasms (MDS/MPN) for those patients diagnosed with clinical,...
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From:African Journal of Medical and Health Sciences (Vol. 12, Issue 2) Peer-ReviewedByline: Kaumudee. Pattnaik, Asaranti. Kar, Sabita. Palai, Bibudhendu. Pati, Chandrasekhar. Mohapatra Chronic myeloid leukemia (CML) is a rare hematological malignancy in children. The more common acute lymphoblastic...
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From:Leukemia (Vol. 25, Issue 8) Peer-ReviewedChildren with Down Syndrome (DS) have an increased risk of developing leukemia, including both acute myeloid (ML-DS) and acute lymphoblastic leukemia (DS ALL). (1) These leukemias differ in clinical characteristics and...
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From:Archives of Disease in Childhood (Vol. 89, Issue 4) Peer-ReviewedIntroduction: New trends for the treatment of childhood acute myeloblastic and lymphoblastic leukaemia (AML, ALL) include more aggressive schedules whose effects on the immunisation status remain unknown. Method: As...
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From:Science (Vol. 223) Peer-ReviewedChildhood Leukemia and Fallout from the Nevada Nuclear Tests In 1979 Lyon et al. (1) reported an association between increased risk of mortality from childhood leukemia and residence in the southern 17 counties of...
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From:Oncology Nursing Forum (Vol. 42, Issue 5) Peer-ReviewedPurpose/Objectives: To examine associations among oxidative stress, fine and visual-motor abilities, and behavioral adjustment in children receiving chemotherapy for acute lymphoblastic leukemia (ALL). Design: A...
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From:Obesity, Fitness & Wellness Week2017 MAY 20 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- GlycoMimetics, Inc. (NASDAQ: GLYC) announced the publication of results from a preclinical study that showed its drug...
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From:Leukemia (Vol. 28, Issue 4) Peer-ReviewedTo date, more than 500 fusion genes have been described in hematological malignancies, yet only a small fraction of these are sufficiently common, and with a known clinical impact, to justify routine clinical analysis....
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From:Oncology Letters (Vol. 13, Issue 4) Peer-ReviewedAbstract. Granulocyte colony-stimulating factor (G-CSF) mobilizes regulatory T cells (Tregs) from bone marrow into the peripheral blood, by reducing the expression of stromal cell-derived factor-1[alpha] (SDF-1[alpha])....
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From:Leukemia (Vol. 24, Issue 1) Peer-ReviewedWe have recently shown that constitutive activation of PI3K/Akt signaling pathway is a very common event in pediatric T-cell acute lymphoblastic leukemia (T-ALL) and is critical for leukemic cell viability. PI3K/Akt...
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From:Leukemia (Vol. 26, Issue 7) Peer-ReviewedAlthough the overall prognosis in childhood acute lymphoblastic leukemia (ALL) is good, outcome after relapse is poor. Recurrence is frequently characterized by the occurrence of disease at extramedullary sites, such as...
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From:Indian Journal of Medical and Paediatric Oncology (Vol. 41, Issue 1) Peer-ReviewedByline: Mahmood. Al-Mendalawi Sir, In October-December 2018 issue of the Indian Journal of Medical and Paediatric Oncology , Anoop et al .[1] described a case of concurrent hairy cell leukemia (HCL) and chronic...
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From:Leukemia (Vol. 22, Issue 12) Peer-ReviewedThe aim of the study was to analyze the impact of minimal residual disease (MRD) after reinduction therapy on the outcome of children with relapsed 'high-risk' acute lymphoblastic leukemia (ALL). Sixty patients with...