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From:Mayo Clinic Proceedings (Vol. 97, Issue 1) Peer-ReviewedA75-year-oId woman presented to the emergency department with a 1-year history of worsening loose stools and abdominal discomfort. Over the course of the year, the patient had experienced regular cycles of liquid stool...
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From:American Family Physician (Vol. 103, Issue 10) Peer-ReviewedKey Points for Practice * The KIDs List includes a limited number of medications to avoid or use with caution in children older than one year. More medications are included for infants and neonates. * Medications...
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From:Formulary (Vol. 48, Issue 1) Peer-ReviewedLinzess Linaclotide IRONWOOD PHARMACEUTICALS AND FOREST PHARMACEUTICALS A guanylate cyclase-C agonist indicated for the treatment of chronic idiopathic constipation and irritable bowel syndrome with...
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From:Expert Review of Gastroenterology & Hepatology (Vol. 7, Issue 5s1) Peer-ReviewedAuthor(s): Jan Tack [*] 1 Keywords : abdominal pain; bloating; constipation; European Medicines Agency; gender; irritable bowel syndrome; linaclotide; quality of life Patients with irritable bowel syndrome...
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From:Family Practice News (Vol. 42, Issue 15)The Food and Drug Administration approved linaclotide on Aug. 30 to treat two conditions: chronic idiopathic constipation and irritable bowel syndrome with constipation in adults. Linaclotide (Linzess) is...
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From:PLoS ONE (Vol. 10, Issue 7) Peer-ReviewedBackground Abdominal bloating is a common and bothersome symptom of chronic idiopathic constipation. The objective of this trial was to evaluate the efficacy and safety of linaclotide in patients with chronic...
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From:Journal of Family Practice (Vol. 69, Issue 7) Peer-ReviewedCONTINUING MEDICAL EDUCATION LEARNING OBJECTIVES * Describe the multiple symptoms of irritable bowel syndrome (IBS) and their impact on quality of life * Use a staged strategy for the diagnostic evaluation of IBS...
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From:Formulary (Vol. 47, Issue 1) Peer-ReviewedAbstract Constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation affect millions of Americans. Patients diagnosed with these conditions experience adverse symptoms that can have a negative...
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From:Formulary (Vol. 47, Issue 10) Peer-ReviewedLinaclotide (Linzess, Ironwood Pharmaceuticals and Forest) was approved to treat chronic idiopathic constipation and to treat irritable bowel syndrome with constipation (IBS-C) in adults....
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From:MPR Pharmacists' Edition (Vol. 7, Issue 1)Companies: Forest and Ironwood Rx Pharmacologic class: Guanylate cyclase-C agonist Active ingredient: Linaclotide 145mcg, 290mcg; capsules. Indications: Irritable bowel syndrome with constipation (IBS-C)....