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    Academic Journals

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• Lipopolysaccharide rolls out the barrel

  Author:Russell E. BishopFrom:Nature (Vol. 511, Issue 7507) Peer-Reviewed

  July 3, 20141,253 words Report 1650LTwo crystal structures of the LptD-LptE protein complex reveal how the cell-wall component lipopolysaccharide is delivered and inserted into the external leaflet of the bacterial outer membrane. The inner membrane of...

• Galantamine protects against lipopolysaccharide-induced acute lung injury in rats

  Authors:G. Li, C.L. Zhou, Q.S. Zhou, and H.D. ZouFrom:Brazilian Journal of Medical and Biological Research (Vol. 49, Issue 2) Peer-Reviewed

  Feb. 20164,670 words Report 1400LLipopolysaccharide (LPS)-induced endotoxemia triggers the secretion of proinflammatory cytokines and can cause acute lung injury (ALI). The high mobility group box 1 (HMGB1) protein plays an important role as a late...

• Translocator protein ligand, YL-IPA08, attenuates lipopolysaccharide-induced depression-like behavior by promoting neural regeneration

  Authors:Xiao-Ying Zhang, Li-Ming Zhang, Wei-Dong Mi, and Yun-Feng LiFrom:Neural Regeneration Research (Vol. 13, Issue 11) Peer-Reviewed

  Nov. 20186,042 words Report 1220LByline: Xiao-Ying. Zhang, Li-Ming. Zhang, Wei-Dong. Mi, Yun-Feng. Li Translocator protein has received attention for its involvement in the pathogenesis of depression. This study assessed the effects of the new...

• Limited differential expression of miRNAs and other small RNAs in LPS-stimulated human monocytes.

  Authors:Daniel Lu, Tracy Yamawaki, Hong Zhou, Wen-Yu Chou, Mark Chhoa, Edwin Lamas, et al.From:PLoS ONE (Vol. 14, Issue 3) Peer-Reviewed

  Mar. 25, 20199,914 words Report 1640LMonocytes are a distinct subset of myeloid cells with diverse functions in early inflammatory immune modulation. While previous studies have surveyed the role of miRNA regulation on different myeloid cell lines and...

• Neonatal endotoxin stimulation is associated with a long-term bronchiolar epithelial expression of innate immune and anti-allergic markers that attenuates the allergic response

  Authors:Luciana Noemi Garcia, Carolina Leimgruber, Juan Pablo Nicola, Amado Alfredo Quintar, Cristina Alicia Maldonado, and Svetlana P. ChapovalFrom:PLoS ONE (Vol. 15, Issue 5) Peer-Reviewed

  May 7, 20208,388 words Report 1550LAuthor(s): Luciana Noemi García 1,2,*, Carolina Leimgruber 2, Juan Pablo Nicola 3,4, Amado Alfredo Quintar 1,2, Cristina Alicia Maldonado 1,2 Introduction Asthma is a heterogeneous disease with diverse underlying...

• Anti-inflammatory effect of combination of Scutellariae Radix and Liriopis Tuber water extract

  Authors:Mi-Hye So and You-Kyung ChoiFrom:Evidence - Based Complementary and Alternative Medicine (Vol. 2015) Peer-Reviewed

  Annual 20155,327 words Report 1560LScutellariae Radix and Liriopis Tuber have been used to treat the inflammatory diseases in traditional Korean medicine and anti-inflammatory effect of each herb has been shown partially in several articles. However, the...

• Effect of Inulin on Proteome Changes Induced by Pathogenic Lipopolysaccharide in Human Colon

  Authors:Michele Pier Luca Guarino, Annamaria Altomare, Simone Barera, Vittoria Locato, Silvia Cocca, Cinzia Franchin, et al.From:PLoS ONE (Vol. 12, Issue 1) Peer-Reviewed

  Jan. 9, 20177,106 words Report 1570LIn the present study, the protective role of inulin against lipopolysaccharide (LPS)-induced oxidative stress was evaluated on human colonic mucosa using a proteomic approach. Human colonic mucosa and submucosa were...

• Differential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen

  Authors:Peter J. Hart, Colette M. O'Shaughnessy, Matthew K. Siggins, Saeeda Bobat, Robert A. Kingsley, David A. Goulding, et al.From:PLoS ONE (Vol. 11, Issue 1) Peer-Reviewed

  Jan. 7, 20168,468 words Report 1290LSalmonella enterica serovar Typhi expresses a capsule of Vi polysaccharide, while most Salmonella serovars, including S. Enteritidis and S. Typhimurium, do not. Both S. Typhi and S. Enteritidis express the...

• Lipopolysaccharide potentiates platelet responses via toll-like receptor 4-stimulated Akt-Erk-PLA.sub.2 signalling

  Authors:Maria E. Lopes Pires, Simon R. Clarke, Sisi Marcondes, and Jonathan M. GibbinsFrom:PLoS ONE (Vol. 12, Issue 11) Peer-Reviewed

  Nov. 14, 20178,971 words Report 1480LLipopolysaccharide (LPS) from the cell envelope of Gram-negative bacteria is a principal cause of the symptoms of sepsis. LPS has been reported to modulate the function of platelets although the underlying mechanisms of...

• Characterization of basal and lipopolysaccharide-induced microRNA expression in equine peripheral blood mononuclear cells using Next-Generation Sequencing

  Authors:Nicholas J. Parkinson, Virginia A. Buechner-Maxwell, Sharon G. Witonsky, R. Scott Pleasant, Stephen R. Werre, and S. Ansar AhmedFrom:PLoS ONE (Vol. 12, Issue 5) Peer-Reviewed

  May 26, 20179,871 words Report 1500LThe innate immune response to lipopolysaccharide contributes substantially to the morbidity and mortality of gram-negative sepsis. Horses and humans share an exquisite sensitivity to lipopolysaccharide and thus the...

• Dexmedetomidine reduces lipopolysaccharide induced neuroinflammation, sickness behavior, and anhedonia

  Authors:Ching-Hua Yeh, Liang-Po Hsieh, Ming-Chung Lin, Tsui-Shan Wei, Hui-Ching Lin, Chia-Cheng Chang, et al.From:PLoS ONE (Vol. 13, Issue 1) Peer-Reviewed

  Jan. 19, 20186,392 words Report 1290LAuthor(s): Ching-Hua Yeh 1,2,3, Liang-Po Hsieh 1,4, Ming-Chung Lin 5, Tsui-Shan Wei 3, Hui-Ching Lin 6,7, Chia-Cheng Chang 3,5, Chung-Hsi Hsing 3,5,* Introduction The symptoms of sickness, such as the loss of...

• Effects of propofol on lipopolysaccharide-induced expression and release of HMGB1 in macrophages

  Authors:T. Wang, X.Y. Wei, B. Liu, L.J. Wang, and L.H. JiangFrom:Brazilian Journal of Medical and Biological Research (Vol. 48, Issue 4) Peer-Reviewed

  Apr. 20153,889 words Report 1420LThis study aimed to determine the effects of different concentrations of propofol (2,6-diisopropylphenol) on lipopolysaccharide (LPS)-induced expression and release of high-mobility group box 1 protein (HMGB1) in mouse...

• Protein Phosphatase 2A in Lipopolysaccharide-Induced Cyclooxygenase-2 Expression in Murine Lymphatic Endothelial Cells

  Authors:Yu-Fan Chuang, Mei-Chieh Chen, Shiu-Wen Huang, Ya-Fen Hsu, George Ou, Yu-Jou Tsai, et al.From:PLoS ONE (Vol. 10, Issue 8) Peer-Reviewed

  Aug. 28, 20158,254 words Report 1340LThe lymphatic endothelium plays an important role in the maintenance of tissue fluid homeostasis. It also participates in the pathogenesis of several inflammatory diseases. However, little is known about the underlying...

• Very low concentration of lipopolysaccharide can induce the production of various cytokines and chemokines in human primary monocytes.

  Authors:Ratthakorn Chaiwut and Watchara KasinrerkFrom:BMC Research Notes (Vol. 15, Issue 1) Peer-Reviewed

  Feb. 10, 20223,190 words Report 1330LObjective Lipopolysaccharide (LPS), a component of gram-negative bacteria, is a potent innate immune stimulus. The interaction of LPS with innate immune cells induces the production of proinflammatory cytokines and...

• Activation of the [beta]-adrenergic receptor exacerbates lipopolysaccharide-induced wasting of skeletal muscle cells by increasing interleukin-6 production.

  Authors:Shino Matsukawa, Shinichi Kai, Hideya Seo, Kengo Suzuki, and Kazuhiko FukudaFrom:PLoS ONE (Vol. 16, Issue 5) Peer-Reviewed

  May 18, 20217,397 words Report 1460LThe skeletal muscle mass has been shown to be affected by catecholamines, such as epinephrine (Epi), norepinephrine (NE), and isoproterenol (ISO). On the other hand, lipopolysaccharide (LPS), one of the causative...

• Distinct biological activity of lipopolysaccharides with different lipid A acylation status from mutant strains of Yersinia pestis and some members of genus Psychrobacter

  Authors:K.V. Korneev, A.N. Kondakova, N.P. Arbatsky, K.A. Novototskaya-Vlasova, E.M. Rivkina, A.P. Anisimov, et al.From:Biochemistry (Moscow) (Vol. 79, Issue 12) Peer-Reviewed

  Dec. 20143,383 words Report 1530LCorrelation between the chemical structure of lipid A from various Gram-negative bacteria and biological activity of their lipopolysaccharide (LPS) as an agonist of the innate immune receptor Toll-like receptor 4 was...

• Effect of penehyclidine hydrochloride on [beta]-arrestin-1 expression in lipopolysaccharide-induced human pulmonary microvascular endothelial cells

  Authors:J. Zhan, F. Xiao, Z.Z. Zhang, Y.P. Wang, K. Chen, and Y.L. WangFrom:Brazilian Journal of Medical and Biological Research (Vol. 46, Issue 12) Peer-Reviewed

  Dec. 20133,473 words Report 1450L[beta]-arrestins are expressed proteins that were first described, and are well-known, as negative regulators of G protein-coupled receptor signaling. Penehyclidine hydrochloride (PHC) is a new anti-cholinergic drug...

• The Reaction Pathway of miR-30c-5p Activates Lipopolysaccharide Promoting the Course of Traumatic and Hemorrhagic Shock Acute Lung Injury.

  Authors:Jianmin Li, Chanyuan Pan, Chao Tang, Wenwen Tan, Hui Liu, and Jing GuanFrom:BioMed Research International (Vol. 2022) Peer-Reviewed

  Apr. 13, 20223,915 words Report 1440LAcute lung injury (ALI) is an acute hypoxic respiratory failure caused by diffuse inflammatory injury in alveolar epithelial cells during severe infection, trauma, and shock. Among them, trauma/hemorrhagic shock (T/HS)...

• Starve a fever, feed the microbiota: a study finds that the cells lining the gut are modified in response to systemic infection, increasing the host's tolerance to infection in a manner that is dependent on the microorganisms that inhabit the gut

  Authors:Seth Rakoff-Nahoum and Laurie E. ComstockFrom:Nature (Vol. 514, Issue 7524) Peer-Reviewed

  Oct. 30, 20141,069 words Article 1550LMammals have a mutualistic relationship with the consortium of microorganisms that inhabit their intestines, collectively known as the gut microbiota. The microbiota profits from an environment that is rich in dietary...

• Quercetin reduces hydroxyurea induced cytotoxicity in immortalized mouse aortic endothelial cells

  Authors:Zachary M. Kiser, Monica D.M. McGee, Racquel J. Wright, Alexander Quarshie, Gale W. Newman, Karen R. Randall, et al.From:PeerJ (Vol. 5) Peer-Reviewed

  May 31, 20174,075 words Report 1330LBackground Chronic inflammation is a characteristic of sickle cell disease (SCD), and is invariably associated with vascular endothelial injury. Hydroxyurea (HU), a naturally cytotoxic chemotherapeutic agent, is the...