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• Select Quantitative Detection of Borrelia burgdorferi sensu lato in Erythema Migrans Skin Lesions Using Internally Controlled Duplex Real Time PCR

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  Quantitative Detection of Borrelia burgdorferi sensu lato in Erythema Migrans Skin Lesions Using Internally Controlled Duplex Real Time PCR

  Authors:Maria O'Rourke, Andreas Traweger, Lara Lusa, Dasa Stupica, Vera Maraspin, P. Noel Barrett, et al.From:PLoS ONE (Vol. 8, Issue 5) Peer-Reviewed

  May 16, 20138,258 words Article 1610LB. burgdorferi sensu stricto, B. afzelii, B. garinii and B. bavariensis are the principal species which account for Lyme borreliosis (LB) globally. We have developed an internally controlled duplex quantitative real...
• Select Biting back at Lyme disease

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  Biting back at Lyme disease

  Author:John TravisFrom:Science (Vol. 256, Issue 5064) Peer-Reviewed

  June 19, 1992659 words Article As the summer heat rolls across the country, enticing people into the fields and forests, it brings with it the seasonal concern about Lyme disease. And although there isn't yet any surefire way to prevent the disease,...
• Select Lyme disease vaccine pulled due to lack of demand. (Too Many Shots)

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  Lyme disease vaccine pulled due to lack of demand. (Too Many Shots)

  Author:Winnie Anne ImperioFrom:Skin & Allergy News (Vol. 33, Issue 4)

  Apr. 2002184 words Brief article Lackluster demand has forced GlaxoSmithKline, maker of LYMErix, to pull the Lyme disease vaccine off the market. The company estimated that less than 10,000 people would seek vaccination this year, according to...
• Select New Vaccines for Infectious Diseases

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  New Vaccines for Infectious Diseases

  Authors:STEVE WATERMAN and CURTIS FRITZFrom:The Western Journal of Medicine (Vol. 169, Issue 6) Peer-Reviewed

  Dec. 1998785 words Article A new vaccine against rotavirus (RotaShield, Wyeth-Lederle) has recently been licensed by the FDA. Licensure is expected for a new vaccine against Lyme disease in early 1999. Both vaccines will pose challenges to...
• Select The need for a new vaccine against lyme borreliosis

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  The need for a new vaccine against lyme borreliosis

  Authors:P. Noel Barrett and Daniel PortsmouthFrom:Expert Review of Vaccines (Vol. 12, Issue 2) Peer-Reviewed

  Feb. 20131,681 words Editorial 1620LAuthor(s): P Noel Barrett 1 * , Daniel Portsmouth 2 Keywords : Borrelia; borreliosis; lyme; Osp; OspA; tick; vaccine Lyme borreliosis (LB) is a multisystem inflammatory disease caused by infection with...
• Select Lyme Disease Vaccine: Good for Dogs, Adults, and Children?

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  Lyme Disease Vaccine: Good for Dogs, Adults, and Children?

  Author:HENRY M. JR FEDERFrom:Pediatrics (Vol. 105, Issue 6) Peer-Reviewed

  June 20001,665 words Article ABBREVIATIONS. LD, Lyme disease; Osp A, outer surface protein A; ELISA, enzyme-linked immunosorbent assay. In 1977, Steere and colleagues[1] described a mysterious disease (in 39 children and 12 adults) characterized...
• Select Lyme Disease Test Works in Lymerix-Vaccinated Patients

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  Lyme Disease Test Works in Lymerix-Vaccinated Patients

  Author:Robert FinnFrom:Pediatric News (Vol. 35, Issue 9)

  Sept. 2001172 words Brief article The Food and Drug Administration has approved an enzyme-linked immunosorbent assay for detecting Lyme disease antibodies that does not yield false-positive results in those patients who have already been vaccinated with...
• Select The Cost Effectiveness of Vaccinating against Lyme Disease

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  The Cost Effectiveness of Vaccinating against Lyme Disease

  Authors:Martin I. Meltzer, David T. Dennis, and Kathleen A. OrloskiFrom:Emerging Infectious Diseases (Vol. 5, Issue 3) Peer-Reviewed

  May 19995,125 words Article To determine the cost effectiveness of vaccinating against Lyme disease, we used a decision tree to examine the impact on society of six key components. The main measure of outcome was the cost per case averted....
• Select Some Fear Lyme Vaccine May Lead to Autoimmune Arthritis

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  Some Fear Lyme Vaccine May Lead to Autoimmune Arthritis

  Author:NATHAN D. CHILDSFrom:Family Practice News (Vol. 29, Issue 12)

  June 15, 1999501 words Article NEW YORK -- Fears that the Lyme disease vaccine might trigger autoimmune arthritis loomed large at a meeting on the disease sponsored by the Lyme Disease Foundation. "I am concerned about the possible adverse effects...
• Select Findings from U. Pal and Co-Authors Broaden Understanding of Borrelia burgdorferi (Borrelia burgdorferi BBI39 Paralogs, Targets of Protective Immunity, Reduce Pathogen Persistence Either in Hosts or in the Vector)

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  Findings from U. Pal and Co-Authors Broaden Understanding of Borrelia burgdorferi (Borrelia burgdorferi BBI39 Paralogs, Targets of Protective Immunity, Reduce Pathogen Persistence Either in Hosts or in the Vector)

  From:Obesity, Fitness & Wellness Week

  June 17, 2017371 words Brief article 1570L2017 JUN 17 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- A new study on Gram-Negative Bacteria - Borrelia burgdorferi is now available. According to news reporting originating...
• Select Human Lyme disease vaccines: past and future concerns

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  Human Lyme disease vaccines: past and future concerns

  Authors:Dean T Nardelli, Erik L Munson, Steven M Callister, and Ronald F SchellFrom:Future Microbiology (Vol. 4, Issue 4)

  May 200910,647 words Report Author(s): Dean T Nardelli 1 , Erik L Munson 2 , Steven M Callister 3 , Ronald F Schell [[dagger]] 4 Keywords: Keywords Borrelia burgdorferi; Lyme disease; Lyme vaccine; OspA; OspC Lyme disease is a...
• Select Lyme disease vaccine doesn't cause inflammatory arthritis. (Preliminary Data)

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  Lyme disease vaccine doesn't cause inflammatory arthritis. (Preliminary Data)

  Author:Miriam E. TuckerFrom:Clinical Psychiatry News (Vol. 30, Issue 3)

  Mar. 2002271 words Brief article CHICAGO -- Exposure to Lyme disease vaccine did not increase the risk for inflammatory arthritis, based on preliminary data from a postmarketing study sponsored by GlaxoSmithKline Biologicals. Arthropathy codes...
• Select Clinical tests confirm effectiveness of Lyme disease vaccine

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  Clinical tests confirm effectiveness of Lyme disease vaccine

  From:Consultant (Vol. 38, Issue 11) Peer-Reviewed

  Nov. 1998806 words Article Two large scale clinical trials were conducted to determine the efficacy of a vaccine based on the outer-surface protein A of Borrelia burgdorferi, the causative organism. The investigators were A.C. Steere and coworkers...
• Select Progress and controversy surrounding vaccines against Lyme disease

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  Progress and controversy surrounding vaccines against Lyme disease

  Authors:Mark S. Hanson and Robert EdelmanFrom:Expert Review of Vaccines (Vol. 2, Issue 5) Peer-Reviewed

  Oct. 1, 200316,351 words Report Less than 20 years elapsed between the 1982 report of the identification and isolation of Borrelia burgdorferi and the licensure and marketing in the USA of a prophylactic vaccine against this pathogen. However, the...
• Select Researchers Submit Patent Application, "Method of Treating Central Nervous System Disorders with Borrelia Burgdorferi Antigen", for Approval (USPTO 20150320849)

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  Researchers Submit Patent Application, "Method of Treating Central Nervous System Disorders with Borrelia Burgdorferi Antigen", for Approval (USPTO 20150320849)

  From:Obesity, Fitness & Wellness Week

  Dec. 5, 20152,290 words Article 1550L2015 DEC 5 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- From Washington, D.C., NewsRx journalists report that a patent application by the inventor McMichael, John (Delanson,...
• Select Immunization with a Borrelia burgdorferi BB0172-Derived Peptide Protects Mice against Lyme Disease

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  Immunization with a Borrelia burgdorferi BB0172-Derived Peptide Protects Mice against Lyme Disease

  Authors:Christina M. Small, Dharani K. Ajithdoss, Aline Rodrigues Hoffmann, Waithaka Mwangi, and Maria D. Esteve-GassentFrom:PLoS ONE (Vol. 9, Issue 2) Peer-Reviewed

  Feb. 5, 20149,552 words Article 1470LAuthor(s): Christina M. Small, Dharani K. Ajithdoss **, Aline Rodrigues Hoffmann, Waithaka Mwangi, Maria D. Esteve-Gassent * Introduction Lyme disease (LD) is the most prevalent arthropod-borne infection in the...
• Select A systematic review and meta-analysis for the adverse effects, immunogenicity and efficacy of Lyme disease vaccines: guiding novel vaccine development

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  A systematic review and meta-analysis for the adverse effects, immunogenicity and efficacy of Lyme disease vaccines: guiding novel vaccine development

  Authors:Alaa Badawi, Maria Shering, Shusmita Rahman, and L. Robbin LindsayFrom:Canadian Journal of Public Health (Vol. 108, Issue 1) Peer-Reviewed

  January-February 20176,354 words Report 2030LBACKGROUND: Lyme borreliosis (LB) is the most prevalent arthropod-borne infectious disease in North America. Currently, no vaccine is available to prevent LB in humans, although monovalent and multivalent vaccines have...
• Select Tick saliva

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  Tick saliva

  From:The Science Teacher (Vol. 77, Issue 1) Peer-Reviewed

  Jan. 2010369 words Brief article 1360LA protein found in tick saliva helps protect mice from developing Lyme disease, Yale University researchers have discovered. The findings, published in Cell Host & Microbe, may spur development of a new vaccine for Lyme...
• Select A dog can get a Lyme disease immunization; why can't I?

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  A dog can get a Lyme disease immunization; why can't I?

  Author:Juanita A. CarnesFrom:Clinical Advisor (Vol. 14, Issue 2)

  Feb. 2011102 words Brief article, Lette... 970LWhy is there a canine Lyme disease immunization but nothing for humans?--JUANITA A. CARNES, FNP-BC, Westfield, Mass. A Lyme disease vaccine (LYMErix) was developed in the early 1990s and received FDA approval in...
• Select Safety and Immunogenicity of a Recombinant Borrelia burgdorferi Outer Surface Protein A Vaccine Against Lyme Disease in Healthy Children and Adolescents: A Randomized Controlled Trial

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  Safety and Immunogenicity of a Recombinant Borrelia burgdorferi Outer Surface Protein A Vaccine Against Lyme Disease in Healthy Children and Adolescents: A Randomized Controlled Trial

  Authors:Vijay K. Sikand, Neal Halsey, Peter J. Krause, Sunil K. Sood, Richard Geller, Christian Van Hoecke, et al.From:Pediatrics (Vol. 108, Issue 1) Peer-Reviewed

  July 20014,565 words Product/service eval... Objective. A recombinant lipoprotein outer surface protein A (OspA) Lyme disease (LD) vaccine (LYMErix) has been shown to be safe and effective in preventing LD in adults and in adolescents 15 years of age and older....