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    Academic Journals

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• Diagnosis and Prognosis of Prostate Cancer from Circulating Matrix Metalloproteinases and Inhibitors

  Authors:William Khalil El- Chaer, Clayton Franco Moraes, and Otavio Toledo NobregaFrom:Journal of Aging Research (Vol. 2018) Peer-Reviewed

  Annual 20182,677 words Report 1470LAlthough prostate cancer (PCa) is the sixth most common type of neoplasm in the world and the second in prevalence among men (10% of all cases), there is shortage of studies focused on primary prevention of the disorder...

• Rapid purification of a new P-I class metalloproteinase from Bothrops moojeni venom with antiplatelet activity

  Authors:Mayara R. de Queiroz, Carla C. Neves Mamede, Kelly C. Fonseca, Nadia C.G. de Morais, Bruna B. de Sousa, Norival A. Santos-Filho, et al.From:BioMed Research InternationalPeer-Reviewed

  Annual 20145,316 words Report 1360LThe present study aimed to evaluate the proteolytic and biological activities of a new metalloproteinase from B. moojeni venom. The purification of BmooMP[alpha]-II was carried out through two chromatographic steps...

• Association of Matrix Metalloproteinases -7, -8 and -9 and TIMP -1 with Disease Severity in Acute Pancreatitis. A Cohort Study

  Authors:Eija Nukarinen, Outi Lindstrom, Krista Kuuliala, Leena Kylanpaa, Ville Pettila, Pauli Puolakkainen, et al.From:PLoS ONE (Vol. 11, Issue 8) Peer-Reviewed

  Aug. 25, 20164,982 words Report 1390LObjectives Several biomarkers for early detection of severe acute pancreatitis (SAP) have been presented. Matrix metalloproteinases (MMP) and their tissue inhibitors (TIMP) are released early in inflammation. We...

• Senescent Expression of Genes Coding Tropoelastin, Elastase, Lysyl Oxidase, and Tissue Inhibitors of Metalloproteinases in Rat Vocal Folds: Comparison With Skin and Lungs

  Authors:Hu Ding and Steven D. GrayFrom:Journal of Speech, Language, and Hearing Research (Vol. 44, Issue 2) Peer-Reviewed

  Apr. 20015,304 words Article Histology studies indicate that vocal elastin content accumulates with age, suggesting passible contribution of elastin to age-associated voice changes. However, the underlying mechanism remains unclear. Using a...

• Unlocking the therapeutic potential of artificial metalloenzymes.

  Authors:Katsunori Tanaka and Kenward VongFrom:Japan Academy Proceedings Series B: Physical and Biological Sciences (Vol. 96, Issue 3) Peer-Reviewed

  Mar. 20207,966 words Article 1770LIn order to harness the functionality of metals, nature has evolved over billions of years to utilize metalloproteins as key components in numerous cellular processes. Despite this, transition metals such as ruthenium,...

• Expression and Distribution of Adam 9 (A Disintegrin And Metalloprotease) in the Developing Rat Heart

  Author:Natalie HardwickFrom:Bulletin of the South Carolina Academy of Science

  Annual 2001165 words Brief article The human heart begins developing early in gestation and lasts for a period of six weeks. Migration and proliferation of cells are essential to proper heart development. These processes are guided by the interactions...

• Structures of metal sites of oxidized bovine heart cytochrome c oxidase at 2.8 angstroms

  Authors:Tomitake Tsukihara, Hiroshi Aoyama, Eiki Yamashita, Takashi Tomizaki, Hiroshi Yamaguchi, Kyoko Shinzawa-Itoh, et al.From:Science (Vol. 269, Issue 5227) Peer-Reviewed

  Aug. 25, 19953,835 words Cover story The high resolution three-dimensional x-ray structure of the metal sites of bovine heart cytochrome c oxidase is reported. Cytochrome c oxidase is the largest membrane protein yet crystallized and analyzed at atomic...

• Estrogen deficiency modifies matrix metalloproteinases activity and vascular function of mesenteric arteries in female rats

  Authors:Hsin-Hsueh Shen, Mei-Hui Liao, Yu-Hui Chang, and Yen-Mei LeeFrom:Journal of Medical Sciences (Vol. 37, Issue 2) Peer-Reviewed

  March-April 20174,224 words Report 1860LByline: Hsin-Hsueh. Shen, Mei-Hui. Liao, Yu-Hui. Chang, Yen-Mei. Lee Objective: Estrogen possesses vasoprotective effects and its deficiency has been implicated in the pathogenesis of postmenopausal hypertension....

• Matrix metalloproteinase expression in human retinal microvascular cells

  Authors:Maria B. Grant, Sergio Caballero, Roy W. Tarnuzzer, Kathryn E. Bass, Alexander V. Ljubimov, Polyxenie E. Spoerri, et al.From:Diabetes (Vol. 47, Issue 8) Peer-Reviewed

  Aug. 19985,017 words Article The degree of hyperglycemia correlates with the development of diabetic retinopathy. We investigated the effect of glucose on the expression of matrix metalloproteinase (MMP)-2 and MMP-9 (72-kDa and 92-kDa type IV...

• Insulin suppresses plasma concentration of vascular endothelial growth factor and matrix metalloproteinase-9

  Authors:Paresh Dandona, Ahmad Aljada, Priya Mohanty, Husam Ghanim, Arindam Bandyopadhyay, and Ajay ChaudhuriFrom:Diabetes Care (Vol. 26, Issue 12) Peer-Reviewed

  Dec. 20033,116 words Article OBJECTIVE--We recently demonstrated a potent anti-inflammatory and thus a potential anti-atherogenic effect of insulin in human aortic endothelial cells and mononuclear cells at physiologically relevant concentrations....

• S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death. (Reports)

  Authors:Zezong Gu, Marcus Kaul, Boxu Yan, Steven J. Kridel, Jiankun Cui, Alex Strongin, et al.From:Science (Vol. 297, Issue 5584) Peer-Reviewed

  Aug. 16, 20022,645 words Article Matrix metalloproteinases (MMPs) are implicated in the pathogenesis of neurodegenerative diseases and stroke. However, the mechanism of MMP activation remains unclear. We report that MMP activation involves...

• Effects of PI and PIII Snake Venom Haemorrhagic Metalloproteinases on the Microvasculature: A Confocal Microscopy Study on the Mouse Cremaster Muscle

  Authors:Cristina Herrera, Mathieu-Benoit Voisin, Teresa Escalante, Alexandra Rucavado, Sussan Nourshargh, and Jose Maria GutierrezFrom:PLoS ONE (Vol. 11, Issue 12) Peer-Reviewed

  Dec. 16, 20168,714 words Report 1490LThe precise mechanisms by which Snake Venom Metalloproteinases (SVMPs) disrupt the microvasculature and cause haemorrhage have not been completely elucidated, and novel in vivo models are needed. In the present study,...

• Evaluation of Alpha 1-Antitrypsin and the Levels of mRNA Expression of Matrix Metalloproteinase 7, Urokinase Type Plasminogen Activator Receptor and COX-2 for the Diagnosis of Colorectal Cancer

  Authors:Luis Bujanda, Cristina Sarasqueta, Angel Cosme, Elizabeth Hijona, Jose M. Enriquez-Navascues, Carlos Placer, et al.From:PLoS ONE (Vol. 8, Issue 1) Peer-Reviewed

  Jan. 2, 20134,562 words Report 1470LAuthor(s): Luis Bujanda 1 , * , Cristina Sarasqueta 2 , Angel Cosme 1 , Elizabeth Hijona 1 , José M. Enríquez-Navascués 3 , Carlos Placer 3 , Eloisa Villarreal 3 , Marta Herreros-Villanueva 1 , María D. Giraldez 4 ,...

• Characterisation of the cell type-specificity of collagenase 3 mRNA expression in comparison with membrane type 1 matrix metalloproteinase and gelatinase A in the synovial membrane in rheumatoid arthritis. (Extended Report)

  Authors:PK Petrow, D Wernicke, C Schulze Westhoff, KM Hummel, R Brauer, J Kriegsmann, et al.From:Annals of the Rheumatic Diseases (Vol. 61, Issue 5) Peer-Reviewed

  May 20024,898 words Article Ann Rheum Dis 2002;61:391-397 Objective: To study the pattern and cell type-specificity of collagenase 3, membrane-type 1 matrix metalloproteinase (MT1-MMP), and gelatinase A mRNA expression in the synovial membrane...

• Carbonic Anhydrase Protects Fatty Liver Grafts against Ischemic Reperfusion Damage

  Authors:Mohamed Bejaoui, Eirini Pantazi, Viviana De Luca, Arnau Panisello, Emma Folch-Puy, Georgina Hotter, et al.From:PLoS ONE (Vol. 10, Issue 7) Peer-Reviewed

  July 30, 20157,054 words Article 1390LCarbonic anhydrases (CAs) are ubiquitous metalloenzymes that catalyze the reversible hydration of carbon dioxide to bicarbonate and a proton. CAs are involved in numerous physiological and pathological processes,...

• Suppression of MMP activity in bovine cartilage explants cultures has little if any effect on the release of aggrecanase-derived aggrecan fragments

  Authors:Bijue Wang, Pingping Chen, Anne-Christine Bay Jensen, Morten A. Karsdal, Suzi H. Madsen, Bodil-Cecilie Sondergaard, et al.From:BMC Research Notes (Vol. 2) Peer-Reviewed

  Dec. 18, 20093,743 words Report Authors: Bijue Wang [1]; Pingping Chen [1]; Anne-Christine Bay Jensen [2]; Morten A Karsdal [2]; Suzi H Madsen [2]; Bodil-Cecilie Sondergaard [2]; Qinlong Zheng [1]; Per Qvist (corresponding author) [2] Introduction...

• Characterization of phenoloxidase from the bay scallop Argopecten irradians

  Authors:Jingwei Jiang, Jing Xing, Xiuzhen Sheng, and Wenbin ZhanFrom:Journal of Shellfish Research (Vol. 30, Issue 2) Peer-Reviewed

  Aug. 20113,468 words Report 1380LABSTRACT Phenoloxidase (PO) is one of the most important factors in the bivalve immune defense system. In the current study, the PO of the scallop Argopecten irradians was purified from hemocytes using linear-gradient...

• Iron metabolism after application of modified magnetite nanoparticles in rats

  Authors:I.V. Milto, A. Yu. Grishanova, T.K. Klimenteva, I.V. Suhodolo, G. Yu. Vasukov, and V.V. IvanovaFrom:Biochemistry (Moscow) (Vol. 79, Issue 11) Peer-Reviewed

  Nov. 20145,555 words Report 1440LThe influence of modified nanosized magnetite (NSM) particles (magnetic microspheres coated with chitosan and magnetoliposomes) after a single intravenous infusion of their suspensions on iron metabolism in rats has...

• Selective Decline of Synaptic Protein Levels in the Frontal Cortex of Female Mice Deficient in the Extracellular Metalloproteinase ADAMTS1

  Authors:Matthew D. Howell, Antoni X. Torres-Collado, M. Luisa Iruela-Arispe, and Paul E. GottschallFrom:PLoS ONE (Vol. 7, Issue 10) Peer-Reviewed

  Oct. 11, 20127,677 words Report 1550LAuthor(s): Matthew D. Howell 1 , Antoni X. Torres-Collado 2 , M. Luisa Iruela-Arispe 2 , Paul E. Gottschall 1 , * Introduction The extracellular matrix (ECM) in the central nervous system (CNS) surrounds perikarya...

• Resveratrol inhibits matrix metalloproteinases to attenuate neuronal damage in cerebral ischemia: a molecular docking study exploring possible neuroprotection

  Authors:Anand Pandey, Pallab Bhattacharya, Swet Shukla, Sudip Paul, and Ranjana PatnaikFrom:Neural Regeneration Research (Vol. 10, Issue 4) Peer-Reviewed

  Apr. 20154,519 words Report 1380LByline: Anand. Pandey, Pallab. Bhattacharya, Swet. Shukla, Sudip. Paul, Ranjana. Patnaik The main pathophysiology of cerebral ischemia is the structural alteration in the neurovascular unit, coinciding with...