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    Academic Journals

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• Functions of noncoding sequences in mammalian genomes

  Authors:L.I. Patrushev and T.F. KovalenkoFrom:Biochemistry (Moscow) (Vol. 79, Issue 13) Peer-Reviewed

  Dec. 15, 201423,762 words Report 1430LMost of the mammalian genome consists of nucleotide sequences not coding for proteins. Exons of genes make up only 3% of the human genome, while the significance of most other sequences remains unknown. Recent genome...

• Uropathogenic Escherichia coli infection: potential importance of epigenetics

  Authors:Cornelia Tolg and Darius J BagliFrom:Epigenomics (Vol. 4, Issue 2) Peer-Reviewed

  Apr. 20124,572 words Report 1650LAuthor(s): Cornelia Tolg 1 , Darius J Bägli [**] 2 KEYWORDS : bladder; CDKN2A; DNA methylation; DNA methyltransferase; Helicobacter pylori; infection recurrence; Schistosoma mansoni; urinary tract infection;...

• Epigenetic biomarkers in colorectal cancer diagnostics

  Authors:James B Rawson and Bharati BapatFrom:Expert Review of Molecular Diagnostics (Vol. 12, Issue 5) Peer-Reviewed

  June 20128,729 words Report 1560LAuthor(s): James B Rawson 1 2 , Bharati Bapat [*] 3 Keywords : biomarkers; colorectal cancer; diagnosis; DNA methylation; epigenetic; miRNA; plasma; prediction; prognostication; stool Colorectal cancer (CRC)...

• Prenatal nutrition, epigenetics and schizophrenia risk: can we test causal effects?

  Authors:James B Kirkbride, Ezra Susser, Marija Kundakovic, Jacob K Kresovich, George Davey Smith, and Caroline L ReltonFrom:Epigenomics (Vol. 4, Issue 3) Peer-Reviewed

  June 20129,038 words Report 1600LAuthor(s): James B Kirkbride [*] 1 2 3 , Ezra Susser 2 3 , Marija Kundakovic 2 3 4 , Jacob K Kresovich 2 3 , George Davey Smith 5 , Caroline L Relton 6 KEYWORDS : Agouti; DNA methylation; epigenetic...

• News & Views in ... Epigenomics

  From:Epigenomics (Vol. 2, Issue 2) Peer-Reviewed

  Apr. 2010398 words Report 1510LThis finding will have an impact on our understanding of the origins of individual phenotypic differences and will have implications for future genetic studies of complex disease. The February 2010 issue of the...

• Pharmaco(epi)genomics in ovarian cancer

  Authors:Adam JW Paige and Robert BrownFrom:Pharmacogenomics (Vol. 9, Issue 12) Peer-Reviewed

  Dec. 20087,764 words Article Author(s): Adam JW Paige [[dagger]] 1 , Robert Brown 1 KEYWORDS: drug resistance; miRNA; polymorphisms; promoter methylation Ovarian cancer is the fourth most common tumor type in women in the UK, with...

• Oct4 during the pluripotency differentiation transition: who is regulating the regulator

  Authors:Lorraine E Young and Chris DenningFrom:Regenerative Medicine (Vol. 2, Issue 2)

  Mar. 20073,498 words Clinical report Author(s): Lorraine E Young [[dagger]] 1 , Chris Denning 1 Keywords: differentiation; DNA methylation; gene repression and silencing; germ cell nuclear factor; methyl-binding domain proteins; Oct4; pluripotency...

• Molecular detection of gene mutations and methylation abnormalities: applications in solid tumour diagnosis

  Authors:Alison Kraus and Marcus SchuermannFrom:Expert Review of Molecular Diagnostics (Vol. 2, Issue 2) Peer-Reviewed

  Mar. 1, 200238 words Brief article 1430LAuthor(s): Alison Kraus, Marcus Schuermann 2 Keywords: early detection; methylation; molecular screening; oncogene; PCR; PNA-clamping; tumor markers Author Affiliation(s): 2 'Klinik für Hämatologie,...

• Put the blame on methylation: this gene-silencing mechanism, not necessarily mutation, is often found culpable in creating cancerous cells. (Hot Papers)

  Author:Jim KlingFrom:The Scientist (Vol. 17, Issue 12) Peer-Reviewed

  June 16, 20031,560 words Article When good genes go bad and cancer arises, mutation normally gets the blame. But, newer evidence is challenging that one-dimensional view. Epigenetic modifications, such as DNA methylation, can also shut down tumor...

• Cancer-Type Regulation of MIG-6 Expression by Inhibitors of Methylation and Histone Deacetylation

  Authors:Yu-Wen Zhang, Ben Staal, Karl J. Dykema, Kyle A. Furge, and George F. Vande WoudeFrom:PLoS ONE (Vol. 7, Issue 6) Peer-Reviewed

  June 12, 20125,835 words Article 1530LAuthor(s): Yu-Wen Zhang 1 , * , Ben Staal 1 , Karl J. Dykema 2 , Kyle A. Furge 2 , George F. Vande Woude 1 , * Introduction Mitogen inducible gene 6 (MIG-6 ) (also known as gene 33, ERRFI1 , or RALT ) is an...

• Investigations on Transgenerational Epigenetic Response Down the Male Line in F2 Pigs

  Authors:Martin Braunschweig, Vidhya Jagannathan, Andreas Gutzwiller, and Giuseppe BeeFrom:PLoS ONE (Vol. 7, Issue 2) Peer-Reviewed

  Feb. 16, 20125,779 words Article 1480LAuthor(s): Martin Braunschweig 1 , * , Vidhya Jagannathan 1 , Andreas Gutzwiller 2 , Giuseppe Bee 2 Introduction There is a growing body of evidence that environmental effects including nutrition affect the...

• Effective DNA/RNA Co-Extraction for Analysis of MicroRNAs, mRNAs, and Genomic DNA from Formalin-Fixed Paraffin-Embedded Specimens

  Authors:Adam Kotorashvili, Andrew Ramnauth, Christina Liu, Juan Lin, Kenny Ye, Ryung Kim, et al.From:PLoS ONE (Vol. 7, Issue 4) Peer-Reviewed

  Apr. 13, 20127,334 words Clinical report 1650LAuthor(s): Adam Kotorashvili 1 , Andrew Ramnauth 1 , Christina Liu 1 , Juan Lin 1 , Kenny Ye 1 , Ryung Kim 1 , Rachel Hazan 2 , Thomas Rohan 1 , Susan Fineberg 2 , Olivier Loudig 1 , 2 , * Introduction Archived...

• Placental 11-Beta Hydroxysteroid Dehydrogenase Methylation Is Associated with Newborn Growth and a Measure of Neurobehavioral Outcome

  Authors:Carmen J. Marsit, Matthew A. Maccani, James F. Padbury, and Barry M. LesterFrom:PLoS ONE (Vol. 7, Issue 3) Peer-Reviewed

  Mar. 14, 20124,826 words Article 1680LAuthor(s): Carmen J. Marsit 1 , * , Matthew A. Maccani 2 , 3 , James F. Padbury 4 , 6 , Barry M. Lester 4 , 5 , 6 Introduction The period of intrauterine development is recognized as a critical period during which...

• Leukemia Gene Atlas - A Public Platform for Integrative Exploration of Genome-Wide Molecular Data

  Authors:Katja Hebestreit, Soren Grottrup, Daniel Emden, Jannis Veerkamp, Christian Ruckert, Hans-Ulrich Klein, et al.From:PLoS ONE (Vol. 7, Issue 6) Peer-Reviewed

  June 14, 20123,148 words Article 1370LAuthor(s): Katja Hebestreit 1 , Sören Gröttrup 1 , Daniel Emden 1 , Jannis Veerkamp 1 , Christian Ruckert 1 , Hans-Ulrich Klein 1 , Carsten Müller-Tidow 2 , Martin Dugas 1 , * Introduction Recent advances in...

• Methylomic Analysis Identifies Frequent DNA Methylation of Zinc Finger Protein 582 (ZNF582) in Cervical Neoplasms

  Authors:Rui-Lan Huang, Cheng-Chang Chang, Po-Hsuan Su, Yu-Chih Chen, Yu-Ping Liao, Hui-Chen Wang, et al.From:PLoS ONE (Vol. 7, Issue 7) Peer-Reviewed

  July 16, 20125,860 words Article 1350LAuthor(s): Rui-Lan Huang 1 , 2 , 3 , Cheng-Chang Chang 1 , 3 , 4 , Po-Hsuan Su 1 , 4 , Yu-Chih Chen 1 , 4 , Yu-Ping Liao 1 , 5 , Hui-Chen Wang 1 , 3 , Yi-Te Yo 1 , 3 , Tai-Kuang Chao 6 , Hsuan-Cheng Huang 2 , Ching-Yu...

• The CpG Island in the Murine Foxl2 Proximal Promoter Is Differentially Methylated in Primary and Immortalized Cells

  From:PLoS ONE (Vol. 8, Issue 10) Peer-Reviewed

  Oct. 2, 20138,272 words Report 1390LIntroduction Forkhead transcription factors regulate diverse biological processes including embryogenesis, cellular differentiation, cell cycle control, and immune function [1,2]. One family member, forkhead box L2 (...

• Transcriptional Suppression, DNA Methylation, and Histone Deacetylation of the Regulator of G-Protein Signaling 10 (RGS10) Gene in Ovarian Cancer Cells

  Authors:Mourad W. Ali, Ercan Cacan, Yuying Liu, Jennifer Young Pierce, William T. Creasman, Mandi M. Murph, et al.From:PLoS ONE (Vol. 8, Issue 3) Peer-Reviewed

  Mar. 22, 20138,546 words Article 1480LAuthor(s): Mourad W. Ali 1 , Ercan Cacan 2 , Yuying Liu 3 , Jennifer Young Pierce 4 , 5 , William T. Creasman 4 , 5 , Mandi M. Murph 1 , Rajgopal Govindarajan 1 , Scott T. Eblen 3 , 5 , Susanna F. Greer 2 , Shelley B....

• Chordoma Characterization of Significant Changes of the DNA Methylation Pattern

  Authors:Beate Rinner, Andreas Weinhaeusel, Birgit Lohberger, Elke Verena Froehlich, Walter Pulverer, Carina Fischer, et al.From:PLoS ONE (Vol. 8, Issue 3) Peer-Reviewed

  Mar. 22, 20134,769 words Article 1430LAuthor(s): Beate Rinner 1 , * , Andreas Weinhaeusel 2 , Birgit Lohberger 3 , Elke Verena Froehlich 3 , Walter Pulverer 2 , Carina Fischer 1 , Katharina Meditz 1 , Susanne Scheipl 3 , Slave Trajanoski 1 , Christian...

• DNA Methylation and Expression of the EgDEF1 Gene and Neighboring Retrotransposons in mantled Somaclonal Variants of Oil Palm

  Authors:Estelle Jaligot, Wei Yeng Hooi, Emilie Debladis, Frederique Richaud, Thierry Beule, Myriam Collin, et al.From:PLoS ONE (Vol. 9, Issue 3) Peer-Reviewed

  Mar. 17, 20149,823 words Article 1570LAuthor(s): Estelle Jaligot 1,*, Wei Yeng Hooi 1,4, Emilie Debladis 1, Frédérique Richaud 1, Thierry Beulé 1, Myriam Collin 2, Mawussé D. T. Agbessi 1, François Sabot 2, Olivier Garsmeur 3, Angélique D'Hont 3, Sharifah...

• Brain Region-Specific Expression of MeCP2 Isoforms Correlates with DNA Methylation within Mecp2 Regulatory Elements

  Authors:Carl O. Olson, Robby M. Zachariah, Chinelo D. Ezeonwuka, Vichithra R. B. Liyanage, and Mojgan RastegarFrom:PLoS ONE (Vol. 9, Issue 3) Peer-Reviewed

  Mar. 3, 201411,362 words Article 1440LAuthor(s): Carl O. Olson, Robby M. Zachariah, Chinelo D. Ezeonwuka, Vichithra R. B. Liyanage, Mojgan Rastegar * Introduction Mutation or altered expression of the X-linked Methyl CpG Binding Protein 2 ( MECP2 )...