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    Academic Journals

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• The birth of an alternatively spliced exon: 3' splice-site selection in Alu exons. (Reports)

  Authors:Galit Lev-Maor, Rotem Sorek, Noam Shomron, and Gil AstFrom:Science (Vol. 300, Issue 5623) Peer-Reviewed

  May 23, 20032,507 words Article Alu repetitive elements can be inserted into mature messenger RNAs via a splicing-mediated process termed exonization. To understand the molecular basis and the regulation of the process of turning intronic Alus into...

• A biologist considers a link between jumping genes and immune-system enzymes

  Author:John GreallyFrom:Nature (Vol. 456, Issue 7222) Peer-Reviewed

  Dec. 4, 2008293 words Brief article 1220LMany viruses present a fierce threat to the body. They contain nucleic acids that, when free to roam in a cell's cytoplasm, elicit an immune response involving proteins called interferons. Pairings of the nucleic-acid...

• Dissection of affinity captured LINE-1 macromolecular complexes

  Authors:Martin S Taylor, Ilya Altukhov, Kelly R Molloy, Paolo Mita, Hua Jiang, Emily M Adney, et al.From:eLife (Vol. 7) Peer-Reviewed

  Jan. 8, 201823,485 words Report 1500LLong Interspersed Nuclear Element-1 (LINE-1, L1) is a mobile genetic element active in human genomes. L1-encoded ORF1 and ORF2 proteins bind L1 RNAs, forming ribonucleoproteins (RNPs). These RNPs interact with diverse...

• Fusion of piggyBac-like transposons and herpesviruses occurs frequently in teleosts

  Authors:Yusuke Inoue, Masahiko Kumagai, Xianbo Zhang, Tomonori Saga, Deshou Wang, Akihiko Koga, et al.From:Zoological Letters (Vol. 4, Issue 1) Peer-Reviewed

  Feb. 21, 20185,659 words Report 1510LAuthor(s): Yusuke Inoue1 , Masahiko Kumagai1 , Xianbo Zhang2 , Tomonori Saga1 , Deshou Wang2 , Akihiko Koga3 and Hiroyuki Takeda1 Background Viruses are numerically the most abundant organismal entities on earth...

• NDM-1: a local clone emerges with worldwide aspirations

  Author:Andrea MarraFrom:Future Microbiology (Vol. 6, Issue 2)

  Feb. 20113,138 words Report 1340LAuthor(s): Andrea Marra 1 Keywords * antibiotic resistance; [beta]β-lactam antibiotics; ESBL; Klebsiella pneumoniae carbapenemase; MBL; mobile genetic element The antibiotic resistance determinant bla NDM-1...

• Jumping-gene roulette

  Author:Sandra L. MartinFrom:Nature (Vol. 460, Issue 7259) Peer-Reviewed

  Aug. 27, 20091,204 words Report 1540LJumping genes, which make DNA copies of themselves through an RNA middleman, provide a stochastic process for generating brain diversity among humans. The effect of their random insertion, however, is a bit of a gamble....

• Mutational signature in colorectal cancer caused by genotoxic pks.sup.+E. coli.

  Authors:Cayetano Pleguezuelos-Manzano, Jens Puschhof, Axel Rosendahl Huber, Arne van Hoeck, Henry M. Wood, Jason Nomburg, et al.From:Nature (Vol. 580, Issue 7802) Peer-Reviewed

  Apr. 20209,530 words Clinical report 1530LVarious species of the intestinal microbiota have been associated with the development of colorectal cancer.sup.1,2, but it has not been demonstrated that bacteria have a direct role in the occurrence of oncogenic...

• Exchange of functional domains between a bacterial conjugative relaxase and the integrase of the human adeno-associated virus

  Authors:Leticia Agundez, Francisco Zarate-Perez, Anita F. Meier, Martino Bardelli, Matxalen Llosa, Carlos R. Escalante, et al.From:PLoS ONE (Vol. 13, Issue 7) Peer-Reviewed

  July 17, 201812,370 words Report 1510LEndonucleases of the HUH family are specialized in processing single-stranded DNA in a variety of evolutionarily highly conserved biological processes related to mobile genetic elements. They share a structurally...

• A simple approach for multi-targeted shRNA-mediated inducible knockdowns using Sleeping Beauty vectors

  Authors:Severin Fink, Laurens Zugelder, Bernhard Roth, Evelyn Brandt, Sylvain Meloche, Zsuzsanna Izsvak, et al.From:PLoS ONE (Vol. 13, Issue 10) Peer-Reviewed

  Oct. 19, 20185,663 words Report 1640LshRNA expression is an established technique to transiently or permanently deplete cells of a particular mRNA/protein. In functional analyses of oncogenic pathways it can thus be used as an alternative to pharmacologic...

• Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis. (Reports)

  Authors:I.T. Paulsen, L. Banerjei, G.S.A. Myers, K.E. Nelson, R. Seshadri, T.D. Read, et al.From:Science (Vol. 299, Issue 5615) Peer-Reviewed

  Mar. 28, 20032,673 words Article The complete genome sequence of Enterococcus faecalis V583, a vancomycin-resistant clinical isolate, revealed that more than a quarter of the genome consists of probable mobile or foreign DNA. One of the predicted...

• Interplay of a non-conjugative integrative element and a conjugative plasmid in the spread of antibiotic resistance via suicidal plasmid transfer from an aquaculture Vibrio isolate

  Authors:Lisa Nonaka, Tatsuya Yamamoto, Fumito Maruyama, Yuu Hirose, Yuki Onishi, Takeshi Kobayashi, et al.From:PLoS ONE (Vol. 13, Issue 6) Peer-Reviewed

  June 7, 201811,999 words Report 1490LThe capture of antimicrobial resistance genes (ARGs) by mobile genetic elements (MGEs) plays a critical role in resistance acquisition for human-associated bacteria. Although aquaculture environments are recognized as...

• Degradation of antibiotic resistance genes and mobile gene elements in dairy manure anerobic digestion.

  Authors:Yi Wang, Pramod K. Pandey, Sundaram Kuppu, Richard Pereira, Sharif Aly, and Ruihong ZhangFrom:PLoS ONE (Vol. 16, Issue 8) Peer-Reviewed

  Aug. 25, 20217,858 words Report 1480LAntibiotic resistance genes (ARGs) are emerging contaminants causing serious global health concern. Interventions to address this concern include improving our understanding of methods for treating waste material of...

• An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity.

  Authors:Januka S. Athukoralage, Stephen A. McMahon, Changyi Zhang, Sabine Grüschow, Shirley Graham, Mart Krupovic, et al.From:Nature (Vol. 577, Issue 7791) Peer-Reviewed

  Jan. 23, 20209,097 words Report 1540LThe CRISPR system in bacteria and archaea provides adaptive immunity against mobile genetic elements. Type III CRISPR systems detect viral RNA, resulting in the activation of two regions of the Cas10 protein: an HD...

• Acinetobacter baumannii: an emerging multidrug-resistant threat

  Authors:Thomas D Gootz and Andrea MarraFrom:Expert Review of Anti-infective Therapy (Vol. 6, Issue 3) Peer-Reviewed

  June 200814,056 words Report Author(s): Thomas D Gootz [[dagger]] 1 , Andrea Marra 2 Keywords: antibiotic efflux; carbapenemase; cephalosporinase; insertion sequence; mobile genetic element; opportunistic infection; porin deletion...

• GeneTEFlow: A Nextflow-based pipeline for analysing gene and transposable elements expression from RNA-Seq data

  Authors:Xiaochuan Liu, Jadwiga R. Bienkowska, and Wenyan ZhongFrom:PLoS ONE (Vol. 15, Issue 8) Peer-Reviewed

  Aug. 31, 20203,262 words Report 1420LTransposable elements (TEs) are mobile genetic elements in eukaryotic genomes. Recent research highlights the important role of TEs in the embryogenesis, neurodevelopment, and immune functions. However, there is a lack...

• Of maize and men, or peas and people: case histories to justify plants and other model systems

  Author:David BaulcombeFrom:Nature Medicine (Vol. 14, Issue 10) Peer-Reviewed

  Oct. 20084,333 words Report 1300LOne of the byproducts of molecular biology has been support for the 'model system' concept. All living organisms are based on the same genetic code, they have similar subcellular structures and they use homologous...

• Emerging of antimicrobial resistance in staphylococci isolated from clinical and food samples in Algeria

  Authors:Rachid Achek, Helmut Hotzel, Zafer Cantekin, Ibrahim Nabi, Taha Mossadak Hamdi, Heinrich Neubauer, et al.From:BMC Research Notes (Vol. 11, Issue 1) Peer-Reviewed

  Sept. 12, 20183,606 words Report 1370LObjective The antimicrobial resistance of staphylococci rose worldwide. In total, 96 Staphylococcus isolates from food and clinical samples were collected from two provinces in Algeria. The antimicrobial...

• Immortalization of common marmoset monkey fibroblasts by piggyBac transposition of hTERT

  Authors:Stoyan Petkov, Tobias Kahland, Orr Shomroni, Thomas Lingner, Gabriela Salinas, Sigrid Fuchs, et al.From:PLoS ONE (Vol. 13, Issue 9) Peer-Reviewed

  Sept. 27, 20185,774 words Report 1470LFollowing a certain type-specific number of mitotic divisions, terminally differentiated cells undergo proliferative senescence, thwarting efforts to expand different cell populations in vitro for the needs of...

• Evolutionary and biogeographical implications of degraded LAGLIDADG endonuclease functionality and group I intron occurrence in stony corals (Scleractinia) and mushroom corals (Corallimorpharia)

  Authors:Juan Sebastian Celis, David R. Edgell, Bjorn Stelbrink, Daniel Wibberg, Torsten Hauffe, Jochen Blom, et al.From:PLoS ONE (Vol. 12, Issue 3) Peer-Reviewed

  Mar. 9, 20178,854 words Author abstract 1490LGroup I introns and homing endonuclease genes (HEGs) are mobile genetic elements, capable of invading target sequences in intron-less genomes. LAGLIDADG HEGs are the largest family of endonucleases, playing a key role...

• Firmicutes-enriched IS1447 represents a group of IS3-family insertion sequences exhibiting unique + 1 transcriptional slippage

  Authors:Ya-Jun Liu, Kuan Qi, Jie Zhang, Chao Chen, Qiu Cui, and Yingang FengFrom:Biotechnology for Biofuels (Vol. 11, Issue 1) Peer-Reviewed

  Nov. 1, 20188,015 words Report 1400LBackground Bacterial insertion sequences (ISs) are ubiquitous mobile genetic elements that play important roles in genome plasticity, cell adaptability, and function evolution. ISs of various families and subgroups...