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Academic Journals
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From:Expert Review of Proteomics (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Marc HV Van Regenmortel 1 The first biennial Aegean International Conference on Molecular Recognition was held in Hersonissos, Crete, Greece, on 6-11 June, 2010. The conference organizers were Heinrich...
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From:Science (Vol. 239, Issue 4842) Peer-ReviewedFirst Portrait of an Oncogene Product A research article in this issue of Science marks a new milestone in the quest to understand the action of the cancer-causing oncogenes. On page 888, Sung-Hou Kim of the...
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From:Science (Vol. 240, Issue 4852) Peer-ReviewedCrystal Structure of Tl.sub.2.Ba.sub.2.Ca.sub.2.Cu.sub.3.O.sub.10., a 125 K Superconductor MICHEL et al. REPORTED (1) superconductivity at about 20 K in the Bi/Sr/Cu/O system for a compound that we now know (2) to...
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From:Science (Vol. 258, Issue 5081) Peer-ReviewedShrink a clump of matter to a few hundred atoms, and it enters a curious netherworld. Neither ordinary solids nor conventional small molecules, such atomic clusters have unique chemical, optical, and electronic...
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From:Science (Vol. 254, Issue 5038) Peer-ReviewedThe integral membrane protein porin from Rhodobacter capsulatus consists of three tightly associated 16-stranded [Beta] barrels that give rise to three distinct diffusion channels for small solutes through the outer...
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From:Science (Vol. 254, Issue 5030) Peer-ReviewedTHE RECENTLY DEVELOPED LARGE-scale production [1, 2] and separation [3] methods for the all-carbon molecules [C.sub.60], [C.sub.70], [C.sub.76/78], [C.sub.84], and [C.sub.94] (fullerenes) have opened up new vistas in...
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From:Science (Vol. 255, Issue 5040) Peer-ReviewedAlthough tetrameric hemoglobin has been studied extensively as a prototype for understanding mechanisms of allosteric regulation, the functional and structural properties of its eight intermediate ligation forms...
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From:Science (Vol. 241, Issue 4872) Peer-ReviewedThe Structure and Symmetry of Crystalline Solid Solutions: A General Revision MIXED CRYSTALS COMPOSED OF host and guest molecules of similar molecular structures and shapes have been generally observed to exhibit the...
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From:Science (Vol. 240, Issue 4851) Peer-ReviewedEvidence from Cassette Mutagenesis for a Structure-Function Motif in a Protein of Unknown Structure ALTHOUGH FUNCTIONALLY REALATed, the members of the aminoacyl--transfer RNA (tRNA) synthetase class of enzymes are...
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From:Science (Vol. 247, Issue 4943) Peer-ReviewedQuantum Confinement and Host/Guest Chemistry: Probing a New Dimension THE EVOLUTION OF ELECTRONIC TRANSPORT MEDIA TOwards the nanosize regime has revolutionized electronic device development in terms of response times...
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From:Science (Vol. 268, Issue 5214) Peer-ReviewedA major revival in the use of classical electrostatics as an approach to the study of charged and polar molecules in aqueous solution has been made possible through the development of fast numerical and computational...
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From:Science (Vol. 271, Issue 5252) Peer-ReviewedThe Siemens Molecular Analysis Research Tool (SMART) diffractometer uses a charge-coupled device to gather hundreds of x-ray reflections of a molecule's structure. The device can analyze a new molecule in a few hours....
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From:Science (Vol. 271, Issue 5249) Peer-ReviewedThe structure of hexamethyltungsten, W[(C[H.sub.3]).sub.6], was determined by x-ray single-crystal diffraction at - 163[degrees]C. The molecule has a strongly distorted trigonal prismatic structure with [C.sub.3v]...
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From:Polymer Engineering and Science (Vol. 35, Issue 19) Peer-ReviewedThe homopolymer of maleic anhydride was synthesized by free radical initiation and characterized. Molecular mass measurements of 14 selected fractions yielded [M.sub.w] ranging from 1.1 x [10.sup.4] to 14.7 x [10.sup.4]...
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From:Nature (Vol. 468, Issue 7322) Peer-ReviewedChirality at the molecular level is found in diverse biological structures, such as polysaccharides, proteins and DNA, and is responsible for many of their unique properties (1). Introducing chirality into porous...
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From:Nature (Vol. 584, Issue 7822) Peer-ReviewedAuthor(s): David A. Leigh 1 2 , Fredrik Schaufelberger 2 , Lucian Pirvu 2 , Joakim Halldin Stenlid 3 , David P. August 2 , Julien Segard 2 Author Affiliations: (1) School of Chemistry and Molecular Engineering,...
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From:PLoS ONE (Vol. 10, Issue 11) Peer-ReviewedConformational entropy for atomic-level, three dimensional biomolecules is known experimentally to play an important role in protein-ligand discrimination, yet reliable computation of entropy remains a difficult...
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From:Biotechnology for Biofuels (Vol. 9, Issue 1) Peer-ReviewedBackground Coordination of synthesis and assembly of the polymeric components of cell walls is essential for plant growth and development. Given the degree of co-mingling and cross-linking among cell wall components,...
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From:PLoS ONE (Vol. 12, Issue 7) Peer-Reviewed
Solution conformations of Zika NS2B-NS3pro and its inhibition by natural products from edible plants
The recent Zika viral (ZIKV) epidemic has been associated with severe neurological pathologies such as neonatal microcephaly and Guillain-Barre syndrome but unfortunately no vaccine or medication is effectively... -
From:PLoS ONE (Vol. 16, Issue 7) Peer-ReviewedWe have modified the periplasmic Escherichia coli glucose/galactose binding protein (GBP) and labelled with environmentally sensitive fluorophores to further explore its potential as a sensor for the evaluation of...