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From:Indian Journal of Dermatology, Venereology, and Leprology (Vol. 75, Issue 4) Peer-ReviewedByline: Sujay. Khandpur, Saurabh. Singh, Vinod. Sharma, Ruchika. Gupta, Manoj. Singh Secondary mucin deposition in the skin is a common feature of lupus erythematosus and dermatomyositis. In scleroderma, it occurs...
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From:Biomarkers in Medicine (Vol. 1, Issue 4) Peer-ReviewedAuthor(s): Nathalie Scholler [[dagger]] 1 , Nicole Urban 2 Keywords: biomarker; CA125; detection; disease monitoring; galectin-1; glycoprotein; mesothelin; natural killer; ovarian cancer; pregnancy CA125 is one...
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From:Chest (Vol. 107, Issue 3) Peer-ReviewedTNF-[alpha]=tumor necrosis factor alpha; mRNA=messenger RNA; NO=nitric oxide; NOS=nitric oxide synthase; iNOS= calcium independent nitric oxide synthase; GPTE=guinea pig tracheal epithelial; OD=optical density; ELISA=...
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From:Indian Journal of Dermatology, Venereology, and Leprology (Vol. 80, Issue 4) Peer-ReviewedByline: Debarshi. Saha, Urmila. Khadilkar, Radha. Pai, Ashwani. Kumar Sir, Primary mucinous carcinoma of skin (PMCS), a rare malignant tumor of the sweat glands or their germinal structures was first described by...
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From:Journal of Biomedical Science (Vol. 26, Issue 1) Peer-ReviewedBackground Helicobacter pylori bacteria colonize human gastric mucosa, cause chronic inflammation, peptic ulcers and gastric cancer. Colonization is mediated by H. pylori adhesins, which preferentially bind mucin 5...
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From:PLoS ONE (Vol. 6, Issue 9) Peer-ReviewedThe sequential events and the inflammatory mediators that characterize disease onset and progression of ulcerative colitis (UC) are not well known. In this study, we evaluated the early pathologic events in the...
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From:PLoS ONE (Vol. 8, Issue 2) Peer-ReviewedHath1, a bHLH transcription factor negatively regulated by the [gamma]-secretase-dependent Notch pathway, is required for intestinal secretory cell differentiation. Our aim was fourfold: 1) determine whether Hath1 is...
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From:PLoS ONE (Vol. 10, Issue 5) Peer-ReviewedAirway mucin secretion studies have focused on goblet cell responses to exogenous agonists almost to the exclusion of baseline mucin secretion (BLMS). In human bronchial epithelial cell cultures (HBECCs), maximal...
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From:PLoS ONE (Vol. 8, Issue 6) Peer-ReviewedBackground Palmitic-acid esterified to the sn-1,3 positions of the glycerol backbone (alpha, alpha'-palmitate), the predominant palmitate conformation in regular infant formula fat, is poorly absorbed and might cause...
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From:PLoS ONE (Vol. 7, Issue 4) Peer-ReviewedOtitis media is a middle ear disease common in children under three years old. Otitis media can occur in normal individuals with no other symptoms or syndromes, but it is often seen in individuals clinically diagnosed...
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From:PLoS ONE (Vol. 10, Issue 3) Peer-ReviewedAims While overexpression of TGF[alpha] has been reported in human pancreatic ductal adenocarcinoma (PDAC), mice with overexpressed TGF[alpha] develop premalignant pancreatic acinar-to-ductal metaplasia (ADM) but not...
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From:PLoS ONE (Vol. 12, Issue 10) Peer-ReviewedThis is the first integrated study of the effects on gastric secretion, inflammation and fundic mucins after infection with L3 T. circumcincta and in the very early period following transplantation of adult worms. At 3...
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From:PLoS ONE (Vol. 9, Issue 11) Peer-ReviewedCancers exhibit abnormal molecular signatures associated with disease initiation and progression. Molecular signatures could improve cancer screening, detection, drug development and selection of appropriate drug...
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From:PLoS ONE (Vol. 9, Issue 3) Peer-ReviewedAuthor(s): Ping Liu 1, Robert Pieper 1, Juliane Rieger 2, Wilfried Vahjen 1, Roger Davin 3, Johanna Plendl 2, Wilfried Meyer 4, Jürgen Zentek 1,* Introduction For reasons of health prophylaxis and growth-promoting...
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From:PLoS ONE (Vol. 6, Issue 5) Peer-ReviewedBackground The secreted proteins from goblet cells compose the intestinal mucus. The aims of this study were to determine how they exist in two intestinal mucus layers. Methodology/Principal Findings The...
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From:PLoS ONE (Vol. 10, Issue 9) Peer-ReviewedType I interferons (IFNs) are secreted by many cell types upon stimulation via pattern recognition receptors and bind to IFN-[alpha]/[beta] receptor (IFNAR), which is composed of IFNAR1 and IFNAR2. Although type I IFNs...
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From:Journal of Ophthalmology (Vol. 2018) Peer-ReviewedBackground. Vernal keratoconjunctivitis (VKC) is a rare ocular surface inflammatory disease that affects mainly boys in the first decade of life. Clinical observations show that it generally regresses spontaneously with...
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From:Journal of Clinical Investigation (Vol. 129, Issue 10) Peer-ReviewedCystic fibrosis (CF) lung disease is characterized by early and persistent mucus accumulation and neutrophilic inflammation in the distal airways. Identification of the factors in CF mucopurulent secretions that...
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From:PLoS ONE (Vol. 12, Issue 12) Peer-ReviewedThe aim of this study was to identify potential mucin genes in the Atlantic salmon genome and evaluate tissue-specific distribution and transcriptional regulation in response to aquaculture-relevant stress conditions in...
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From:Stem Cell Research & Therapy (Vol. 6, Issue 1) Peer-ReviewedIntroduction Allogenic dendritic cells (DCs) generated from healthy donors, who are complete or partially HLA-matched, have been used for clinical trials. One of the sources for allogenic DCs is umbilical cord blood...