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    Academic Journals

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• Does early enteral feeding of very low birth weight infants increase the risk of necrotizing enterocolitis?

  Authors:F. Cakmak Celik, C. Aygun, and E. CetinogluFrom:European Journal of Clinical Nutrition (Vol. 63, Issue 4) Peer-Reviewed

  Apr. 20093,225 words Report Background/Objective: In this retrospective study, we intended to test whether early enteral feeding (EEF) of very low birth weight (VLBW) preterm babies increases the risk of necrotizing enterocolitis (NEC) or not....

• Serologic intestinal-fatty acid binding protein in necrotizing enterocolitis diagnosis: a meta-analysis

  Authors:Shupeng Cheng, Jialin Yu, Min Zhou, Yan Tu, and Qi LuFrom:BioMed Research InternationalPeer-Reviewed

  Annual 20153,409 words Report 1360LBackground. Previous studies showed that intestinal-fatty acid binding protein (I-FABP) may be a valid and promising serologic biomarker for early diagnosis of necrotizing enterocolitis (NEC). Objective. To investigate...

• Magnetic Resonance Imaging of Intestinal Necrosis in Preterm Infants

  Authors:Elia F. Maalouf, Andrew Fagbemi, Philip J. Duggan, Subramanyam Jayanthi, Serena J. Counsell, Helen J. Lewis, et al.From:Pediatrics (Vol. 105, Issue 3) Peer-Reviewed

  Mar. 20003,103 words Article Background and Objective. Noninvasive diagnosis of intestinal necrosis is important in planning surgery in preterm infants with necrotizing enterocolitis (NEC). We aimed to assess the potential of magnetic resonance...

• Necrotizing Enterocolitis (NEC) and the Risk of Intestinal Stricture: The Value of C-Reactive Protein

  Authors:Aurelie Gaudin, Caroline Farnoux, Arnaud Bonnard, Marianne Alison, Laure Maury, Valerie Biran, et al.From:PLoS ONE (Vol. 8, Issue 10) Peer-Reviewed

  Oct. 11, 20135,548 words Article 1390LNecrotizing enterocolitis (NEC) is a severe complication frequently seen during the neonatal period associated with high mortality rate and severe and prolonged morbidity including Post-NEC intestinal stricture. The aim...

• The association of severe anemia, red blood cell transfusion and necrotizing enterocolitis in neonates.

  Authors:Juan Song, Huimin Dong, Falin Xu, Yong Wang, Wendong Li, Zhenzhen Jue, et al.From:PLoS ONE (Vol. 16, Issue 7) Peer-Reviewed

  July 20, 20214,468 words Report 1460LBackground The relationship between severe anemia, red blood cell transfusion and Neonatal necrotizing enterocolitis (NEC) remains controversial. The purpose of this study was to determine the association of severe...

• Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis

  Authors:Shiloh R. Lueschow, Jessica Stumphy, Huiyu Gong, Stacy L. Kern, Timothy G. Elgin, Mark A. Underwood, et al.From:PLoS ONE (Vol. 13, Issue 10) Peer-Reviewed

  Oct. 1, 20188,121 words Report 1540LNecrotizing enterocolitis (NEC) remains the leading cause of gastrointestinal morbidity and mortality in premature infants. Human and animal studies suggest a role for Paneth cells in NEC pathogenesis. Paneth cells play...

• Necrotizing Enterocolitis in Moderate Preterm Infants.

  Authors:Jayasree Nair, Rachel Longendyke, and Satyan LakshminrusimhaFrom:BioMed Research International (Vol. 2018) Peer-Reviewed

  Annual 20183,620 words Article 1400LNecrotizing enterocolitis (NEC) is a devastating morbidity usually seen in preterm infants, with extremely preterm neonates (EPT [less than or equal to]28 weeks) considered at highest risk. Moderately preterm infants...

• The role of hypoxia and endotoxin in a piglet model of advanced necrotising enterocolitis (NEC)

  Authors:A.S. Dhillon, W. Al-Salti, J.M. Marshall, A.D Lander, I.W. Booth, and A.K. EwerFrom:Archives of Disease in Childhood (Vol. 89, Issue 4) Peer-Reviewed

  Apr. 2004387 words Article Background: Hypoxia and bacterial colonisation are major risk factors for NEC. Aim: To investigate the role of hypoxia and endotoxin (lipopoly-saccharide, LPS), both singly and in combination, on the degree of...

• A meta-analysis of probiotics for preventing necrotizing enterocolitis in preterm neonates

  Authors:Y. Yang, Y. Guo, Q. Kan, X.G. Zhou, X.Y. Zhou, and Y. LiFrom:Brazilian Journal of Medical and Biological Research (Vol. 47, Issue 9) Peer-Reviewed

  Sept. 20144,778 words Report 1380LNecrotizing enterocolitis (NEC) is one of the most common acquired diseases of the gastrointestinal tract in preterm infants. Some randomized, controlled trials (RCTs) have indicated that probiotics may potentially...

• Necrotizing enterocolitis in adults: a study of four cases

  Authors:Avinash N. Katara, Vinod A. Chandiramani, Rajeev Soman, Anita Bhaduri, and Devendra C. DesaiFrom:Indian Journal of Surgery (Vol. 66, Issue 2) Peer-Reviewed

  March-April 20042,003 words Article ABSTRACT Necrotizing enterocolitis is an acute disease that primarily affects premature neonates of low birth weight, and has a very high morbidity and mortality. The incidence in adults is significantly less, with...

• Effects of oropharyngeal administration of colostrum on the incidence of necrotizing enterocolitis, late-onset sepsis, and death in preterm infants: a meta-analysis of RCTs.

  Authors:Jiaxin Tao, Jing Mao, Jixin Yang, and Yanwei SuFrom:European Journal of Clinical Nutrition (Vol. 74, Issue 8) Peer-Reviewed

  Aug. 20206,472 words Article 1410LNecrotizing enterocolitis (NEC) and late-onset sepsis (LOS) are two major contributors to death among preterm infants. Oropharyngeal administration of colostrum (OAC) has been proved as an easy, safe, and economically...

• Fecal Bile Salts and the Development of Necrotizing Enterocolitis in Preterm Infants

  Authors:Christian V. Hulzebos, Anne G. J. F. van Zoonen, Jan B. F. Hulscher, Trijntje E. Schat, Elisabeth M. W. Kooi, Martijn Koehorst, et al.From:PLoS ONE (Vol. 12, Issue 1) Peer-Reviewed

  Jan. 3, 20175,000 words Report 1450LBackground Intestinal bile salts (BSs) may be implicated in NEC development. We hypothesized that fecal BS levels are higher in preterm infants at risk for NEC. Methods We compared the composition and...

• Bovine milk-derived exosomes enhance goblet cell activity and prevent the development of experimental necrotizing enterocolitis

  Authors:Bo Li, Alison Hock, Richard Y. Wu, Adam Minich, Steven R. Botts, Carol Lee, et al.From:PLoS ONE (Vol. 14, Issue 1) Peer-Reviewed

  Jan. 30, 20195,227 words Report 1470LNecrotizing enterocolitis (NEC) is characterized by intestinal injury and impaired mucin synthesis. We recently showed that breast milk exosomes from rodents promote intestinal cell viability, epithelial proliferation,...

• Use of cholecystokinin-octapeptide for the prevention of parenteral nutrition-associated cholestasis

  Authors:Daniel H. Teitelbaum, Thomas F. Tracy, Jr., Moustafa M. Aouthmany, Adolfo Llanos, Morton B. Brown, Sunkyung Yu, et al.From:Pediatrics (Vol. 115, Issue 5) Peer-Reviewed

  May 20057,001 words Article Objective. To determine whether cholecystokinin-octapeptide (CCK-OP) would prevent or ameliorate parenteral nutrition-associated cholestasis (PNAC) among high-risk neonates treated with total parenteral nutrition....

• Commensal Propionibacterium strain UF1 mitigates intestinal inflammation via Th17 cell regulation

  Authors:Natacha Colliou, Yong Ge, Bikash Sahay, Minghao Gong, Mojgan Zadeh, Jennifer L. Owen, et al.From:Journal of Clinical Investigation (Vol. 127, Issue 11) Peer-Reviewed

  Nov. 201711,235 words Article 1550LConsumption of human breast milk (HBM) attenuates the incidence of necrotizing enterocolitis (NEC), which remains a leading and intractable cause of mortality in preterm infants. Here, we report that this diminution...

• Lysozyme and secretory phospholipase A2 expression in necrotizing enterocolitis

  Authors:S. Lala, D. Turton, and S. KeshavFrom:Gut (Vol. 53, Issue 4) Peer-Reviewed

  Apr. 2004389 words Article Introduction: Necrotising enterocolitis (NEC) is a severe inflammatory gastrointestinal disorder predominantly affecting neonates. A leading theory postulates that NEC develops when aberrant colonisation by enteric...

• Primary peritoneal drainage in neonates with necrotizing enterocolitis associated with congenital heart disease: a single experience in a Brazilian tertiary center.

  Authors:W.C. Canesin, F.A.P. Volpe, W.A. Goncalves-Ferri, P.H. Manso, D.C. Aragon, and L. SbragiaFrom:Brazilian Journal of Medical and Biological Research (Vol. 54, Issue 9) Peer-Reviewed

  Sept. 20213,050 words Article 1390LNecrotizing enterocolitis (NEC) is a common condition in preterm infants. The risk factors that contribute to NEC include asphyxia, apnea, hypotension, sepsis, and congenital heart diseases (CHD). The objective of this...

• The surgical management of necrotising enterocolitis

  Author:Agostino PierroFrom:Early Human Development (Vol. 81, Issue 1) Peer-Reviewed

  Jan. 20054,563 words Article Abstract Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in neonates. The disease affects mainly premature neonates. The pathogenesis is still unknown but predisposing factors are...

• Empirical antibiotic treatment and the risk of necrotizing enterocolitis and death in very low birth weight neonates. (original article)

  Authors:Eman A. Abdel Ghany and Aliaa A. AliFrom:Annals of Saudi Medicine (Vol. 32, Issue 5) Peer-Reviewed

  September-October 20123,498 words Article 1810LBACKGROUND AND OBJECTIVES: Antibiotics are one of the most overused drugs in the neonatal unit. Our objective was to assess associations between the duration of the initial antibiotic course and subsequent necrotizing...

• NEC-zero recommendations from scoping review of evidence to prevent and foster timely recognition of necrotizing enterocolitis

  Authors:Sheila M. Gephart, Corrine Hanson, Christine M. Wetzel, Michelle Fleiner, Erin Umberger, Laura Martin, et al.From:Maternal Health, Neonatology and Perinatology (Vol. 3, Issue 1) Peer-Reviewed

  Dec. 18, 20178,199 words Report 1490LBackground Although decades have focused on unraveling its etiology, necrotizing enterocolitis (NEC) remains a chief threat to the health of premature infants. Both modifiable and non-modifiable risk factors...