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• Immunomodulatory activity of methanolic extracts of fruits and bark of Ficus glomerata Roxb. in mice and on human neutrophils

  Authors:Sanjeev Heroor, Arun Beknal, and Nitin MahurkarFrom:Indian Journal of Pharmacology (Vol. 45, Issue 2) Peer-Reviewed

  March-April 20133,451 words Report 1600LByline: Sanjeev. Heroor, Arun. Beknal, Nitin. Mahurkar Objective: To evaluate the immunomodulatory activity of methanolic extracts of fruit and bark of Ficus glomerata Roxb. on cyclophosphamide-induced...

• Neutrophils in tuberculosis: will code be unlocked?

  Authors:K. Karthik, M. Kesavan, P. Tamilmahan, M. Saravanan, and M. DashprakashFrom:Veterinary World (Vol. 6, Issue 2)

  Feb. 20132,495 words Report 1100LTuberculosis is a devastating disease throughout the world both in humans and animals. Its history is vast, which dates back to era of Robert Koch. There is a huge amount of immunological studies in the aspect of...

• Urinary neutrophil gelatinase-associated lipocalin in critically ill surgical cancer patients

  Authors:Pericles Delfino Duarte, Andreia Fumagalli, Vanessa Wandeur, and Delmiro BeckerFrom:Indian Journal of Critical Care Medicine (Vol. 19, Issue 5) Peer-Reviewed

  May 20152,868 words Report 1790LByline: Pericles. Delfino Duarte, Andreia. Fumagalli, Vanessa. Wandeur, Delmiro. Becker Background and Aims: Neutrophil gelatinase-associated lipocalin (N-GAL) is an early biomarker of acute kidney injury (AKI) due...

• Neutrophil Immunodeficiency

  From:Science (Vol. 288, Issue 5468) Peer-Reviewed

  May 12, 2000160 words Brief article Neutrophils migrate to and engulf foreign pathogens and then kill them by means of an onslaught of degradative enzymes and toxic oxygen metabolites, such as superoxide. Ambruso et al. report the identification of a...

• Regulation of proteolysis at the neutrophil-substrate interface by secretory leukoprotease inhibitor

  Authors:William G. Rice and Stephen J. WeissFrom:Science (Vol. 249, Issue 4965) Peer-Reviewed

  July 13, 19903,290 words Article Neutrophils are a class of white blood cells, or leukocytes, which are capable of destroying tissues using powerful proteases, or enzymes which break down proteins. Although blood plasma contains many substances which...

• Two forms of autosomal chronic granulomatous disease lack distinct neutrophil cytosol factors

  Authors:Hiroyuki Nunoi, Daniel Rotrosen, John I. Gallin, and Harry L. MalechFrom:Science (Vol. 242, Issue 4883) Peer-Reviewed

  Dec. 2, 19881,861 words Article Two Forms of Autosonal Chronic Granulomatous Disease Lack Distinct Neutrophil Cytosol Factors CHRONIC GRANULOMATOUS DISEASES of childhood (CGD) are a genetically heterogeneous group of disorders of phagocytic cell...

• Anti-inflammatory action of erythromycin: its inhibitory effect on neutrophil NADPH oxidase activity

  Author:Shigenobu UmekiFrom:Chest (Vol. 104, Issue 4) Peer-Reviewed

  Oct. 19931,609 words Article The effects of erythromycin on the NADPH oxidase activity in the neutrophils of normal subjects and patients with bronchiolitis were investigated. In the patients receiving erythromycin, NADPH oxidase activity was...

• Association between neutrophil concentration in bronchoalveolar lavage fluid and recent losses in diffusing capacity in men formerly exposed to asbestos

  Authors:Mark R. Cullen and William W. MerrillFrom:Chest (Vol. 102, Issue 3) Peer-Reviewed

  Sept. 19924,813 words Article It has been observed widely that some individuals exposed to asbestos will experience continued losses of lung function after asbestos exposure ceases. Unfortunately, there are few data on factors that determine...

• Dynamic changes of plasma neutrophil gelatinase-associated lipocalin predicted mortality in critically ill patients with systemic inflammatory response syndrome

  Authors:Azrina Ralib, Suhaila Nanyan, and Mohd Mat NorFrom:Indian Journal of Critical Care Medicine (Vol. 21, Issue 1) Peer-Reviewed

  Jan. 20173,392 words Clinical report 1500LByline: Azrina. Ralib, Suhaila. Nanyan, Mohd. Mat Nor Background and Aims: About 50% of patients admitted to the Intensive Care Unit have systemic inflammatory response syndrome (SIRS), and about 10%-20% of them...

• The effect of furosemide on the level of neutrophil gelatinase-associated lipocalin in critically hospitalized patients with acute kidney injury

  Authors:Hadi Hamishehkar, Sarvin Sanaie, Vahid Fattahi, Mehran Mesgari, and Ata MahmoodpoorFrom:Indian Journal of Critical Care Medicine (Vol. 21, Issue 7) Peer-Reviewed

  July 20173,650 words Report 1610LByline: Hadi. Hamishehkar, Sarvin. Sanaie, Vahid. Fattahi, Mehran. Mesgari, Ata. Mahmoodpoor Background and Aims: Oliguric acute kidney injury (AKI), commonly attributed to a more severe degree of renal injury, is...

• Evaluation of neutrophil gelatinase-associated lipocalin and cystatin C as early markers of diabetic nephropathy

  Authors:Zeba Siddiqi, Ritu Karoli, Anupama Kaul, Jalees Fatima, Shishir Varshney, and Mohd BegFrom:Annals of African Medicine (Vol. 16, Issue 3) Peer-Reviewed

  July-September 20173,116 words Report 1850LByline: Zeba. Siddiqi, Ritu. Karoli, Anupama. Kaul, Jalees. Fatima, Shishir. Varshney, Mohd. Beg Introduction: Diabetes mellitus (DM) is a major cause of concern because of its increasing prevalence rate and related...

• The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice

  Authors:Hitesh S. Deshmukh, Yuhong Liu, Ogechukwu R. Menkiti, Junjie Mei, Ning Dai, Claire E. O'Leary, et al.From:Nature Medicine (Vol. 20, Issue 5) Peer-Reviewed

  May 20145,826 words Letter to the editor 1630LNeonatal colonization by microbes, which begins immediately after birth, is influenced by gestational age and the mother's microbiota and is modified by exposure to antibiotics (1). In neonates, prolonged duration of...

• Effect of granulocyte-colony stimulating factor on generation of oxygen-derived free radicals and myeloperoxidase activity in neutrophils from poorly controlled NIDDM patients

  Authors:Noriyuki Sato, Koji Kashima, Yoshito Tanaka, Hiroyuki Shimizu, and Masatomo MoriFrom:Diabetes (Vol. 46, Issue 1) Peer-Reviewed

  Jan. 19973,017 words Article To evaluate whether granulocyte-colony stimulating factor (G-CSF) improves an impaired production of oxygen-derived free radicals by neutrophils from poorly controlled NIDDM patients, we studied the effect of G-CSF on...

• Netting neutrophils in autoimmune small-vessel vasculitis

  Authors:Kai Kessenbrock, Markus Krumbholz, Ulf Schonermarck, Walter Back, Wolfgang L. Gross, Zena Werb, et al.From:Nature Medicine (Vol. 15, Issue 6) Peer-Reviewed

  June 20091,794 words Report Small-vessel vasculitis (SVV) is a chronic autoinflammatory condition linked to antineutrophil cytoplasm autoantibodies (ANCAs). Here we show that chromatin fibers, so-called neutrophil extracellular traps (NETs), are...

• Howell-Jolly Body-Like Inclusions in Neutrophils of Patients With Myelodysplastic Syndrome: A Novel Correlation

  Authors:Yi Tat Tong, Nghia D. Nguyen, and Amer WahedFrom:Archives of Pathology & Laboratory Medicine (Vol. 143, Issue 1) Peer-Reviewed

  Jan. 20191,191 words Report 1390L* Context.--Howell-Jolly body-like inclusions have been previously associated with patients who are human immunodeficiency virus (HIV) infected, taking antiviral medications, and immunosuppressed. These inclusions...

• Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: a randomized, double-blind, placebo-controlled trial

  Authors:E. Dalli, E. Colomer, M.C. Tormos, J. Cosin-Sales, J. Milara, E. Esteban, et al.From:Phytomedicine: International Journal of Phytotherapy & Phytopharmacology (Vol. 18, Issue 8-9) Peer-Reviewed

  June 15, 20114,945 words Report 1420LARTICLE INFO Keywords: Crataegus laevigata (Rosaceae) Neutrophil function Elastase Coronary heart disease Randomized, double blind placebo controlled trial ABSTRACT Crataegus laevigata is a...

• How NETs form to capture invaders

  From:Nature (Vol. 468, Issue 7320) Peer-Reviewed

  Nov. 4, 2010129 words Brief article 1390LAs a first line of defence against microbes, immune cells called neutrophils release webs of uncoiled DNA strands and antimicrobial molecules to ensnare and kill the invaders (pictured). Researchers have identified two...

• Fragile neutrophils in surgical patients: A phenomenon associated with critical illness

  Authors:Lillian Hesselink, Roy Spijkerman, Pien Hellebrekers, Robert J. van Bourgondien, Enja Blasse, Saskia Haitjema, et al.From:PLoS ONE (Vol. 15, Issue 8) Peer-Reviewed

  Aug. 4, 20208,224 words Report 1430LAuthor(s): Lillian Hesselink 1,2,*, Roy Spijkerman 1,2, Pien Hellebrekers 1,2, Robert J. van Bourgondiën 1, Enja Blasse 3, Saskia Haitjema 3, Albert Huisman 3, Wouter W. van Solinge 3, Karlijn J. P. Van Wessem 1, Leo...

• Wegener's granulomatosis presenting as acute respiratory failure with anti-neutrophil-cytoplasm antibodies

  Authors:Christine Lenclud, Paul De Vuyst, Etienne Dupont, Michel Deprierreux, Paulette Ketelbant, and Michel GoldmanFrom:Chest (Vol. 96, Issue 2) Peer-Reviewed

  Aug. 19891,916 words Article Christine Lenclud, M.D.;(*1) Paul De Vuyst, M.D.;(*1) Etienne Dupont, M.D.;([unkeyable]) Michel Depierreux, M.D.;([unkeyable]) Paulette Ketelbant, M.D.;([unkeyable]) Michel Goldman, M.D.; Section...

• Functional [alpha].sub.4-integrin: A newly identified pathway of neutrophil recruitment in critically ill septic patients

  Authors:Geoffrey C. Ibbotson, Christopher Doig, Jaswinder Kaur, Varinder Gill, Lena Ostrovsky, Todd Fairhead, et al.From:Nature Medicine (Vol. 7, Issue 4) Peer-Reviewed

  Apr. 20015,416 words Report 1390LUsing a novel flow chamber assay system and whole blood, we show that leukocytes from septic individuals have a four-fold elevation of adhesion, but not rolling, on a P-selectin/[beta].sub.2-integrin substrate. Most...