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Academic Journals
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From:Reactions Weekly (Issue 1301)[S] A 42-year-old woman developed osteonecrosis after receiving methylprednisolone. The woman had received three 5-day courses of oral methylprednisolone 500 mg/day since October 2007 for the symptomatic treatment...
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From:Reactions Weekly (Issue 1317)[S] A woman developed osteonecrosis of the jaw (ONJ) following treatment with clodronic acid [therapeutic indication not stated]. In 1987, the woman underwent surgery for breast cancer, at age 58 years. Bone...
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From:Reactions Weekly (Issue 1274)[S] A woman developed osteonecrosis of the jaw (ONJ) associated with the use of etidronic acid, clodronic acid, pamidronic acid and zoledronic acid [dosages and durations of therapies to reaction onsets not stated]....
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From:The Journal of Musculoskeletal Medicine (Vol. 24, Issue 4) Peer-ReviewedByline: DAVID PUGLIESE, DO, THOMAS OLENGINSKI, MD ABSTRACT: Osteoporosis, the most common metabolic bone disease, has significant physical and emotional sequelae. Complicating identification of the disease is its...
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From:BioMed Research International (Vol. 2017) Peer-ReviewedSteroid-associated osteonecrosis of the femoral head remains a challenging problem in orthopedics worldwide. One pathomechanism is ischemia of the femoral head, as a result of thrombus formation and vasoconstriction....
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From:BioMed Research International (Vol. 2017) Peer-ReviewedObjective. The present study aimed to investigate the role of periapical diseases in inducing medication-related osteonecrosis of the jaws (MRONJ) using an ovariectomized (OVX) mice model. Materials and Methods. Twenty...
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From:PLoS ONE (Vol. 13, Issue 11) Peer-ReviewedOur objective was to investigate direct voxel-wise relationship between dose and early MR biomarker changes both within and in the high-dose region surrounding brain metastases following stereotactic radiosurgery (SRS)....
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From:PLoS ONE (Vol. 9, Issue 6) Peer-ReviewedThe purpose of this study was to compare the clinical outcomes of impacted bone graft with or without recombinant human bone morphogenetic protein-2 (rhBMP-2) for osteonecrosis of the femoral head (ONFH). We examined...
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From:Journal of Research in Medical Sciences (Vol. 22, Issue 1) Peer-ReviewedByline: Feng. Liu, Wei. Wang, Lei. Yang, Benjie. Wang, Jianchuan. Wang, Weifang. Chai, Dewei. Zhao Background: Osteonecrosis of the femoral head (ONFH) is a common disease with high disability rate. However, a few...
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From:Reactions Weekly (Issue 1250)Three men developed jaw osteonecrosis during treatment with zoledronic acid. Treatment included curettage in one patient and conservative management in other patients [outcome not clearly stated]. A 60-year-old man,...
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From:Reactions Weekly (Issue 1328)[S] Two women with multiple myeloma and two men with prostate cancer bone metastases, aged 65-72 years, developed osteonecrosis of the jaw during treatment with IV zoledronic acid (zoledronate). The patients were...
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From:Reactions Weekly (Issue 1329)[S] Three patients developed jaw osteonecrosis during chemotherapy with pamidronic acid and/or zoledronic acid [dosages not stated; routes not stated in all cases]. A 53-year-old man was diagnosed with stage IV...
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From:BioMed Research InternationalPeer-ReviewedThe purpose of the current review was to determine the efficacy of alendronate for preventing collapse of femoral head in adult patients with nontraumatic avascular osteonecrosis of femoral head (ANFH). Five randomized...
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From:Reactions Weekly (Issue 1332)[S] A 38-year-old woman developed bilateral, bicondylar femoral osteonecrosis during treatment with methylprednisolone for Behcet's disease. Seven months prior, the woman had been diagnosed with Behget's disease...
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From:Reactions Weekly (Issue 1264)[S] A 71-year-old woman developed osteonecrosis of the jaw while receiving oral alendronic acid. The woman presented with a swelling on the lower-right facial area. She had osteoporosis and had been receiving...
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From:BioMed Research InternationalPeer-ReviewedSex determining region Y-box 9 (SOX9) is a key transcription factor involved in cartilage formation during the embryonic development stage and cartilage growth and repair after birth. To explore the roles of...
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From:AAOS NowPeer-ReviewedKnee osteonecrosis (ON) is a progressive disease that can lead to subchondral collapse and debilitating arthritis. Researchers initially thought it developed spontaneously and typically involved the medial femoral...
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From:PLoS ONE (Vol. 10, Issue 7) Peer-ReviewedValidation of claims-based algorithms to identify serious hypersensitivity reactions and osteonecrosis of the jaw has not been performed in large osteoporosis populations. The objective of this project is to estimate...
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From:PLoS ONE (Vol. 14, Issue 2) Peer-ReviewedOsteonecrosis of the jaw induced by administration of bisphosphonates (BPs), BP-related osteonecrosis (BRONJ), typically develops after tooth extraction and is medically challenging. As BPs inhibit oral mucosal cell...
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From:PLoS ONE (Vol. 13, Issue 12) Peer-ReviewedDespite good clinical outcomes associated with curved intertrochanteric varus osteotomy for the treatment of osteonecrosis of the femoral head, post-operative leg-length discrepancy is frequently reported and might...