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• Serotonin syndrome and death, possibly caused by moclobemide, sertraline and pimozide interaction. (Drug-Drug Interactions)

  Author:Y.W. Francis LamFrom:The Brown University Psychopharmacology Update (Vol. 14, Issue 5)

  May 2003 Article

• Pimozide Suppresses the Growth of Brain Tumors by Targeting STAT3-Mediated Autophagy.

  Authors:Alok Ranjan, Itishree Kaushik, and Sanjay K. SrivastavaFrom:Cells (Vol. 9, Issue 9) Peer-Reviewed

  Sept. 20206,963 words Report 1400LBrain tumors are considered as one of the most aggressive and incurable forms of cancer. The majority of the patients with brain tumors have a median survival rate of 12%. Brain tumors are lethal despite the availability...

• The enhanced antitumour response of pimozide combined with the IDO inhibitor L-MT in melanoma

  Authors:Huijie Jia, Wenjing Ren, Yuchen Feng, Tian Wei, Mengmeng Guo, Jing Guo, et al.From:International Journal of Oncology (Vol. 53, Issue 3) Peer-Reviewed

  Sept. 20186,422 words Report 1380LMelanoma is one of the most fatal and therapy resistant types of cancer; therefore, identifying novel therapeutic candidates to improve patient survival is an ongoing effort. Previous studies have revealed that pimozide...

• Studies from V. Fako et al in the Area of Hepatocellular Carcinoma Described (Inhibition of wnt/beta-catenin Signaling in Hepatocellular Carcinoma by an Antipsychotic Drug Pimozide)

  From:Obesity, Fitness & Wellness Week

  June 25, 2016356 words Brief article, Repor... 1490L2016 JUN 25 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on Digestive System Diseases and Conditions are discussed in a new report. According to news...

• Pimozide: An old wine in a new bottle!

  Author:Ahmed NaguyFrom:Indian Journal of Psychological Medicine (Vol. 39, Issue 3)

  May-June 2017970 words Letter to the editor 1490LByline: Ahmed. Naguy Sir, Pimozide is a high-potency conventional antipsychotic drug of the diphenylbutylpiperidine group (2 mg ≈ 2–3 mg haloperidol). It selectively blocks D1–D2 receptors and...

• Findings from Department of Biochemistry Provide New Insights into Cancer Therapy (Pimozide suppresses colorectal cancer via inhibition of Wnt/beta-catenin signaling pathway)

  From:Obesity, Fitness & Wellness Week

  Oct. 6, 2018508 words Report 1490L2018 OCT 6 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on Drugs and Therapies - Cancer Therapy are discussed in a new report. According to news reporting...

• Pimozide augmentation therapy in treatment-resistant schizophrenia patients with poor or partial response to clozapine: a retrospective study/Klozapin tedavisine yeterli yanit alinamayan tedaviye direncli sizofreni hastalarinda pimozidle guclendirme yaklasimi: geriye donuk bir degerlendirme calismasi

  Authors:Cebrail Kisa, Hatice Alkan Akdag, Cigdem Aydemir, and Erol GokaFrom:Archives of Neuropsychiatry (Vol. 47, Issue 4) Peer-Reviewed

  Dec. 20104,104 words Report 1480LObjective: In this retrospective chart review study we aimed to investigate the effect of pimozide augmentation on schizophrenia patients with poor or partial response to clozapine therapy. Methods: Charts of 17...

• Memory enhancing effects of nicotine, cocaine, and their conditioned stimuli; effects of beta-adrenergic and dopamine D2 receptor antagonists.

  Authors:Michael Wolter, Thomas Lapointe, Brett Melanson, Nana Baidoo, Travis Francis, Boyer D. Winters, et al.From:Psychopharmacology (Vol. 238, Issue 9) Peer-Reviewed

  Sept. 20218,175 words Report 1630LBackground There is evidence that post-training exposure to nicotine, cocaine, and their conditioned stimuli (CS), enhance memory consolidation in rats. The present study assessed the effects of blocking noradrenergic...

• Findings on Carbon Nanotubes Reported by Investigators at Ankara University (Nh2-functionalized Multi Walled Carbon Nanotubes Decorated With Zno Nanoparticles and Graphene Quantum Dots for Sensitive Assay of Pimozide)

  From:Obesity, Fitness & Wellness Week

  Aug. 3, 2019441 words Report 1470L2019 AUG 3 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on Nanotechnology - Carbon Nanotubes have been published. According to news reporting originating...

• Pimozide Warning

  Author:Mike BykowskiFrom:OB GYN News (Vol. 34, Issue 22)

  Nov. 15, 1999199 words Brief article The manufacturer of pimozide has issued a warning about sudden unexpected deaths in patients on high doses of the antipsychotic and has issued a new contraindication for the drug. Pimozide is approved to treat tics...

• Research Results from Texas Tech University Health Sciences Center Update Knowledge of Brain Cancer (Pimozide Suppresses the Growth of Brain Tumors by Targeting STAT3-Mediated Autophagy).

  From:Obesity, Fitness & Wellness Week

  Oct. 10, 2020493 words Article 1350L2020 OCT 10 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New study results on brain cancer have been published. According to news reporting originating from Texas Tech...

• Pimozide augments bromocriptine lethality in prolactinoma cells and in a xenograft model via the STAT5/cyclin D1 and STAT5/Bcl-xL signaling pathways.

  Authors:Zhengzheng Xiao, Jing Liang, Qing Deng, Chaojun Song, Xiaoli Yang, Zebin Liu, et al.From:International Journal of Molecular Medicine (Vol. 47, Issue 1) Peer-Reviewed

  Jan. 20217,003 words Article 1330LAs hyperprolactinemia is observed in patients with bromocriptine-resistant prolactinoma, prolactin (PRL) has been implicated in the development of bromocriptine resistance. Since PRL primarily mediates cell survival and...

• Pimozide: psychomotor agitation: case report

  From:Reactions Weekly (Issue 1284)

  Jan. 16, 2010147 words Brief article, Case ... 840LA 29-year-old pregnant woman started receiving pimozide 4 mg/day during her fifth gestational month for vocal and motor tics associated with Gilles de la Tourette's syndrome. Within 1 week of birth, she developed...

• Don't mix Zoloft with pimozide, Pfizer warns. (Possible Interaction)

  Author:Deeanna FranklinFrom:Internal Medicine News (Vol. 36, Issue 2)

  Jan. 15, 2003340 words Brief article At the request of the U.S. Food and Drug Administration, Pfizer has issued a warning on possible interaction between its drug sertraline (Zoloft) and the antipsychotic drug pimozide (Orap). Pimozide is indicated for...

• New Alzheimer Disease Study Results Reported from Seoul National University (Pimozide reduces toxic forms of tau in TauC3 mice via 5' adenosine monophosphate-activated protein kinase-mediated autophagy)

  From:Obesity, Fitness & Wellness Week

  July 29, 2017463 words Report 1450L2017 JUL 29 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Fresh data on Neurodegenerative Diseases and Conditions - Alzheimer Disease are presented in a new report. According to...

• Olfactory Reference Syndrome with Suicidal Attempt Treated with Pimozide and Fluvoxamine

  Authors:Oluwole Jegede, Inderpreet Virk, Karthik Cherukupally, Wil Germain, Patricia Fouron, Tolu Olupona, et al.From:Case Reports in Psychiatry (Vol. 2018) Peer-Reviewed

  Annual 20182,290 words Article 1400LThe core symptomatology of the Olfactory Reference Syndrome (ORS) is characterized by a preoccupation with the belief that one emits an offensive odor, albeit not perceived by others. The present case is that of a...

• The antipsychotic drug pimozide inhibits cell growth in prostate cancer through suppression of STAT3 activation

  Authors:Wei Zhou, Ming-Kun Chen, Hao-Tao Yu, Zhi-Hong Zhong, Nan Cai, Guan-Zhong Chen, et al.From:International Journal of Oncology (Vol. 48, Issue 1) Peer-Reviewed

  Jan. 20164,030 words Report 1480LAbstract. Currently, drug discovery and development for clinical treatment of prostate cancer has received increased attention, specifically the STAT3 inhibitor. Our previous study reported that the neuroleptic drug...

• Fluspirilene/haloperidol/pimozide: tardive dystonia: 4 case reports

  From:Reactions Weekly (Issue 1319)

  Sept. 18, 2010335 words Brief article, Case ... 1150LFour women developed tardive dystonia following treatment with either fluspirilene, haloperidol or fluspirilene and pimozide for either mild depression, nervousness or mild depression and neurasthenia [dosages and...

• Risperidone was as effective as pimozide for Tourette's disorder

  From:Evidence-Based Mental Health (Vol. 4, Issue 3) Peer-Reviewed

  Aug. 2001791 words Article Bruggeman R, van der Linden C, Buitelaar JK, et al. Risperidone versus pimozide in Tourette's disorder: a comparative double-blind parallel-group study. J Clin Psychiatry 2001 Jan;62:50--6. QUESTION: In patients with...

• Findings from Henan University Provides New Data on Xenografts (Pimozide Augments Bromocriptine Lethality In Prolactinoma Cells and In a Xenograft Model Via the Stat5/cyclin D1 and Stat5/bcl-xl Signaling Pathways).

  From:Stem Cell Week

  Feb. 1, 2021571 words Article 1510L2021 FEB 1 (NewsRx) -- By a News Reporter-Staff News Editor at Stem Cell Week -- A new study on Biotechnology - Xenografts is now available. According to news originating from Henan, People's Republic of China, by NewsRx...