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    Academic Journals

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• Select Proteolytic profiling and comparative analyses of active trypsin-like serine peptidases in preimaginal stages of Culex quinquefasciatus

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  Proteolytic profiling and comparative analyses of active trypsin-like serine peptidases in preimaginal stages of Culex quinquefasciatus

  Authors:Andre Borges-Veloso, Leonardo Saboia-Vahia, Patricia Cuervo, Renata C Pires, Constanca Britto, Nilma Fernandes, et al.From:Parasites & Vectors (Vol. 5, Issue 1) Peer-Reviewed

  June 20, 20126,630 words Report 1440LBackground The mosquito Culex quinquefasciatu s, a widespread insect in tropical and sub-tropical regions of the world, is a vector of multiple arboviruses and parasites, and is considered an important risk to human...
• Select The family of Deg/HtrA proteases in plants

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  The family of Deg/HtrA proteases in plants

  Authors:Holger Schuhmann, Pitter F Huesgen, and Iwona AdamskaFrom:BMC Plant Biology (Vol. 12, Issue 1) Peer-Reviewed

  Apr. 20, 20126,046 words Report 1540LBackground The Deg/HtrA family of ATP-independent serine endopeptidases is present in nearly all organisms from bacteria to human and vascular plants. In recent years, multiple deg/htrA protease genes were identified...
• Select The elevation of serum napsin A in idiopathic pulmonary fibrosis, compared with KL-6, surfactant protein-A and surfactant protein-D

  3

  The elevation of serum napsin A in idiopathic pulmonary fibrosis, compared with KL-6, surfactant protein-A and surfactant protein-D

  Authors:Takuya Samukawa, Tsutomu Hamada, Hirofumi Uto, Masakazu Yanagi, Go Tsukuya, Tsuyoshi Nosaki, et al.From:BMC Pulmonary Medicine (Vol. 12, Issue 1) Peer-Reviewed

  Sept. 11, 20124,490 words Report 1430LBackground Napsin A, an aspartic protease, is mainly expressed in alveolar type-II cells and renal proximal tubules and is a putative immunohistochemical marker for pulmonary adenocarcinomas. This study sought to...
• Select Modeling and structural analysis of PA clan serine proteases

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  Modeling and structural analysis of PA clan serine proteases

  Authors:Aparna Laskar, Euan J Rodger, Aniruddha Chatterjee, and Chhabinath MandalFrom:BMC Research Notes (Vol. 5, Issue 1) Peer-Reviewed

  May 24, 20125,646 words Report 1530LBackground Serine proteases account for over a third of all known proteolytic enzymes; they are involved in a variety of physiological processes and are classified into clans sharing structural homology. The PA clan...
• Select Olysio.

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  Olysio.

  From:MPR - Physician Assistants' Edition (Vol. 21, Issue 1)

  Spring 2014152 words Brief article 1080LCompany: Janssen Therapeutics | Rx Pharmacologic class: Hepatitis C virus (HCV) NS3/4A protease inhibitor. Active ingredient: Simeprevir 150mg; capsules. Indication: Chronic hepatitis C (CHC) genotype 1 infection,...
• Select Viekira Pak.

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  Viekira Pak.

  From:MPR - Physician Assistants' Edition (Vol. 22, Issue 2)

  Summer 2015162 words Brief article 970LCompany: AbbVie | Rx Pharmacologic class: HCV NS5A inhibitor/HCV NS3/4A protease inhibitor/ CYP3A inhibitor + HCV non-nucleoside NS5B palm polymerase inhibitor Active ingredients: Ombitasvir/paritaprevir/ ritonavir;...
• Select Zepatier.

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  Zepatier.

  From:MPR - Physician Assistants' Edition (Vol. 23, Issue 2)

  Summer 2016300 words Brief article 1380LCompany: Merck Rx Pharmacologic class: HCV NS5A inhibitor + HCV NS3/4A protease inhibitor Active ingredients: Elbasvir, grazoprevir 50mg/100mg; tablets. Indication: Chronic HCV genotypes 1 or 4 infection with or...
• Select Technivie.

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  Technivie.

  From:MPR - Physician Assistants' Edition (Vol. 22, Issue 4)

  Winter 2015166 words Brief article 1210LCompany: AbbVie | Rx Pharmacologic class: HCV NS5A inhibitor + HCV NS3/4A protease inhibitor + CYP3A inhibitor Active ingredients: Ombi tasvir 12.5mg, paritaprevir 75mg, ritonavir 50mg; tablets. Indication: In...
• Select Evotaz.

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  Evotaz.

  From:MPR - Physician Assistants' Edition (Vol. 22, Issue 3)

  Fall 2015155 words Brief article 1090LCompany : Bristol-Myers Squibb | Rx Pharmacologic class: HIV-1 protease inhibitor + CYP3A inhibitor Active ingredients: Atazanavir 300mg, cobici stat 150mg; tablets. Indication: HIV-1 infection in combination with...
• Select Zontivity

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  Zontivity

  From:Nurse Practitioners' Prescribing Reference (Vol. 21, Issue 3) Peer-Reviewed

  Fall 2014168 words Brief article 1200L Company: Merck | Rx Pharmacologic class: Protease-activated receptor-1 (PAR-1) antagonist. Active ingredients: Vorapaxar 2.08mg (equivalent to 2.5 mg of vorapaxar sulfate); tablets....
• Select Prezcobix.

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  Prezcobix.

  From:MPR - Physician Assistants' Edition (Vol. 22, Issue 3)

  Fall 2015148 words Brief article 1200LCompany : Janssen | Rx Pharmacologic class: HIV-1 protease inhibitor + CYP3A inhibitor Active ingredients: Darunavir 800mg, cobicistat 150mg; tablets. Indication: In combination with other antiretroviral agents for...
• Select MMP-9 (-1562 C:T) polymorphism as a biomarker of susceptibility to severe pre-eclampsia

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  MMP-9 (-1562 C:T) polymorphism as a biomarker of susceptibility to severe pre-eclampsia

  Authors:Zohreh Rahimi, Ziba Rahimi, Maria Omidi Shahsavandi, Kazem Bidoki, and Mansour RezaeiFrom:Biomarkers in Medicine (Vol. 7, Issue 1) Peer-Reviewed

  Feb. 20134,107 words Report 1360LAuthor(s): Zohreh Rahimi [*] 4 2 , Ziba Rahimi 1 , Maria Omidi Shahsavandi 1 , Kazem Bidoki 1 , Mansour Rezaei 3 KEYWORDS : early-onset pre-eclampsia; MMP-9 polymorphism; severe pre-eclampsia; western Iran...
• Select Ellagic acid & gallic acid from Lagerstroemia speciosa L. inhibit HIV-1 infection through inhibition of HIV-1 protease & reverse transcriptase activity

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  Ellagic acid & gallic acid from Lagerstroemia speciosa L. inhibit HIV-1 infection through inhibition of HIV-1 protease & reverse transcriptase activity

  Authors:Nutan, Manoj Modi, Tanvi Goel, Tiyasa Das, Shweta Malik, Samiksha Suri, et al.From:Indian Journal of Medical Research (Vol. 137, Issue 3) Peer-Reviewed

  Mar. 20134,592 words Report 1490LByline: Nutan, Manoj. Modi, Tanvi. Goel, Tiyasa. Das, Shweta. Malik, Samiksha. Suri, Ajay. Rawat, Sharad. Srivastava, Rakesh. Tuli, Swadesh. Malhotra, Satish. Gupta Background & objectives: Banaba (Lagerstroemia...
• Select Synthesis and pharmacological activity of amino alcohols of the indole series

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  Synthesis and pharmacological activity of amino alcohols of the indole series

  Authors:K.F. Suzdalev, A.A. Spasov, D.S. Yakovlev, V.A. Kosolapov, A.F. Kucheryavenko, N.A. Gurova, et al.From:Pharmaceutical Chemistry Journal (Vol. 47, Issue 3) Peer-Reviewed

  June 20132,056 words Report 1410LOpening of the oxirane ring in 1-oxiranylmethylindoles yielded new indole derivatives containin 1,2-amino alcohol residues at the nitrogen atom. Compounds were studied in vitro in relation to various types of...
• Select New Helicobacter pylori Findings Reported from National Tsing Hua University (Lon protease affects the RdxA nitroreductase activity and metronidazole susceptibility in Helicobacter pylori)

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  New Helicobacter pylori Findings Reported from National Tsing Hua University (Lon protease affects the RdxA nitroreductase activity and metronidazole susceptibility in Helicobacter pylori)

  From:Obesity, Fitness & Wellness Week

  June 20, 2015422 words Report 1320L2015 JUN 20 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Fresh data on Gastroenterology are presented in a new report. According to news reporting originating in Hsinchu,...
• Select Conversion of amides to esters by the nickel-catalysed activation of amide C-N bonds

  16

  Conversion of amides to esters by the nickel-catalysed activation of amide C-N bonds

  Authors:Liana Hie, Noah F. Fine Nathel, Tejas K. Shah, Emma L. Baker, Xin Hong, Yun-Fang Yang, et al.From:Nature (Vol. 524, Issue 7563) Peer-Reviewed

  Aug. 6, 20153,329 words Report 1420LAmides are common functional groups that have been studied for more than a century (1). They are the key building blocks of proteins and are present in a broad range of other natural and synthetic compounds. Amides are...
• Select Studies from RIKEN Yield New Information about Cysteine Endopeptidases

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  Studies from RIKEN Yield New Information about Cysteine Endopeptidases

  From:Obesity, Fitness & Wellness Week

  Feb. 25, 2012286 words Brief article 1430L"The caspases, a family of cysteine proteases, function as central regulators of cell death. Recently, caspase activity and caspase substrates identified in the absence of cell death have sparked strong interest in...
• Select Findings on Cushing Syndrome and Genetics Discussed by Investigators at School of Life Science and Technology (The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's Disease)

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  Findings on Cushing Syndrome and Genetics Discussed by Investigators at School of Life Science and Technology (The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's Disease)

  From:Obesity, Fitness & Wellness Week

  Oct. 10, 2015507 words Article 1360L2015 OCT 10 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators discuss new findings in Adrenal Gland Diseases. According to news reporting originating from Bandung,...
• Select Research on Blood Coagulation Factors Reported by Scientists at Veterans Affairs Medical Center

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  Research on Blood Coagulation Factors Reported by Scientists at Veterans Affairs Medical Center

  From:Obesity, Fitness & Wellness Week

  May 21, 2011352 words Brief article 1520LA new study, 'A membrane-interactive surface on the factor VIII C1 domain cooperates with the C2 domain for cofactor function,' is now available. According to recent research from Boston, United States, "Factor VIII...
• Select Studies from Cleveland Clinic Foundation Provide New Data on Thrombosis

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  Studies from Cleveland Clinic Foundation Provide New Data on Thrombosis

  From:Obesity, Fitness & Wellness Week

  Apr. 30, 2011396 words Report 1440LScientists discuss in 'Thrombin induces endothelial arginase through AP-1 activation' new findings in Thrombosis. According to a study from Cleveland, United States, "Arterial thrombosis is a common disease leading to...