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• Select Gene expression in the squid giant axon: neurotransmitter modulation of RNA transfer from periaxonal glia to the axon

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  Gene expression in the squid giant axon: neurotransmitter modulation of RNA transfer from periaxonal glia to the axon

  Authors:Antonio Giuditta, Maria Eyman, and Barry B. KaplanFrom:The Biological Bulletin (Vol. 203, Issue 2) Peer-Reviewed

  Oct. 2002911 words Article The presence of RNA in axons has been known for nearly 40 years (1). In large model axons, such as the goldfish Mauthner axon and the squid giant axon, axoplasmic RNA includes the main cytoplasmic species, that is,...
• Select A plausible role for the presence of internal Shine-Dalgarno sites

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  A plausible role for the presence of internal Shine-Dalgarno sites

  Author:Lalit PonnalaFrom:Bioinformatics and Biology InsightsPeer-Reviewed

  June 28, 20102,508 words Report 1620LThe presence of nucleotide hybridization between the 3' end of 16S rRNA and mRNA sequence upstream of the start codon is well known in bacteria. In this paper, we detect the presence of such hybridization sites inside...
• Select RNA decay: The exosome TRAMPs on viral RNA

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  RNA decay: The exosome TRAMPs on viral RNA

  Author:Eytan ZlotorynskiFrom:Nature Reviews Molecular Cell Biology (Vol. 17, Issue 9) Peer-Reviewed

  Sept. 2016167 words Author abstract, Bri... 1670LAuthor(s): Eytan Zlotorynski Performing RNAi screens for factors that restrict several RNA viruses in fruit flies, Molleston et al . discovered that depletion of the 3' to 5' exonucleases dRrp6 or dDis3, which are...
• Select The 5' Spreading of Small RNAs in Dictyostelium discoideum Depends on the RNA-Dependent RNA Polymerase RrpC and on the Dicer-Related Nuclease DrnB

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  The 5' Spreading of Small RNAs in Dictyostelium discoideum Depends on the RNA-Dependent RNA Polymerase RrpC and on the Dicer-Related Nuclease DrnB

  Authors:Stephan Wiegand and Christian HammannFrom:PLoS ONE (Vol. 8, Issue 5) Peer-Reviewed

  May 20, 20136,922 words Article 1560LAuthor(s): Stephan Wiegand, Christian Hammann * Introduction Double stranded RNA is the central nucleic acid entity in the gene regulatory mechanism RNA interference (RNAi) [1] that acts in many eukaryotes....
• Select New Molecular Science Data Have Been Reported by Researchers at Polish Academy of Sciences (Reprogramming mRNA Expression in Response to Defect in RNA Polymerase III Assembly in the Yeast * * Saccharomyces cerevisiae* *).

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  New Molecular Science Data Have Been Reported by Researchers at Polish Academy of Sciences (Reprogramming mRNA Expression in Response to Defect in RNA Polymerase III Assembly in the Yeast * * Saccharomyces cerevisiae* *).

  From:Obesity, Fitness & Wellness Week

  Aug. 14, 2021503 words Article 1380L2021 AUG 14 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New study results on molecular science have been published. According to news reporting from Warsaw, Poland, by NewsRx...
• Select Rice stripe virus infection alters mRNA levels of sphingolipid-metabolizing enzymes and sphingolipids content in Laodelphax striatellus

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  Rice stripe virus infection alters mRNA levels of sphingolipid-metabolizing enzymes and sphingolipids content in Laodelphax striatellus

  Authors:Wen-Juan Jiao, Fei-Qiang Li, Yue-Liang Bai, Xiao-Xiao Shi, Mu-Fei Zhu, Min-Jing Zhang, et al.From:Journal of Insect Science (Vol. 17, Issue 1) Peer-Reviewed

  Jan. 20174,700 words Report 1530LSphingolipids and their metabolites have been implicated in viral infection and replication in mammal cells but how their metabolizing enzymes in the host are regulated by viruses remains largely unknown. Here we report...
• Select Data on Klebsiella Detailed by Researchers at Huazhong University of Science and Technology (Klebsiella Phage KP34 RNA Polymerase and Its Use in RNA Synthesis).

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  Data on Klebsiella Detailed by Researchers at Huazhong University of Science and Technology (Klebsiella Phage KP34 RNA Polymerase and Its Use in RNA Synthesis).

  From:Obesity, Fitness & Wellness Week

  Nov. 23, 2019392 words Report, Brief articl... 1290L2019 NOV 23 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on klebsiella are discussed in a new report. According to news originating from Wuhan, People's...
• Select Messenger RNA transport and HIV rev regulation

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  Messenger RNA transport and HIV rev regulation

  Authors:David D. Chang and Phillip A. SharpFrom:Science (Vol. 249, Issue 4969) Peer-Reviewed

  Aug. 10, 19902,008 words Article The mechanism of transport of messenger ribose nucleic acid (mRNA) molecules from the nucleus of the cell where they are synthesized from genes, to the cytoplasm of the cell, where proteins are synthesized from them, is...
• Select Understanding biases in ribosome profiling experiments reveals signatures of translation dynamics in yeast

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  Understanding biases in ribosome profiling experiments reveals signatures of translation dynamics in yeast

  Authors:Jeffrey A. Hussmann, Stephanie Patchett, Arlen Johnson, Sara Sawyer, and William H. PressFrom:PLoS Genetics (Vol. 11, Issue 12) Peer-Reviewed

  Dec. 201510,530 words Report 1630LRibosome profiling produces snapshots of the locations of actively translating ribosomes on messenger RNAs. These snapshots can be used to make inferences about translation dynamics. Recent ribosome profiling studies in...
• Select Contribution of natural antisense transcription to an endogenous siRNA signature in human cells

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  Contribution of natural antisense transcription to an endogenous siRNA signature in human cells

  Authors:Andreas Werner, Simon Cockell, Jane Falconer, Mark Carlile, Sammer Alnumeir, and John RobinsonFrom:BMC Genomics (Vol. 15, Issue 1) Peer-Reviewed

  Jan. 13, 20146,579 words Article 1360LAuthor(s): Andreas Werner1 , Simon Cockell2 , Jane Falconer3 , Mark Carlile4 , Sammer Alnumeir1 and John Robinson5 Background The full nature of the human transcriptome is taking shape thanks to highly efficient...
• Select Mitochondrial Polyadenylation Is a One-Step Process Required for mRNA Integrity and tRNA Maturation

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  Mitochondrial Polyadenylation Is a One-Step Process Required for mRNA Integrity and tRNA Maturation

  Authors:Ana Bratic, Paula Clemente, Javier Calvo-Garrido, Camilla Maffezzini, Andrea Felser, Rolf Wibom, et al.From:PLoS Genetics (Vol. 12, Issue 5) Peer-Reviewed

  May 13, 20168,987 words Report 1540LPolyadenylation has well characterised roles in RNA turnover and translation in a variety of biological systems. While polyadenylation on mitochondrial transcripts has been suggested to be a two-step process required to...
• Select Modification of [tRNA.sup.Lys.sub.UUU] by Elongator is essential for efficient translation of stress mRNAs

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  Modification of [tRNA.sup.Lys.sub.UUU] by Elongator is essential for efficient translation of stress mRNAs

  Authors:Jorge Fernandez-Vazquez, Itzel Vargas-Perez, Miriam Sanso, Karin Buhne, Merce Carmona, Esther Paulo, et al.From:PLoS Genetics (Vol. 9, Issue 7) Peer-Reviewed

  July 20138,238 words Report 1570LThe Elongator complex, including the histone acetyl transferase Sin3/Elp3, was isolated as an RNA polymerase II- interacting complex, and cells deficient in Elongator subunits display transcriptional defects. However,...
• Select Recent Findings from State University of New York Has Provided New Information about Picornaviridae (Initiation of protein-primed picornavirus RNA synthesis)

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  Recent Findings from State University of New York Has Provided New Information about Picornaviridae (Initiation of protein-primed picornavirus RNA synthesis)

  From:Obesity, Fitness & Wellness Week

  Aug. 1, 2015342 words Brief article 1450L2015 AUG 1 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Researchers detail new data in Picornaviridae. According to news originating from Stony Brook, New York, by NewsRx...
• Select Research from N.G. Iglesias et al Broadens Understanding of Dengue Fever

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  Research from N.G. Iglesias et al Broadens Understanding of Dengue Fever

  From:Obesity, Fitness & Wellness Week

  July 16, 2011398 words Article 1390LAccording to the authors of a study from Buenos Aires, Argentina, "The mechanism by which viral RNA-dependent RNA polymerases (RdRp) specifically amplify viral genomes is still unclear. In the case of flaviviruses, a...
• Select Active Center Control of Termination by RNA Polymerase III and tRNA Gene Transcription Levels In Vivo

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  Active Center Control of Termination by RNA Polymerase III and tRNA Gene Transcription Levels In Vivo

  Authors:Keshab Rijal and Richard J. MaraiaFrom:PLoS Genetics (Vol. 12, Issue 8) Peer-Reviewed

  Aug. 12, 201614,111 words Report 1530LThe ability of RNA polymerase (RNAP) III to efficiently recycle from termination to reinitiation is critical for abundant tRNA production during cellular proliferation, development and cancer. Yet understanding of the...
• Select Development of a Multipurpose GATEWAY-Based Lentiviral Tetracycline-Regulated Conditional RNAi System (GLTR)

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  Development of a Multipurpose GATEWAY-Based Lentiviral Tetracycline-Regulated Conditional RNAi System (GLTR)

  Authors:Reinhard Sigl, Christian Ploner, Giridhar Shivalingaiah, Reinhard Kofler, and Stephan GeleyFrom:PLoS ONE (Vol. 9, Issue 5) Peer-Reviewed

  May 19, 20145,637 words Article 1590LRNA interference (RNAi) has become an essential technology for functional gene analysis. Its success, however, depends on the effective expression of RNAi-inducing small double-stranded interfering RNA molecules...
• Select Strand-specific RNA-Seq reveals widespread and developmentally regulated transcription of natural antisense transcripts in Plasmodium falciparum

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  Strand-specific RNA-Seq reveals widespread and developmentally regulated transcription of natural antisense transcripts in Plasmodium falciparum

  Authors:T Nicolai Siegel, Chung-Chau Hon, Qinfeng Zhang, Jose-Juan Lopez-Rubio, Christine Scheidig-Benatar, Rafael M Martins, et al.From:BMC Genomics (Vol. 15, Issue 1) Peer-Reviewed

  Feb. 22, 201410,484 words Article 1520LBackground Advances in high-throughput sequencing have led to the discovery of widespread transcription of natural antisense transcripts (NATs) in a large number of organisms, where these transcripts have been shown...
• Select Vex-seq: high-throughput identification of the impact of genetic variation on pre-mRNA splicing efficiency

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  Vex-seq: high-throughput identification of the impact of genetic variation on pre-mRNA splicing efficiency

  Authors:Scott I. Adamson, Lijun Zhan, and Brenton R. GraveleyFrom:Genome Biology (Vol. 19, Issue 1) Peer-Reviewed

  June 1, 20185,830 words Report 1400LUnderstanding the functional impact of genomic variants is a major goal of modern genetics and personalized medicine. Although many synonymous and non-coding variants act through altering the efficiency of pre-mRNA...
• Select Assessment of the genetic relationship between Dictyocaulus species from Bos taurus and Cervus elaphus using complete mitochondrial genomic datasets

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  Assessment of the genetic relationship between Dictyocaulus species from Bos taurus and Cervus elaphus using complete mitochondrial genomic datasets

  Authors:Robin B Gasser, Abdul Jabbar, Namitha Mohandas, Johan Hoglund, Ross S Hall, D Timothy J Littlewood, et al.From:Parasites & Vectors (Vol. 5, Issue 1) Peer-Reviewed

  Oct. 30, 20127,037 words Report 1690LBackground Dictyocaulus species are strongylid nematodes of major veterinary significance in ruminants, such as cattle and cervids, and cause serious bronchitis or pneumonia (dictyocaulosis or "husk"). There has been...
• Select Research from University of Heidelberg Yields New Findings on Hepatitis C Virus (Evidence for internal initiation of RNA synthesis by the Hepatitis C virus RNA-dependent RNA polymerase NS5B in cellulo)

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  Research from University of Heidelberg Yields New Findings on Hepatitis C Virus (Evidence for internal initiation of RNA synthesis by the Hepatitis C virus RNA-dependent RNA polymerase NS5B in cellulo)

  From:Obesity, Fitness & Wellness Week

  Aug. 3, 2019659 words Report 1560L2019 AUG 3 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on Liver Diseases and Conditions - Hepatitis C Virus have been published. According to news...