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Academic Journals
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From:Neural Regeneration Research (Vol. 8, Issue 33) Peer-ReviewedByline: Yiming. Ji, Bin. Meng, Chenxi. Yuan, Huilin. Yang, Jun. Zou Research Highlights (1) Intraoperative monitoring of somatosensory evoked potentials is regarded a new measure to avoid iatrogenic spinal cord...
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From:Future Cardiology (Vol. 11, Issue 1) Peer-ReviewedAuthor(s): Guramrinder S Thind aff1 , Pratik R Agrawal aff2 aff3 , Benjamin Hirsh aff2 , Louis Saravolatz aff4 , Carol Chen-Scarabelli aff5 , Jagat Narula aff2 , Tiziano M Scarabelli [*] aff2 aff4 KEYWORDS...
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From:Neural Regeneration Research (Vol. 10, Issue 6) Peer-ReviewedByline: Xin-juan. Li, Chao-kun. Li, Lin-yu. Wei, Na. Lu, Guo-hong. Wang, Hong-gang. Zhao, Dong-liang. Li The present study aimed to explore the mechanism underlying the protective effects of hydrogen sulfide against...
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From:PLoS ONE (Vol. 7, Issue 1) Peer-ReviewedAuthor(s): Peter F. Mount 1 , 2 , * , Kurt Gleich 1 , 2 , Shanna Tam 3 , Scott A. Fraser 1 , 2 , Suet-Wan Choy 1 , 2 , 4 , Karen M. Dwyer 5 , Bo Lu 5 , Bryce Van Denderen 3 , Günter Fingerle-Rowson 6 , Richard Bucala 7...
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From:Stem Cells InternationalPeer-ReviewedBackground. The immoderation of mitochondrial fission is one of the main contributors in ischemia reperfusion injury (IRI) and mesenchymal stromal cells (MSCs) derived extracellular vesicles have been regarded as a...
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From:Canadian Journal of Physiology and Pharmacology (Vol. 94, Issue 1) Peer-ReviewedRecent studies have demonstrated that ginsenoside Rb1 protects the myocardium from ischemia-reperfusion (I/R) injury. However, the precise mechanisms for this protection have not been determined. This study aimed to...
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From:Canadian Journal of Physiology and Pharmacology (Vol. 84, Issue 8-9) Peer-ReviewedAbstract: Whole-body heat shock (HS) leads to an enhancement of postischemic mechanical function and an improvement in glucose use by the rat heart. Here, we examine the effect of HS on isolated mitochondrial metabolism...
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From:Diabetes (Vol. 46, Issue 2) Peer-ReviewedDiabetes increases the incidence of cardiovascular disease as well as the complications of myocardial infarction. Studies using animal models of diabetes have demonstrated that the metabolic alterations occurring at the...
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From:Stroke Research and TreatmentPeer-ReviewedNADPH oxidase is a major source of superoxide anion following stroke and reperfusion. This study evaluated the effects of apocynin, a known antioxidant and inhibitor of Nox2 NADPH, on neuronal injury and cell-specific...
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From:Oxidative Medicine and Cellular Longevity (Vol. 2017) Peer-ReviewedPropofol pretreatment before reperfusion, or propofol conditioning, has been shown to be cardioprotective, while its mechanism is unclear. The current study investigated the roles of endocannabinoid signaling in...
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From:PLoS ONE (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Jung Pyo Lee 1 , 2 , 3 , Seung Hee Yang 2 , 3 , Hee-Yoon Lee 4 , Bora Kim 5 , Joo-Youn Cho 5 , Jin Ho Paik 6 , Yun Jung Oh 3 , Dong Ki Kim 2 , 3 , Chun Soo Lim 1 , 2 , 3 , Yon Su Kim 2 , 3 , * Introduction...
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From:Neural Regeneration Research (Vol. 15, Issue 10) Peer-ReviewedByline: Maryna. Basalay, Sean. Davidson, Derek. Yellon Currently, ischemic stroke remains one of the most costly and devastating clinical syndromes, accounting for 9% of all deaths and being the second leading cause...
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From:Phytomedicine: International Journal of Phytotherapy & Phytopharmacology (Vol. 17, Issue 10) Peer-ReviewedABSTRACT The aim of the study was to investigate the cardioprotective effect and mechanism of Crataegus oxycantha (COC) extract, a well-known natural antioxidant-based cardiotonic, against ischemia/reperfusion (I/R)...
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From:BioMed Research InternationalPeer-ReviewedMatrix metalloproteinases (MMPs) significantly contribute to ischemia reperfusion (I/R) injury, namely, by the degradation of contractile proteins. However, due to the experimental models adopted and lack of isoform...
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From:PeerJ (Vol. 8) Peer-ReviewedWith the aim of exploring expression profiles and biological functions of long non-coding RNA (lncRNA) and mRNAs after spinal cord ischemia-reperfusion injury (SCII), differentially expressed lncRNAs (DElncRNAs) and...
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From:BioMed Research InternationalPeer-ReviewedMyocardial ischemia/reperfusion (MIR) injury easily occurrs during cardiopulmonary bypass surgery in elderly patients. In an attempt to develop an effective strategy, we employed a pig model of MIR injury to investigate...
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From:Canadian Journal of Physiology and Pharmacology (Vol. 98, Issue 12) Peer-ReviewedThe objective was to identify the differential expressed miRNA during cerebral ischemia-reperfusion injury (CIRI) process, thereby assisting in elucidating the mechanism of CIRI development and providing a potential...
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From:PLoS ONE (Vol. 12, Issue 4) Peer-ReviewedPrevious studies have indicated that hepcidin, which can regulate iron efflux by binding to ferroportin-1 (FPN1) and inducing its internalization and degradation, acts as the critical factor in the regulation of iron...
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From:Gene Therapy (Vol. 15, Issue 6) Peer-ReviewedTransforming growth factor [[beta].sub.1] (TGF[[beta].sub.1]) has been purported to protect tissues from ischemia-reperfusion (I-R) injury. This study was designed to examine if overexpression of TGF[[beta].sub.1] using...
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From:Journal of Clinical Investigation (Vol. 119, Issue 6) Peer-ReviewedThe ability of glucocorticoids to mediate cardioprotective effects in the setting of acute myocardial ischemia/reperfusion has largely been attributed to their antiinflammatory effects. However, Tokudome and colleagues...