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From:Nature (Vol. 513, Issue 7516) Peer-ReviewedThe loss of cells in the retina might predict a common type of dementia years before behavioural changes set in. A team led by Li Gan and Ari Green at the University of California, San Francisco, imaged the retinas...
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From:The Biological Bulletin (Vol. 187, Issue 2) Peer-ReviewedPrevious studies have concluded that quinine and its stereoisomer, quinidine, have potent effects on the nervous system, particularly on the visual system. Using a whole-cell version of the patch-clamp technique,...
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From:British Medical Journal (Vol. 312, Issue 7032) Peer-ReviewedObjective - To evaluate whether adding retinal photography improved community screening for diabetic retinopathy. Setting - mobile screening unit at rural and urban general practices in south west England. Subjects -...
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From:Nature (Vol. 546, Issue 7658) Peer-ReviewedAuthor(s): Paul A. Sieving (corresponding author) [1] The National Eye Institute of the US National Institutes of Health (NIH) has launched a competition to develop a working model of the human retina from stem cells...
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From:The Biological Bulletin (Vol. 205, Issue 2) Peer-ReviewedThe vertebrate retina is a highly specialized sheet of neural tissue derived from an undifferentiated population of neural progenitor cells, which, upon completion of their final division, migrate to their laminar...
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From:Ophthalmology Times (Vol. 40, Issue 1) Peer-ReviewedNEW YORK :: These days, it is commonplace to use optical coherence tomography (OCT) to measure retinal nerve fiber layer (RNFL) thinning with optic nerve injury, due to glaucoma, optic neuritis, or ischemic optic...
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From:Stem Cells International (Vol. 2017) Peer-ReviewedIn humans and other mammals, the neural retina does not spontaneously regenerate, and damage to the retina that kills retinal neurons results in permanent blindness. In contrast to embryonic stem cells, induced...
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From:Review of Optometry (Vol. 155, Issue 10) Peer-ReviewedThe future of vision prosthetics has gained momentum thanks to several new technological developments, including an artificial retina and what researchers are calling a "bionic eye." (1-4) New Retinas in the Pipeline...
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From:Genetics Research InternationalPeer-ReviewedWe performed transcriptome sequencing of canine retinal tissue by 454 GS-FLX and Ion Torrent PGM platforms. RNA-Seq analysis by CLC Genomics Workbench mapped expression of 10,360 genes. Gene ontology analysis of retinal...
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From:Journal of Medical Signals & Sensors (Vol. 11, Issue 1) Peer-ReviewedByline: Tahereh. Mahmudi, Raheleh. Kafieh, Hossein. Rabbani, Alireza. Mehri, Mohammad-Reza. Akhlaghi Background: Asymmetry analysis of retinal layers in right and left eyes can be a valuable tool for early diagnoses...
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From:PLoS ONE (Vol. 13, Issue 4) Peer-ReviewedObjective To analyse the morphological features and diagnostic ability of eight macular retinal layers using a new segmentation software Heidelberg's Spectralis Optical Coherence Tomography (SD-OCT) in healthy,...
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From:PLoS ONE (Vol. 13, Issue 5) Peer-ReviewedRetinitis pigmentosa (RP), an inherited retinal degenerative disease, is characterized by a progressive loss of rod photoreceptors followed by loss of cone photoreceptors. Previously, when tissue inhibitor of...
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From:PLoS ONE (Vol. 12, Issue 6) Peer-ReviewedPurpose To quantitatively investigate the characteristics of eyes with pituitary adenoma presented by three-dimensional (3D) spectral-domain optical coherence tomography (SD-OCT) using three common indices, including...
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From:Nature (Vol. 561, Issue 7721) Peer-ReviewedDamage to the retina has so far proved irreversible, but stem-cell therapies could hold the key to restoring sight. Damage to the retina has so far proved irreversible, but stem-cell therapies could hold the key to...
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From:Review of Optometry (Vol. 148, Issue 8) Peer-ReviewedRetina imaging, along with other biomarker tests, may be able to aid in early detection of Alzheimer's disease (AD), according to a study presented at the Alzheimer's Association International Conference in July. (1)...
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From:Review of Optometry (Vol. 138, Issue 7) Peer-ReviewedGDx: Early diagnosis is the key. The GDx is a powerful diagnostic tool that can help us evaluate the glaucoma suspects we see every day in clinical practice. In many cases, it's not enough for us to perform visual...
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From:Nature (Vol. 546, Issue 7659) Peer-ReviewedAuthor(s): Jonathan B. Demb (corresponding author) [1]; Damon A. Clark (corresponding author) [2] Body movements generate inputs to two independent sensory systems: the vestibular system, which provides a sense of...
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From:PLoS ONE (Vol. 16, Issue 10) Peer-ReviewedIn daylight, cone photoreceptors in the retina are responsible for the bulk of visual perception, yet compared to rods, far less is known quantitatively about their biochemistry. This is partly because it is hard to...
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From:British Journal of Ophthalmology (Vol. 87, Issue 4) Peer-ReviewedBackground/aims: The retina possesses a rich network of [CD45.sup.+] positive myeloid derived cells that both surround inner retinal vessels and lie within the retina (microglia). Microglia migrate and accumulate in...
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From:Journal of Diabetes Research (Vol. 2014) Peer-ReviewedThis paper aims to explore the relationship of retinal neuron apoptosis and manganese superoxidase dismutase (MnSOD) at early phase of diabetic retinopathy. Sprague-Dawley rats were grouped into normal controls and...