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    Academic Journals

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• Viread for treating children

  From:MPR Pharmacists' Edition (Vol. 6, Issue 1)

  Spring 201277 words Brief article 1250LViread (tenofovir disoproxil fumarate; Gilead) has been approved for use in combination with other antiretroviral agents for the treatment of HIV-1 infection in pediatric patients 2-12 years old. Additionally, the...

• An explanation in nanostructure level based on the view of energy change for G333d mutation relating to drug resistance in HIV-1 reverse transcriptase

  Author:V. WiwanitkitFrom:Indian Journal of Medical Microbiology (Vol. 26, Issue 2)

  April-June 2008762 words Article 1540LByline: V. Wiwanitkit Dear editor, Human immunodeficiency virus (HIV) infection is an important infection affecting a million of world population. The best present way in coping with the patients with HIV is...

• Distal sensory polyneuropathy in human immunodeficiency virus patients and nucleoside analogue antiretroviral agents

  Authors:Jimmy Jose, Kavitha Saravu, Beena Jimmy, and B. ShastryFrom:Annals of Indian Academy of Neurology (Vol. 10, Issue 2) Peer-Reviewed

  April-June 20075,097 words Clinical report 2240LByline: Jimmy. Jose, Kavitha. Saravu, Beena. Jimmy, B. Shastry Distal sensory polyneuropathy, which occur commonly in human immunodeficiency virus (HIV) patients can occur as a consequence of the disease itself or...

• Gastrointestinal permeability studies using combinations of rifampicin and nucleoside analogue reverse transcriptase inhibitors in rats

  Authors:T. Mariappan and Saranjit SinghFrom:Indian Journal of Pharmacology (Vol. 39, Issue 6) Peer-Reviewed

  November-December 20073,332 words Report 1260LByline: T. Mariappan, Saranjit. Singh Objectives: To investigate the gastrointestinal tract (GIT) permeability of five nucleoside analogue reverse transcriptase inhibitors (NRTIs), viz., zidovudine, stavudine,...

• Polymorphisms in the telomerase reverse transcriptase promoter are associated with risk of breast cancer: A meta-analysis

  Authors:Zhen-Yu Li, Ying-Li Dong, Yun Feng, Zhen Zhang, and Xiao-Zhong CaoFrom:Journal of Cancer Research and Therapeutics (Vol. 12, Issue 2) Peer-Reviewed

  April-June 20162,286 words Report 1290LByline: Zhen-Yu. Li, Ying-Li. Dong, Yun. Feng, Zhen. Zhang, Xiao-Zhong. Cao Aims: Recently, the relationship between telomerase reverse transcriptase (TERT) polymorphisms and breast cancer risk has been investigated...

• An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA

  Authors:Yoshiko Maida, Mami Yasukawa, Miho Furuuchi, Timo Lassmann, Richard Possemato, Naoko Okamoto, et al.From:Nature (Vol. 461, Issue 7261) Peer-Reviewed

  Sept. 10, 20096,456 words Report 1490LConstitutive expression of telomerase in human cells prevents the onset of senescence and crisis by maintaining telomere homeostasis. However, accumulating evidence suggests that the human telomerase reverse...

• A Single Zidovudine (AZT) Administration Delays Hepatic Cell Proliferation by Altering Oxidative State in the Regenerating Rat Liver

  Authors:Armando Butanda-Ochoa, Diego Rolando Hernandez-Espinosa, Marisela Olguin-Martinez, Lourdes Sanchez-Sevilla, Mario R. Rodriguez, Benito Chavez-Renteria, et al.From:Oxidative Medicine and Cellular Longevity (Vol. 2017) Peer-Reviewed

  Annual 20177,997 words Article 1660LThe 3'-azido-3'-deoxythymidine or Zidovudine (AZT) was the first antiretroviral drug used in the treatment of HIV patients, which has good effectiveness but also hepatotoxic side effects that include cell cycle arrest...

• In Vitro HIV-1 Evolution in Response to Triple Reverse Transcriptase Inhibitors & In Silico Phenotypic Analysis

  Authors:Barbara A. Rath, Kaveh Pouran Yousef, David K. Katzenstein, Robert W. Shafer, Christof Schutte, Max von Kleist, et al.From:PLoS ONE (Vol. 8, Issue 4) Peer-Reviewed

  Apr. 17, 20139,271 words Article 1630LBackground Effectiveness of ART regimens strongly depends upon complex interactions between the selective pressure of drugs and the evolution of mutations that allow or restrict drug resistance. Methods Four...

• Efavirenz-Based Regimens in Antiretroviral-Naive HIV-Infected Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  Authors:Joanna Kryst, Pawel Kawalec, and Andrzej PilcFrom:PLoS ONE (Vol. 10, Issue 5) Peer-Reviewed

  May 1, 20158,690 words Clinical report 1460LEfavirenz, a non-nucleoside reverse-transcriptase inhibitor (NNRTI) is one of the most commonly prescribed antiretroviral drugs. The present article provides a systematic overview and meta-analysis of clinical trials...

• A novel method for banking stem cells from human exfoliated deciduous teeth: lentiviral TERT immortalization and phenotypical analysis

  Authors:Zhanhai Yin, Qi Wang, Ye Li, Hong Wei, Jianfeng Shi, and Ang LiFrom:Stem Cell Research & Therapy (Vol. 7, Issue 50) Peer-Reviewed

  Apr. 4, 20166,822 words Report 1390LBackground Stem cells from human exfoliated deciduous teeth (SHED) have recently attracted attention as novel multipotential stem cell sources. However, their application is limited due to in vitro replicative...

• Proteomic identification of proteins differentially expressed following overexpression of hTERT (human telomerase reverse transcriptase) in cancer cells

  Authors:Rishi Kumar Jaiswal, Pramod Kumar, Amod Sharma, Deepak Kumar Mishra, and Pramod Kumar YadavaFrom:PLoS ONE (Vol. 12, Issue 7) Peer-Reviewed

  July 13, 20175,761 words Report 1480LReverse transcriptase activity of telomerase adds telomeric repeat sequences at extreme ends of the newly replicated chromosome in actively dividing cells. Telomerase expression is not detected in terminally...

• Medical management of human immunodeficiency virus infection

  Author:John KempenFrom:Indian Journal of Ophthalmology (Vol. 56, Issue 5) Peer-Reviewed

  September-October 20084,366 words Article 1950LByline: John. Kempen The human immunodeficiency virus (HIV)/ acquired immune deficiency syndrome (AIDS) pandemic has pervasive effects on culture, economics, policy, and human development. All organs can be affected...

• In Vitro and Ex Vivo Inhibition of Human Telomerase by Anti-HIV Nucleoside Reverse Transcriptase Inhibitors (NRTIs) but Not by Non-NRTIs

  Authors:Kyle R. Hukezalie, Naresh R. Thumati, Helene C. F. Cote, and Judy M. Y. WongFrom:PLoS ONE (Vol. 7, Issue 11) Peer-Reviewed

  Nov. 15, 20127,408 words Article 1440LAuthor(s): Kyle R. Hukezalie 1 , 2 , Naresh R. Thumati 2 , Hélène C. F. Côté 1 , 3 , Judy M. Y. Wong 1 , 2 , * Introduction Linear chromosomes are capped by telomeres, nucleoprotein structures that protect...

• Transmission Patterns of HIV-Subtypes A/AE versus B: Inferring Risk-Behavior Trends and Treatment-Efficacy Limitations from Viral Genotypic Data Obtained Prior to and during Antiretroviral Therapy

  Authors:Boaz Avidor, Dan Turner, Zohar Mor, Shirley Chalom, Klaris Riesenberg, Eduardo Shahar, et al.From:PLoS ONE (Vol. 8, Issue 3) Peer-Reviewed

  Mar. 1, 20137,305 words Report 1470LAuthor(s): Boaz Avidor 1 , 2 , Dan Turner 1 , Zohar Mor 3 , Shirley Chalom 1 , Klaris Riesenberg 4 , Eduardo Shahar 5 , Shimon Pollack 5 , Daniel Elbirt 6 , Zev Sthoeger 6 , Shlomo Maayan 7 , Karen Olshtain-Pops 7 ,...

• Association between TERT rs2853669 polymorphism and cancer risk: A meta-analysis of 9,157 cases and 11,073 controls

  Authors:Zhengsheng Liu, Tao Wang, Zhun Wu, Kaiyan Zhang, Wei Li, Jianbin Yang, et al.From:PLoS ONE (Vol. 13, Issue 3) Peer-Reviewed

  Mar. 13, 20184,274 words Report 1280LAuthor(s): Zhengsheng Liu 1,2, Tao Wang 1, Zhun Wu 1, Kaiyan Zhang 1, Wei Li 1, Jianbin Yang 1,2, Chenxi Chen 1,2, Lei Chen 3, Jinchun Xing 1,* Introduction Telomeres are stretches of conserved, tandemly repeated...

• Global influenza surveillance network: laboratory surveillance and response to pandemic H1N1 2009/Mesures prises par les laboratoires du Reseau mondial de surveillance de la grippe pour faire face a la grippe pandemique H1N1 2009

  From:Weekly Epidemiological Record (Vol. 84, Issue 36)

  Sept. 4, 20093,428 words Article Background In response to the spread of the new influenza A (H1N1) virus, WHO declared pandemic influenza Phase 6 on 11 June 2009 (1) and organized a global response to this event with partners. Monitoring the...

• Recent advances in the treatment of HIV/AIDS

  Author:Corklin R. SteinhartFrom:Expert Review of Anti-infective Therapy (Vol. 2, Issue 2) Peer-Reviewed

  Mar. 20048,686 words Article In industrialized countries, highly active antiretroviral therapy has resulted in significant reductions in morbidity and mortality in patients with HIV/AIDS. At the same time, the management of the HIV-infected...

• Early Reverse Transcription Is Essential for Productive Foamy Virus Infection

  Authors:Alessia Zamborlini, Noemie Renault, Ali Saib, and Olivier DelelisFrom:PLoS ONE (Vol. 5, Issue 6) Peer-Reviewed

  June 11, 20105,299 words Article 1500LBackground Although viral RNA constitutes the majority of nucleic acids packaged in virions, a late occurring step of reverse transcription leads to the presence of infectious viral cDNA in foamy virus particles....

• First report of border disease virus in Melophagus ovinus (sheep ked) collected in Xinjiang, China

  Authors:Yong-Hong Liu, Bo He, Kai-Rui Li, Fei Li, Lu-Yao Zhang, Xian-Qiang Li, et al.From:PLoS ONE (Vol. 14, Issue 8) Peer-Reviewed

  Aug. 20, 20194,241 words Report 1370LMelophagus ovinus (sheep ked) is a blood-sucking ectoparasite that is parasitic primarily on sheep. It is widely distributed in different geographical regions worldwide. In China, it has been mainly found in Xinjiang,...

• High-Level Cross-Resistance to Didanosine Observed in South African Children Failing an Abacavir- or Stavudine-Based 1.sup.st-Line Regimen

  Authors:Kim Steegen, Leon Levin, Irene Ketseoglou, Michelle Bronze, Maria A. Papathanasopoulos, Sergio Carmona, et al.From:PLoS ONE (Vol. 9, Issue 5) Peer-Reviewed

  May 9, 20144,966 words Article 1460LBackground The knowledge-base of emerging drug resistance profiles in children exposed to abacavir-based antiretroviral regimens in South Africa is very limited. This study investigated the suitability of...