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    Academic Journals

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• Characterization of the glyoxalase I gene from the vascular wilt fungus Verticillium dahliae

  Authors:A. Klimes, M.J. Neumann, S.J. Grant, and K.F. DobinsonFrom:Canadian Journal of Microbiology (Vol. 52, Issue 9) Peer-Reviewed

  Sept. 20064,104 words Article 1740LAbstract: A glyoxalase I gene homologue (VdGLO1) was identified in the vascular wilt fungus Verticillium dahliae by sequence tag analysis of genes expressed during resting structure development. The results of the...

• Structural modeling identified the tRNA-binding domain of Utp8p, an essential nucleolar component of the nuclear tRNA export machinery of Saccharomyces cerevisiae

  Authors:Andrew T. McGuire, Robert A.B. Keates, Stephanie Cook, and Dev MangrooFrom:Biochemistry and Cell Biology (Vol. 87, Issue 2) Peer-Reviewed

  Apr. 20097,787 words Report Utp8p is an essential 80 kDa intranuclear tRNA chaperone that transports tRNAs from the nucleolus to the nuclear tRNA export receptors in Saccharomyces cerevisiae. To help understand the mechanism of Utp8p function,...

• High-resolution mapping of meiotic crossovers and non-crossovers in yeast

  Authors:Eugenio Mancera, Richard Bourgon, Alessandro Brozzi, Wolfgang Huber, and Lars M. SteinmetzFrom:Nature (Vol. 454, Issue 7202) Peer-Reviewed

  July 17, 20087,125 words Report 1480LMeiotic recombination has a central role in the evolution of sexually reproducing organisms. The two recombination outcomes, crossover and non-crossover, increase genetic diversity, but have the potential to homogenize...

• Asymmetrical Inheritance of Plasmids Depends on Dynamic Cellular Geometry and Volume Exclusion Effects

  Authors:Jai A. Denton, Atiyo Ghosh, and Tatiana T. Marquez-LagoFrom:PLoS ONE (Vol. 10, Issue 10) Peer-Reviewed

  Oct. 15, 20156,592 words Report 1400LThe asymmetrical inheritance of plasmid DNA, as well as other cellular components, has been shown to be involved in replicative aging. In Saccharomyces cerevisiae, there is an ongoing debate regarding the mechanisms...

• Studying Coxiella burnetii Type IV Substrates in the Yeast Saccharomyces cerevisiae: Focus on Subcellular Localization and Protein Aggregation

  Authors:Maria Rodriguez-Escudero, Victor J. Cid, Maria Molina, Jan Schulze-Luehrmann, Anja Luhrmann, and Isabel Rodriguez-EscuderoFrom:PLoS ONE (Vol. 11, Issue 1) Peer-Reviewed

  Jan. 28, 20169,773 words Report 1470LCoxiella burnetii is a Gram-negative obligate parasitic bacterium that causes the disease Q-fever in humans. To establish its intracellular niche, it utilizes the Icm/Dot type IVB secretion system (T4BSS) to inject...

• Mitochondrial dysfunction reduces yeast replicative lifespan by elevating RAS-dependent ROS production by the ER-localized NADPH oxidase Yno1

  Authors:Dae-Gwan Yi, Sujin Hong, and Won-Ki HuhFrom:PLoS ONE (Vol. 13, Issue 6) Peer-Reviewed

  June 18, 20188,478 words Report 1490LMitochondrial dysfunction leads to the accumulation of reactive oxygen species (ROS) which is associated with cellular dysfunction, disease etiology, and senescence. Here, we used the eukaryotic model Saccharomyces...

• Investigating the functionality of a ribosome-binding mutant of NAA15 using Saccharomyces cerevisiae

  Authors:Sylvia Varland and Thomas ArnesenFrom:BMC Research Notes (Vol. 11, Issue 1) Peer-Reviewed

  June 22, 20183,664 words Report 1480LObjective N-terminal acetylation is a common protein modification that occurs preferentially co-translationally as the substrate N-terminus is emerging from the ribosome. The major N-terminal acetyltransferase...

• Genome architecture and stability in the Saccharomyces cerevisiae knockout collection

  Authors:Fabio Puddu, Mareike Herzog, Alexandra Selivanova, Siyue Wang, Jin Zhu, Shir Klein-Lavi, et al.From:Nature (Vol. 573, Issue 7774) Peer-Reviewed

  Sept. 20199,870 words Technical report 1540LDespite major progress in defining the functional roles of genes, a complete understanding of their influences is far from being realized, even in relatively simple organisms. A major milestone in this direction arose...

• Oleaginicity of the yeast strain Saccharomyces cerevisiae D5A

  Authors:Qiaoning He, Yongfu Yang, Shihui Yang, Bryon S. Donohoe, Stefanie Van Wychen, Min Zhang, et al.From:Biotechnology for Biofuels (Vol. 11, Issue 1) Peer-Reviewed

  Sept. 24, 201810,332 words Report 1550LBackground The model yeast, Saccharomyces cerevisiae, is not known to be oleaginous. However, an industrial wild-type strain, D5A, was shown to accumulate over 20% storage lipids from glucose when growth is...

• The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1

  Authors:Piotr Sosnowski, Linas Urnavicius, Andreas Boland, Robert Fagiewicz, Johan Busselez, Gabor Papai, et al.From:eLife (Vol. 7) Peer-Reviewed

  Nov. 26, 201814,066 words Report 1310LThe biogenesis of 60S ribosomal subunits is initiated in the nucleus where rRNAs and proteins form pre-60S particles. These pre-60S particles mature by transiently interacting with various assembly factors. The ~5000...

• Generation of recombinant porcine parvovirus virus-like particles in saccharomyces cerevisiae and development of virus-specific monoclonal antibodies

  Authors:Paulius Lukas Tamosiunas, Rasa Petraityte-Burneikiene, Rita Lasickiene, Artiomas Akatov, Gabrielis Kundrotas, Vilimas Sereika, et al.From:Journal of Immunology Research (Vol. 2014) Peer-Reviewed

  Annual 20145,199 words Report 1390LPorcine parvovirus (PPV) is a widespread infectious virus that causes serious reproductive diseases of swine and death of piglets. The gene coding for the major capsid protein VP2 of PPV was amplified using viral...

• A yeast for all reasons: scientists have begun to overhaul a yeast's genome to make it more stable, engineerable and evolvable. Remarkably, the part-natural, part-synthetic yeast cells function and reproduce without obvious ill effects

  Authors:Peter J. Enyeart and Andrew D. EllingtonFrom:Nature (Vol. 477, Issue 7365) Peer-Reviewed

  Sept. 22, 2011988 words Article 1620LThe baker's yeast Saccharomyces cerevisiae is a model organism, and therefore one of the best-understood biological systems on the planet. Nevertheless, the Byzantine complexity of its inner workings still keeps...

• The pol3-t hyperrecombination phenotype and DNA damage-induced recombination in saccharomyces cerevisiae is RAD50 dependent

  Authors:Alvaro Galli, Kurt Hafer, Tiziana Cervelli, and Robert H. SchiestlFrom:Journal of Biomedicine and BiotechnologyPeer-Reviewed

  Annual 20095,931 words Report The DNA polymerase [delta] (POL3/CDC2) allele pol3-t of Saccharomyces cerevisiae has previously been shown to be sensitive to methylmethanesulfonate (MMS) and has been proposed to be involved in base excision repair....

• Analysis of the RNA content of the yeast Saccharomyces cerevisiae

  Authors:Charles E. Deutch and Pamela A. MarshallFrom:The American Biology Teacher (Vol. 70, Issue 9) Peer-Reviewed

  November-December 20085,033 words Report 1440LThe principles involved in the storage and expression of genetic information are now well established and have been incorporated into biology curricula for elementary, secondary, and college students (National Research...

• Pif1 family helicases suppress genome instability at G-quadruplex motifs

  Authors:Katrin Paeschke, Matthew L. Bochman, P. Daniela Garcia, Petr Cejka, Katherine L. Friedman, Stephen C. Kowalczykowski, et al.From:Nature (Vol. 497, Issue 7450) Peer-Reviewed

  May 20138,935 words Report 1450LThe Saccharomyces cerevisiae Pif1 helicase is the prototypical member of the Pif1 DNA helicase family, which is conserved from bacteria to humans. Here we show that exceptionally potent G-quadruplex unwinding is...

• Promiscuous activities of heterologous enzymes lead to unintended metabolic rerouting in Saccharomyces cerevisiae engineered to assimilate various sugars from renewable biomass

  Authors:Eun Ju Yun, Eun Joong Oh, Jing-Jing Liu, Sora Yu, Dong Hyun Kim, Suryang Kwak, et al.From:Biotechnology for Biofuels (Vol. 11, Issue 1) Peer-Reviewed

  May 14, 20186,415 words Author abstract 1600LBackground Understanding the global metabolic network, significantly perturbed upon promiscuous activities of foreign enzymes and different carbon sources, is crucial for systematic optimization of metabolic...

• Electrostatic lateral interactions drive ESCRT-III heteropolymer assembly

  Authors:Sudeep Banjade, Shaogeng Tang, Yousuf H Shah, and Scott D EmrFrom:eLife (Vol. 8) Peer-Reviewed

  June 27, 201914,388 words Report 1420LSelf-assembly of ESCRT-III complex is a critical step in all ESCRT-dependent events. ESCRT-III hetero-polymers adopt variable architectures, but the mechanisms of inter-subunit recognition in these hetero-polymers to...

• A Chemical and Enzymatic Approach to Study Site-Specific Sumoylation

  Authors:Claudio P. Albuquerque, Eyan Yeung, Shawn Ma, Ting Fu, Kevin D. Corbett, and Huilin ZhouFrom:PLoS ONE (Vol. 10, Issue 12) Peer-Reviewed

  Dec. 3, 20158,234 words Report 1510LA variety of cellular pathways are regulated by protein modifications with ubiquitin-family proteins. SUMO, the Small Ubiquitin-like MOdifier, is covalently attached to lysine on target proteins via a cascade reaction...

• Saccharomyces cerevisiae displays an increased growth rate and an extended replicative lifespan when grown under respiratory conditions in the presence of bacteria

  Authors:Paul A. Kirchman and Nicholas Van ZeeFrom:Canadian Journal of Microbiology (Vol. 63, Issue 9) Peer-Reviewed

  Sept. 20172,691 words Report 1610LIndividual cells of the budding yeast Saccharomyces cerevisiae have a limited replicative potential, referred to as the replicative lifespan. We have found that both the growth rate and average replicative lifespan of...

• Depletion of Saccharomyces cerevisiae in psoriasis patients, restored by Dimethylfumarate therapy (DMF)

  Authors:Hester Eppinga, H. Bing Thio, Marco W. J. Schreurs, Blerdi Blakaj, Ruena I. Tahitu, Sergey R. Konstantinov, et al.From:PLoS ONE (Vol. 12, Issue 5) Peer-Reviewed

  May 9, 20174,103 words Report 1370LBackground Psoriasis and inflammatory bowel disease (IBD) are chronic inflammatory diseases sharing similar pathogenic pathways. Intestinal microbial changes such as a decrease of bakers' yeast Saccharomyces...