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    Academic Journals

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• Association of polymorphism in rs2736990 of the a-synuclein gene with Parkinson's disease in a Chinese population

  Authors:Fenghua Pan, Haixia Ding, Hairong Dong, Min Ye, Weiguo Liu, Guiyun Cui, et al.From:Neurology India (Vol. 61, Issue 4) Peer-Reviewed

  July-August 20132,815 words Report 1570LByline: Fenghua. Pan, Haixia. Ding, Hairong. Dong, Min. Ye, Weiguo. Liu, Guiyun. Cui, Jiechun. Chen, Yanfeng. Wu, Hui. Wang, Xingzhen. Dai, Haicun. Shi, Xinsheng. Ding Background and Objective: Previous genetic...

• Single nucleotide polymorphic macrophage cytokine regulation by Mycobacterium tuberculosis and drug treatment

  Authors:Amit K Singh, Awadh Bihari Yadav, Rajiv Garg, and Amit MisraFrom:Pharmacogenomics (Vol. 15, Issue 4) Peer-Reviewed

  Mar. 20146,209 words Report 1470LAuthor(s): Amit K Singh 1 , Awadh Bihari Yadav 1 , Rajiv Garg 2 , Amit Misra [*] 3 KEYWORDS : inhalable microparticles; interleukin 10; interleukin 4; isoniazid; rifabutin; SNPs; tumor necrosis factor...

• Association study of single nucleotide polymorphisms in XRCC1 gene with risk of hepatocellular carcinoma in chinese han population

  Authors:Jingwang Bi, Chen Zhong, Kainan Li, Huili Chu, and Baocheng WangFrom:BioMed Research InternationalPeer-Reviewed

  Annual 20133,346 words Report 1400LHepatocellular carcinoma (HCC) is one of the most frequently causing cancer-related deaths worldwide. Previous evidence suggests that the X-ray repair cross-complementing group 1 gene (XRCC1) is an important candidate...

• CDKAL1-related single nucleotide polymorphisms are associated with insulin resistance in a cross-sectional cohort of Greek children

  Authors:Mathias Rask-Andersen, Gaetan Philippot, George Moschonis, George Dedoussis, Yannis Manios, Claude Marcus, et al.From:PLoS ONE (Vol. 9, Issue 4) Peer-Reviewed

  Apr. 20144,433 words Report 1430LFive novel loci recently found to be associated with body mass in two GWAS of East Asian populations were evaluated in two cohorts of Swedish and Greek children and adolescents. These loci are located within, or in the...

• SNP's and its correlation with hypertension: A comprehensive review

  Authors:Manohar Murugan, Karthikeyan Ramalingam, M. Nazzuredin, Hussain Rashed, and Ganesh PunamalaiFrom:Dentistry and Medical Research (Vol. 1, Issue 1) Peer-Reviewed

  January-June 20133,067 words Article 1760LByline: Manohar. Murugan, Karthikeyan. Ramalingam, M. Nazzuredin, Hussain. Rashed, Ganesh. Punamalai Hypertension is a growing global problem, which mostly affects the adults. It is a risk factor for death from...

• Genetic variation in Otos is associated with cisplatin-induced ototoxicity

  Authors:Timothy F Spracklen, Heather Whitehorn, Anna Alvera Vorster, Lebogang Ramma, Sameera Dalvie, and Rajkumar S RamesarFrom:Pharmacogenomics (Vol. 15, Issue 13) Peer-Reviewed

  Oct. 20146,242 words Report 1600LAuthor(s): Timothy F Spracklen aff1 , Heather Whitehorn aff1 , Anna Alvera Vorster aff1 , Lebogang Ramma aff2 , Sameera Dalvie aff3 , Rajkumar S Ramesar [*] aff1 Keywords: cisplatin; hearing loss; Otos ;...

• Monogenic lupus

  Authors:Mindy S Lo and George C TsokosFrom:International Journal of Clinical Rheumatology (Vol. 9, Issue 6) Peer-Reviewed

  Dec. 20142,785 words Editorial 1760LAuthor(s): Mindy S Lo aff1 , George C Tsokos aff2 Keywords: chilblain; complement; DNASE1L3; immunodeficiency; lupus; Mendelian; monogenic; PRKCD; systemic lupus erythematosus; TREX1 Lupus has long been...

• Association of ATM gene polymorphism with PTC metastasis in female patients

  Authors:Yulu Gu, Xiaoli Liu, Yaqin Yu, Jieping Shi, Lizhe Ai, Hui Sun, et al.From:International Journal of EndocrinologyPeer-Reviewed

  Annual 20144,075 words Report 1460LAtaxia telangiectasia mutated (ATM) gene is critical in the process of recognizing and repairing DNA lesions and is related to invasion and metastasis of malignancy The incidence rate of papillary thyroid cancer (PTC)...

• Translating genetic risk factors for prostate cancer to the clinic: 2013 and beyond

  Authors:Christos Mikropoulos, Chee Goh, Daniel Leongamornlert, Zsofia Kote-Jarai, and Rosalind EelesFrom:Future Oncology (Vol. 10, Issue 9) Peer-Reviewed

  July 201411,429 words Report 1820LAuthor(s): Christos Mikropoulos [*] aff1 , Chee Goh aff1 , Daniel Leongamornlert aff1 , Zsofia Kote-Jarai aff1 , Rosalind Eeles aff1 aff2 KEYWORDS biomarkers; fine-mapping; imputation; single nucleotide...

• Lack of association between rs211037 of the GABRG2 gene and juvenile myoclonic epilepsy in Brazilian population

  Authors:Delma De Almeida, Fernando Gameleira, Tiago De Andrade, and Luciana MachadoFrom:Neurology India (Vol. 60, Issue 6) Peer-Reviewed

  November-December 20122,941 words Report 1580LByline: Livia. Gitai, Delma. de Almeida, Joao Paulo. Born, Fernando. Gameleira, Tiago. de Andrade, Luciana. Machado, Daniel. Gitai Background: Juvenile myoclonic epilepsy (JME) is an idiopathic generalized epilepsy...

• Matrix metalloproteinase-2 gene polymorphism is not associated with increased glioblastoma multiforme susceptibility: An Indian institutional experience

  Authors:Raj Kumar, Nitin Malik, Arun Tungaria, and Priyanka KawalFrom:Neurology India (Vol. 59, Issue 2) Peer-Reviewed

  March-April 20113,147 words Clinical report 1490LByline: Raj. Kumar, Nitin. Malik, Arun. Tungaria, Priyanka. Kawal Background: Glioblastoma multiforme (GBM) is a highly malignant central nervous system tumor that is extremely refractory to therapy due to its rapid...

• Polymorphisms in SLCO1B3 and NR1I2 as genetic determinants of hematotoxicity of carboplatin and paclitaxel combination

  Authors:Litaty Cephanoee Mbatchi, Antonin Schmitt, Fabienne Thomas, Yoann Cazaubon, Jacques Robert, Serge Lumbroso, et al.From:Pharmacogenomics (Vol. 16, Issue 13) Peer-Reviewed

  Aug. 20156,973 words Report 1530LAuthor(s): Litaty Céphanoée Mbatchi aff1 aff2 aff3 , Antonin Schmitt aff4 , Fabienne Thomas aff4 , Yoann Cazaubon aff3 , Jacques Robert aff5 , Serge Lumbroso aff1 , Jean-Paul Brouillet aff1 aff2 , Philippe Pourquier...

• Challenges and recommendations for conducting epidemiological studies in the field of epilepsy pharmacogenetics

  Authors:Sandeep Grover, Meenal Gupta, and Ritushree KukretiFrom:Indian Journal of Human Genetics (Vol. 17, Issue 4) Peer-Reviewed

  May 20114,807 words Report 1790LByline: Sandeep. Grover, Meenal. Gupta, Ritushree. Kukreti Epilepsy is one of the most prevalent neurological disorders, afflicting approximately 50 million Indians. Owing to affordability and easy availability, use...

• Effect of genetic polymorphisms on therapeutic response and clinical outcomes in pancreatic cancer patients treated with gemcitabine

  Authors:Hye In Woo, Ka-Kyung Kim, Hangseok Choi, Seonwoo Kim, Kee-Taek Jang, Jun Ho Yi, et al.From:Pharmacogenomics (Vol. 13, Issue 9) Peer-Reviewed

  July 20127,149 words Report 1470LAuthor(s): Hye In Woo 1 , Ka-Kyung Kim 1 2 , Hangseok Choi 3 , Seonwoo Kim 3 , Kee-Taek Jang 4 , Jun Ho Yi 5 , Young Suk Park 5 , Joon Oh Park [*] 7 , Soo-Youn Lee [*] 6 KEYWORDS : CMPK1; gemcitabine;...

• Genetic variation in the SLC19A1 gene and methotrexate toxicity in rheumatoid arthritis patients

  Authors:Petra Bohanec Grabar, Luis J Leandro-Garcia, Lucia Inglada-Perez, Cristina Rodriguez-Antona, and Vita DolzanFrom:Pharmacogenomics (Vol. 13, Issue 14) Peer-Reviewed

  Nov. 20126,692 words Report 1430LAuthor(s): Petra Bohanec Grabar 1 , Luis J Leandro-García 2 , Lucía Inglada-Pérez 2 3 , Dušan Logar 4 , Cristina Rodríguez-Antona 2 3 , Vita Dolzan [*] 5 KEYWORDS : methotrexate; polymorphism; reduced...

• Accuracy of NAT2 SNP genotyping panels to infer acetylator phenotypes in African, Asian, Amerindian and admixed populations

  Authors:Guilherme Suarez-Kurtz, Daniela D Vargens, Vinicius A Sortica, and Mara H HutzFrom:Pharmacogenomics (Vol. 13, Issue 8) Peer-Reviewed

  June 20121,917 words Report 1650LAuthor(s): Guilherme Suarez-Kurtz [*] 3 , Daniela D Vargens 1 , Vinicius A Sortica 2 , Mara H Hutz 2 In a recent article in Pharmacogenomics , Hein and Doll assessed the accuracy of different genotyping panels to...

• Association of DHODH haplotype variants and response to leflunomide treatment in rheumatoid arthritis

  Authors:Catherine O'Doherty, Matthew Schnabl, Llewellyn Spargo, Leslie G Cleland, Michael James, Susanna M Proudman, et al.From:Pharmacogenomics (Vol. 13, Issue 2) Peer-Reviewed

  Sept. 20124,437 words Report 1400LAuthor(s): Catherine O'Doherty 1 , Matthew Schnabl 1 , Llewellyn Spargo 2 , Leslie G Cleland 2 3 , Michael James 2 3 , Susanna M Proudman 2 3 , Michael D Wiese [*] 4 KEYWORDS : DHODH; leflunomide;...

• Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I

  From:Molecular Diagnosis & Therapy (Vol. 14, Issue 4) Peer-Reviewed

  July-August 2010461 words Report 1320LThe calcineurin inhibitors ciclosporin (cyclosporine) and tacrolimus are immunosuppressant drugs used for the prevention of organ rejection following transplantation. Both agents are metabolic substrates for cytochrome...

• Pharmacogenetic influences on mycophenolate therapy

  Authors:Katherine A Barraclough, Katie J Lee, and Christine E StaatzFrom:Pharmacogenomics (Vol. 11, Issue 3) Peer-Reviewed

  Mar. 201014,700 words Report Author(s): Katherine A Barraclough [[dagger]] 1 , Katie J Lee 2 , Christine E Staatz 2 KEYWORDS: mycophenolate; mycophenolic acid; pharmacodynamics; pharmacogenetics; pharmacogenomics; pharmacokinetics;...

• Role of warfarin pharmacogenetic testing in clinical practice

  Authors:Guang-Ming Tan, Enoch Wu, Yat-Yin Lam, and Bryan P YanFrom:Pharmacogenomics (Vol. 11, Issue 3) Peer-Reviewed

  Mar. 20106,396 words Report Author(s): Guang-Ming Tan 1 , Enoch Wu 1 , Yat-Yin Lam 1 2 , Bryan P Yan [[dagger]] 1 2 KEYWORDS: anticoagulation therapy; CYP2C9 ; pharmacogenetics; polymorphism; VKORC1 ; warfarin For over 60 years, chronic...