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Academic Journals
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From:PLoS ONE (Vol. 9, Issue 4) Peer-ReviewedFive novel loci recently found to be associated with body mass in two GWAS of East Asian populations were evaluated in two cohorts of Swedish and Greek children and adolescents. These loci are located within, or in the...
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From:Dentistry and Medical Research (Vol. 1, Issue 1) Peer-ReviewedByline: Manohar. Murugan, Karthikeyan. Ramalingam, M. Nazzuredin, Hussain. Rashed, Ganesh. Punamalai Hypertension is a growing global problem, which mostly affects the adults. It is a risk factor for death from...
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From:Pharmacogenomics (Vol. 15, Issue 13) Peer-ReviewedAuthor(s): Timothy F Spracklen aff1 , Heather Whitehorn aff1 , Anna Alvera Vorster aff1 , Lebogang Ramma aff2 , Sameera Dalvie aff3 , Rajkumar S Ramesar [*] aff1 Keywords: cisplatin; hearing loss; Otos ;...
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From:Neurology India (Vol. 60, Issue 6) Peer-ReviewedByline: Livia. Gitai, Delma. de Almeida, Joao Paulo. Born, Fernando. Gameleira, Tiago. de Andrade, Luciana. Machado, Daniel. Gitai Background: Juvenile myoclonic epilepsy (JME) is an idiopathic generalized epilepsy...
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From:Neurology India (Vol. 59, Issue 2) Peer-ReviewedByline: Raj. Kumar, Nitin. Malik, Arun. Tungaria, Priyanka. Kawal Background: Glioblastoma multiforme (GBM) is a highly malignant central nervous system tumor that is extremely refractory to therapy due to its rapid...
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From:Indian Journal of Human Genetics (Vol. 17, Issue 4) Peer-ReviewedByline: Sandeep. Grover, Meenal. Gupta, Ritushree. Kukreti Epilepsy is one of the most prevalent neurological disorders, afflicting approximately 50 million Indians. Owing to affordability and easy availability, use...
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From:Pharmacogenomics (Vol. 13, Issue 8) Peer-ReviewedAuthor(s): Guilherme Suarez-Kurtz [*] 3 , Daniela D Vargens 1 , Vinicius A Sortica 2 , Mara H Hutz 2 In a recent article in Pharmacogenomics , Hein and Doll assessed the accuracy of different genotyping panels to...
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From:Molecular Diagnosis & Therapy (Vol. 14, Issue 4) Peer-ReviewedThe calcineurin inhibitors ciclosporin (cyclosporine) and tacrolimus are immunosuppressant drugs used for the prevention of organ rejection following transplantation. Both agents are metabolic substrates for cytochrome...
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From:Epigenomics (Vol. 2, Issue 2) Peer-ReviewedThis finding will have an impact on our understanding of the origins of individual phenotypic differences and will have implications for future genetic studies of complex disease. The February 2010 issue of the...
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From:Diabetes (Vol. 57, Issue 2) Peer-ReviewedOBJECTIVE--In recent genome-wide association studies, two single nucleotide polymorphisms (SNPs) near the HHEX locus were shown to be more frequent in type 2 diabetic patients than in control subjects. Based on HHEX's...
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From:Diabetes (Vol. 58, Issue 12) Peer-ReviewedOBJECTIVE--The goal of this study was to investigate whether the effects of common genetic variants associated with fasting glucose in adults are detectable in healthy children. RESEARCH DESIGN AND METHODS--Single...
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From:Diabetes (Vol. 56, Issue 1) Peer-ReviewedMore than 120 published reports have described associations between single nucleotide polymorphisms (SNPs) and type 2 diabetes. However, multiple studies of the same variant have often been discordant. From a literature...
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From:Pharmacogenomics (Vol. 7, Issue 3) Peer-ReviewedAuthor(s): Olivier Delrieu, Clive Bowman [[dagger]] 1 Keywords: Bayes; case-control study; disease; drug discovery; filter; gene; individualization; multivariate method; population heterogeneity; single nucleotide...
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From:Pharmacogenomics (Vol. 3, Issue 3) Peer-ReviewedWe derive and compare several estimates of the number of SNPs that would be required to form the basis of a complete haplotype survey of the human genome. Our estimates make use of reports published by Stephens et al....
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From:BioMed Research InternationalPeer-ReviewedObjective. Venous thromboembolism (VTE) is a multifactorial disorder and, worldwide, the most important cause of morbidity and mortality. Genetic factors play a critical role in its aetiology. Microsatellites are the...
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From:Alcohol Research: Current Reviews (Vol. 34, Issue 3) Peer-ReviewedThe effects of beverage alcohol (ethanol) on the body are determined largely by the rate at which it and its main breakdown product, acetaldehyde, are metabolized after consumption. The main metabolic pathway for...
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From:PLoS ONE (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Hui Zhang 1 , 2 , Xiaoxiang Hu 3 , Zhipeng Wang 1 , 2 , Yuandan Zhang 4 , Shouzhi Wang 1 , 2 , Ning Wang 1 , 2 , Li Ma 5 , Li Leng 1 , 2 , Shengwen Wang 5 , Qigui Wang 1 , 2 , Yuxiang Wang 1 , 2 , Zhiquan...
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From:PLoS ONE (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Jeffrey A. Rosenfeld 1 , 2 , Christopher E. Mason 3 , 4 , Todd M. Smith 5 , * Introduction A primary goal of the human genome project was to produce a high quality DNA sequence that could serve as a...
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From:PLoS ONE (Vol. 7, Issue 12) Peer-ReviewedAuthor(s): Yongshuai Jiang 1 , Ruijie Zhang 1 , * , Jiajia Zheng 1 , Panpan Liu 1 , Guoping Tang 1 , Hongchao Lv 1 , Lanying Zhang 1 , Zhenwei Shang 1 , Yuanbo Zhan 2 , Wenhua Lv 1 , Miao Shi 1 , Ruimin Zhang 2 , *...
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From:PLoS ONE (Vol. 7, Issue 6) Peer-ReviewedAuthor(s): Anokhi Ali Khan 1 , Alina Rodriguez 1 , 2 , 3 , Sylvain Sebert 1 , 4 , Marika Kaakinen 4 , 5 , Stéphane Cauchi 6 , Philippe Froguel 6 , 7 , Anna-Liisa Hartikainen 8 , Anneli Pouta 8 , 9 , Marjo-Riitta...